D:Low Vision

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Disease Term
Synonyms Diminished Vision, Reduced Vision, SUBNORMAL VISION, Vision Diminished, Vision Reduced, Vision Subnormal
Documents 107
Hot Single Events 7
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Low Vision. They are ordered first by their relevance to Low Vision and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT242847 Binding of CDB2 and TGFBI 1 0.17 0.56 0 43.20
2 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22 16.44
3 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22 14.48
4 INT175909 Binding of ROS1 and CNBP 1 0.01 1.78 0.19 5.00
5 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19 5.00
6 INT267117 Lmx1b Regulation of Col7a1 1 0.02 1.29 0 5.00
7 INT225969 Binding of Aqp4 and Nefl 1 0.07 0.3 0 5.00
8 INT267115 Lmx1b Regulation of Gene_expression of Col4a1 1 0.09 1.37 0 5.00
9 INT267116 Binding of Lmx1b and Nps 1 0.30 1.95 0 5.00
10 INT267119 Lmx1b Regulation of Regulation of Col4a1 1 0.09 0.67 0 5.00
11 INT267118 Lmx1b Regulation of Regulation of Col7a1 1 0.06 0.47 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Low Vision. They are ordered first by their pain relevance and then by number of times they were reported in Low Vision. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 97.28
2 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 91.96
3 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 90.08
4 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 88.92
5 INT17182 Binding of Cea 25 0.48 14.98 4.16 87.40
6 INT256900 Gene_expression of TNMD 19 0.68 7.36 0.64 81.48
7 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 80.08
8 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 79.52
9 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59 79.20
10 INT188967 Negative_regulation of Binding of AMBP 2 0.03 2.7 0.39 79.20
11 INT82918 Binding of AMBP 23 0.39 23.31 1.71 77.72
12 INT256902 Positive_regulation of TNMD 3 0.44 5.27 0.13 74.88
13 INT346642 Positive_regulation of Positive_regulation of TNMD 1 0.44 1.28 0 74.88
14 INT242851 Transcription of TGFBI 2 0.43 1.67 0.18 70.60
15 INT273160 Binding of TNMD 4 0.42 1.72 0 69.96
16 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 69.64
17 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 69.64
18 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 53.92
19 INT126322 Negative_regulation of TGFBI 4 0.41 2.12 1.63 50.12
20 INT242853 Binding of TGFBI 10 0.42 1.38 0.07 40.84
21 INT260525 Gene_expression of AMD1 25 0.66 24.58 1.32 38.96
22 INT269749 Transcription of AMD1 1 0.59 1.04 0.05 35.32
23 INT175919 Negative_regulation of Positive_regulation of FGF2 1 0.22 0.96 0.22 34.72
24 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 32.64
25 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36 32.64
26 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17 32.64
27 INT243224 Regulation of Plxna2 2 0.13 1.58 0 30.24
28 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 23.72
29 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 23.60
30 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3 23.60
31 INT321844 Positive_regulation of Krt13 1 0.01 0.15 0.07 20.24
32 INT321845 Gene_expression of Krt12 1 0.31 1 0.35 19.16
33 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 16.32
34 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 15.44
35 INT50255 Regulation of Cd4 39 0.49 29.73 6.77 13.12
36 INT321846 Gene_expression of Krt13 1 0.02 0.21 0.08 8.72
37 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 6.36
38 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
39 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
40 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
41 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
42 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
43 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
44 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
45 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 5.00
46 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
47 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
48 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
49 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
50 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
51 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
52 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
53 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 5.00
54 INT47741 Negative_regulation of Flvcr2 43 0.51 5.72 23.37 5.00
55 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
56 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
57 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 5.00
58 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
59 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
60 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
61 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
62 INT73641 Regulation of Lep 45 0.62 26.2 12.59 5.00
63 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06 5.00
64 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
65 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 5.00
66 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 5.00
67 INT58449 Binding of Mthfd1 47 0.47 22.02 10.29 5.00
68 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 5.00
69 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 5.00
70 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51 5.00
71 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 5.00
72 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 5.00
73 INT69441 Regulation of Gene_expression of ROS1 38 0.50 26.78 6.78 5.00
74 INT60700 Gene_expression of Itgax 93 0.71 51.89 6.57 5.00
75 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27 5.00
76 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 5.00
77 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16 5.00
78 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 5.00
79 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67 5.00
80 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
81 INT123422 Gene_expression of Lmx1b 18 0.78 6.93 5.17 5.00
82 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72 5.00
83 INT67144 Gene_expression of Cd44 17 0.76 8.94 4.48 5.00
84 INT188588 Localization of Mthfd1 20 0.49 9.19 4.37 5.00
85 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36 5.00
86 INT143337 Binding of Aqp4 30 0.40 23.73 4.24 5.00
87 INT20230 Negative_regulation of Positive_regulation of Alb 15 0.56 12.44 4.11 5.00
88 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79 5.00
89 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77 5.00
90 INT225965 Localization of Aqp4 26 0.81 18.85 3.75 5.00
91 INT157805 Negative_regulation of Gene_expression of Col7a1 22 0.34 12.85 3.51 5.00
92 INT139366 Gene_expression of PROM1 98 0.77 67.84 3.39 5.00
93 INT69990 Negative_regulation of Nefl 11 0.59 2.82 3.38 5.00
94 INT2117 Regulation of VSX1 15 0.30 3.38 3.38 5.00
95 INT148892 Binding of HPS1 13 0.37 19.21 3.35 5.00
96 INT93915 Positive_regulation of Gene_expression of CD40 14 0.44 12.45 3.35 5.00
97 INT48390 Negative_regulation of Localization of CSF2 10 0.51 7.39 3.28 5.00
98 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22 5.00
99 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07 5.00
100 INT126323 Regulation of TGFBI 6 0.59 3.17 2.9 5.00
101 INT21076 Negative_regulation of Muc5ac 8 0.42 2.48 2.78 5.00
102 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 5.00
103 INT45272 Regulation of Nps 15 0.39 8.08 2.69 5.00
104 INT65258 Regulation of Gene_expression of Col7a1 17 0.55 8.26 2.57 5.00
105 INT152060 Gene_expression of VUR 75 0.67 83.83 2.34 5.00
106 INT61418 Positive_regulation of ITGAL 24 0.14 12.86 2.3 5.00
107 INT131456 Negative_regulation of MMRN1 14 0.19 9.49 2.29 5.00
108 INT92835 Gene_expression of Col4a1 22 0.49 13.5 2.27 5.00
109 INT56375 Positive_regulation of AMBP 25 0.60 21.24 2.22 5.00
110 INT170469 Gene_expression of THY1 66 0.65 11.9 2.15 5.00
111 INT144364 Negative_regulation of Lmx1b 5 0.45 3.35 2.12 5.00
112 INT20373 Localization of Cd8a 28 0.64 8.22 2.07 5.00
113 INT157816 Positive_regulation of Positive_regulation of Mthfd1 5 0.33 3.73 1.93 5.00
114 INT173116 Regulation of VCAM1 14 0.33 11.85 1.92 5.00
115 INT265449 Gene_expression of Aire 10 0.67 9.18 1.8 5.00
116 INT113676 Gene_expression of NRP1 22 0.72 10.81 1.71 5.00
117 INT80857 Negative_regulation of Cpt2 19 0.42 12.1 1.6 5.00
118 INT12890 Gene_expression of Ttr 15 0.63 7.68 1.6 5.00
119 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59 5.00
120 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52 5.00
121 INT165432 Negative_regulation of BLMH 3 0.13 1.62 1.37 5.00
122 INT65261 Regulation of Col7a1 18 0.55 8.7 1.33 5.00
123 INT265438 Gene_expression of Sprr1b 1 0.72 6.76 1.33 5.00
124 INT265444 Negative_regulation of Aire 1 0.37 5.68 1.3 5.00
125 INT204772 Negative_regulation of Gene_expression of Mthfd1 10 0.15 3.48 1.29 5.00
126 INT36500 Negative_regulation of Gene_expression of Tf 4 0.38 1.22 1.29 5.00
127 INT173208 Binding of CNBP 9 0.25 11.01 1.23 5.00
128 INT36461 Regulation of Col4a1 10 0.26 5.43 1.17 5.00
129 INT97777 Positive_regulation of CNBP 7 0.37 9.85 1.09 5.00
130 INT265440 Gene_expression of Abpe 2 0.19 10.64 1.07 5.00
131 INT56386 Positive_regulation of UBXN11 6 0.49 2.79 1.05 5.00
132 INT15726 Negative_regulation of Gene_expression of Fn1 8 0.32 5.25 1.04 5.00
133 INT17817 Binding of VUR 41 0.48 46.85 0.95 5.00
134 INT256638 Binding of Ubxn11 1 0.48 1.79 0.95 5.00
135 INT76216 Positive_regulation of Krt12 2 0.40 0.37 0.92 5.00
136 INT23913 Negative_regulation of Gene_expression of Ttr 3 0.15 2.8 0.87 5.00
137 INT47055 Gene_expression of RBP1 8 0.75 7.85 0.86 5.00
138 INT96480 Negative_regulation of Positive_regulation of Mthfd1 5 0.30 0.99 0.83 5.00
139 INT102353 Positive_regulation of HLA-DQA2 6 0.06 4.07 0.82 5.00
140 INT175914 Positive_regulation of Iph1 1 0.01 3.18 0.82 5.00
141 INT184743 Localization of BTG3 4 0.68 3.6 0.78 5.00
142 INT59175 Localization of TNMD 4 0.70 4.14 0.71 5.00
143 INT222005 Regulation of HPS1 2 0.33 3.3 0.6 5.00
144 INT267114 Positive_regulation of Lmx1b 2 0.50 0.96 0.6 5.00
145 INT202940 Binding of AMD1 13 0.41 16.43 0.56 5.00
146 INT68446 Negative_regulation of Cpt1a 5 0.38 6.5 0.56 5.00
147 INT312398 Positive_regulation of PCNT 3 0.40 0.75 0.53 5.00
148 INT265433 Positive_regulation of Sprr1b 1 0.64 3.76 0.53 5.00
149 INT174271 Binding of F3 6 0.15 6.85 0.53 5.00
150 INT265448 Positive_regulation of Gene_expression of Sprr1b 1 0.64 1.95 0.51 5.00
151 INT135541 Negative_regulation of Bak1 6 0.30 4.52 0.49 5.00
152 INT307615 Negative_regulation of Positive_regulation of CSF2 4 0.36 3.55 0.48 5.00
153 INT213967 Positive_regulation of Localization of Mthfd1 4 0.30 2.52 0.46 5.00
154 INT267113 Regulation of Gene_expression of Lmx1b 2 0.62 1.36 0.44 5.00
155 INT175915 Negative_regulation of Positive_regulation of Iph1 1 0.01 1.67 0.42 5.00
156 INT171773 Regulation of SELE 7 0.23 10.3 0.4 5.00
157 INT117313 Negative_regulation of VUR 11 0.42 12.14 0.39 5.00
158 INT39150 Gene_expression of Pcbd1 5 0.28 1.3 0.38 5.00
159 INT265446 Negative_regulation of Gene_expression of Sprr1b 1 0.40 1.9 0.36 5.00
160 INT172216 Binding of Bak1 5 0.25 8.48 0.33 5.00
161 INT308261 Positive_regulation of Localization of BTG3 1 0.39 1.61 0.32 5.00
162 INT175918 Negative_regulation of DYM 1 0.04 0.96 0.3 5.00
163 INT216800 Gene_expression of Ubxn11 2 0.67 0.66 0.3 5.00
164 INT265434 Regulation of Gene_expression of Sprr1b 1 0.42 1.04 0.29 5.00
165 INT9034 Regulation of Pcbd1 6 0.20 3.28 0.28 5.00
166 INT269748 Positive_regulation of AMD1 4 0.43 3.56 0.28 5.00
167 INT162177 Binding of EBM 12 0.32 3.34 0.27 5.00
168 INT265442 Positive_regulation of Gene_expression of Aire 1 0.43 1.32 0.27 5.00
169 INT256639 Localization of Ubxn11 1 0.65 0.71 0.27 5.00
170 INT308149 Gene_expression of Slc22a5 1 0.63 2.77 0.25 5.00
171 INT265435 Negative_regulation of Muc19 1 0.19 1.3 0.25 5.00
172 INT216808 Positive_regulation of Ubxn11 3 0.41 0.17 0.2 5.00
173 INT175916 Binding of Iph1 1 0.01 1.84 0.19 5.00
174 INT265441 Positive_regulation of Aire 3 0.43 1.65 0.19 5.00
175 INT308147 Gene_expression of Slc22a4 1 0.33 1.55 0.17 5.00
176 INT308146 Localization of Nme1 1 0.01 1.34 0.16 5.00
177 INT308140 Localization of Cpt1a 1 0.30 1.34 0.16 5.00
178 INT267112 Regulation of Lmx1b 3 0.61 2.21 0.16 5.00
179 INT144009 Negative_regulation of Hspb6 3 0.43 0.46 0.15 5.00
180 INT132294 Positive_regulation of Sptlc1 3 0.31 3.84 0.14 5.00
181 INT123184 Negative_regulation of Lamtor1 2 0.13 0.59 0.14 5.00
182 INT269750 Localization of AMD1 2 0.64 2.82 0.13 5.00
183 INT265439 Negative_regulation of Gene_expression of Aire 1 0.37 0.72 0.11 5.00
184 INT228583 Regulation of Cpt1a 4 0.40 1.42 0.11 5.00
185 INT265436 Binding of Sprr1b 1 0.34 0.74 0.1 5.00
186 INT170307 Regulation of Gene_expression of Col4a1 2 0.16 1.45 0.1 5.00
187 INT321847 Positive_regulation of Gene_expression of Krt12 1 0.19 0.37 0.1 5.00
188 INT260526 Negative_regulation of Gene_expression of AMD1 2 0.36 0.71 0.09 5.00
189 INT256636 Negative_regulation of Ubxn11 1 0.43 0.08 0.08 5.00
190 INT265445 Regulation of Sprr1b 1 0.36 0.39 0.08 5.00
191 INT308139 Negative_regulation of Slc22a4 1 0.21 0.79 0.08 5.00
192 INT58917 Negative_regulation of Zdhhc7 2 0.51 1.06 0.08 5.00
193 INT256635 Regulation of Binding of Ubxn11 1 0.24 0.17 0.08 5.00
194 INT225962 Regulation of Srr 1 0.02 0.22 0.07 5.00
195 INT216805 Regulation of Ubxn11 2 0.24 0.09 0.07 5.00
196 INT308137 Regulation of Gcdh 1 0.18 0.8 0.06 5.00
197 INT260527 Negative_regulation of AMD1 6 0.37 5 0.05 5.00
198 INT308143 Regulation of Regulation of Cpt1a 1 0.22 1.06 0.05 5.00
199 INT308142 Positive_regulation of Cpt1a 1 0.23 2.64 0.04 5.00
200 INT308145 Binding of Slc22a5 1 0.39 0.14 0 5.00
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