D:Lower Respiratory Tract Infection

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Disease Term
Synonyms Chest Cold, Chest Colds, Infection Respiratory, Infection Respiratory Tract, Infection Upper Respiratory, Infections Respiratory, Infections Respiratory Tract, INFECTIONS UPPER RESPIRATORY, Lower Respiratory Tract Infections, Lower Respiratory Tract Infectious Disease, Lower Respiratory Tract Infectious Diseases
Documents 1203
Hot Single Events 177
Hot Interactions 8

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lower Respiratory Tract Infection. They are ordered first by their relevance to Lower Respiratory Tract Infection and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT283429 Nt5e Regulation of Gene_expression of Cxcr1 1 0.00 0.22 0.2 98.72
2 INT283431 Lcn2 Regulation of Gene_expression of Cxcr1 1 0.01 0.22 0.2 98.72
3 INT336713 Binding of CDA and GNPTAB 1 0.02 0.77 0 97.96
4 INT185358 Binding of MCS and PCS 7 0.22 3.34 0.57 92.84
5 INT180718 Binding of SARS and ACE2 3 0.12 7.76 0.25 91.48
6 INT250803 Binding of SARS and MBL3P 1 0.09 1.7 0.04 91.48
7 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61 81.92
8 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6 81.92
9 INT321979 Negative_regulation of Klk1c8 Negative_regulation of Positive_regulation of Ins1 1 0.04 0.81 0.22 78.48
10 INT321980 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1 1 0.16 0.81 0.22 78.48
11 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22 74.48
12 INT170666 GOPC Regulation of ANGPTL5 1 0.06 0.32 0.04 71.92
13 INT170668 GOPC Regulation of CRP 1 0.07 0.32 0.04 70.72
14 INT224308 INSRR Regulation of VEGFA 1 0.00 1.42 0.16 65.64
15 INT180715 Binding of SARS and CLEC4M 2 0.12 2.92 0.11 62.80
16 INT250804 Binding of CCL4L1 and AP5M1 1 0.01 1.48 0.08 56.16
17 INT250801 Binding of AP5M1 and MAPKAP1 1 0.00 1.48 0.08 56.16
18 INT250802 Binding of IL6 and AP5M1 1 0.01 1.47 0.05 56.16
19 INT276137 Binding of COL19A1 and HLA-DRB1 1 0.00 0.62 0 56.08
20 INT276138 Binding of COL19A1 and HLA-E 1 0.01 0.62 0 54.24
21 INT234145 Fig4 Negative_regulation of Gene_expression of Trib3 1 0.01 0.31 0 51.04
22 INT234141 Fig4 Negative_regulation of Trib3 1 0.01 0.13 0 51.04
23 INT234144 Fig4 Negative_regulation of Transcription of Tyms 1 0.05 0.18 0 51.04
24 INT220317 Binding of CPB1 and PLEKHM1 1 0.00 0.93 0.26 43.72
25 INT220318 Binding of CPB1 and CCL2 1 0.01 0.46 0.13 43.12
26 INT338457 Binding of IGHV3-63 and C5orf43 1 0.00 1.05 0 37.52
27 INT338456 Binding of ZNF76 and IGHV3-63 1 0.00 1.04 0 37.52
28 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15 37.32
29 INT306452 Binding of MBL2 and TLR4 1 0.38 0.37 0.1 37.16
30 INT306453 MBL2 Regulation of Binding of TLR4 1 0.48 0.37 0.1 37.16
31 INT259637 Binding of Mmp12 and COPD 2 0.02 1.71 0.4 36.40
32 INT259636 Binding of Tbce and COPD 1 0.04 1 0.11 36.40
33 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24 35.92
34 INT276136 Binding of DIO2 and HLA-E 1 0.26 0 0 30.48
35 INT88773 Positive_regulation of Binding of AGT and Agtrap 1 0.01 0.88 0.05 27.84
36 INT88772 Negative_regulation of Binding of AGT and Agtrap 1 0.02 0.89 0.03 25.00
37 INT88774 Binding of AGT and Agtrap 2 0.01 2.13 0.03 25.00
38 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 22.48
39 INT312637 Negative_regulation of Binding of Musk and Dok7 1 0.42 1.03 0 20.08
40 INT312635 Binding of Musk and Dok7 1 0.47 3.41 0 20.08
41 INT178662 IFN1@ Positive_regulation of CXCL9 1 0.20 0.5 0.36 18.08
42 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 15.68
43 INT323623 Binding of Adm and Edn1 1 0.04 0.77 0.03 15.36
44 INT199734 Binding of PRB1 and REN 1 0.01 0.08 0 8.28
45 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
46 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
47 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
48 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 5.00
49 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
50 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
51 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
52 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
53 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01 5.00
54 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
55 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8 5.00
56 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
57 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26 5.00
58 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26 5.00
59 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
60 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
61 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07 5.00
62 INT185373 IRF6 Positive_regulation of Gene_expression of TLR2 1 0.08 2.96 1.04 5.00
63 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
64 INT178663 Binding of CXCR3 and TH1L 2 0.04 2.24 1.01 5.00
65 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
66 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
67 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96 5.00
68 INT168528 QRFP Regulation of FSIP1 2 0.07 1.32 0.93 5.00
69 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 5.00
70 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
71 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 5.00
72 INT232417 Binding of Mtx1 and Ifx 1 0.04 0.99 0.86 5.00
73 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 5.00
74 INT341816 Binding of CEP68 and Aia1 1 0.02 4.76 0.76 5.00
75 INT219685 Binding of MMP12 and COPD 1 0.27 5.59 0.74 5.00
76 INT275554 Binding of CXCL10 and Cxcr3 1 0.03 2.18 0.71 5.00
77 INT278827 Binding of EDN1 and EDNRB 3 0.17 2.7 0.67 5.00
78 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67 5.00
79 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66 5.00
80 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
81 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59 5.00
82 INT170835 Cftr Positive_regulation of Cftr Negative_regulation of Slc10a2 1 0.55 0.31 0.56 5.00
83 INT170833 Cftr Negative_regulation of Slc10a2 1 0.47 0.31 0.56 5.00
84 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55 5.00
85 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53 5.00
86 INT278819 EDNRA Negative_regulation of Binding of EDNRA and EDNRB 1 0.04 1.65 0.53 5.00
87 INT219253 Binding of Cd79a and Pigr 2 0.22 0.67 0.52 5.00
88 INT283434 Lcn2 Positive_regulation of Localization of IL8 1 0.07 1.33 0.51 5.00
89 INT278825 Positive_regulation of Binding of EDN1 and EDNRB 3 0.16 1.24 0.49 5.00
90 INT275549 Il10 Positive_regulation of Localization of Hand2 1 0.01 1.3 0.46 5.00
91 INT275550 Hand1 Positive_regulation of Localization of Hand2 1 0.00 1.29 0.46 5.00
92 INT302421 IFNA1 Positive_regulation of Cxcl10 1 0.02 1.8 0.45 5.00
93 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45 5.00
94 INT302422 IFNA1 Positive_regulation of Cxcl9 1 0.03 1.81 0.45 5.00
95 INT302423 Etohi5 Positive_regulation of IFNA1 1 0.00 1.77 0.44 5.00
96 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44 5.00
97 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44 5.00
98 INT186373 Il6 Positive_regulation of Gene_expression of Il17a 2 0.14 1.52 0.42 5.00
99 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 5.00
100 INT185381 TNF Regulation of TLR2 2 0.31 1.9 0.41 5.00
101 INT168533 Binding of FSIP1 and Aia1 2 0.01 1.97 0.4 5.00
102 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39 5.00
103 INT186758 Il13 Regulation of Ccl5 2 0.17 0.17 0.39 5.00
104 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39 5.00
105 INT186757 Il13 Regulation of Ccl11 2 0.21 0.17 0.39 5.00
106 INT219684 Binding of MMP12 and GOPC 1 0.09 3.11 0.38 5.00
107 INT219683 Binding of CEL and GOPC 1 0.04 3.11 0.38 5.00
108 INT186769 Dep1 Positive_regulation of Gene_expression of IgG 2 0.03 1.3 0.36 5.00
109 INT334948 IL6 Positive_regulation of IL6 Regulation of IL1RN 1 0.17 1.11 0.35 5.00
110 INT334951 IL6 Positive_regulation of Regulation of IL1RN 1 0.23 1.11 0.35 5.00
111 INT334947 IL6 Regulation of IL6 Positive_regulation of IL1RN 1 0.10 1.11 0.35 5.00
112 INT275557 Negative_regulation of Binding of CXCL10 and Cxcr3 1 0.04 1.09 0.35 5.00
113 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 5.00
114 INT334949 IL6 Regulation of Regulation of IL1RN 1 0.13 1.11 0.35 5.00
115 INT278820 EDNRA Negative_regulation of Binding of EDN1 and EDNRB 1 0.03 1.1 0.35 5.00
116 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35 5.00
117 INT334950 IL6 Regulation of IL1RN 1 0.13 1.11 0.35 5.00
118 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33 5.00
119 INT341794 Binding of SUGT1 and CEP68 1 0.00 1.1 0.33 5.00
120 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33 5.00
121 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32 5.00
122 INT186345 Binding of Gast and Stat6 1 0.03 2.19 0.3 5.00
123 INT275555 Binding of Ltb4r1 and COPD 1 0.01 1.02 0.3 5.00
124 INT268236 Binding of TNF and fc 1 0.04 0.2 0.29 5.00
125 INT319220 FSIP1 Regulation of APP 1 0.29 1.46 0.29 5.00
126 INT319221 FSIP1 Regulation of ADAM33 1 0.31 1.47 0.29 5.00
127 INT275548 Il10 Regulation of Mmp9 1 0.00 0.86 0.28 5.00
128 INT275556 Il10 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28 5.00
129 INT275509 IL8 Positive_regulation of Gene_expression of TIMP1 1 0.00 0.85 0.28 5.00
130 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27 5.00
131 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26 5.00
132 INT275553 Negative_regulation of Binding of Ccr5 and Ccl3 1 0.05 0.73 0.26 5.00
133 INT319229 Binding of SNRNP70 and Aia1 2 0.00 2.92 0.25 5.00
134 INT292621 Binding of IL6 and Gpt 1 0.01 3.88 0.24 5.00
135 INT226073 Binding of CRP and SHBG 2 0.10 2.14 0.24 5.00
136 INT186368 Il10 Negative_regulation of Gene_expression of Il12a 1 0.06 0.17 0.24 5.00
137 INT221383 Tlr4 Positive_regulation of Localization of Ptger2 1 0.00 1.78 0.23 5.00
138 INT186374 Il13 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23 5.00
139 INT186371 Il4 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23 5.00
140 INT259623 Binding of Eln and Elane 1 0.02 1.38 0.23 5.00
141 INT284589 Binding of ICAM1 and Crp 1 0.00 1.08 0.22 5.00
142 INT217349 Mip Positive_regulation of IL8 1 0.05 1.28 0.22 5.00
143 INT224454 TNF Positive_regulation of Gene_expression of Itgam 1 0.27 0.35 0.22 5.00
144 INT224431 TNF Positive_regulation of Gene_expression of FBXO2 1 0.47 0.35 0.22 5.00
145 INT170834 Cftr Regulation of Slc10a2 1 0.58 0.37 0.22 5.00
146 INT186351 Binding of Gast and Stat1 3 0.16 2.77 0.22 5.00
147 INT186391 TNF Positive_regulation of Gene_expression of Il17a 1 0.03 0.38 0.22 5.00
148 INT224452 Il1 Positive_regulation of Gene_expression of FBXO2 1 0.37 0.35 0.22 5.00
149 INT186358 Il1 Positive_regulation of Gene_expression of Il17a 1 0.02 0.38 0.22 5.00
150 INT224445 Il1 Positive_regulation of Gene_expression of Itgam 1 0.21 0.35 0.22 5.00
151 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
152 INT219027 Prl Positive_regulation of Localization of TRPV1 1 0.04 0.65 0.21 5.00
153 INT219028 Prl Positive_regulation of Regulation of TRPV1 1 0.03 0.65 0.21 5.00
154 INT221385 Tlr4 Positive_regulation of IL8 1 0.05 1.79 0.2 5.00
155 INT186353 Binding of Il12a and Il1 1 0.21 0.38 0.2 5.00
156 INT312708 DPP8 Positive_regulation of DPP4 1 0.24 0.54 0.19 5.00
157 INT341814 Binding of CYSLTR1 and Aia1 1 0.01 1.33 0.19 5.00
158 INT312706 DPP9 Positive_regulation of DPP4 1 0.26 0.54 0.19 5.00
159 INT179683 Binding of Col7a1 and Eln 2 0.00 3.02 0.19 5.00
160 INT236307 SFTPD Positive_regulation of IGKV2D-38 1 0.03 0.57 0.18 5.00
161 INT287145 Binding of PNN and Shbg 1 0.07 0.14 0.18 5.00
162 INT190381 IL1A Regulation of Transcription of DEFB4A 1 0.06 0.93 0.18 5.00
163 INT186759 Dep1 Positive_regulation of Positive_regulation of IgG 1 0.01 0.62 0.18 5.00
164 INT278817 EDNRA Negative_regulation of Binding of EDN1 and EDNRA 1 0.02 0.55 0.18 5.00
165 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
166 INT278818 EDNRA Negative_regulation of Binding of EDNRB and EDNRB 1 0.06 0.55 0.18 5.00
167 INT259634 Elane Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17 5.00
168 INT259633 Mmp9 Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17 5.00
169 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
170 INT193431 sal Negative_regulation of Gene_expression of Muc5b 1 0.14 1.18 0.17 5.00
171 INT341813 Binding of SUGT1 and Aia1 1 0.00 0.48 0.16 5.00
172 INT292615 Binding of IL6 and SLC17A5 1 0.01 1.8 0.16 5.00
173 INT341818 Binding of PITX2 and Aia1 1 0.00 0.53 0.16 5.00
174 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15 5.00
175 INT341815 Binding of ADORA2A and Aia1 1 0.00 1.29 0.15 5.00
176 INT186380 Binding of SOAT1 and Stat6 1 0.02 0.11 0.15 5.00
177 INT259628 Cxcl10 Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.64 0.15 5.00
178 INT259627 Cxcl10 Positive_regulation of Gene_expression of Mmp12 1 0.02 0.64 0.15 5.00
179 INT236303 Negative_regulation of IGKV2D-38 Positive_regulation of CRYGD 1 0.00 0.5 0.14 5.00
180 INT224435 TNF Regulation of Gene_expression of VEGFA 1 0.07 0.44 0.14 5.00
181 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
182 INT236316 IGKV2D-38 Positive_regulation of CRYGD 1 0.00 0.5 0.14 5.00
183 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
184 INT99241 IFNG Regulation of IL1B 2 0.21 1.26 0.14 5.00
185 INT221382 Tlr4 Positive_regulation of Localization of Ltb4r1 1 0.01 1.38 0.14 5.00
186 INT214480 SELPLG Negative_regulation of Positive_regulation of NFKB1 1 0.00 0.6 0.14 5.00
187 INT224456 Il1 Regulation of VEGFA 1 0.04 0.52 0.14 5.00
188 INT186357 Binding of Irf1 and Stat6 1 0.04 2.09 0.14 5.00
189 INT186372 Binding of Irf1 and Stat1 1 0.04 2.06 0.14 5.00
190 INT284570 Binding of Avp and Il6 1 0.04 2.17 0.13 5.00
191 INT312707 Positive_regulation of DPP4 Positive_regulation of Gene_expression of CD86 1 0.20 0.45 0.13 5.00
192 INT345280 Binding of Tlr2 and Tlr7 1 0.05 0.49 0.12 5.00
193 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
194 INT181740 Il1 Positive_regulation of Csf2 1 0.02 0 0.12 5.00
195 INT186379 Il12a Positive_regulation of Binding of IFNA1 1 0.03 0.07 0.12 5.00
196 INT312631 Binding of Musk and Agrn 1 0.40 0.63 0.12 5.00
197 INT224455 Pdgfa Regulation of VEGFA 1 0.07 0.22 0.11 5.00
198 INT259629 Binding of Adam17 and Timp3 1 0.01 0.19 0.11 5.00
199 INT321983 Glp1r Negative_regulation of Localization of Gcg 1 0.09 1.36 0.11 5.00
200 INT341811 CEP68 Regulation of Binding of CEP68 and Aia1 1 0.01 1.08 0.11 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lower Respiratory Tract Infection. They are ordered first by their pain relevance and then by number of times they were reported in Lower Respiratory Tract Infection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT155590 Gene_expression of ARIH1 8 0.58 10.76 0.24 100.00
2 INT336719 Regulation of Gene_expression of ARIH1 1 0.23 1.83 0.11 100.00
3 INT281838 Positive_regulation of Gene_expression of ARIH1 1 0.36 1.8 0 100.00
4 INT281839 Localization of ARIH1 2 0.54 3.03 0.09 100.00
5 INT65286 Binding of ARIH1 10 0.48 4.3 0.76 100.00
6 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 100.00
7 INT336717 Negative_regulation of Gene_expression of ARIH1 1 0.19 1.56 0.14 100.00
8 INT187301 Negative_regulation of ARIH1 3 0.32 1.23 0.05 100.00
9 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 100.00
10 INT187303 Regulation of ARIH1 2 0.20 1.53 0.08 100.00
11 INT74464 Binding of GNPTAB 9 0.17 3.32 1.17 100.00
12 INT217417 Binding of ERI1 2 0.36 0.99 0 100.00
13 INT138978 Positive_regulation of ARIH1 5 0.43 0.85 0 100.00
14 INT336718 Positive_regulation of Localization of ARIH1 1 0.22 0.94 0.09 100.00
15 INT293405 Transcription of URI1 1 0.03 0.74 0.07 100.00
16 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 100.00
17 INT35242 Negative_regulation of MBL2 17 0.48 12.53 1.73 99.90
18 INT164416 Gene_expression of CDA 8 0.64 5.17 1.02 99.88
19 INT297381 Transcription of BMP8B 1 0.15 0.36 0 99.80
20 INT147793 Localization of COPD 70 0.64 89.01 7.3 99.48
21 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47 99.36
22 INT10870 Regulation of IgG 67 0.59 43.27 12.74 99.28
23 INT68243 Regulation of Gene_expression of IgG 10 0.44 4.93 2.04 99.28
24 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 99.26
25 INT320680 Regulation of Gene_expression of GNPTAB 2 0.32 2.14 0.09 99.26
26 INT180743 Binding of SARS 12 0.23 17.94 0.62 99.20
27 INT49884 Negative_regulation of Gene_expression of Il4 18 0.55 14.06 8.9 98.88
28 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 98.88
29 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72 98.60
30 INT55114 Gene_expression of CRS 42 0.58 26.86 4.69 98.40
31 INT22875 Regulation of CRS 16 0.39 14.33 2.69 98.40
32 INT90820 Gene_expression of MICA 11 0.24 7.64 0.06 98.40
33 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 98.32
34 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 98.32
35 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 98.28
36 INT53929 Positive_regulation of GNPTAB 12 0.32 6.66 1.4 98.12
37 INT323622 Gene_expression of Amh 1 0.01 1.91 0 98.08
38 INT299499 Positive_regulation of Cm9 1 0.10 1.78 0.06 98.00
39 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 97.88
40 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 97.48
41 INT202053 Regulation of URB1 2 0.06 4.52 0.34 97.44
42 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 97.36
43 INT83950 Gene_expression of Cxcr1 31 0.59 27.76 13.91 97.36
44 INT73432 Gene_expression of Nppa 32 0.59 21.04 1.39 97.12
45 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 97.00
46 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 96.84
47 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92 96.84
48 INT31780 Binding of DIO2 17 0.36 10.07 10 96.56
49 INT70970 Binding of COPD 144 0.42 180.34 18.29 96.36
50 INT166177 Gene_expression of H1fnt 5 0.48 4.64 0.26 96.36
51 INT150867 Regulation of COPD 54 0.48 71.38 8.8 96.36
52 INT57339 Negative_regulation of HLA-DRA 17 0.49 7.67 1.96 96.36
53 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 96.32
54 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 95.36
55 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 95.16
56 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 94.56
57 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 94.52
58 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 94.48
59 INT180534 Gene_expression of SARS 40 0.59 35.47 0.81 94.36
60 INT64953 Negative_regulation of HLA-DRB1 9 0.58 5.15 0.56 94.08
61 INT193421 Binding of sal 2 0.26 2.08 0.45 93.92
62 INT138802 Gene_expression of CFTR 36 0.70 18.8 7.02 93.84
63 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 93.76
64 INT37103 Gene_expression of CHRNE 5 0.67 4.32 0.12 93.68
65 INT286713 Gene_expression of Musk 3 0.66 2.56 0.1 93.68
66 INT150540 Binding of TLR2 50 0.45 35.86 10.43 93.44
67 INT338464 Regulation of C5orf43 1 0.01 0.78 0 93.32
68 INT338463 Regulation of ZNF76 1 0.00 0.78 0 93.32
69 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 93.24
70 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 93.12
71 INT9660 Regulation of TNF 363 0.62 312.94 139.99 93.04
72 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 93.04
73 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 93.04
74 INT88868 Binding of MCS 45 0.40 37.43 7.98 92.84
75 INT134346 Binding of PCS 51 0.37 22.27 5.67 92.84
76 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 92.72
77 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 92.64
78 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 92.52
79 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 92.52
80 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 92.52
81 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64 92.52
82 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 92.48
83 INT219695 Positive_regulation of Gene_expression of COPD 24 0.40 33.04 3.42 92.48
84 INT18192 Regulation of Gene_expression of Alb 16 0.44 9.38 3.57 92.28
85 INT247102 Binding of MBL2 16 0.38 14.18 1.54 91.92
86 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51 91.84
87 INT140337 Negative_regulation of Cd8a 42 0.50 25.4 3.66 91.84
88 INT9732 Regulation of COL2A1 9 0.58 6.93 0.44 91.84
89 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 91.60
90 INT92648 Positive_regulation of IL12B 7 0.20 4.55 2.19 91.60
91 INT164189 Gene_expression of TREM1 82 0.62 60.77 5.85 91.44
92 INT263204 Transcription of SERPINB1 4 0.11 3.09 0.45 91.44
93 INT35148 Regulation of ANGPTL5 12 0.28 6.92 1.14 91.32
94 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 91.16
95 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 90.56
96 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 90.56
97 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 90.48
98 INT265228 Binding of TBC1D8 1 0.16 1.3 0 90.48
99 INT242110 Regulation of IGKV1-22 2 0.06 2.02 0.52 90.40
100 INT38056 Localization of Crp 71 0.78 53.14 17.03 90.28
101 INT265227 Binding of AD7 1 0.22 1.3 0 90.28
102 INT51837 Negative_regulation of TACR1 17 0.43 6.5 9.12 90.08
103 INT20982 Positive_regulation of SERPINB1 7 0.28 7.27 1.61 90.08
104 INT20981 Binding of HRAS 42 0.48 24.49 4.23 89.92
105 INT265229 Binding of PSEN2 2 0.16 1.37 0 89.92
106 INT145975 Binding of TUBA1B 1 0.36 1.2 0.09 89.88
107 INT145976 Positive_regulation of TUBA1B 1 0.49 1.2 0.09 89.88
108 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06 89.60
109 INT289504 Negative_regulation of Dync2h1 1 0.27 1.04 0 89.60
110 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13 89.44
111 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86 89.28
112 INT92769 Positive_regulation of Arsk 1 0.05 2.16 0.13 89.28
113 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 89.12
114 INT36188 Positive_regulation of PNLIP 7 0.68 5.99 1.6 89.04
115 INT61243 Gene_expression of Cyp3a2 3 0.66 2.25 0.86 88.96
116 INT168328 Regulation of Gene_expression of Cyp3a2 2 0.45 0.79 0.07 88.96
117 INT321975 Negative_regulation of Tgs1 2 0.14 1.75 0.1 88.88
118 INT252662 Binding of SYT16 1 0.01 8.05 0.45 88.72
119 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 88.64
120 INT1530 Regulation of Gh 382 0.61 115.96 112.47 88.64
121 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 88.16
122 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66 88.00
123 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 88.00
124 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 88.00
125 INT26750 Positive_regulation of Nr3c1 6 0.46 5.46 1.75 87.96
126 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 87.80
127 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 87.64
128 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42 87.52
129 INT292298 Positive_regulation of GOT2 5 0.45 3.7 1.46 87.44
130 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 87.36
131 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 87.36
132 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64 87.28
133 INT1168 Binding of PROC 62 0.38 44.15 9.04 87.12
134 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84 86.96
135 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82 86.64
136 INT19483 Positive_regulation of Ppcs 3 0.37 14.1 1.36 86.60
137 INT222031 Localization of Nt5e 16 0.75 3.1 1.73 86.44
138 INT151038 Localization of Lcn2 4 0.79 1.87 1.32 86.44
139 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 86.44
140 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85 86.28
141 INT283402 Binding of Nt5e 10 0.30 2.53 0.85 86.08
142 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 86.00
143 INT283399 Binding of Lcn2 1 0.47 5.48 1.61 85.92
144 INT147823 Localization of H1fnt 3 0.35 2.35 0.41 85.88
145 INT47030 Negative_regulation of ARMC9 22 0.38 13.08 0.47 85.68
146 INT152223 Binding of BEST1 10 0.29 6.67 1.46 85.56
147 INT112332 Positive_regulation of Gene_expression of GNPTAB 6 0.31 1.86 0.08 85.36
148 INT139674 Regulation of TAPBP 2 0.44 1.34 0.46 85.28
149 INT51486 Negative_regulation of GNPTAB 11 0.41 8.18 1.45 85.00
150 INT145693 Gene_expression of Slc10a2 5 0.78 2.54 4.13 85.00
151 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 84.80
152 INT217418 Regulation of SKAP2 1 0.13 1.17 0 84.44
153 INT89308 Positive_regulation of Binding of IFNA1 12 0.49 10.64 2.04 84.20
154 INT28703 Negative_regulation of TFPI 29 0.38 19.81 4.93 84.16
155 INT180739 Binding of ACE2 5 0.37 7.88 0.45 84.16
156 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 84.16
157 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 84.16
158 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73 84.00
159 INT57785 Positive_regulation of SGCB 25 0.69 5.01 1.49 83.88
160 INT23257 Regulation of CRP 127 0.62 100.05 21.87 83.84
161 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 83.80
162 INT149762 Regulation of MAS1 8 0.31 5.34 1.61 83.76
163 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 83.68
164 INT178209 Negative_regulation of Binding of IFNA1 7 0.39 4.8 0.89 83.68
165 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 83.36
166 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 83.12
167 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 83.00
168 INT152304 Positive_regulation of Elsgp3 1 0.30 1.17 0.21 82.92
169 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 82.84
170 INT33768 Positive_regulation of Cysltr1 87 0.46 54.66 33.52 82.72
171 INT342471 Regulation of Ath9 1 0.04 1.27 0 82.52
172 INT17010 Regulation of GP1BA 2 0.03 0.93 0.18 82.08
173 INT153269 Binding of Ccl3 10 0.48 8.87 4.69 81.52
174 INT338462 Gene_expression of IGHV3-63 1 0.02 0.82 0 81.36
175 INT194379 Localization of CRS 7 0.64 8.58 0.57 80.96
176 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 80.52
177 INT152073 Binding of IGAD1 1 0.02 2.85 0.23 80.44
178 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 80.00
179 INT30610 Localization of PCa 35 0.65 13.91 4.25 79.76
180 INT236479 Positive_regulation of Localization of SNRPB 1 0.03 1.39 0 79.76
181 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 79.52
182 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 79.36
183 INT316974 Binding of ERO1LB 1 0.05 0.48 0 79.28
184 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 79.20
185 INT57526 Regulation of Ltf 8 0.45 2.73 0.56 79.12
186 INT236475 Localization of SNRPB 1 0.04 2.85 0.13 79.12
187 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 79.04
188 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 78.96
189 INT56816 Gene_expression of Tk1 7 0.59 4.92 0.9 78.96
190 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 78.88
191 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 78.80
192 INT224722 Binding of Mcpt1 6 0.10 4.82 1.03 78.80
193 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 78.72
194 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 78.48
195 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 78.48
196 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29 78.48
197 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 78.28
198 INT161220 Binding of Ccl2 17 0.46 17.63 4.94 78.24
199 INT9995 Localization of C6orf25 13 0.69 6.48 2.29 78.16
200 INT9994 Negative_regulation of Localization of C6orf25 3 0.09 1.54 0.13 78.16
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