D:Liver Failure

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Disease Term
Synonyms HEPATIC FAILURE
Documents 968
Hot Single Events 200
Hot Interactions 12

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Liver Failure. They are ordered first by their relevance to Liver Failure and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT319963 Binding of IGFALS and Vcan 1 0.03 2.99 0.13 99.00
2 INT349586 Aap Regulation of Gene_expression of Ros1 1 0.03 0.56 1.17 98.86
3 INT39870 Odc1 Negative_regulation of Tk1 1 0.36 0.8 0.46 98.62
4 INT154337 Ppa1 Regulation of Aap 1 0.15 0.45 0.07 96.40
5 INT349588 Aap Positive_regulation of Gene_expression of Ros1 1 0.06 0.73 1.85 91.60
6 INT326049 Csf2 Negative_regulation of Epo 1 0.46 0.25 0 89.24
7 INT339675 CSF2 Positive_regulation of Localization of FUT1 1 0.01 0.42 0 86.72
8 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 86.04
9 INT349576 Binding of Ugt2b and Sult1a1 1 0.00 0.45 1.03 85.92
10 INT116124 Binding of AFP and HCC 2 0.20 1.72 0.15 85.20
11 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13 84.92
12 INT251701 Bche Regulation of Gene_expression of Acot1 1 0.03 0.25 0.03 80.48
13 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68 74.72
14 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87 73.76
15 INT251706 Chat Regulation of Gene_expression of Acot1 1 0.06 1.64 0.85 73.76
16 INT251708 Chat Regulation of Acot1 1 0.03 1.64 0.84 73.36
17 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24 71.16
18 INT337572 TREM1 Regulation of CRP 1 0.05 0.99 0.07 67.52
19 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 60.88
20 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52 60.88
21 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 60.88
22 INT278242 MSC Regulation of Gene_expression of Cd36 1 0.08 1.17 0 60.24
23 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98 54.04
24 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98 54.04
25 INT87808 Binding of Gpt and HCC 3 0.04 5.09 0.07 53.84
26 INT220289 MARS Regulation of CEBPZ 1 0.02 0.93 0.11 44.64
27 INT326047 Csf2 Regulation of Epo 1 0.29 0.22 0 43.12
28 INT301655 Irs1 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08 38.68
29 INT301649 Irs1 Negative_regulation of Transcription of G6pc 1 0.05 0.65 0.08 38.68
30 INT301641 Irs2 Negative_regulation of Transcription of Pck1 1 0.03 0.65 0.08 38.28
31 INT301628 Irs2 Negative_regulation of Transcription of G6pc 1 0.04 0.65 0.08 38.28
32 INT251702 Fig4 Regulation of Positive_regulation of Ache 1 0.07 0.42 0 36.72
33 INT323502 Ghrl Positive_regulation of Localization of Ins1 1 0.15 1.58 0.33 36.68
34 INT316112 Binding of S100B and SAE1 1 0.05 1.5 0.08 35.92
35 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84 34.52
36 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84 34.52
37 INT301619 Positive_regulation of Irs1 Positive_regulation of Gene_expression of Srebf1 1 0.10 0.67 0.08 33.60
38 INT301082 Binding of BCS1L and TARM1 1 0.17 1.21 0 33.00
39 INT278229 MSC Positive_regulation of Gene_expression of ALB 1 0.06 0.3 0 31.96
40 INT286070 Igf1 Regulation of Regulation of Ins1 1 0.10 1.7 0.2 31.28
41 INT301646 Srebf1 Negative_regulation of Gene_expression of Irs2 1 0.08 0.62 0.08 30.88
42 INT286071 Igf1 Regulation of Ins1 1 0.10 1.69 0.2 30.32
43 INT294894 CYP3A4 Negative_regulation of CYP2C19 1 0.08 0.13 0 25.52
44 INT294895 CYP3A4 Negative_regulation of CYP2C9 1 0.09 0.13 0 25.52
45 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 25.00
46 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43 15.20
47 INT323491 Olfr781 Positive_regulation of Localization of Ins1 1 0.01 0.87 0.4 14.48
48 INT301631 Gene_expression of Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.09 0.72 0.08 13.64
49 INT301659 Gene_expression of Mapk8 Positive_regulation of Positive_regulation of Srebf1 1 0.33 0.8 0.08 13.64
50 INT191816 Binding of ETFA and TGM2 1 0.01 0.66 0 11.20
51 INT301647 Negative_regulation of Mapk8 Positive_regulation of Irs1 1 0.08 0.83 0.04 5.52
52 INT301626 Mapk8 Positive_regulation of Irs1 1 0.09 0.83 0.04 5.52
53 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
54 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
55 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
56 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
57 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
58 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59 5.00
59 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
60 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 5.00
61 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
62 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71 5.00
63 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
64 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
65 INT349585 Aap Positive_regulation of Etf1 1 0.00 1.68 1.94 5.00
66 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
67 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31 5.00
68 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
69 INT349587 Binding of Aap and Csf2 1 0.04 0.41 1.18 5.00
70 INT349590 Aap Positive_regulation of Cytl1 1 0.13 1.31 1.15 5.00
71 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 5.00
72 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09 5.00
73 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08 5.00
74 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
75 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
76 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
77 INT349592 GTF2H5 Negative_regulation of Cyp2c22 1 0.00 0.64 0.98 5.00
78 INT275097 Twist1 Regulation of Ltp 1 0.01 0.37 0.96 5.00
79 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88 5.00
80 INT261783 Bdnf Regulation of Gene_expression of Slc12a5 1 0.09 0 0.87 5.00
81 INT221257 Pde5a Positive_regulation of PRKG1 3 0.07 0.19 0.86 5.00
82 INT261786 Bdnf Negative_regulation of Slc12a5 1 0.14 0.05 0.85 5.00
83 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 5.00
84 INT257222 Binding of Ltp and Pde5a 2 0.07 0.14 0.75 5.00
85 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75 5.00
86 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73 5.00
87 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
88 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7 5.00
89 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69 5.00
90 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63 5.00
91 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 5.00
92 INT275063 CA2 Positive_regulation of Positive_regulation of CAMK4 1 0.01 0 0.59 5.00
93 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55 5.00
94 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54 5.00
95 INT355878 Il17a Regulation of Eae1 1 0.06 1.52 0.54 5.00
96 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54 5.00
97 INT182021 Binding of TNF and Il6 2 0.04 0.74 0.53 5.00
98 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48 5.00
99 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48 5.00
100 INT300957 Binding of IL13 and Il4 1 0.01 0.58 0.48 5.00
101 INT300959 Il4 Negative_regulation of TNF 1 0.03 0.37 0.48 5.00
102 INT300955 Il4 Negative_regulation of Il6 1 0.03 0.37 0.48 5.00
103 INT238639 Cd86 Negative_regulation of Negative_regulation of Bcl2 1 0.01 0.97 0.46 5.00
104 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45 5.00
105 INT261782 Bdnf Positive_regulation of Gene_expression of Slc12a5 1 0.18 0 0.44 5.00
106 INT275100 Pde4a Negative_regulation of RTP3 1 0.00 0.51 0.42 5.00
107 INT275087 Pde2a Negative_regulation of stm 1 0.01 0.51 0.42 5.00
108 INT275089 Pde4a Negative_regulation of stm 1 0.02 0.51 0.42 5.00
109 INT275104 Pde2a Negative_regulation of RTP3 1 0.00 0.51 0.42 5.00
110 INT261790 SHC1 Positive_regulation of Slc12a5 1 0.02 0.06 0.41 5.00
111 INT182100 Positive_regulation of Binding of TNF and Il6 1 0.03 0.66 0.41 5.00
112 INT182479 Binding of Cxcl16 and Cxcr6 1 0.33 0.43 0.4 5.00
113 INT275099 Pde9a Negative_regulation of RTP3 1 0.00 0.51 0.39 5.00
114 INT275093 Pde9a Negative_regulation of stm 1 0.00 0.51 0.39 5.00
115 INT261788 Bdnf Regulation of Slc12a5 1 0.10 0.07 0.38 5.00
116 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36 5.00
117 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35 5.00
118 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35 5.00
119 INT275096 Pde9a Regulation of Ltp 1 0.00 0.11 0.35 5.00
120 INT275098 Pde9a Regulation of RTP3 1 0.00 0.11 0.35 5.00
121 INT275094 Pde5a Regulation of Ltp 1 0.05 0 0.35 5.00
122 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 5.00
123 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34 5.00
124 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 5.00
125 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
126 INT343569 Negative_regulation of Synm Positive_regulation of Gpt 1 0.01 0.96 0.29 5.00
127 INT343571 Synm Positive_regulation of ALPP 1 0.01 1.28 0.28 5.00
128 INT343570 Synm Positive_regulation of Gpt 1 0.01 1.28 0.28 5.00
129 INT343573 Synm Positive_regulation of SLC17A5 1 0.17 1.28 0.28 5.00
130 INT301666 Binding of CYP4F2 and Ltb4r1 1 0.02 0.57 0.28 5.00
131 INT301668 Ltb4r1 Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 5.00
132 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27 5.00
133 INT214658 Fabp1 Regulation of Gene_expression of Il6 1 0.02 0.59 0.27 5.00
134 INT301670 Binding of CYP4F2 and Cyp4f18 1 0.02 1.04 0.27 5.00
135 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26 5.00
136 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26 5.00
137 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
138 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
139 INT280008 Binding of IFNA1 and PAEP 2 0.08 1.29 0.25 5.00
140 INT300958 IL1B Positive_regulation of Il6 1 0.04 0.25 0.25 5.00
141 INT343931 Hapln1 Negative_regulation of Tlr4 1 0.12 0.42 0.25 5.00
142 INT275092 Twist1 Regulation of stm 1 0.00 0 0.25 5.00
143 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23 5.00
144 INT258398 Binding of IL6R and JAK1 1 0.01 0.75 0.23 5.00
145 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22 5.00
146 INT283520 Binding of DLAT and Pain1 1 0.27 0.65 0.22 5.00
147 INT355877 Binding of Hand1 and Il4 1 0.14 0.25 0.22 5.00
148 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
149 INT331602 Binding of SSRP1 and Tlr4 1 0.03 0.9 0.21 5.00
150 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 5.00
151 INT129594 St13 Positive_regulation of Positive_regulation of Tnf 1 0.26 0.85 0.21 5.00
152 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2 5.00
153 INT261787 Positive_regulation of Bdnf Positive_regulation of Fig4 1 0.02 0.77 0.2 5.00
154 INT261784 Positive_regulation of Bdnf Positive_regulation of Slc12a5 1 0.15 0.77 0.2 5.00
155 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19 5.00
156 INT301083 Binding of BCS1L and MYH7 1 0.36 1.53 0.19 5.00
157 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19 5.00
158 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19 5.00
159 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
160 INT301615 Binding of Cyp2e1 and Samsn1 1 0.02 2.42 0.18 5.00
161 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18 5.00
162 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18 5.00
163 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
164 INT214380 Binding of IL1A and PRTN3 1 0.00 0.94 0.18 5.00
165 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18 5.00
166 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18 5.00
167 INT323494 Ghrl Regulation of Ins1 1 0.16 2.12 0.17 5.00
168 INT326048 Gtf3a Positive_regulation of Positive_regulation of Csf2 1 0.04 0.5 0.16 5.00
169 INT331600 Il18 Regulation of IFN1@ 1 0.00 1.05 0.16 5.00
170 INT331601 Il10 Regulation of IFN1@ 1 0.00 1.05 0.16 5.00
171 INT129592 St13 Positive_regulation of Protein_catabolism of Stat3 1 0.26 0.84 0.16 5.00
172 INT129593 St13 Positive_regulation of Positive_regulation of Stat3 1 0.28 0.84 0.16 5.00
173 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16 5.00
174 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16 5.00
175 INT182480 Binding of Cd1d1 and Cxcr6 1 0.27 0.25 0.15 5.00
176 INT334590 IRF6 Positive_regulation of Localization of Ptger2 1 0.00 0 0.15 5.00
177 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 5.00
178 INT267799 Binding of RLS and ADHD1 1 0.00 4.84 0.14 5.00
179 INT355867 Binding of Afp and HCC 1 0.01 2.25 0.14 5.00
180 INT301638 Ppara Regulation of Slc27a2 1 0.30 0.29 0.14 5.00
181 INT182478 Binding of Akt1 and Cx3cr1 1 0.11 0.12 0.13 5.00
182 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
183 INT182477 Binding of Akt1 and Cxcr4 1 0.10 0.12 0.13 5.00
184 INT182484 Binding of Akt1 and Cxcr4 Positive_regulation of Akt1 1 0.06 0.12 0.13 5.00
185 INT261789 PDGFA Positive_regulation of Slc12a5 1 0.07 0.15 0.12 5.00
186 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12 5.00
187 INT182483 Cxcr6 Positive_regulation of Akt1 1 0.22 0.12 0.12 5.00
188 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12 5.00
189 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12 5.00
190 INT182886 Ros1 Positive_regulation of Mapk8 3 0.09 2.3 0.12 5.00
191 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12 5.00
192 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
193 INT301637 Positive_regulation of Ros1 Positive_regulation of Phosphorylation of Ins1 1 0.00 0.91 0.1 5.00
194 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
195 INT240903 Mapk8 Positive_regulation of Ros1 2 0.09 1.01 0.1 5.00
196 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
197 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09 5.00
198 INT301660 Ppara Regulation of Gene_expression of CYP4A11 1 0.24 0.65 0.09 5.00
199 INT301663 Ppara Regulation of CYP4A11 1 0.14 0.65 0.09 5.00
200 INT262335 Binding of Sv2a and Bri3 1 0.01 0.71 0.08 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Liver Failure. They are ordered first by their pain relevance and then by number of times they were reported in Liver Failure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT28802 Binding of F2 15 0.47 8.8 3.47 100.00
2 INT3112 Regulation of Odc1 39 0.62 4.73 13.69 100.00
3 INT51312 Positive_regulation of Gene_expression of SERPINA1 4 0.46 9.41 3.84 100.00
4 INT61423 Gene_expression of Egfl7 23 0.14 24.96 0.66 99.98
5 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.98
6 INT797 Regulation of Penk 812 0.62 111.13 542.24 99.92
7 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.92
8 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 99.92
9 INT245785 Negative_regulation of NDUFS4 1 0.06 1.16 0.09 99.92
10 INT70242 Localization of HCC 18 0.66 23.95 2.35 99.88
11 INT3180 Positive_regulation of PPY 39 0.63 25.57 10.15 99.84
12 INT226106 Negative_regulation of Ghrl 12 0.40 3.98 5.39 99.84
13 INT162336 Negative_regulation of Ckb 1 0.12 0.55 0.43 99.72
14 INT249057 Gene_expression of FGF14 1 0.33 3.44 0.04 99.72
15 INT276 Regulation of Ache 83 0.62 16.75 25.99 99.68
16 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84 99.68
17 INT71794 Binding of SERPINC1 17 0.39 10.5 2.64 99.68
18 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 99.66
19 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29 99.64
20 INT46357 Regulation of Gene_expression of Acot1 4 0.45 1.1 0.26 99.64
21 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 99.54
22 INT79140 Binding of HCC 36 0.31 46.96 1.87 99.54
23 INT24527 Negative_regulation of Gal 12 0.59 7.16 6.29 99.48
24 INT220295 Gene_expression of MARS 6 0.47 4.74 0.35 99.44
25 INT220294 Positive_regulation of Gene_expression of MARS 3 0.35 2.45 0.05 99.44
26 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 99.40
27 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 99.40
28 INT3074 Negative_regulation of Chkb 29 0.57 14 12.04 99.36
29 INT65071 Positive_regulation of Gene_expression of TKT 4 0.18 4.44 0.14 99.36
30 INT132411 Positive_regulation of Ghrl 25 0.69 12.05 2.59 99.36
31 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59 99.36
32 INT150853 Negative_regulation of Cxcl1 22 0.49 12.61 5.72 99.32
33 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 99.30
34 INT17566 Gene_expression of Hya 1 0.24 0.49 0.13 99.30
35 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 99.26
36 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 99.16
37 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28 99.08
38 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 99.08
39 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 99.04
40 INT65072 Gene_expression of TKT 16 0.65 17.58 3.55 98.96
41 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 98.96
42 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 98.96
43 INT227405 Localization of Pdc 4 0.32 2.87 0.15 98.92
44 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 98.88
45 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 98.88
46 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 98.88
47 INT211968 Localization of Best1 11 0.40 9.33 0.38 98.88
48 INT4735 Gene_expression of Acot1 80 0.71 13.22 26.68 98.86
49 INT45878 Gene_expression of NEU1 14 0.65 7.28 0.47 98.80
50 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 98.68
51 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 98.68
52 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 98.68
53 INT159531 Positive_regulation of Gene_expression of SLC17A5 8 0.49 9.3 0.77 98.68
54 INT11829 Negative_regulation of Odc1 54 0.59 7.03 23.03 98.62
55 INT28886 Negative_regulation of Tk1 5 0.45 1.66 0.64 98.62
56 INT249059 Binding of FGF14 1 0.20 2.3 0.13 98.56
57 INT95944 Binding of Fgf12 11 0.28 8.98 2.53 98.54
58 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37 98.52
59 INT32852 Negative_regulation of FECH 18 0.57 10.59 3.08 98.48
60 INT32052 Positive_regulation of Negative_regulation of Acot1 2 0.24 0.73 0.41 98.48
61 INT53568 Positive_regulation of Negative_regulation of FECH 1 0.47 0.78 0.05 98.48
62 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 98.36
63 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 98.36
64 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 98.28
65 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 98.24
66 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 98.20
67 INT81795 Negative_regulation of AGRP 23 0.41 10.93 0.87 98.14
68 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 98.08
69 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 98.04
70 INT74648 Phosphorylation of Hgf 1 0.63 1.81 0.28 97.76
71 INT74647 Regulation of Hgf 3 0.45 3.67 0.55 97.76
72 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 97.64
73 INT1354 Negative_regulation of Acot1 87 0.43 15.01 36.44 97.60
74 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 97.60
75 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 97.60
76 INT934 Regulation of Gtf3a 25 0.35 11.35 6.34 97.56
77 INT78786 Regulation of Ptpre 1 0.34 0.1 0.06 97.56
78 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 97.52
79 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 97.38
80 INT192426 Gene_expression of TARM1 3 0.33 1.98 0 97.36
81 INT31403 Positive_regulation of AFM 3 0.29 5.57 1.38 97.12
82 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 97.10
83 INT159946 Gene_expression of Mat1a 23 0.77 15.33 7.49 97.08
84 INT167858 Regulation of Gene_expression of Mat1a 3 0.61 2.97 2.33 97.08
85 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 97.04
86 INT6335 Binding of TSPO 39 0.44 10.88 7.66 97.00
87 INT108919 Positive_regulation of Mapk9 9 0.34 3.55 4.74 97.00
88 INT108921 Negative_regulation of Positive_regulation of Mapk9 3 0.25 1.8 1.99 97.00
89 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 96.92
90 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 96.68
91 INT6485 Positive_regulation of Ceacam1 5 0.24 3.23 0.39 96.68
92 INT174190 Regulation of Gene_expression of TKT 4 0.43 2.99 0.03 96.68
93 INT196191 Binding of Mrgpre 7 0.14 5.84 0.25 96.64
94 INT3174 Negative_regulation of Ptger2 43 0.38 20.95 13.43 96.60
95 INT140054 Negative_regulation of Mapk9 3 0.25 1.9 1.05 96.56
96 INT134901 Negative_regulation of Fah 1 0.20 0.87 0.1 96.48
97 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28 96.44
98 INT16720 Negative_regulation of Xdh 35 0.59 14 6.67 96.44
99 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 96.40
100 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.28
101 INT163929 Negative_regulation of Fabp1 3 0.32 1.69 0.26 96.28
102 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 96.24
103 INT227401 Gene_expression of Nup210 2 0.51 1.26 0.12 96.08
104 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 96.04
105 INT11747 Positive_regulation of IL2RA 22 0.67 16.55 6.95 96.04
106 INT84946 Gene_expression of GGT5 5 0.06 2.31 0.31 96.00
107 INT109097 Positive_regulation of Gene_expression of GGT5 2 0.05 2.19 0.24 96.00
108 INT47451 Positive_regulation of Positive_regulation of ras 18 0.35 10.07 4.6 95.88
109 INT3491 Negative_regulation of CPT2 8 0.57 4.32 0.62 95.72
110 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 95.70
111 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 95.56
112 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 95.44
113 INT2139 Negative_regulation of Cea 55 0.43 43.59 9.14 95.44
114 INT133354 Regulation of Chkb 9 0.60 4.35 3.15 95.40
115 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 95.28
116 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 95.20
117 INT63505 Negative_regulation of F2 18 0.57 7.4 2.2 94.96
118 INT245844 Gene_expression of Tir1 16 0.58 24.82 1.11 94.84
119 INT245850 Positive_regulation of Gene_expression of Tir1 1 0.37 1.77 0 94.84
120 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36 94.76
121 INT7678 Localization of Alb 142 0.81 80.93 22.49 94.76
122 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 94.76
123 INT20201 Positive_regulation of Fgf12 8 0.43 15.13 0.98 94.72
124 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 94.72
125 INT200523 Regulation of F7 2 0.01 1.82 0.38 94.56
126 INT212534 Transcription of Fgf12 1 0.39 1.37 0 94.40
127 INT2432 Positive_regulation of Cp 41 0.67 31.1 16.68 94.28
128 INT162 Regulation of Prl 794 0.62 165.01 322.24 94.16
129 INT55792 Regulation of Negative_regulation of Bche 11 0.57 1.78 3.21 94.16
130 INT214649 Localization of Fabp1 1 0.44 6.06 2.19 94.12
131 INT22907 Positive_regulation of Ggt1 33 0.67 17.82 5.28 94.12
132 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 94.08
133 INT138506 Negative_regulation of F3 2 0.04 1.23 0.2 94.08
134 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41 94.04
135 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37 93.96
136 INT114311 Negative_regulation of Gene_expression of Gpt 33 0.38 17.83 4.94 93.44
137 INT39587 Gene_expression of CP 42 0.65 31.48 11.87 93.24
138 INT28122 Gene_expression of MSC 111 0.58 26.83 6.57 93.20
139 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 93.12
140 INT169352 Negative_regulation of Timp3 10 0.58 6.94 1.92 93.12
141 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 93.12
142 INT224352 Positive_regulation of Protein_catabolism of SPTB 1 0.01 1.12 0.14 93.08
143 INT16870 Negative_regulation of Gsr 27 0.59 10.28 11.81 93.00
144 INT38834 Positive_regulation of Positive_regulation of PPY 2 0.42 4.18 0.61 92.92
145 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 92.84
146 INT207175 Transcription of VAC14 1 0.43 1.58 0 92.80
147 INT85798 Positive_regulation of Map3k5 3 0.46 1.2 0.66 92.80
148 INT7561 Positive_regulation of gr 70 0.57 31.92 20.22 92.76
149 INT55091 Positive_regulation of Mgst1 35 0.69 10.77 6.88 92.76
150 INT114330 Binding of MPZ 21 0.32 25.58 2.14 92.72
151 INT224351 Protein_catabolism of SPTB 1 0.01 1.12 0.14 92.60
152 INT78785 Binding of Ptpre 1 0.23 0.09 0.08 92.60
153 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 92.40
154 INT339687 Positive_regulation of ARHGEF1 1 0.03 0.44 0 92.40
155 INT339689 Positive_regulation of Positive_regulation of ARHGEF1 1 0.03 0.44 0 92.40
156 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 92.36
157 INT60685 Positive_regulation of Gene_expression of Epo 21 0.53 15.86 1.25 92.28
158 INT131286 Binding of Egfr 26 0.44 13.58 0.78 92.28
159 INT99298 Positive_regulation of ITGA3 6 0.06 2.94 1.54 92.24
160 INT105130 Positive_regulation of Arigg3 2 0.02 2.11 0.44 92.24
161 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 92.16
162 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 92.00
163 INT112991 Positive_regulation of Gene_expression of PPY 7 0.29 6.26 0.99 92.00
164 INT19044 Positive_regulation of GGT5 10 0.65 7.7 1.11 91.92
165 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 91.84
166 INT11945 Regulation of Chat 38 0.62 7.75 14.97 91.68
167 INT158837 Binding of POLG 4 0.37 4.69 0.44 91.60
168 INT99899 Regulation of Mmp23 3 0.17 2.31 0.69 91.56
169 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 91.48
170 INT53201 Negative_regulation of gr 35 0.50 17.76 10.62 91.48
171 INT31599 Negative_regulation of Mgst1 14 0.59 5.35 1.72 91.48
172 INT169349 Regulation of Adam17 1 0.37 0.97 0.13 91.44
173 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 91.36
174 INT227411 Negative_regulation of Positive_regulation of HCC 1 0.02 1.35 0.11 91.36
175 INT145953 Positive_regulation of Positive_regulation of F8 5 0.29 4.85 1.17 91.24
176 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89 91.24
177 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 91.20
178 INT11807 Gene_expression of Il2 266 0.78 112 64.97 91.12
179 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63 91.12
180 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96 91.12
181 INT28191 Positive_regulation of Positive_regulation of CYP2E1 5 0.49 3.5 2.25 90.92
182 INT118272 Positive_regulation of USP33 1 0.52 0.34 0.1 90.84
183 INT79096 Binding of Cyp2e1 12 0.48 4.41 3.8 90.52
184 INT69564 Binding of Cyp3a23/3a1 11 0.34 4.67 3.2 90.52
185 INT43290 Binding of Cyp3a62 5 0.37 1.33 1.23 90.52
186 INT103370 Binding of CREB3L4 1 0.36 0.6 0.42 90.52
187 INT20336 Positive_regulation of CYP2E1 48 0.70 19.26 15.66 90.44
188 INT169353 Negative_regulation of Areg 1 0.24 1.23 0.29 90.40
189 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 90.36
190 INT68406 Localization of MLRG 2 0.70 1.71 0.93 90.24
191 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 90.04
192 INT46109 Binding of SERPINF2 6 0.37 1.08 2.06 89.92
193 INT9385 Localization of LDHA 74 0.81 31.67 10.5 89.76
194 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 89.52
195 INT10285 Binding of ADRA1D 102 0.47 25.82 31.11 89.52
196 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 89.36
197 INT87819 Localization of CD34 21 0.81 7.69 0.47 89.36
198 INT45597 Negative_regulation of Epo 22 0.59 12.47 2.35 89.24
199 INT193281 Binding of CAP1 7 0.07 4.57 3.53 89.08
200 INT39469 Negative_regulation of Alb 21 0.41 13.33 2.68 89.04
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