D:Liver Disease

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Disease Term
Synonyms Disease Liver, DISEASES LIVER, Dysfunction Liver, DYSFUNCTIONS LIVER, LIVER DISEASES, Liver Disorder, LIVER DISORDERS, Liver Dysfunction, Liver Dysfunctions
Documents 2056
Hot Single Events 200
Hot Interactions 74

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Liver Disease. They are ordered first by their relevance to Liver Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT280006 Binding of CLTC and IFNA1 1 0.04 1.59 0 100.00
2 INT252785 ELANE Regulation of Gene_expression of FBRS 1 0.00 0.5 0.13 100.00
3 INT326587 GYPA Regulation of DDC 1 0.08 0.83 0.33 99.20
4 INT260728 Binding of Samsn1 and NAFLD2 1 0.00 1.15 0.05 99.18
5 INT351856 Ccl4 Positive_regulation of Alb 1 0.28 0.4 0.05 99.12
6 INT355866 Binding of EXT1 and Afp 1 0.04 3.56 0 98.60
7 INT355867 Binding of Afp and HCC 1 0.01 2.25 0.14 98.60
8 INT355864 EXT1 Positive_regulation of Positive_regulation of Afp 1 0.05 0.93 0 98.56
9 INT198022 AKT1 Regulation of Gene_expression of MCL1 1 0.15 2.25 0 98.04
10 INT198020 PIK3CA Regulation of Gene_expression of MCL1 1 0.16 2.25 0 98.04
11 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 97.92
12 INT265877 IGF1 Regulation of Binding of GH1 and IGF1 1 0.03 0.47 0.07 97.92
13 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 97.32
14 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05 96.68
15 INT183750 Binding of EPO and TF 1 0.42 1.21 0 96.48
16 INT343569 Negative_regulation of Synm Positive_regulation of Gpt 1 0.01 0.96 0.29 96.32
17 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66 96.04
18 INT355865 EXT1 Positive_regulation of Cm3 1 0.04 0.99 0 95.56
19 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 95.48
20 INT348011 Binding of Samsn1 and Vps54 1 0.00 1.35 0.11 95.36
21 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24 95.28
22 INT312573 AMBP Negative_regulation of IL6 1 0.11 1.41 0.32 95.24
23 INT312571 AMBP Negative_regulation of Positive_regulation of IL6 1 0.11 1.41 0.32 95.24
24 INT312794 Hdl1 Regulation of Pon1 1 0.02 1.63 0.15 94.80
25 INT329224 Prkag1 Positive_regulation of Localization of Ins1 1 0.03 1.14 0 94.28
26 INT252823 Binding of TNF and SIGMAR1 1 0.01 0.95 0.05 94.16
27 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29 93.84
28 INT343571 Synm Positive_regulation of ALPP 1 0.01 1.28 0.28 93.44
29 INT191432 Binding of COX10 and EDIL3 1 0.01 1.79 0.1 93.44
30 INT343570 Synm Positive_regulation of Gpt 1 0.01 1.28 0.28 93.04
31 INT212442 HGF Positive_regulation of MET 2 0.21 1.25 0.04 92.72
32 INT343573 Synm Positive_regulation of SLC17A5 1 0.17 1.28 0.28 92.64
33 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27 91.84
34 INT232898 Binding of KRT1 and Krt8 1 0.27 1.22 0 90.08
35 INT232889 Binding of Krt18 and Krt8 1 0.22 1.09 0 90.08
36 INT244709 Binding of Ldha and Gpt 1 0.01 1.32 0 89.52
37 INT251702 Fig4 Regulation of Positive_regulation of Ache 1 0.07 0.42 0 89.28
38 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25 88.88
39 INT301620 Positive_regulation of Binding of Ros1 and Scd1 1 0.03 0.41 0 88.68
40 INT301634 Positive_regulation of Binding of Ros1 and Cyb5 1 0.00 0.41 0 88.68
41 INT301082 Binding of BCS1L and TARM1 1 0.17 1.21 0 88.60
42 INT180345 Binding of HLA-DMA and HLA-DRB4 1 0.00 1.51 0.12 88.36
43 INT301633 Binding of Ros1 and Cyb5 1 0.00 0.41 0 88.28
44 INT301652 Binding of Ros1 and Scd1 1 0.02 0.41 0 88.28
45 INT312792 Binding of Pon1 and Hdl1 1 0.04 1.85 0.11 87.60
46 INT301615 Binding of Cyp2e1 and Samsn1 1 0.02 2.42 0.18 87.48
47 INT348024 Binding of Chuk and Traf3 1 0.13 0.65 0.04 85.60
48 INT270566 IGHE Regulation of IL4 1 0.21 0.99 0.09 85.16
49 INT270567 IGHE Regulation of IL13RA2 1 0.23 0.99 0.09 85.16
50 INT270569 IGHE Regulation of IL5 1 0.18 1.04 0.09 85.16
51 INT186502 Binding of AMELX and HLA-A 1 0.00 0.71 0 84.40
52 INT333397 CFD Negative_regulation of Gene_expression of Nos2 1 0.04 0.8 0.22 84.32
53 INT353544 Egf Regulation of Gene_expression of ONECUT1 1 0.00 0.08 0 84.32
54 INT353542 Pik3cb Regulation of Gene_expression of ONECUT1 1 0.00 0.08 0 84.32
55 INT353543 Hgf Regulation of Gene_expression of ONECUT1 1 0.00 0.08 0 84.32
56 INT252794 Binding of IL8 and TNF 1 0.02 0.75 0.25 84.00
57 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25 84.00
58 INT252804 TNF Regulation of Positive_regulation of FOS 1 0.01 0.76 0.25 84.00
59 INT252793 TNF Positive_regulation of Positive_regulation of FOS 1 0.02 0.76 0.25 84.00
60 INT252797 ROS1 Positive_regulation of Positive_regulation of FAS 1 0.08 1.03 0.04 83.92
61 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 83.76
62 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22 83.12
63 INT343918 IgG Positive_regulation of Phosphorylation of MAPK1 1 0.01 3.57 0.91 82.88
64 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91 82.88
65 INT252795 IL8 Positive_regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 82.72
66 INT252816 IL8 Regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 82.72
67 INT252822 CCL2 Positive_regulation of Positive_regulation of FOS 1 0.04 0.75 0.25 82.04
68 INT252786 CCL2 Regulation of Positive_regulation of FOS 1 0.05 0.75 0.25 82.04
69 INT348028 Binding of Traf3 and Ticam1 1 0.01 0.56 0.03 81.92
70 INT301637 Positive_regulation of Ros1 Positive_regulation of Phosphorylation of Ins1 1 0.00 0.91 0.1 81.28
71 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04 81.24
72 INT353540 Egf Positive_regulation of Hgf 1 0.23 0.08 0 80.80
73 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0 80.20
74 INT252776 ELANE Regulation of Gene_expression of COL1A1 1 0.01 0.58 0 80.20
75 INT252802 ROS1 Regulation of Gene_expression of COL1A1 1 0.05 0.58 0 79.88
76 INT301661 Binding of CYP2B6 and Ros1 1 0.02 0.64 0.04 79.28
77 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 79.16
78 INT301668 Ltb4r1 Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 78.56
79 INT348032 Fndc3b Positive_regulation of Tlr2 1 0.01 1.3 0.2 78.52
80 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 78.24
81 INT301497 UBXN11 Negative_regulation of CYP4F3 1 0.37 0.69 0.05 77.76
82 INT301496 PPA1 Negative_regulation of CYP4F3 1 0.01 0.69 0.05 77.44
83 INT252768 TNF Regulation of Tnfrsf1a 1 0.01 1.02 0.04 77.44
84 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23 77.36
85 INT348021 Stat3 Regulation of Vps54 1 0.02 1.32 0.07 77.12
86 INT180346 Binding of PRTN3 and SMN1 1 0.00 3.22 0 77.08
87 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13 76.92
88 INT232814 Mocos Positive_regulation of Gene_expression of Tlr4 1 0.19 0.9 0.05 76.08
89 INT240903 Mapk8 Positive_regulation of Ros1 2 0.09 1.01 0.1 75.76
90 INT287612 Binding of Fmr1 and Dnajc13 1 0.01 0.84 0 75.40
91 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19 75.00
92 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85 74.88
93 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42 74.88
94 INT212584 IFNA1 Regulation of Gene_expression of CD4 1 0.21 0.98 0.03 74.20
95 INT348014 Binding of Tbk1 and Gramd3 1 0.00 1.33 0.2 73.72
96 INT252808 TNF Positive_regulation of NOX1 1 0.06 1.03 0.04 73.52
97 INT301670 Binding of CYP4F2 and Cyp4f18 1 0.02 1.04 0.27 73.08
98 INT301627 Binding of Fabp1 and Ppara 1 0.21 0.49 0.04 72.84
99 INT252774 ROS1 Regulation of FUT1 1 0.04 0.57 0 72.08
100 INT252796 ELANE Regulation of COL1A1 1 0.01 0.57 0 72.08
101 INT252773 ROS1 Positive_regulation of COL1A1 1 0.05 0.57 0 72.08
102 INT252771 ELANE Regulation of FBN1 1 0.00 0.57 0 72.08
103 INT252800 ROS1 Regulation of COL1A1 1 0.05 0.57 0 72.08
104 INT252813 ELANE Positive_regulation of COL1A1 1 0.01 0.57 0 72.08
105 INT252811 ELANE Regulation of FUT1 1 0.01 0.57 0 72.08
106 INT252824 ROS1 Regulation of FBN1 1 0.00 0.57 0 72.08
107 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38 71.92
108 INT348013 Negative_regulation of Binding of Irf3 and Tbk1 1 0.21 1.41 0.2 71.52
109 INT180372 CYP2A6 Regulation of Cyp1a2 1 0.03 2.02 0.05 71.48
110 INT348031 Binding of Irf3 and Tbk1 1 0.17 2.82 0.4 71.12
111 INT348041 Binding of IFNA1 and Irf3 1 0.02 1.41 0.2 70.92
112 INT229420 Atp6v0a2 Negative_regulation of Ros1 1 0.00 1.13 0.04 70.72
113 INT180344 CYP2A6 Regulation of AMELX 1 0.01 2.01 0.05 70.52
114 INT180373 CYP2A6 Regulation of Cyp2d4 1 0.05 2.01 0.05 70.52
115 INT180348 CYP2A6 Regulation of AIRE 1 0.01 2.01 0.05 70.52
116 INT141242 Binding of SYP and DNLZ 1 0.29 1.74 0.41 70.20
117 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 69.92
118 INT332587 MND1 Positive_regulation of Binding of RAPH1 and MND1 1 0.00 2.21 0.03 69.92
119 INT343859 Binding of IRF6 and TBCE 1 0.01 1.1 0.51 69.76
120 INT343860 Binding of CD14 and TBCE 1 0.03 1.1 0.51 69.76
121 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14 69.04
122 INT343834 Binding of CD14 and IRF6 1 0.02 2.08 0.9 68.80
123 INT348027 Gramd3 Negative_regulation of Irf3 1 0.00 1.39 0.2 68.24
124 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1 67.48
125 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87 66.52
126 INT251706 Chat Regulation of Gene_expression of Acot1 1 0.06 1.64 0.85 66.52
127 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2 66.40
128 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2 66.40
129 INT251708 Chat Regulation of Acot1 1 0.03 1.64 0.84 66.12
130 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25 65.36
131 INT251705 Fig4 Regulation of Localization of Chat 1 0.05 0.23 0.08 64.40
132 INT251703 Fig4 Regulation of Localization of Ache 1 0.07 0.23 0.08 64.40
133 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 64.08
134 INT301664 UBXN11 Positive_regulation of Negative_regulation of Cpt1a 1 0.27 0.37 0 63.84
135 INT339676 CSF2 Positive_regulation of HGF 1 0.08 0.46 0 63.80
136 INT251712 Fig4 Regulation of Ache 1 0.02 0.23 0.08 63.68
137 INT251710 Fig4 Regulation of Chat 1 0.03 0.23 0.08 63.32
138 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0 61.44
139 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64 60.32
140 INT355540 Gnptg Positive_regulation of AMELX 1 0.00 2.16 0.44 59.36
141 INT278243 HGF Positive_regulation of Gene_expression of Hsdr1 1 0.00 0.4 0.06 58.48
142 INT348035 Map3k7 Positive_regulation of Binding of Chuk 1 0.20 0.06 0 58.32
143 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62 58.00
144 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19 57.92
145 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62 57.68
146 INT348018 Map3k7 Positive_regulation of Chuk 1 0.19 0.06 0 57.68
147 INT344720 Niacr1 Negative_regulation of Binding of Hdl1 1 0.17 1.13 0 57.28
148 INT252787 Binding of FCGR3B and ROS1 1 0.06 0.58 0.2 57.20
149 INT252817 Binding of CD8A and IL12A 1 0.02 1.36 0.19 57.20
150 INT287609 Fmr1 Regulation of Protein_catabolism of Dlg4 1 0.05 0.06 0 56.84
151 INT287619 Fmr1 Regulation of Dlg4 1 0.12 0.06 0 56.84
152 INT227303 Zbp1 Regulation of Transcription of Baat 1 0.09 1.43 0.08 56.72
153 INT227301 Zbp1 Regulation of Transcription of Ucp1 1 0.19 1.42 0.08 56.72
154 INT227304 Zbp1 Regulation of Transcription of Ucp2 1 0.17 1.43 0.08 56.72
155 INT355539 Gnptg Positive_regulation of Mmp23 1 0.00 1.18 0.35 55.64
156 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19 53.76
157 INT354888 Amy1 Regulation of Il10 1 0.02 1.41 0.13 52.68
158 INT354885 Amy1 Regulation of Gene_expression of Il10 1 0.03 1.41 0.13 52.68
159 INT20203 Positive_regulation of Binding of TAT and Fgf12 1 0.01 1.51 0.17 51.64
160 INT258492 Binding of Ins1 and Cdipt 1 0.00 0.92 0 51.64
161 INT20202 Binding of TAT and Fgf12 1 0.01 1.5 0.17 50.84
162 INT348045 Irak2 Positive_regulation of Binding of Traf6 and Irak2 1 0.11 0.05 0 50.40
163 INT348020 Binding of Traf6 and Irak2 1 0.13 0.05 0 50.40
164 INT348037 Irak2 Positive_regulation of Binding of Traf6 1 0.18 0.05 0 50.40
165 INT339675 CSF2 Positive_regulation of Localization of FUT1 1 0.01 0.42 0 50.00
166 INT301656 Ins1 Positive_regulation of Srebf1 1 0.02 0.73 0.07 49.24
167 INT301629 Ins1 Positive_regulation of Mlxipl 1 0.00 0.36 0 49.24
168 INT301645 Binding of Alb and Slc27a1 1 0.02 0.38 0.08 48.80
169 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08 48.80
170 INT301613 Binding of Fabp4 and Cd36 1 0.05 0.38 0.08 48.32
171 INT301651 Binding of Alb and Fabp4 1 0.01 0.38 0.08 48.32
172 INT252791 Binding of IREB2 and TFRC 1 0.02 1.82 0 47.68
173 INT252807 Binding of ACO1 and TFRC 1 0.01 1.83 0 47.68
174 INT326583 GYPA Negative_regulation of Binding of GYPA and SLC6A3 1 0.03 0.22 0.22 46.84
175 INT262289 Regulation of Binding of PPIG and CC2D1A 1 0.01 1.52 0.13 46.84
176 INT262290 Binding of PPIG and CC2D1A 1 0.01 1.52 0.13 46.44
177 INT232902 Binding of YWHAQ and Krt18 1 0.34 0.96 0.07 46.40
178 INT232901 Regulation of Binding of YWHAQ and Krt18 1 0.41 0.96 0.07 46.40
179 INT234724 Binding of NPC1 and Cxcl1 1 0.00 0.33 0.21 46.12
180 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22 45.76
181 INT156749 Gpt Positive_regulation of Gene_expression of Gpt2 1 0.50 0.22 0.1 45.76
182 INT156750 Gpt Positive_regulation of Gpt 1 0.27 0.22 0.1 45.76
183 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 45.60
184 INT156751 Gpt2 Positive_regulation of Gpt 1 0.12 0.21 0.1 45.40
185 INT236016 ROS1 Positive_regulation of MAPK8 2 0.18 1.81 0 44.68
186 INT343836 Binding of IRF6 and LBP 1 0.02 0.8 0.14 43.64
187 INT348039 Binding of Myd88 and Irak2 1 0.22 0 0 43.60
188 INT334266 Binding of Irak1 and Myd88 2 0.35 0.16 0.09 42.48
189 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36 42.40
190 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 42.08
191 INT334258 Binding of Myd88 and Irak4 2 0.26 0.24 0.05 41.92
192 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 40.24
193 INT229422 Atp6v0a2 Regulation of Mpo 1 0.03 3.39 0.15 40.20
194 INT252783 ROS1 Negative_regulation of MAPK8 1 0.05 0.77 0 39.52
195 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62 39.44
196 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39 38.56
197 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38 38.56
198 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12 37.32
199 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12 37.32
200 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0 37.20

Single Events

The table below shows the top 200 pain related interactions that have been reported for Liver Disease. They are ordered first by their pain relevance and then by number of times they were reported in Liver Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT282679 Localization of FECH 1 0.12 9.57 0.23 100.00
2 INT240765 Positive_regulation of Pon1 16 0.67 12.06 0.48 100.00
3 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 100.00
4 INT113659 Gene_expression of ABR 19 0.65 8.49 1.45 100.00
5 INT39914 Negative_regulation of Cyp1a2 44 0.58 10.04 22 100.00
6 INT245847 Localization of Tir1 1 0.56 4.88 0 100.00
7 INT312771 Negative_regulation of Positive_regulation of CETP 1 0.13 1.76 0 100.00
8 INT170853 Positive_regulation of Gene_expression of CFD 7 0.23 9.89 1.41 100.00
9 INT310728 Binding of DKC1 1 0.25 2.36 0.38 100.00
10 INT312777 Negative_regulation of Positive_regulation of Pltp 1 0.16 0.89 0 100.00
11 INT173717 Gene_expression of Ccl4 22 0.65 13.98 1.47 100.00
12 INT312774 Positive_regulation of Gene_expression of Ccl4 3 0.42 1.3 0.1 100.00
13 INT227414 Localization of DLAT 2 0.49 5.14 0.26 100.00
14 INT283498 Negative_regulation of Localization of DLAT 1 0.28 1.77 0.14 100.00
15 INT64743 Positive_regulation of olt 19 0.40 16.46 3.86 99.98
16 INT285395 Binding of R3hcc1 4 0.16 3.34 0.19 99.96
17 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 99.96
18 INT61644 Gene_expression of Gc 16 0.70 11.35 1.95 99.92
19 INT115264 Binding of FECH 9 0.41 7.93 1.1 99.92
20 INT170470 Binding of CD14 27 0.35 14.89 5.16 99.92
21 INT47055 Gene_expression of RBP1 8 0.75 7.85 0.86 99.92
22 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68 99.92
23 INT47056 Negative_regulation of Gene_expression of RBP1 2 0.41 2.35 0.31 99.92
24 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 99.90
25 INT61645 Negative_regulation of Gc 15 0.51 10.44 2.71 99.90
26 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 99.90
27 INT152506 Negative_regulation of Gene_expression of Gc 2 0.33 2.29 0.41 99.90
28 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 99.90
29 INT55801 Regulation of Positive_regulation of Got1 3 0.08 2.08 0.33 99.90
30 INT7909 Positive_regulation of Positive_regulation of Got1 8 0.49 6.44 3.06 99.90
31 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 99.88
32 INT15744 Localization of GYPA 12 0.64 7.19 2.61 99.88
33 INT326597 Negative_regulation of Localization of GYPA 1 0.16 1.51 0.1 99.88
34 INT203873 Phosphorylation of NAT2 2 0.81 0.69 0 99.88
35 INT140288 Localization of Pon1 4 0.78 6.15 1.15 99.84
36 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.84
37 INT158148 Positive_regulation of Gene_expression of Gc 2 0.36 1.89 0.23 99.84
38 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 99.84
39 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 99.84
40 INT5743 Localization of NA 104 0.59 14.35 35.29 99.84
41 INT8106 Gene_expression of GGT1 31 0.75 18.65 6.1 99.84
42 INT7991 Gene_expression of SPANXA1 8 0.67 3.41 1.2 99.84
43 INT252736 Transcription of ELANE 2 0.25 0.94 0.39 99.84
44 INT227416 Positive_regulation of DLAT 4 0.45 17.02 1.11 99.80
45 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 99.80
46 INT135458 Negative_regulation of Negative_regulation of Cyp1a2 1 0.35 0.36 0.09 99.80
47 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.76
48 INT79140 Binding of HCC 36 0.31 46.96 1.87 99.76
49 INT155838 Binding of GGT1 7 0.47 13.27 1.11 99.76
50 INT31226 Localization of PPY 20 0.78 9.93 6.8 99.74
51 INT124218 Gene_expression of Pon1 9 0.75 19.55 1.19 99.68
52 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 99.68
53 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 99.68
54 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 99.66
55 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42 99.64
56 INT355863 Binding of EXT1 1 0.20 6.43 0.05 99.64
57 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 99.64
58 INT252728 Gene_expression of FBRS 5 0.33 2.39 0.7 99.62
59 INT111822 Binding of Krt8 6 0.34 4.61 0.39 99.60
60 INT283508 Negative_regulation of Negative_regulation of DLAT 1 0.28 1.87 0.19 99.60
61 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 99.60
62 INT179698 Positive_regulation of CYP4F3 5 0.54 3.86 0.91 99.60
63 INT225694 Negative_regulation of Gene_expression of Entpd2 1 0.27 0.97 0.37 99.60
64 INT214860 Binding of GYPC 10 0.36 11.18 0.74 99.60
65 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 99.60
66 INT303837 Negative_regulation of Pon1 4 0.57 11.08 0.71 99.56
67 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 99.56
68 INT79693 Regulation of Il4 30 0.51 21.96 8.6 99.56
69 INT79835 Regulation of Il10 28 0.61 21.22 11.29 99.56
70 INT252721 Binding of NAFLD2 3 0.03 5.36 0.23 99.56
71 INT12099 Localization of GOT1 2 0.35 2.54 0.72 99.56
72 INT9664 Binding of LBP 127 0.48 94.9 63.42 99.56
73 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.52
74 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 99.52
75 INT59464 Regulation of ISYNA1 21 0.43 12.15 4.63 99.52
76 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 99.52
77 INT15819 Negative_regulation of RBP1 4 0.56 2.58 0.83 99.52
78 INT232831 Binding of Krt18 7 0.39 4.61 0.21 99.48
79 INT245844 Gene_expression of Tir1 16 0.58 24.82 1.11 99.48
80 INT9110 Binding of PAH 32 0.41 42.1 3.1 99.48
81 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 99.48
82 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 99.48
83 INT14823 Gene_expression of MET 103 0.75 51.92 32.48 99.46
84 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 99.46
85 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 99.46
86 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99 99.46
87 INT78669 Negative_regulation of CYP2C18 2 0.33 1.45 0.79 99.44
88 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 99.44
89 INT213689 Binding of HPYR1 4 0.29 4.69 0.41 99.44
90 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.42
91 INT199308 Gene_expression of Krt8 37 0.75 23.17 1.06 99.40
92 INT232826 Gene_expression of Krt18 26 0.68 14.24 0.48 99.40
93 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 99.40
94 INT301600 Positive_regulation of CYP4F2 1 0.47 0.28 0.13 99.40
95 INT57561 Regulation of Gene_expression of GLA 2 0.60 0.49 0.13 99.40
96 INT63820 Gene_expression of Mmp7 14 0.77 10.37 3.44 99.36
97 INT164920 Gene_expression of IL33 22 0.76 13.63 3.16 99.36
98 INT24845 Gene_expression of Gnptg 9 0.48 11.42 0.8 99.36
99 INT182666 Negative_regulation of DLAT 2 0.38 9.01 1.16 99.34
100 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 99.32
101 INT308953 Binding of Gpr18 1 0.41 0.67 0.41 99.32
102 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 99.30
103 INT215517 Gene_expression of Entpd2 3 0.36 3.91 3.63 99.28
104 INT252720 Negative_regulation of IREB2 1 0.06 0.82 0.05 99.26
105 INT252724 Negative_regulation of Gene_expression of IREB2 1 0.06 0.89 0.05 99.26
106 INT312778 Positive_regulation of Gene_expression of Pon1 1 0.67 2.37 0.31 99.24
107 INT83479 Gene_expression of KRT18 30 0.65 27.29 1 99.24
108 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.24
109 INT227413 Gene_expression of DLAT 12 0.44 13.21 1.36 99.22
110 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 99.20
111 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07 99.20
112 INT188396 Positive_regulation of Positive_regulation of GOPC 13 0.42 1.78 1.21 99.20
113 INT117031 Binding of Samsn1 6 0.21 6.82 0.76 99.18
114 INT164587 Gene_expression of MCL1 94 0.75 124.05 5.39 99.16
115 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 99.16
116 INT108172 Positive_regulation of Gene_expression of Abcb1b 5 0.67 1.64 1.76 99.16
117 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.12
118 INT232811 Regulation of Mocos 1 0.29 0.81 0.04 99.12
119 INT349463 Negative_regulation of Gene_expression of UGT1A1 1 0.22 1.05 0 99.12
120 INT312786 Positive_regulation of Pltp 1 0.26 4.76 0.06 99.08
121 INT122041 Binding of Ppara 308 0.48 189.17 51.48 99.08
122 INT117019 Binding of olt 1 0.13 1.19 0.17 99.06
123 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 99.04
124 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 99.02
125 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 99.02
126 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8 99.00
127 INT147793 Localization of COPD 70 0.64 89.01 7.3 98.96
128 INT252699 Gene_expression of IREB2 1 0.11 1.79 0.05 98.94
129 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 98.92
130 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 98.84
131 INT112003 Localization of ROS1 94 0.73 66.32 12.16 98.80
132 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 98.80
133 INT186862 Regulation of Pon1 5 0.60 6.15 0.51 98.80
134 INT64563 Gene_expression of UGT1A1 27 0.75 3.31 13.43 98.80
135 INT44942 Positive_regulation of Localization of HSD11B1 5 0.49 4.18 0.31 98.80
136 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 98.78
137 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 98.76
138 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88 98.76
139 INT201196 Negative_regulation of Gene_expression of PAH 2 0.30 3.11 0.19 98.76
140 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 98.76
141 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 98.76
142 INT116725 Positive_regulation of CETP 19 0.49 16.33 0.36 98.72
143 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 98.72
144 INT252 Localization of GH1 529 0.80 227.4 122.05 98.72
145 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 98.72
146 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11 98.72
147 INT155216 Negative_regulation of Gene_expression of CYP3A4 9 0.56 3.81 2.71 98.68
148 INT60779 Negative_regulation of CYP3A 63 0.59 8.38 21.27 98.68
149 INT36329 Negative_regulation of GGCX 2 0.12 1.9 0.26 98.68
150 INT4133 Binding of Npc1 14 0.47 8.24 0.33 98.68
151 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 98.64
152 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 98.64
153 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 98.64
154 INT108173 Gene_expression of Abcb1b 14 0.75 8.61 4.26 98.64
155 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05 98.64
156 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 98.64
157 INT47540 Binding of Cp 20 0.41 15.54 7.01 98.58
158 INT3442 Negative_regulation of Lcat 2 0.42 4.36 0.12 98.56
159 INT9324 Negative_regulation of Gene_expression of Igf2 6 0.50 5.12 1.2 98.56
160 INT9335 Gene_expression of Igf2 18 0.72 12.76 2.78 98.56
161 INT127432 Gene_expression of Nup62 20 0.71 11.01 0.71 98.56
162 INT167842 Positive_regulation of EXT1 5 0.50 2.88 0 98.56
163 INT81796 Binding of AGRP 62 0.36 37.19 5.3 98.56
164 INT25709 Negative_regulation of Igf2 11 0.56 9.38 3.76 98.56
165 INT352803 Positive_regulation of FGF21 1 0.66 18.41 0.14 98.52
166 INT352805 Positive_regulation of Gene_expression of FGF21 1 0.47 4.89 0 98.52
167 INT10980 Gene_expression of GYPA 40 0.78 15.32 5.51 98.44
168 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 98.44
169 INT8667 Localization of HSD11B1 22 0.73 22.74 1.25 98.44
170 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08 98.40
171 INT14902 Negative_regulation of XDH 38 0.55 24.19 2.86 98.40
172 INT115374 Positive_regulation of Gene_expression of Cyp2e1 6 0.67 4.36 1.27 98.40
173 INT179373 Localization of XDH 3 0.20 1.97 0.54 98.40
174 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 98.38
175 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 98.36
176 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 98.32
177 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 98.32
178 INT86340 Positive_regulation of Casp14 6 0.45 1.65 3.41 98.32
179 INT143983 Gene_expression of Lifr 9 0.47 6.26 1.79 98.32
180 INT216455 Negative_regulation of Gene_expression of Lifr 1 0.36 1.71 0.2 98.32
181 INT180368 Localization of AMELX 1 0.06 1.9 0.03 98.30
182 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 98.28
183 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 98.28
184 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55 98.26
185 INT326600 Negative_regulation of Gene_expression of DRD2 1 0.53 0.35 0.23 98.26
186 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 98.24
187 INT10821 Positive_regulation of Abo 32 0.67 9.43 7.65 98.24
188 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 98.24
189 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 98.20
190 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68 98.20
191 INT42581 Regulation of Gene_expression of ELANE 11 0.38 9.25 3.38 98.20
192 INT157416 Positive_regulation of Samsn1 6 0.53 4.28 0.33 98.20
193 INT182667 Binding of DLAT 11 0.31 40.75 2.8 98.16
194 INT179697 Regulation of CYP4F3 4 0.47 4.36 0.83 98.16
195 INT2064 Positive_regulation of BTG3 29 0.49 25.58 15.37 98.14
196 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 98.12
197 INT139321 Positive_regulation of Saa2 5 0.48 6.64 0.54 98.12
198 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 98.10
199 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 98.10
200 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 98.10
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