D:Lymphoproliferative Disease

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Disease Term
Synonyms Disorder Lymphoproliferative, DISORDER X LINKED LYMPHOPROLIFERATIVE, Disorders Lymphoproliferative, DISORDERS X LINKED LYMPHOPROLIFERATIVE, Duncan S Syndrome, Duncan Syndrome, Duncans Syndrome, FATAL EPSTEIN BARR VIRUS SYNDROME, Lymphoproliferative Diseases, LYMPHOPROLIFERATIVE DISORDER, Lymphoproliferative Disorder X Linked
Documents 248
Hot Single Events 114
Hot Interactions 8

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Lymphoproliferative Disease. They are ordered first by their relevance to Lymphoproliferative Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 100.00
2 INT332587 MND1 Positive_regulation of Binding of RAPH1 and MND1 1 0.00 2.21 0.03 100.00
3 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18 96.60
4 INT249666 Binding of CD81 and GOPC 1 0.06 1.31 0 95.04
5 INT351013 PROK1 Regulation of ISG20 1 0.01 0.76 0 94.88
6 INT228120 PDLIM7 Positive_regulation of Localization of Il10 1 0.51 1.37 0 92.32
7 INT274469 IL12A Positive_regulation of Gene_expression of IL6 1 0.04 1.39 0.06 83.68
8 INT249664 Binding of CD81 and CHCHD2 1 0.00 2.51 0 81.92
9 INT287814 Apex1 Positive_regulation of Gene_expression of Rnf128 1 0.03 0.15 0.03 79.48
10 INT228108 Il10 Negative_regulation of H2-Eb1 1 0.04 1.38 0 73.00
11 INT274472 IL12A Negative_regulation of Gene_expression of FGF2 1 0.02 0.36 0.14 71.76
12 INT274473 IL12A Regulation of Gene_expression of FGF2 1 0.02 0.36 0.14 71.76
13 INT274474 IL12A Regulation of Gene_expression of VEGFA 1 0.04 0.36 0.14 70.96
14 INT202507 Nfasc Positive_regulation of Gene_expression of Bcl2 1 0.10 0.7 0 59.80
15 INT193697 Apaf1 Positive_regulation of CASP9 1 0.02 1.84 0.12 59.36
16 INT137237 SST Regulation of SHOX 1 0.06 0.25 0.25 57.28
17 INT323704 TNF Positive_regulation of Gene_expression of MIR146A 1 0.13 0.97 0.38 50.00
18 INT174820 IL6 Positive_regulation of VEGFA 1 0.20 3.32 0.12 41.28
19 INT174821 VEGFA Positive_regulation of Gene_expression of IL6 1 0.20 3.13 0.12 40.48
20 INT283632 Binding of Selp and Ie 1 0.00 0.22 0 29.20
21 INT283633 Binding of Vcam1 and Ie 1 0.00 0.17 0 28.08
22 INT299762 Binding of Cd28 and Positive_regulation of Gene_expression of Il2 1 0.03 0.07 0.04 21.68
23 INT299766 APCS Positive_regulation of Gene_expression of Cd80 1 0.04 0.86 0.5 20.00
24 INT299767 APCS Positive_regulation of Gene_expression of Cd86 1 0.07 0.86 0.5 20.00
25 INT299764 APCS Positive_regulation of Cd86 1 0.02 0.86 0.5 20.00
26 INT299765 APCS Positive_regulation of Cd80 1 0.04 0.85 0.49 20.00
27 INT193696 Binding of CD8A and Trav6-3 1 0.00 0.85 0 17.84
28 INT283630 Cd36 Regulation of Positive_regulation of Ie 1 0.00 0 0 11.60
29 INT283631 Positive_regulation of Binding of Cd36 and Ie 1 0.00 0 0 11.60
30 INT283629 Binding of Cd36 and Ie 1 0.00 0 0 11.60
31 INT350700 Binding of Bcl6 and thd 1 0.00 0.21 0.08 8.44
32 INT350692 Binding of Bcl6 and Hand1 1 0.02 0.16 0.08 8.44
33 INT350720 Binding of Bcl6 and TBX21 1 0.07 0.22 0.08 8.44
34 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0 7.76
35 INT350721 Binding of Hand1 and TBX21 1 0.13 0.22 0.08 7.00
36 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1 6.60
37 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
38 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
39 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
40 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
41 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
42 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
43 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
44 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
45 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 5.00
46 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
47 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91 5.00
48 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42 5.00
49 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36 5.00
50 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15 5.00
51 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
52 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
53 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05 5.00
54 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
55 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 5.00
56 INT323698 Gene_expression of MIR146A Regulation of FAF1 1 0.16 1.82 0.86 5.00
57 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 5.00
58 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
59 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
60 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58 5.00
61 INT350716 Binding of CD58 and Casp8 1 0.03 1.81 0.58 5.00
62 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
63 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 5.00
64 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
65 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44 5.00
66 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
67 INT323702 HGF Regulation of Gene_expression of CRP 1 0.01 0.81 0.43 5.00
68 INT350693 Mir326 Positive_regulation of Regulation of thd 1 0.00 1.32 0.41 5.00
69 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4 5.00
70 INT350698 Mir326 Regulation of Ets1 1 0.01 1.27 0.4 5.00
71 INT287819 Binding of CD80 and Cd28 1 0.25 0.7 0.4 5.00
72 INT287818 Negative_regulation of Binding of CD80 and Cd28 1 0.29 0.7 0.4 5.00
73 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39 5.00
74 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
75 INT279369 Binding of ADA and Ifx 1 0.29 0.27 0.35 5.00
76 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
77 INT350701 Mthfd1 Regulation of Gene_expression of Cd4 1 0.03 1.46 0.33 5.00
78 INT316488 Il22 Positive_regulation of Il10 1 0.29 0.63 0.32 5.00
79 INT316483 Il22ra1 Positive_regulation of Il10 1 0.27 0.62 0.31 5.00
80 INT316487 Il22 Regulation of Il22ra1 1 0.12 0.61 0.31 5.00
81 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31 5.00
82 INT323710 TRAF6 Regulation of MIR146A 1 0.06 0.55 0.28 5.00
83 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28 5.00
84 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
85 INT351007 Binding of IL2 and IL2RA 1 0.33 1.33 0.26 5.00
86 INT323701 MIR146A Positive_regulation of Localization of TNF 1 0.14 0.98 0.25 5.00
87 INT258398 Binding of IL6R and JAK1 1 0.01 0.75 0.23 5.00
88 INT323699 MIR146A Regulation of Gene_expression of FAF1 1 0.22 0.93 0.23 5.00
89 INT323709 MIR146A Negative_regulation of TNF 1 0.12 0.46 0.23 5.00
90 INT316491 Socs3 Positive_regulation of Il11ra1 1 0.45 0.92 0.22 5.00
91 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
92 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 5.00
93 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
94 INT202508 Gpbar1 Positive_regulation of Positive_regulation of Nfasc 1 0.00 0.57 0.19 5.00
95 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00
96 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18 5.00
97 INT316477 Stat3 Positive_regulation of Il10 1 0.39 0.35 0.18 5.00
98 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18 5.00
99 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18 5.00
100 INT323711 FAF1 Regulation of MIR146A 1 0.10 0.87 0.18 5.00
101 INT350702 Rc3h1 Positive_regulation of Protein_catabolism of Icos 1 0.35 1.56 0.18 5.00
102 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18 5.00
103 INT323706 Binding of FAF1 and MIR146A 1 0.13 0.87 0.18 5.00
104 INT350717 MIR219-1 Negative_regulation of Zfp238 1 0.01 0.4 0.16 5.00
105 INT316484 Akt1 Positive_regulation of Positive_regulation of Stat3 1 0.01 0.87 0.16 5.00
106 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16 5.00
107 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16 5.00
108 INT258906 Binding of HLA-B and HLA-DRB1 1 0.31 1.36 0.15 5.00
109 INT350719 MIR219-1 Negative_regulation of Foxj3 1 0.01 0.4 0.15 5.00
110 INT258909 Binding of HLA-DOA and NDUFA2 1 0.03 1.44 0.15 5.00
111 INT316479 Il6 Positive_regulation of Snai1 1 0.24 0.33 0.15 5.00
112 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15 5.00
113 INT316490 Il6 Positive_regulation of Positive_regulation of Stat3 1 0.50 0.33 0.15 5.00
114 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 0.00 0.4 0.15 5.00
115 INT350723 MIR219-1 Negative_regulation of Sox6 1 0.01 0.4 0.15 5.00
116 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14 5.00
117 INT299763 Binding of APC and CTLA4 Positive_regulation of Ido1 1 0.11 0.31 0.14 5.00
118 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 5.00
119 INT228111 Il10 Negative_regulation of Gene_expression of Ik 1 0.01 0.44 0.13 5.00
120 INT228119 Il10 Negative_regulation of H2 1 0.07 0.38 0.13 5.00
121 INT228110 Chrm2 Positive_regulation of Localization of Il10 1 0.33 0.66 0.13 5.00
122 INT324128 Binding of Cd4 and Cd40 2 0.29 0.3 0.13 5.00
123 INT228113 H2 Negative_regulation of Gene_expression of Ik 1 0.00 0.33 0.13 5.00
124 INT345280 Binding of Tlr2 and Tlr7 1 0.05 0.49 0.12 5.00
125 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12 5.00
126 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11 5.00
127 INT284309 Tlr4 Positive_regulation of Mir155 3 0.18 0.51 0.11 5.00
128 INT274471 IL12A Negative_regulation of Gene_expression of IL10 1 0.02 0.99 0.1 5.00
129 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1 5.00
130 INT350694 Uts2r Negative_regulation of Negative_regulation of Rc3h1 1 0.05 0.79 0.1 5.00
131 INT350695 Mir101a Positive_regulation of Protein_catabolism of Icos 1 0.05 0.8 0.1 5.00
132 INT323700 MIR146A Regulation of FAF1 1 0.22 0.69 0.09 5.00
133 INT274470 Binding of IL12A and GOPC 1 0.02 0.6 0.09 5.00
134 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09 5.00
135 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09 5.00
136 INT81998 Binding of F13A1 and F8 1 0.00 0.47 0.09 5.00
137 INT202505 Binding of Cd40lg and Positive_regulation of Positive_regulation of Nfasc 1 0.09 0.45 0.08 5.00
138 INT228116 Tlr4 Positive_regulation of Localization of Il10 1 0.09 0.06 0.08 5.00
139 INT276375 Binding of Prdm1 and MIR9-1 1 0.12 1.12 0.08 5.00
140 INT276383 Binding of PRDM1 and Mirlet7a-1 1 0.39 1.12 0.08 5.00
141 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
142 INT277807 CD40LG Regulation of CD40 1 0.21 0.17 0.08 5.00
143 INT351011 Binding of HDAC9 and TSPYL2 1 0.04 0.63 0.08 5.00
144 INT276334 Binding of Prdm1 and Mirlet7a-1 1 0.12 1.13 0.08 5.00
145 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08 5.00
146 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08 5.00
147 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08 5.00
148 INT276384 Binding of Mirlet7a-1 and MIR9-1 1 0.39 1.12 0.08 5.00
149 INT350708 Foxp3 Regulation of Socs1 1 0.08 0.21 0.07 5.00
150 INT279286 Binding of TXK and VEGFA 3 0.05 2.35 0.07 5.00
151 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
152 INT234381 Binding of CD40 and PPARA 1 0.19 1.39 0.07 5.00
153 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
154 INT316492 Stat3 Positive_regulation of Socs3 1 0.46 0.19 0.06 5.00
155 INT202506 Psmb8 Positive_regulation of Nfasc 1 0.01 0.59 0.06 5.00
156 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00
157 INT351010 ISG20 Positive_regulation of Transcription of IL2 1 0.31 0.46 0.05 5.00
158 INT351009 IL2RG Positive_regulation of Transcription of IL2 1 0.27 0.44 0.05 5.00
159 INT276337 Timp1 Positive_regulation of Il10 1 0.01 0.76 0.05 5.00
160 INT203638 Binding of MR1 and GOPC 1 0.04 1.43 0.05 5.00
161 INT351012 IL2RB Positive_regulation of Gene_expression of IL15 1 0.10 0.42 0.05 5.00
162 INT351008 IL2RB Positive_regulation of Gene_expression of IL2 1 0.18 0.42 0.05 5.00
163 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05 5.00
164 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 5.00
165 INT276386 Gtf3a Regulation of PTPN6 1 0.00 0.86 0.04 5.00
166 INT234379 BAX Positive_regulation of CASP3 1 0.04 1.16 0.04 5.00
167 INT316485 Stat3 Positive_regulation of Transcription of Ccnd1 1 0.23 1.27 0.04 5.00
168 INT234382 Binding of TNF and TNFSF10 1 0.11 1.2 0.04 5.00
169 INT205862 CNTN2 Positive_regulation of TNF 1 0.01 0.08 0.04 5.00
170 INT316489 Stat3 Positive_regulation of Transcription of Ccnb1 1 0.02 1.27 0.04 5.00
171 INT234380 Negative_regulation of Binding of CD40 and CD40LG 1 0.16 1.4 0.04 5.00
172 INT204246 ETFA Regulation of CD68 1 0.37 1.05 0.04 5.00
173 INT276381 Timp1 Positive_regulation of CD44 1 0.07 0.72 0.04 5.00
174 INT316486 Stat3 Positive_regulation of Transcription of Cdc2b 1 0.28 1.27 0.04 5.00
175 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04 5.00
176 INT316499 Stat3 Positive_regulation of Transcription of MYC 1 0.55 1.27 0.04 5.00
177 INT350704 Foxp3 Negative_regulation of Gene_expression of Mir142 1 0.02 0.13 0.04 5.00
178 INT276392 Timp1 Regulation of PTPN6 1 0.02 0.87 0.04 5.00
179 INT276376 Gtf3a Regulation of CD44 1 0.00 0.86 0.04 5.00
180 INT234383 Positive_regulation of Binding of TNF and TNFSF10 1 0.15 1.2 0.04 5.00
181 INT276385 Timp1 Regulation of CD44 1 0.04 0.87 0.04 5.00
182 INT204247 S100B Regulation of CD68 1 0.03 1.05 0.04 5.00
183 INT323707 LBR Positive_regulation of MIR146A 1 0.02 0.1 0.03 5.00
184 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03 5.00
185 INT276377 Binding of Lgals1 and KRT20 1 0.00 1.11 0.03 5.00
186 INT350696 Mir31 Regulation of Gene_expression of Foxp3 1 0.04 0 0.03 5.00
187 INT345281 Binding of CASP1 and Nlrp3 1 0.02 0.31 0.03 5.00
188 INT316478 Binding of Stat3 and Hist1h3f 1 0.05 1.08 0.03 5.00
189 INT293367 Binding of CABIN1 and Ppia 1 0.00 0.19 0.03 5.00
190 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03 5.00
191 INT276388 Il22 Positive_regulation of STAT3 1 0.03 1.3 0.03 5.00
192 INT316496 Il17a Positive_regulation of VEGFA 1 0.11 0.65 0.03 5.00
193 INT345282 Binding of CASP1 and Pycard 1 0.01 0.3 0.03 5.00
194 INT276305 Binding of LGALS1 and KRT20 1 0.01 1.11 0.03 5.00
195 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03 5.00
196 INT312303 Positive_regulation of FLT1 Positive_regulation of VEGFA 1 0.38 0.73 0.03 5.00
197 INT293368 Binding of CSH1 and Ppia 1 0.00 0.19 0.03 5.00
198 INT316481 Positive_regulation of Stat3 Positive_regulation of Localization of Hand1 1 0.19 1.48 0.03 5.00
199 INT277693 Stat6 Positive_regulation of Positive_regulation of Casp3 1 0.01 1.01 0 5.00
200 INT287062 Gopc Positive_regulation of Positive_regulation of Vav1 1 0.18 0.15 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Lymphoproliferative Disease. They are ordered first by their pain relevance and then by number of times they were reported in Lymphoproliferative Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 100.00
2 INT156130 Binding of SERPING1 29 0.42 26.16 2.52 100.00
3 INT332592 Binding of MND1 1 0.08 9.21 0.16 99.80
4 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 99.78
5 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.78
6 INT174480 Binding of IL7 3 0.38 4.55 1.69 99.76
7 INT116362 Positive_regulation of C4A 17 0.69 11.53 1.03 99.40
8 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 99.40
9 INT113516 Negative_regulation of Fas 16 0.51 8.37 5.32 99.36
10 INT88020 Positive_regulation of Fas 32 0.70 19.78 9.97 99.36
11 INT10706 Regulation of Il6 150 0.62 93.23 62.34 99.34
12 INT14301 Binding of CSF2 82 0.48 67.95 8.98 99.24
13 INT268582 Gene_expression of MIR17 8 0.58 9.99 0.9 99.20
14 INT268553 Positive_regulation of Gene_expression of MIR17 3 0.09 3.37 0.32 99.20
15 INT264689 Negative_regulation of IGFALS 10 0.33 12.58 0.45 98.64
16 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12 98.44
17 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 98.24
18 INT323736 Positive_regulation of MIR146A 9 0.27 8.3 2.21 98.08
19 INT157401 Gene_expression of Ctla4 21 0.65 15.43 3.2 98.00
20 INT241857 Gene_expression of EPOR 14 0.77 5.21 0.13 98.00
21 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 97.88
22 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 97.84
23 INT17326 Binding of Plg 14 0.43 11.72 1.94 97.82
24 INT23620 Negative_regulation of C4A 24 0.57 15.1 2.23 97.68
25 INT7632 Protein_catabolism of AMPD1 1 0.70 0.56 0.15 97.44
26 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 97.18
27 INT11346 Binding of Mtx1 39 0.41 24.88 21.21 97.04
28 INT78429 Positive_regulation of TRGC1 11 0.44 4.6 2.1 96.76
29 INT70051 Transcription of IL12A 7 0.25 5.61 3.39 96.68
30 INT6852 Localization of TNF 883 0.81 705.95 270.84 96.56
31 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81 96.40
32 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 96.28
33 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 96.22
34 INT99780 Positive_regulation of Cxcl10 43 0.69 39.67 13.27 96.20
35 INT217214 Negative_regulation of MIR17 2 0.24 1.37 0.2 95.88
36 INT350634 Gene_expression of 2010001M09Rik 1 0.04 1.22 0.1 95.60
37 INT111192 Positive_regulation of PPL 9 0.60 4.27 0.81 95.40
38 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 94.88
39 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27 94.88
40 INT66852 Gene_expression of Fcer2 15 0.14 9.74 1.27 94.88
41 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17 94.76
42 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 94.24
43 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 94.24
44 INT112694 Negative_regulation of Positive_regulation of Fas 5 0.42 4.3 0.89 94.24
45 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52 94.20
46 INT300347 Positive_regulation of Gene_expression of MIR146A 23 0.35 25.04 9.62 94.08
47 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09 93.84
48 INT165054 Gene_expression of MIR146A 45 0.58 82.87 28.82 93.68
49 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 93.64
50 INT9210 Regulation of IL6 166 0.62 125.61 49.95 93.64
51 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 93.64
52 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 93.60
53 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54 93.40
54 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 93.24
55 INT87199 Negative_regulation of PSS 9 0.50 5.66 0.68 93.20
56 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 93.00
57 INT149861 Gene_expression of CD52 14 0.75 9.35 0.47 92.64
58 INT90792 Localization of Il10 144 0.80 87.88 30.03 92.32
59 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 92.12
60 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 92.12
61 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 91.76
62 INT111139 Localization of Tp53 4 0.45 2.4 0.09 91.72
63 INT177584 Gene_expression of MR1 80 0.58 46.48 5.48 91.48
64 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 91.24
65 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 91.20
66 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 90.48
67 INT194901 Regulation of Nfasc 8 0.21 5.76 1.15 89.76
68 INT176888 Positive_regulation of MR1 29 0.67 11.68 1.71 89.72
69 INT45155 Negative_regulation of Polymerase 18 0.51 15.18 1.38 89.52
70 INT100822 Localization of Fas 8 0.74 6.13 0.48 88.64
71 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 88.16
72 INT83325 Regulation of Gene_expression of Il2ra 8 0.48 3.59 2.36 88.12
73 INT111143 Regulation of Gene_expression of KRT20 22 0.26 5.65 1.93 88.12
74 INT111138 Regulation of Gene_expression of Fcer2 1 0.05 0.43 0.09 88.12
75 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 87.68
76 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 87.68
77 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 87.36
78 INT60162 Gene_expression of Ie 41 0.58 23.77 1.52 87.36
79 INT38674 Regulation of KRT20 32 0.44 19 2.15 87.28
80 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 87.08
81 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16 87.08
82 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 87.08
83 INT293779 Localization of CD52 2 0.27 3.15 0 86.72
84 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94 85.64
85 INT11807 Gene_expression of Il2 266 0.78 112 64.97 85.60
86 INT175392 Binding of Ugcg 13 0.08 10.16 0.89 85.56
87 INT350687 Positive_regulation of MIR17 1 0.05 0.44 0.14 84.84
88 INT40322 Binding of Pnp 12 0.38 11.13 1.78 84.64
89 INT217814 Gene_expression of MIR181A1 9 0.58 7.94 0.15 84.52
90 INT31117 Binding of Casp3 14 0.23 5.27 0.93 84.00
91 INT328286 Positive_regulation of C1orf38 1 0.01 2.93 0.33 83.96
92 INT217804 Negative_regulation of MITF 19 0.01 19.95 0.57 83.60
93 INT201570 Gene_expression of CR2 11 0.48 14.21 0.22 83.20
94 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 82.76
95 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 82.76
96 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 82.72
97 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 82.68
98 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 82.68
99 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 82.28
100 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01 82.24
101 INT130581 Negative_regulation of Mier1 2 0.20 0.56 0.3 82.08
102 INT350659 Negative_regulation of Mir126 1 0.05 0.48 0.16 82.08
103 INT350645 Negative_regulation of Mir497 1 0.10 0.43 0.13 82.08
104 INT7134 Localization of KNG1 127 0.79 65.73 67.97 82.00
105 INT70817 Negative_regulation of Transcription of Il2 5 0.40 0.25 0.87 81.96
106 INT87458 Binding of CD81 4 0.18 6.02 0.59 81.92
107 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 81.72
108 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35 81.72
109 INT59320 Transcription of Il2 32 0.69 6.39 4.95 81.48
110 INT245872 Positive_regulation of HLA-G 1 0.02 0.78 0 81.20
111 INT350688 Negative_regulation of Gene_expression of MIR181A1 1 0.42 0.41 0.07 80.96
112 INT249680 Binding of CHCHD2 1 0.01 2.45 0 80.48
113 INT228644 Positive_regulation of Negative_regulation of SERPING1 5 0.46 4.21 0.21 80.32
114 INT223746 Binding of Il10 12 0.36 9.49 1.73 80.20
115 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75 79.96
116 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13 79.60
117 INT287805 Gene_expression of Rnf128 1 0.47 0.15 0.03 79.48
118 INT174520 Negative_regulation of Gene_expression of HLA-DOA 10 0.14 2.62 0.17 79.20
119 INT43907 Binding of CD79A 28 0.48 28.11 3.04 78.92
120 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 78.88
121 INT350691 Localization of DICER1 1 0.08 1.18 0.23 78.64
122 INT23955 Regulation of Vim 16 0.25 14.21 2.04 77.80
123 INT104979 Gene_expression of MITF 51 0.62 54.83 6.91 77.72
124 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14 77.64
125 INT124943 Regulation of NCAM1 10 0.44 5.25 1.27 77.56
126 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87 77.52
127 INT90493 Negative_regulation of PSMB9 3 0.54 0.88 0.15 77.52
128 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 77.04
129 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 76.56
130 INT234414 Gene_expression of NR2C2AP 1 0.04 2.19 0 76.56
131 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 75.00
132 INT299760 Negative_regulation of Cd80 2 0.16 1.06 0.55 74.96
133 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 74.76
134 INT196393 Negative_regulation of Cd86 9 0.22 4.24 1.17 74.76
135 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 74.72
136 INT38672 Binding of KRT20 69 0.39 48.01 6.31 74.68
137 INT73091 Binding of TNFRSF8 21 0.44 6.64 0.93 74.68
138 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 74.56
139 INT65070 Gene_expression of SHOX 9 0.55 7.72 1.84 74.16
140 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93 73.76
141 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 73.68
142 INT153705 Gene_expression of CLDN3 5 0.58 4.07 0.37 73.24
143 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76 72.52
144 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 72.44
145 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 72.40
146 INT114311 Negative_regulation of Gene_expression of Gpt 33 0.38 17.83 4.94 72.40
147 INT1869 Negative_regulation of SLC17A5 12 0.42 5.51 0.75 72.40
148 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 72.00
149 INT6481 Binding of TNF 624 0.48 510.2 214.82 71.80
150 INT69283 Gene_expression of PHEX 25 0.75 7.81 0.64 71.80
151 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 71.76
152 INT177467 Negative_regulation of MTRF1 22 0.05 11.84 5.57 71.56
153 INT241861 Regulation of EPCAM 7 0.17 7.23 1.22 71.28
154 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 71.28
155 INT276311 Gene_expression of Irf4 6 0.64 4.95 0.37 70.80
156 INT197122 Transcription of CRS 2 0.49 3.09 0.18 70.80
157 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51 70.72
158 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 70.64
159 INT5870 Negative_regulation of IFNA2 20 0.49 12 4.3 70.60
160 INT276314 Gene_expression of Mum1 1 0.16 3.85 0.03 70.48
161 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 70.00
162 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 69.68
163 INT70021 Localization of BCL2 23 0.74 21.6 1.09 69.68
164 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97 69.60
165 INT235466 Localization of BCL6 3 0.27 5 0.29 68.88
166 INT217825 Regulation of Gene_expression of MITF 3 0.00 5.2 1.47 68.44
167 INT26434 Localization of MME 17 0.81 8.67 2.3 68.16
168 INT166755 Localization of PHEX 2 0.73 1.16 0.28 67.84
169 INT172216 Binding of Bak1 5 0.25 8.48 0.33 67.52
170 INT352131 Binding of Bcl2l11 1 0.05 4.17 0.05 67.52
171 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 67.28
172 INT144275 Negative_regulation of Atm 9 0.59 8.48 0.36 67.12
173 INT177593 Positive_regulation of Gene_expression of MR1 17 0.43 9.36 1.13 67.12
174 INT56160 Binding of Ifx 14 0.36 11.39 5.74 66.40
175 INT174477 Negative_regulation of IL7 11 0.47 10.35 3.69 66.20
176 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 65.68
177 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 65.68
178 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 65.68
179 INT137239 Gene_expression of CASZ1 8 0.71 4.63 4.19 65.44
180 INT137238 Gene_expression of CORT 1 0.58 1.01 0.96 65.44
181 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 64.80
182 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22 64.80
183 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 64.60
184 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 64.08
185 INT239578 Positive_regulation of Gene_expression of CD52 2 0.16 1.37 0.03 63.76
186 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 63.56
187 INT186858 Gene_expression of CEP350 1 0.01 1 0 62.80
188 INT234422 Gene_expression of PML 14 0.75 15.93 1.14 62.68
189 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 62.08
190 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 62.08
191 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 60.76
192 INT251459 Binding of Ie 18 0.20 6.62 0.75 60.72
193 INT50580 Binding of PPIG 39 0.36 11.17 12.34 60.00
194 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 59.84
195 INT169996 Positive_regulation of Negative_regulation of Fas 2 0.25 1.69 0.28 59.84
196 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47 59.52
197 INT197121 Positive_regulation of Atm 24 0.69 6.81 0.25 59.00
198 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 57.92
199 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 56.24
200 INT274482 Regulation of Positive_regulation of IFN1@ 4 0.44 1.44 0.33 56.24
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