D:Lyme Disease

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Disease Term
Synonyms Arthritis Lyme, Borrelia Burgdorferi, Borreliosis Lyme, DISEASE LYME, Early Lyme Disease, INFECTION BY BORRELIA BURGDORFERI, Lyme Arthritis, Lyme Borreliosis, LYME DISORDER, Lymes Disease, Mid Lyme Disease
Documents 526
Hot Single Events 134
Hot Interactions 10

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lyme Disease. They are ordered first by their relevance to Lyme Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38 100.00
2 INT256320 Binding of CYP26A1 and Hapln1 1 0.01 1.27 0.14 100.00
3 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 99.10
4 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29 98.12
5 INT300548 Napa Positive_regulation of Gene_expression of Il23a 1 0.05 0.86 0.28 98.12
6 INT288202 Negative_regulation of Cd14 Positive_regulation of Positive_regulation of Mapk14 1 0.09 1.08 0.64 92.44
7 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33 86.00
8 INT172004 IL17A Positive_regulation of Gene_expression of IL6 2 0.14 1.35 0.34 85.04
9 INT172011 IgG Regulation of Ighm 1 0.00 0.77 0 84.88
10 INT198595 Binding of CFH and CFHR1 3 0.41 1.36 0.03 82.88
11 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 71.04
12 INT288203 Binding of Cd14 and Mapk14 1 0.08 0.63 0.31 71.04
13 INT288205 Binding of Cd14 and Myd88 1 0.10 0.57 0.28 71.04
14 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54 70.84
15 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31 70.84
16 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51 69.84
17 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08 50.00
18 INT285909 AKT1 Regulation of Phosphorylation of Bad 1 0.01 0.4 0 50.00
19 INT285908 AKT1 Regulation of Pten 1 0.01 0.53 0 50.00
20 INT285878 Negative_regulation of Binding of CCND1 and CDK4 1 0.00 0.44 0 50.00
21 INT285910 Pten Regulation of AKT1 1 0.00 0.53 0 50.00
22 INT284048 Binding of Cia1 and Vtcn1 1 0.02 1.37 0.6 44.44
23 INT338514 Binding of FHL1 and CFH 1 0.08 0.37 0 41.60
24 INT338508 Binding of FHL1 and CFHR1 1 0.08 0.37 0 41.28
25 INT288201 Mapk14 Positive_regulation of Cish 1 0.03 0.06 0.82 34.64
26 INT288208 Binding of Mapk14 and Positive_regulation of Akt1 1 0.01 0.42 0.35 25.60
27 INT254277 Binding of Hand1 and Tnfsf11 1 0.02 0.08 0.08 13.40
28 INT218510 Binding of C3 and Cfb 1 0.02 0.53 0.2 8.40
29 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
30 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 5.00
31 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 5.00
32 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31 5.00
33 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
34 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05 5.00
35 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
36 INT103928 Binding of Cd28 and Trav6-3 3 0.03 0.55 0.98 5.00
37 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00
38 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
39 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93 5.00
40 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77 5.00
41 INT284040 Gtf3a Positive_regulation of Csf3 1 0.01 1.7 0.7 5.00
42 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55 5.00
43 INT254279 Il13 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54 5.00
44 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54 5.00
45 INT284041 Negative_regulation of Binding of Vtcn1 and Sh4 1 0.07 1.29 0.5 5.00
46 INT284045 Binding of Vtcn1 and Sh4 1 0.06 1.29 0.5 5.00
47 INT284049 Arigm1 Negative_regulation of Cia1 1 0.00 1.11 0.5 5.00
48 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
49 INT300544 Il22 Positive_regulation of Gene_expression of Mcpt1 1 0.02 1.15 0.47 5.00
50 INT284044 Sh4 Positive_regulation of Cia1 1 0.20 0.72 0.43 5.00
51 INT300547 Il6 Positive_regulation of Il21 1 0.02 0.78 0.39 5.00
52 INT254278 Binding of Il13 and Il4 1 0.02 0.74 0.38 5.00
53 INT284046 Sh4 Negative_regulation of Vtcn1 1 0.10 1.13 0.36 5.00
54 INT284039 Binding of fc and Vtcn1 1 0.02 0.58 0.35 5.00
55 INT171874 Binding of SQLE and MRAP 1 0.00 1.29 0.35 5.00
56 INT300549 Il1 Regulation of Gene_expression of Irf4 1 0.01 0.63 0.33 5.00
57 INT244234 Cxcr2 Positive_regulation of Cxcr1 1 0.16 0.08 0.32 5.00
58 INT244233 Ccr1 Positive_regulation of Cxcr1 1 0.16 0.08 0.32 5.00
59 INT284047 Vtcn1 Negative_regulation of Gene_expression of Ighg2b 1 0.05 0.68 0.3 5.00
60 INT299745 Binding of Masp1 and IgG 1 0.03 0.69 0.26 5.00
61 INT254283 Il10 Negative_regulation of Nfatc1 1 0.02 0.31 0.25 5.00
62 INT300546 Binding of Il23a and Il1 1 0.01 0.5 0.25 5.00
63 INT171250 Binding of BMI1 and OAP 1 0.13 1.02 0.22 5.00
64 INT254281 Il4 Negative_regulation of Gene_expression of Acp5 1 0.02 0.41 0.22 5.00
65 INT336946 Binding of ITGA4 and VCAM1 1 0.03 2.02 0.21 5.00
66 INT244243 Regulation of Binding of IL8 and Ccl3 1 0.04 0.05 0.18 5.00
67 INT244240 Binding of IL8 and Ccr5 1 0.03 0.05 0.18 5.00
68 INT244241 Binding of IL8 and Ccl3 1 0.05 0.05 0.18 5.00
69 INT244242 Negative_regulation of Binding of IL8 and Ccl3 1 0.06 0.05 0.18 5.00
70 INT244230 Binding of IL8 and CCL18 1 0.02 0.23 0.17 5.00
71 INT244235 Binding of Cxcl1 and Ccl3 1 0.14 0.23 0.17 5.00
72 INT244244 Binding of CCL18 and Cxcl1 1 0.04 0.23 0.17 5.00
73 INT244236 Binding of Cxcl1 and Ccl4 1 0.11 0.23 0.17 5.00
74 INT265215 Cd28 Regulation of Transcription of thd 1 0.00 0 0.15 5.00
75 INT218499 Cfb Negative_regulation of ap 1 0.00 0.74 0.13 5.00
76 INT300545 Il6 Positive_regulation of Gene_expression of Il1r1 1 0.02 0.42 0.11 5.00
77 INT269013 Binding of CSRP1 and COPD 1 0.08 1.3 0.11 5.00
78 INT265211 Il4 Negative_regulation of Il23a 1 0.01 0.07 0.1 5.00
79 INT254284 Binding of TNF and Tnfsf11 1 0.04 0.44 0.1 5.00
80 INT265212 Cd28 Negative_regulation of Gene_expression of Il17a 1 0.10 0 0.09 5.00
81 INT288210 Regulation of Tlr2 Positive_regulation of Akt1 1 0.03 0.09 0.08 5.00
82 INT288206 Tlr2 Positive_regulation of Akt1 1 0.04 0.09 0.08 5.00
83 INT265222 Binding of Cd28 and Gopc 1 0.04 0 0.08 5.00
84 INT265221 Binding of Cd28 and Positive_regulation of Gene_expression of Il17a 1 0.15 0.09 0.08 5.00
85 INT288204 Akt1 Regulation of Mapk14 1 0.01 0.09 0.07 5.00
86 INT218511 Cfb Positive_regulation of C5 1 0.01 0.29 0.06 5.00
87 INT218503 Cfb Positive_regulation of C3 1 0.01 0.29 0.06 5.00
88 INT265224 Cd28 Positive_regulation of Gene_expression of IFN1@ 1 0.34 0.25 0.05 5.00
89 INT265218 Cd28 Positive_regulation of Gene_expression of Gopc 1 0.06 0.25 0.05 5.00
90 INT265225 Cd28 Positive_regulation of IFN1@ 1 0.47 0.25 0.05 5.00
91 INT265226 Binding of IFN1@ and Il2 1 0.07 0.19 0.04 5.00
92 INT281733 LTK Regulation of IgG 1 0.00 1.37 0.03 5.00
93 INT288199 Binding of Ptprc and Trav6-3 1 0.00 0.05 0.03 5.00
94 INT254282 Sfpi1 Positive_regulation of Binding of Pam16 1 0.02 0.23 0.03 5.00
95 INT254285 Sfpi1 Positive_regulation of Gene_expression of THPO 1 0.02 0.17 0.03 5.00
96 INT175832 Binding of GML and SLC25A11 1 0.10 0 0 5.00
97 INT218506 Binding of LCN1 and Cfb 1 0.04 0.25 0 5.00
98 INT252020 Binding of HLA-A and ELOVL1 1 0.01 1.41 0 5.00
99 INT338513 Binding of CFHR1 and CFHR5 1 0.13 0.43 0 5.00
100 INT218509 Binding of BCR and Cfb 1 0.00 0.18 0 5.00
101 INT265217 Negative_regulation of Binding of Ctla4 and Cd86 1 0.15 0.14 0 5.00
102 INT218508 Negative_regulation of Binding of C3 and Cfb 1 0.01 0 0 5.00
103 INT218513 Binding of C3AR1 and ap 1 0.00 0.36 0 5.00
104 INT218505 Binding of C5 and Cfb 1 0.01 0.29 0 5.00
105 INT218514 BCR Negative_regulation of Binding of Cfb 1 0.00 0.18 0 5.00
106 INT218531 Binding of C6 and TCN2 1 0.00 0 0 5.00
107 INT338510 Binding of CFH and CFHR5 1 0.13 0.23 0 5.00
108 INT218532 Binding of C5 and LCN1 1 0.06 0.49 0 5.00
109 INT269014 Binding of EGR1 and COPD 1 0.12 0.96 0 5.00
110 INT218504 ap Regulation of CP 1 0.00 0.28 0 5.00
111 INT265223 Negative_regulation of Binding of Ctla4 and Cd28 1 0.18 0.14 0 5.00
112 INT176919 Binding of DLD and Bpifa2 1 0.00 0.08 0 5.00
113 INT338511 Binding of CFHR2 and CFHR5 1 0.11 0.66 0 5.00
114 INT218498 Binding of C4b and Daf2 1 0.04 0.26 0 5.00
115 INT176920 DLD Positive_regulation of Binding of Bpifa2 1 0.00 0.08 0 5.00
116 INT338512 Binding of CFH and CFHR2 1 0.20 0.67 0 5.00
117 INT265216 Cd28 Positive_regulation of Gene_expression of Il17a 1 0.10 0 0 5.00
118 INT218512 Binding of TCN2 and Cfb 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lyme Disease. They are ordered first by their pain relevance and then by number of times they were reported in Lyme Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 99.98
2 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 99.98
3 INT25544 Positive_regulation of Hapln1 3 0.12 8.58 1.44 99.84
4 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 99.80
5 INT19399 Gene_expression of Rf 43 0.36 33.39 13.53 99.80
6 INT43931 Binding of CFH 49 0.48 31.85 3.96 99.78
7 INT44679 Binding of CFHR1 3 0.34 3.39 0.28 99.78
8 INT107207 Binding of FHL1 3 0.40 0.76 0.5 99.78
9 INT134651 Binding of TLR4 89 0.48 66.96 23.19 99.72
10 INT185738 Binding of Cd14 28 0.45 14.41 3.25 99.66
11 INT11794 Gene_expression of Cd2 27 0.76 17.31 10.99 99.56
12 INT135028 Positive_regulation of Cd14 34 0.59 16.19 5.73 99.40
13 INT49104 Positive_regulation of Gene_expression of Vcam1 30 0.69 36.52 7.64 99.38
14 INT63978 Regulation of Gene_expression of Sele 5 0.18 4.59 1.24 99.38
15 INT288184 Binding of Tlr1 8 0.29 4.73 0.4 99.38
16 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 99.38
17 INT146898 Positive_regulation of Binding of CFH 3 0.44 2.01 0.17 99.20
18 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.16
19 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 99.16
20 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 99.16
21 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 99.08
22 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 99.08
23 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 99.04
24 INT135022 Gene_expression of Cd14 79 0.76 36.37 10.63 98.98
25 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 98.88
26 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 98.88
27 INT274290 Binding of Fhl1 3 0.03 1.16 0.1 98.48
28 INT189790 Negative_regulation of Binding of Cd14 1 0.54 1.13 0.39 98.48
29 INT17646 Gene_expression of HSPA8 8 0.77 6.75 0.64 98.12
30 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 98.08
31 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 98.08
32 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 98.08
33 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06 98.08
34 INT116748 Positive_regulation of Gene_expression of Pik3r1 18 0.49 9.83 4.63 98.08
35 INT110021 Positive_regulation of Gene_expression of Mapk14 29 0.46 19.06 3.86 98.08
36 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 97.76
37 INT112027 Gene_expression of Pik3r1 58 0.75 30.9 15.95 97.62
38 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 97.54
39 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 97.54
40 INT165430 Gene_expression of SPR 2 0.59 1.27 0.75 97.36
41 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 97.12
42 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 97.12
43 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 97.00
44 INT288189 Negative_regulation of Negative_regulation of Tlr2 1 0.26 0.43 0.28 96.98
45 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 96.92
46 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 96.84
47 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 96.68
48 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43 96.62
49 INT121752 Gene_expression of IL11 54 0.62 18.05 7.16 96.40
50 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 96.24
51 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 96.16
52 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 96.00
53 INT15132 Gene_expression of TNFRSF1A 33 0.75 20.09 5.93 94.92
54 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 94.92
55 INT15131 Gene_expression of CD2 20 0.75 9.47 5.01 94.60
56 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 94.40
57 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 94.40
58 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 94.08
59 INT75929 Gene_expression of IL9 61 0.43 24.71 16.17 93.60
60 INT165434 Regulation of SPR 4 0.24 2.14 2.33 93.52
61 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 93.36
62 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 93.28
63 INT256314 Regulation of Hapln1 1 0.05 0.45 0.08 93.20
64 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 93.08
65 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 92.96
66 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68 92.96
67 INT338646 Positive_regulation of Gene_expression of CFHR5 1 0.23 0.16 0 92.96
68 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 92.56
69 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 92.48
70 INT83450 Positive_regulation of Localization of CCL2 28 0.70 22.14 9.83 92.48
71 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 92.48
72 INT285900 Positive_regulation of Localization of MIP 1 0.49 1.09 0.17 92.48
73 INT285899 Positive_regulation of Localization of CCL3 1 0.12 1.08 0.17 92.48
74 INT254314 Negative_regulation of Cd14 10 0.42 4.24 1.86 92.44
75 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08 92.40
76 INT140684 Gene_expression of ALCAM 10 0.45 3.75 0.24 91.88
77 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 91.84
78 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 91.84
79 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01 91.84
80 INT83292 Gene_expression of MIP 35 0.75 25.22 10.14 91.84
81 INT16234 Positive_regulation of CFH 25 0.50 26.05 3.33 91.80
82 INT27593 Positive_regulation of FHL1 3 0.37 2.29 0.75 91.80
83 INT288191 Positive_regulation of Localization of Pik3r1 4 0.15 1.27 0.81 91.80
84 INT346634 Transcription of GDE1 1 0.04 0.37 0 91.60
85 INT65698 Localization of CCL2 118 0.81 77.54 32.69 91.24
86 INT12339 Localization of IL8 437 0.81 251.87 117.39 91.24
87 INT12082 Localization of IL6 365 0.81 241.78 105.78 91.24
88 INT91336 Localization of MIP 5 0.78 2.97 1.79 91.24
89 INT65699 Localization of CCL3 7 0.78 2.56 1.25 91.24
90 INT184022 Negative_regulation of Cish 3 0.35 1.79 0.48 91.12
91 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 90.96
92 INT165911 Localization of Pik3r1 15 0.51 7.94 3.2 90.96
93 INT25546 Gene_expression of Hapln1 8 0.14 5.58 0.99 90.84
94 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 90.48
95 INT227973 Gene_expression of Gm2404 9 0.10 4.21 0 90.16
96 INT204722 Positive_regulation of ALCAM 4 0.30 1.69 0.11 89.80
97 INT184031 Gene_expression of Cish 14 0.49 9.82 1.86 89.76
98 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 89.48
99 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 89.36
100 INT189791 Negative_regulation of Gene_expression of Cd14 9 0.40 4.2 0.82 89.28
101 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 89.16
102 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 89.16
103 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 89.16
104 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 89.16
105 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 89.16
106 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 89.16
107 INT13354 Transcription of TNF 108 0.72 85.81 42.32 89.16
108 INT36054 Transcription of IL1B 53 0.72 32.64 17.31 89.16
109 INT48892 Transcription of Il10 31 0.71 27.26 16.77 89.16
110 INT51014 Transcription of IL2 42 0.71 21.56 12.7 89.16
111 INT50933 Transcription of Il6 38 0.72 24.31 11.58 89.16
112 INT67397 Transcription of Il4 15 0.54 11.36 6.06 89.16
113 INT92654 Transcription of RETNLB 3 0.01 3.33 1.12 89.16
114 INT66082 Regulation of CSAD 5 0.27 4.72 1.99 89.12
115 INT241404 Gene_expression of Caprin1 3 0.18 1.38 0.77 88.64
116 INT103923 Negative_regulation of Positive_regulation of Mapk14 23 0.53 13.95 10.64 88.16
117 INT204775 Regulation of Tlr2 21 0.41 13.6 2.18 87.64
118 INT198682 Positive_regulation of Ifna 5 0.49 2.61 0.37 87.60
119 INT269016 Negative_regulation of Gene_expression of ALCAM 1 0.18 0.67 0 86.96
120 INT338612 Gene_expression of CFHR5 1 0.36 1.41 0 86.88
121 INT37430 Gene_expression of Gpi1 61 0.63 54.63 13.87 86.36
122 INT128161 Gene_expression of DDIT3 20 0.75 17.14 5.13 86.08
123 INT23635 Positive_regulation of MMP12 31 0.59 28.19 17.95 84.88
124 INT186882 Gene_expression of RTEL1 13 0.27 13.45 0.49 84.80
125 INT19188 Binding of Igh-6 11 0.48 2.97 4.88 84.40
126 INT11788 Positive_regulation of Rrsv 36 0.46 10.08 9.68 84.20
127 INT135024 Regulation of Cd14 6 0.57 4.9 1.52 83.28
128 INT117113 Regulation of Mapk14 28 0.45 16.71 11.99 83.28
129 INT32602 Positive_regulation of Positive_regulation of Rrsv 2 0.16 0.7 0.69 82.92
130 INT117083 Localization of RTEL1 5 0.60 9.1 0.8 82.04
131 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 81.84
132 INT160564 Gene_expression of Il22 64 0.55 59.29 20.9 80.56
133 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2 80.32
134 INT201425 Positive_regulation of Localization of IgG 4 0.08 2.2 0.1 80.12
135 INT15129 Positive_regulation of Gene_expression of Cd2 3 0.49 0.95 0.89 79.84
136 INT28774 Localization of LAMC2 6 0.73 3.2 0.76 79.52
137 INT338607 Gene_expression of CFHR2 1 0.42 1.27 0 79.44
138 INT72747 Localization of IgG 55 0.53 30.88 4.19 78.84
139 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82 78.64
140 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 77.76
141 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 77.68
142 INT1829 Gene_expression of CFH 71 0.75 64.24 2.49 77.60
143 INT182215 Regulation of CXCR5 4 0.27 4.49 2.18 77.44
144 INT166203 Positive_regulation of Cia1 62 0.43 75.94 31.37 76.36
145 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 75.60
146 INT227970 Negative_regulation of Gm2404 1 0.02 0.68 0 75.36
147 INT166914 Binding of CTSC 1 0.36 1.3 0.06 75.28
148 INT133029 Regulation of TLR2 18 0.56 11.31 2.62 75.00
149 INT164189 Gene_expression of TREM1 82 0.62 60.77 5.85 75.00
150 INT38814 Positive_regulation of Aspt1 9 0.63 6.89 3.06 75.00
151 INT15133 Regulation of HLA-DRA 19 0.34 5.84 3.9 75.00
152 INT15127 Regulation of Cd2 4 0.44 1.06 2.38 75.00
153 INT15128 Positive_regulation of Cd2 3 0.64 1.45 1.25 75.00
154 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 75.00
155 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01 75.00
156 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 75.00
157 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 75.00
158 INT188682 Localization of Cd86 3 0.68 2.75 0.6 74.20
159 INT171879 Binding of ENOX1 9 0.03 3.37 0.77 73.96
160 INT9655 Regulation of Il6 98 0.62 70.92 31.95 73.76
161 INT236839 Positive_regulation of CXCL13 14 0.44 19.27 5.81 73.28
162 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 73.28
163 INT236842 Positive_regulation of Gene_expression of CXCL13 6 0.32 3.91 2.55 73.28
164 INT265208 Negative_regulation of thd 7 0.01 1.99 0.42 72.60
165 INT338625 Localization of CFHR2 1 0.33 0.07 0 72.24
166 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96 71.52
167 INT176388 Localization of IL18BP 2 0.68 1.42 0.78 71.12
168 INT92417 Gene_expression of Rrsv 7 0.60 6.6 0.51 70.60
169 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 70.56
170 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 68.48
171 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 67.52
172 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 66.00
173 INT215120 Negative_regulation of Localization of IgG 5 0.16 3.44 0.43 65.84
174 INT354843 Protein_catabolism of CR1 1 0.22 1.67 0 65.72
175 INT354842 Protein_catabolism of CLU 1 0.28 1.6 0 64.80
176 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91 64.36
177 INT219268 Negative_regulation of Negative_regulation of Mapk14 2 0.38 0.99 0.8 64.36
178 INT231499 Positive_regulation of Negative_regulation of Mapk14 3 0.24 1.58 0.43 64.36
179 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 63.84
180 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 63.80
181 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 63.68
182 INT165213 Regulation of Gene_expression of Cd4 12 0.40 9.14 1.57 63.52
183 INT227971 Positive_regulation of Gm2404 3 0.06 0.66 0 63.44
184 INT192404 Localization of Ighm 15 0.48 5.8 0.85 62.56
185 INT229958 Negative_regulation of CFB 3 0.01 0.06 0 61.92
186 INT204717 Gene_expression of Sh4 5 0.73 30.17 10.19 61.36
187 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 61.00
188 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35 60.48
189 INT194167 Protein_catabolism of CFH 2 0.59 0.63 0.09 60.20
190 INT338605 Positive_regulation of Protein_catabolism of CFH 1 0.33 0.11 0 60.20
191 INT338644 Protein_catabolism of FHL1 1 0.25 0.06 0 59.88
192 INT338653 Positive_regulation of Protein_catabolism of FHL1 1 0.14 0.06 0 59.88
193 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 59.04
194 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 59.04
195 INT135527 Negative_regulation of Gene_expression of Cd4 17 0.43 6.72 1.09 59.04
196 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 58.80
197 INT57252 Negative_regulation of PGR 22 0.43 12.95 3.33 58.72
198 INT199029 Binding of SPR 2 0.06 0.85 0.6 57.80
199 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 56.80
200 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 56.24
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