D:Lung Injury

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pChart

Disease Term
Synonyms Chronic Lung Injuries, Chronic Lung Injury, INJURIES LUNG, INJURIES PULMONARY, Injury Lung, Injury Pulmonary, Lung Injuries, LUNG INJURIES CHRONIC, Lung Injury Chronic, PULMONARY INJURIES, Pulmonary Injury
Documents 497
Hot Single Events 200
Hot Interactions 74

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lung Injury. They are ordered first by their relevance to Lung Injury and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12 100.00
2 INT338431 IFN1@ Regulation of Localization of Il13 1 0.13 0.63 0.12 100.00
3 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79 99.84
4 INT231843 Tlr4 Positive_regulation of Nfkb1 1 0.01 1.23 0.22 99.80
5 INT231842 Pcdh8 Positive_regulation of Akt1 1 0.00 1.59 0.4 99.72
6 INT183701 Negative_regulation of Cxcr2 Negative_regulation of Ducm1 1 0.03 0.45 0.07 99.64
7 INT310305 Serpina10 Positive_regulation of Gene_expression of Tlr4 1 0.01 0.57 0.12 99.56
8 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91 99.44
9 INT183702 Binding of Tlr3 and Pilra 1 0.02 0.64 0.11 98.68
10 INT183699 Positive_regulation of Binding of Cxcl2 and Ducm1 1 0.02 0.33 0.15 98.48
11 INT183704 Positive_regulation of Binding of Cxcl1 and Ducm1 1 0.03 0.33 0.15 98.48
12 INT183703 Binding of Cxcl1 and Ducm1 1 0.03 0.33 0.14 98.48
13 INT183696 Binding of Cxcl2 and Ducm1 1 0.02 0.33 0.14 98.48
14 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76 98.32
15 INT324863 Ros1 Regulation of Gene_expression of Tlr4 1 0.02 0.71 0.09 97.84
16 INT179928 Binding of Ephb1 and Mapk8 1 0.11 0.91 0.26 97.80
17 INT191799 PROC Negative_regulation of Binding of F2r 1 0.00 0.92 0.3 97.52
18 INT183700 Binding of Pilra and Ducm1 1 0.00 2.35 0.53 97.28
19 INT183709 Pilra Regulation of Binding of Pilra and Ducm1 1 0.00 0.59 0.11 97.28
20 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 97.28
21 INT231755 CD14 Positive_regulation of Binding of IRF6 and TLR4 1 0.03 1.6 0.11 97.28
22 INT231844 Pcdh8 Negative_regulation of Positive_regulation of Akt1 1 0.00 0.63 0.15 97.16
23 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48 96.92
24 INT231767 Positive_regulation of CD14 Positive_regulation of Binding of IRF6 1 0.04 1.6 0.11 96.64
25 INT231770 CD14 Positive_regulation of Binding of IRF6 1 0.04 1.59 0.11 96.64
26 INT310307 Tlr4 Positive_regulation of Transcription of Pus10 1 0.00 1.67 0.08 96.00
27 INT310309 Serpina10 Negative_regulation of Transcription of Pus10 1 0.00 0.84 0.04 96.00
28 INT179207 KCNAB2 Regulation of Gene_expression of ATP1A4 1 0.00 1.25 0.37 95.64
29 INT258856 P2ry2 Positive_regulation of P9Ehs1 1 0.01 0.76 0.26 95.12
30 INT352217 Tlr4 Positive_regulation of Binding of Tbce 1 0.03 0.8 0.07 94.40
31 INT222023 Gpx3 Regulation of Mapk8 1 0.01 1.43 0.18 93.12
32 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07 93.12
33 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53 92.72
34 INT231834 Trip12 Positive_regulation of Positive_regulation of Cel 1 0.00 0.75 0.05 91.88
35 INT200558 Flt1 Regulation of Aliq1 1 0.02 0.97 0 91.76
36 INT323640 Vcam1 Positive_regulation of Gene_expression of Icam1 1 0.42 1.75 0.08 91.68
37 INT258857 Binding of P2rx1 and P2ry2 1 0.22 0.81 0.29 91.52
38 INT231846 Pcdh8 Negative_regulation of Positive_regulation of Cel 1 0.00 0.91 0.14 91.40
39 INT179938 Negative_regulation of Mapk8 Negative_regulation of TNF 1 0.02 1.09 0.37 91.28
40 INT183707 Ducm1 Positive_regulation of Gene_expression of IL8 1 0.02 0.62 0.15 91.20
41 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 91.20
42 INT332247 Egf Positive_regulation of Stat6 1 0.13 1.23 0.19 91.20
43 INT332253 Il13 Positive_regulation of Stat6 1 0.08 1.18 0.19 91.20
44 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19 91.20
45 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18 89.92
46 INT231862 F2 Positive_regulation of INCENP 1 0.00 0.86 0.03 89.92
47 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64 88.44
48 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57 87.76
49 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85 87.60
50 INT250778 Binding of Socs3 and Atl1 1 0.01 0.6 0.14 87.60
51 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6 87.52
52 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36 87.52
53 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36 87.52
54 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56 87.44
55 INT73707 Ngf Regulation of Scgb1a1 1 0.25 0.61 0.58 86.28
56 INT222022 Binding of Mmp8 and Mmp9 1 0.28 1.98 0.15 86.16
57 INT318677 Xbp1 Positive_regulation of Ddit3 1 0.73 1.72 0.18 85.60
58 INT318682 Atf4 Positive_regulation of Ddit3 1 0.73 1.71 0.18 85.60
59 INT231866 INCENP Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18 85.48
60 INT191217 Cotl1 Positive_regulation of Amigo2 1 0.02 0.61 0.03 85.48
61 INT262257 Positive_regulation of NOS2 Positive_regulation of AMIGO2 1 0.02 0.99 0.16 85.04
62 INT231836 Pcdh8 Regulation of Positive_regulation of Racgap1 1 0.00 0.58 0.18 84.92
63 INT231838 Pcdh8 Regulation of Cel 1 0.00 0.39 0.15 84.68
64 INT250777 Binding of Cxcl10 and Cxcr1 1 0.14 3.1 1.04 84.56
65 INT262255 Binding of APC and F2R 1 0.05 3 0.1 84.28
66 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73 84.28
67 INT191792 Binding of F2r and Serpinc1 1 0.00 3.74 0.24 83.92
68 INT310765 Binding of Pam and Tlr2 1 0.01 0.57 0.35 83.48
69 INT318680 Binding of Cebpg and Ddit3 1 0.39 1.73 0.18 83.32
70 INT332244 Il13 Positive_regulation of Gtf3a 1 0.01 1.21 0.15 83.12
71 INT250796 Tlr4 Positive_regulation of Parp1 1 0.14 1 0.03 82.84
72 INT239398 Atp7b Regulation of OAP 1 0.03 1.1 0.35 81.84
73 INT183697 Ducm1 Positive_regulation of Gene_expression of Cxcr2 1 0.05 0.2 0.16 80.64
74 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13 80.16
75 INT239396 Atp7b Negative_regulation of Gene_expression of Icam1 1 0.07 1.69 0.26 79.84
76 INT310303 Serpina10 Positive_regulation of Hspa1a 1 0.02 0.53 0.16 79.12
77 INT231764 TLR4 Negative_regulation of HMOX1 1 0.27 1.54 0.11 78.80
78 INT335996 Mmp8 Regulation of Protein_catabolism of MIP 1 0.44 1.06 0.43 77.84
79 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15 77.20
80 INT231761 TNF Negative_regulation of HMOX1 1 0.19 1.2 0.12 77.20
81 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48 76.16
82 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75 75.00
83 INT262256 Binding of PROC and AMIGO2 1 0.00 0.72 0.04 75.00
84 INT332246 Ros1 Positive_regulation of Stat1 1 0.02 0.46 0.27 74.96
85 INT183708 Tlr3 Regulation of Binding of Tlr3 and Ducm1 1 0.02 0.99 0.14 74.80
86 INT173111 IL1B Positive_regulation of VCAM1 1 0.31 1.32 0.35 73.84
87 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34 73.40
88 INT179930 Litaf Positive_regulation of Ephb1 1 0.01 0.4 0.04 72.48
89 INT179926 Litaf Positive_regulation of Ldha 1 0.01 0.4 0.04 72.48
90 INT179927 Litaf Positive_regulation of Mapk8 1 0.02 0.39 0.04 72.48
91 INT254120 Aliq1 Positive_regulation of Tbce 1 0.00 0.68 0.43 71.60
92 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54 71.04
93 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32 71.04
94 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25 68.56
95 INT171050 Negative_regulation of F13A1 Regulation of PLG 1 0.02 0.55 0.28 68.08
96 INT171048 F13A1 Regulation of PLG 1 0.02 0.55 0.27 67.48
97 INT244325 Csf2 Regulation of Positive_regulation of Aliq1 1 0.03 1.02 0.33 67.24
98 INT179932 Trib3 Negative_regulation of Positive_regulation of Mmp9 1 0.01 0.41 0.05 66.48
99 INT179933 Trib3 Negative_regulation of Gene_expression of Mmp9 1 0.01 0.41 0.05 66.48
100 INT259636 Binding of Tbce and COPD 1 0.04 1 0.11 65.36
101 INT310314 Serpina10 Negative_regulation of TNF 1 0.00 0.8 0.05 65.36
102 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 64.96
103 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46 64.56
104 INT300867 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of Il6 1 0.02 0.42 0.08 63.92
105 INT236468 TP53 Positive_regulation of Protein_catabolism of SNRPB 1 0.00 0.52 0 63.44
106 INT259637 Binding of Mmp12 and COPD 2 0.02 1.71 0.4 63.16
107 INT240016 Binding of IL6 and POMT1 1 0.03 0.99 0.11 62.96
108 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12 62.12
109 INT332252 Stat6 Positive_regulation of Gene_expression of Il13 1 0.08 1.32 0.12 62.12
110 INT239395 Atp7b Positive_regulation of Amigo2 1 0.03 1.36 0.16 62.08
111 INT239394 Atp7b Positive_regulation of Positive_regulation of Amigo2 1 0.03 1.36 0.16 62.08
112 INT250781 IRF6 Positive_regulation of AMIGO2 1 0.02 1.25 0.35 60.48
113 INT334127 Acsm3 Positive_regulation of Vcam1 1 0.24 1.61 0.66 58.88
114 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22 57.92
115 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66 57.92
116 INT334128 Acsm3 Positive_regulation of Sele 1 0.16 1.6 0.66 57.28
117 INT220681 Binding of F10 and tf 1 0.03 1.47 0.26 57.16
118 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 57.04
119 INT215394 Binding of Csf2 and Positive_regulation of Ppara 1 0.12 0.49 0.14 56.80
120 INT239393 Atp7b Positive_regulation of Gene_expression of Amigo2 1 0.03 1.37 0.16 56.32
121 INT329303 Spp1 Positive_regulation of Localization of Il12a 1 0.12 0.92 0.12 56.04
122 INT220678 Positive_regulation of Binding of tf and Par2 1 0.16 0.71 0.2 54.08
123 INT220674 Binding of tf and Par2 1 0.13 0.71 0.2 54.08
124 INT236467 MMP9 Negative_regulation of SNRPB 1 0.01 0.45 0.1 53.92
125 INT220683 Binding of tf and PAR1 1 0.06 0.7 0.2 53.36
126 INT329304 Spp1 Negative_regulation of Gene_expression of Il10 1 0.06 0.93 0.13 53.32
127 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24 52.72
128 INT231772 TNF Positive_regulation of Gene_expression of HMOX1 1 0.21 0.96 0.1 51.68
129 INT259622 Elane Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.38 0.08 51.68
130 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 50.52
131 INT300863 Bdnf Positive_regulation of Mapk1 1 0.02 0.11 0 50.52
132 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32 50.20
133 INT300862 Bdnf Positive_regulation of Mapk14 1 0.02 0.11 0 50.20
134 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5 50.00
135 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5 50.00
136 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23 50.00
137 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23 50.00
138 INT250779 PROC Regulation of IRF6 Positive_regulation of AMIGO2 1 0.00 0.74 0.22 50.00
139 INT183694 Ducm1 Positive_regulation of Gene_expression of Tlr3 1 0.03 0.23 0.11 50.00
140 INT192908 Edn1 Positive_regulation of Ednra 1 0.21 0.35 0.07 50.00
141 INT192907 Edn1 Positive_regulation of Ednrb 1 0.10 0.35 0.07 50.00
142 INT250780 IRF6 Positive_regulation of ASAP1 1 0.06 0.34 0.04 50.00
143 INT192910 Edn1 Regulation of Col4a1 1 0.16 0.49 0 50.00
144 INT192911 Edn1 Positive_regulation of Positive_regulation of Col4a1 1 0.24 0.13 0 50.00
145 INT192909 Regulation of Edn1 Regulation of Col4a1 1 0.16 0.49 0 50.00
146 INT191214 Cotl1 Positive_regulation of Prkcg 1 0.10 1.35 0.04 49.96
147 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 49.88
148 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 49.88
149 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67 49.88
150 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67 49.88
151 INT300854 Ngf Positive_regulation of Positive_regulation of Il6 1 0.18 0.06 0 49.32
152 INT300856 Bdnf Positive_regulation of Positive_regulation of Il6 1 0.09 0.06 0 49.32
153 INT329305 Spp1 Positive_regulation of Gene_expression of Il12a 1 0.12 0.88 0.16 48.92
154 INT332251 Il13 Positive_regulation of Stat1 1 0.14 1.4 0.18 48.72
155 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49 48.64
156 INT179937 Trib3 Regulation of TNF 1 0.00 0.59 0.2 48.36
157 INT300872 Bdnf Positive_regulation of Il6 1 0.09 0.24 0.12 48.28
158 INT300858 Ngf Positive_regulation of Il6 1 0.17 0.24 0.12 48.28
159 INT220676 tf Positive_regulation of Gene_expression of Ik 1 0.00 0.66 0.21 48.24
160 INT254121 Binding of Tbce and Aliq1 1 0.00 0.69 0.2 47.48
161 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76 46.88
162 INT254511 RAC1 Positive_regulation of Positive_regulation of CYBB 1 0.14 0.39 0.03 46.80
163 INT329310 Spp1 Positive_regulation of Gene_expression of IFN1@ 1 0.48 0.88 0.19 46.36
164 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76 46.24
165 INT329309 Spp1 Regulation of Gene_expression of IFN1@ 1 0.26 0.82 0.19 45.88
166 INT317835 Nlrp3 Positive_regulation of Il18 1 0.08 1.49 0.31 45.80
167 INT254125 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Il6 1 0.00 1.23 0.5 41.40
168 INT254124 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Tbxa2r 1 0.00 0.62 0.25 41.40
169 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45 39.20
170 INT179935 Binding of Jun and Mapk8 1 0.04 0.61 0.19 38.72
171 INT269995 Positive_regulation of Binding of Nfkb2 and Tpx2 1 0.05 0.51 0.21 37.96
172 INT352216 Binding of Tlr4 and Tbce 1 0.01 0.3 0.04 37.56
173 INT269994 Binding of Nfkb2 and Tpx2 1 0.04 0.51 0.21 37.36
174 INT197191 Tlr4 Positive_regulation of Vwf 1 0.33 0.3 0.08 36.24
175 INT197190 Positive_regulation of Tlr4 Positive_regulation of Vwf 1 0.33 0.31 0.08 36.24
176 INT300865 Ngf Positive_regulation of Gene_expression of Il6 1 0.17 0 0 34.80
177 INT300870 Bdnf Positive_regulation of Gene_expression of Il6 1 0.10 0 0.05 34.48
178 INT334136 Binding of IFNA1 and Acsm3 1 0.01 4.52 2.19 33.12
179 INT231763 Binding of HSPD1 and TLR2 1 0.12 2 0.19 33.04
180 INT231765 Binding of HSPD1 and TLR4 1 0.13 1.94 0.16 33.04
181 INT345157 Lpar1 Positive_regulation of Gene_expression of Gtf3a 1 0.00 0.89 0.15 32.32
182 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25 31.48
183 INT324877 CYBB Positive_regulation of Ros1 1 0.00 0.26 0 30.88
184 INT324875 CYBB Positive_regulation of Ros1 Positive_regulation of Localization of Ros1 1 0.00 0.31 0 30.88
185 INT323352 Binding of F8 and VWF 5 0.08 2.22 0.33 30.36
186 INT343794 Binding of F8 and PTPRC 1 0.00 0.69 0.09 30.00
187 INT310306 Tlr4 Regulation of Gene_expression of Chd7 1 0.01 0.25 0.04 28.28
188 INT281351 Tenc1 Regulation of Agtr2 1 0.06 0.8 0.21 26.16
189 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15 25.68
190 INT145830 Mdp1 Positive_regulation of Nod2 1 0.34 0.52 0.13 25.00
191 INT319729 Binding of Rela and Crebbp 1 0.02 0.88 0.37 24.04
192 INT319703 Binding of Rela and Crebbp Positive_regulation of Binding of Rela 1 0.00 0.37 0.12 24.04
193 INT319726 Crebbp Positive_regulation of Binding of Rela 1 0.02 0.37 0.12 24.04
194 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12 24.04
195 INT231848 Pcdh8 Positive_regulation of Prkaca 1 0.00 0 0.04 23.92
196 INT231845 Pcdh8 Positive_regulation of Prkca 1 0.00 0 0.04 23.72
197 INT231839 Pcdh8 Positive_regulation of Src 1 0.00 0 0.04 23.36
198 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05 22.32
199 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15 22.16
200 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11 22.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lung Injury. They are ordered first by their pain relevance and then by number of times they were reported in Lung Injury. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 100.00
2 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
3 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 100.00
4 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 100.00
5 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 100.00
6 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47 100.00
7 INT13295 Positive_regulation of Cdkn2a 18 0.68 13.02 5.47 100.00
8 INT219695 Positive_regulation of Gene_expression of COPD 24 0.40 33.04 3.42 100.00
9 INT260596 Positive_regulation of Gene_expression of FDX1 2 0.05 1.75 0.54 100.00
10 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 100.00
11 INT181525 Localization of Il13 24 0.66 21.51 6.55 100.00
12 INT70860 Binding of SNRPB 17 0.35 7 1.46 100.00
13 INT236477 Regulation of Binding of SNRPB 1 0.02 0.1 0 100.00
14 INT152894 Regulation of Positive_regulation of Mapk14 9 0.45 6.01 1.74 99.98
15 INT178399 Regulation of Positive_regulation of Mapk8 4 0.44 3.4 0.23 99.98
16 INT102268 Gene_expression of H2-S 20 0.75 10.77 2.03 99.96
17 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 99.96
18 INT151122 Positive_regulation of Litaf 7 0.35 3.58 0.92 99.96
19 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 99.96
20 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 99.96
21 INT143357 Binding of Ros1 48 0.36 27.76 6 99.96
22 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.92
23 INT191221 Positive_regulation of Amigo2 20 0.12 24.24 2.31 99.92
24 INT200554 Positive_regulation of Aliq1 29 0.22 33.02 5.32 99.92
25 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 99.92
26 INT208898 Gene_expression of FDX1 8 0.10 5.58 2.39 99.92
27 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 99.92
28 INT174684 Gene_expression of Tlr6 2 0.44 2.62 0.36 99.92
29 INT123890 Localization of Cxcl2 11 0.67 8.03 3.65 99.92
30 INT99778 Localization of Cxcl10 12 0.75 14.24 3.91 99.92
31 INT171059 Localization of PDX1 8 0.56 6.7 1.9 99.92
32 INT231228 Regulation of Gene_expression of SFTPC 1 0.60 3.8 0.73 99.90
33 INT336000 Positive_regulation of Gene_expression of Cxcl3 1 0.01 1.71 0.15 99.88
34 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12 99.88
35 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.88
36 INT178497 Positive_regulation of Gene_expression of Angpt1 4 0.19 3.65 0.39 99.88
37 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 99.84
38 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84 99.84
39 INT151124 Localization of Litaf 2 0.10 2.03 0.57 99.84
40 INT29327 Positive_regulation of Ace 13 0.67 8.79 4.33 99.84
41 INT179923 Negative_regulation of Localization of Litaf 1 0.02 0.85 0.19 99.84
42 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 99.82
43 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37 99.80
44 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 99.80
45 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 99.78
46 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02 99.76
47 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 99.76
48 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65 99.76
49 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.74
50 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 99.74
51 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.74
52 INT6484 Binding of IL1B 122 0.47 75.84 35.07 99.74
53 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06 99.74
54 INT173114 Positive_regulation of Binding of IL1B 6 0.49 2.56 1.22 99.74
55 INT191222 Binding of Amigo2 4 0.05 5.42 0.87 99.72
56 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 99.72
57 INT117147 Negative_regulation of Gene_expression of Cxcl2 19 0.55 15.33 6.57 99.68
58 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 99.68
59 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 99.68
60 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 99.66
61 INT191784 Positive_regulation of Cel 4 0.03 3.18 1.16 99.66
62 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 99.64
63 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.64
64 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78 99.64
65 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 99.64
66 INT16066 Positive_regulation of Cxcl3 3 0.65 1.59 0.49 99.64
67 INT231737 Localization of OAP 5 0.50 7.4 2.63 99.64
68 INT131818 Binding of Parp1 14 0.46 8.74 1.76 99.62
69 INT186456 Gene_expression of SFTPC 2 0.75 11.46 2.38 99.62
70 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 99.60
71 INT58527 Gene_expression of Prtn3 20 0.71 15.99 2.9 99.60
72 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 99.60
73 INT168304 Positive_regulation of SNRPB 17 0.25 9.62 1.64 99.60
74 INT83358 Positive_regulation of Elane 8 0.21 8.14 1.83 99.60
75 INT259620 Regulation of Gene_expression of Prtn3 1 0.26 0.87 0.18 99.60
76 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 99.60
77 INT28923 Negative_regulation of Ldha 8 0.58 4.94 3.11 99.60
78 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85 99.60
79 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 99.60
80 INT97912 Gene_expression of Sod3 25 0.78 22.44 3.28 99.58
81 INT97910 Positive_regulation of Gene_expression of Sod3 13 0.70 15.56 2.46 99.58
82 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56 99.56
83 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36 99.56
84 INT310292 Gene_expression of Serpina10 1 0.03 4.13 0.67 99.56
85 INT222017 Regulation of Gene_expression of Mmp8 1 0.27 1 0.04 99.56
86 INT183684 Regulation of Gene_expression of Cxcr2 1 0.57 1.42 0.37 99.54
87 INT120697 Negative_regulation of SCNN1G 6 0.32 3.53 0.92 99.54
88 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.54
89 INT120694 Negative_regulation of Gene_expression of SCNN1G 3 0.32 2.08 0.19 99.54
90 INT83951 Gene_expression of Cxcr2 31 0.71 19.36 7.24 99.52
91 INT231821 Positive_regulation of Pcdh8 1 0.01 0.85 0.21 99.52
92 INT191783 Positive_regulation of Pnp 21 0.67 22.51 1.66 99.50
93 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28 99.48
94 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 99.48
95 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08 99.48
96 INT74157 Negative_regulation of Positive_regulation of Il10 5 0.43 5.83 3.56 99.46
97 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 99.46
98 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 99.44
99 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 99.44
100 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13 99.44
101 INT109411 Gene_expression of SAT1 61 0.77 67.99 3.08 99.42
102 INT49866 Negative_regulation of Parp1 53 0.58 35.37 8.84 99.40
103 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 99.40
104 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 99.40
105 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 99.40
106 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 99.40
107 INT86717 Negative_regulation of Positive_regulation of NOS1 18 0.30 8.88 5.2 99.40
108 INT10171 Binding of Gtf3a 33 0.36 19.84 5.1 99.40
109 INT239384 Localization of Atp7b 1 0.58 1 0.14 99.40
110 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 99.36
111 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14 99.36
112 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 99.36
113 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15 99.36
114 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.34
115 INT202357 Gene_expression of Map2k3 13 0.65 1.94 0.09 99.34
116 INT222014 Negative_regulation of Gene_expression of Map2k3 1 0.41 1.55 0.09 99.34
117 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.34
118 INT302876 Gene_expression of Cxcl3 4 0.56 2.95 1.08 99.34
119 INT156874 Positive_regulation of Gene_expression of S100a8 26 0.49 32.8 8.99 99.34
120 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 99.32
121 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07 99.32
122 INT6852 Localization of TNF 883 0.81 705.95 270.84 99.32
123 INT63586 Regulation of Parp1 5 0.43 3.28 1.68 99.32
124 INT75523 Regulation of MAPK8 21 0.33 11.18 4.28 99.32
125 INT117920 Regulation of MAPK14 14 0.38 8.75 4.31 99.32
126 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42 99.32
127 INT87282 Regulation of MAPK3 9 0.60 7.61 1.65 99.32
128 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 99.30
129 INT230518 Positive_regulation of Hmgb1 1 0.11 1.1 0.21 99.28
130 INT183683 Negative_regulation of Negative_regulation of Insrr 1 0.01 0.69 0.22 99.24
131 INT259614 Regulation of Negative_regulation of Prtn3 1 0.26 0.78 0.15 99.24
132 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 99.22
133 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 99.20
134 INT239390 Positive_regulation of Phosphorylation of Atp7b 1 0.39 3.49 0.49 99.20
135 INT306800 Positive_regulation of Localization of SFTPD 1 0.16 2.1 0.68 99.20
136 INT239388 Phosphorylation of Atp7b 1 0.63 1.74 0.25 99.20
137 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 99.20
138 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 99.20
139 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54 99.20
140 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83 99.20
141 INT120696 Gene_expression of SCNN1G 9 0.43 5.46 1.03 99.18
142 INT184257 Positive_regulation of Gene_expression of Mmp8 7 0.49 6.32 2.74 99.16
143 INT49437 Gene_expression of OAP 25 0.54 20.12 7.34 99.16
144 INT239884 Positive_regulation of Transcription of PR@ 1 0.67 0.32 0 99.16
145 INT143231 Positive_regulation of CRYGD 20 0.49 14.87 3.67 99.16
146 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 99.14
147 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 99.14
148 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7 99.14
149 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68 99.14
150 INT220861 Positive_regulation of Mmp8 14 0.50 12.21 4.6 99.12
151 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 99.12
152 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 99.12
153 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04 99.08
154 INT222015 Regulation of Negative_regulation of Map2k3 1 0.43 0.79 0.12 99.08
155 INT222016 Regulation of Negative_regulation of Mapk8 1 0.44 0.79 0.12 99.08
156 INT186452 Positive_regulation of SFTPB 7 0.47 6.43 0.03 99.08
157 INT47952 Negative_regulation of H2-S 4 0.42 5.05 0.87 99.04
158 INT191795 Localization of ALLC 1 0.05 0.65 0.24 99.04
159 INT352046 Regulation of Positive_regulation of Cd48 1 0.05 0.64 0.09 99.04
160 INT200552 Regulation of Aliq1 3 0.08 7.55 1.42 99.02
161 INT35548 Regulation of Mme 9 0.45 10.62 2.97 99.02
162 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 99.02
163 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 99.00
164 INT245577 Localization of SFTPD 7 0.63 10.43 1.84 99.00
165 INT16461 Negative_regulation of Gene_expression of PROC 13 0.24 4.39 2.17 99.00
166 INT51983 Negative_regulation of Prtn3 23 0.34 12.54 5 98.96
167 INT5539 Negative_regulation of Mme 75 0.59 28.91 41.84 98.96
168 INT239886 Transcription of PR@ 1 0.69 0.32 0 98.96
169 INT18778 Gene_expression of Ugt1a2 17 0.35 9.91 6.87 98.94
170 INT318446 Negative_regulation of Cxcl3 2 0.40 2.73 0.43 98.92
171 INT71779 Positive_regulation of Gene_expression of MAPK1 27 0.47 21.41 5.39 98.88
172 INT71783 Positive_regulation of Gene_expression of MAPK3 9 0.59 4.59 3.05 98.88
173 INT71785 Gene_expression of MAPK3 22 0.75 11.35 8.21 98.88
174 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58 98.88
175 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 98.86
176 INT111680 Gene_expression of P2ry2 20 0.58 9.23 7.39 98.86
177 INT130203 Gene_expression of P2ry4 14 0.50 8.79 4.82 98.86
178 INT154804 Negative_regulation of Positive_regulation of PARP1 2 0.34 3.88 0.33 98.84
179 INT194850 Positive_regulation of Adora2b 43 0.61 20.57 13.89 98.84
180 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 98.82
181 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65 98.80
182 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 98.80
183 INT258848 Regulation of Gene_expression of Cxcl2 7 0.43 8.71 1.77 98.80
184 INT239392 Positive_regulation of Gene_expression of Amigo2 1 0.04 2.87 0.68 98.80
185 INT318665 Negative_regulation of Gene_expression of Atf4 1 0.56 5.16 0.85 98.78
186 INT155780 Gene_expression of Mmp8 19 0.77 15.85 6.33 98.76
187 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 98.74
188 INT222018 Positive_regulation of Map2k7 1 0.02 0.77 0.03 98.72
189 INT150854 Negative_regulation of Cxcr2 7 0.54 4.12 1.06 98.70
190 INT31186 Negative_regulation of Insrr 81 0.37 24.91 55.94 98.70
191 INT183691 Negative_regulation of Cxcr1 1 0.08 0.58 0.19 98.70
192 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 98.68
193 INT180922 Negative_regulation of Mmp8 4 0.43 8.35 3.72 98.68
194 INT20650 Positive_regulation of F2 26 0.69 15.49 5.08 98.66
195 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 98.64
196 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 98.64
197 INT95788 Positive_regulation of Positive_regulation of Mapk1 83 0.69 24.75 25.84 98.64
198 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 98.64
199 INT160828 Regulation of Gene_expression of Ros1 29 0.21 13.97 3.75 98.56
200 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 98.54
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