D:Malformed Nails

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pChart

Disease Term
Synonyms Abnormal Nail, Abnormal Nails, Abnormalities Nail, Abnormality Nail, MALFORMED NAIL, Nail Abnormal, Nail Abnormalities, Nail Abnormality, Nail Malformed, Nails Abnormal, PACHYONYCHIA
Documents 22
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Malformed Nails. They are ordered first by their relevance to Malformed Nails and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44 5.00
2 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41 5.00
3 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41 5.00
4 INT329801 Binding of CAMP and IFNA1 1 0.03 1.48 0.4 5.00
5 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
6 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17 5.00
7 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15 5.00
8 INT329797 Positive_regulation of TLR2 Positive_regulation of Gene_expression of IL6 1 0.02 1.67 0.11 5.00
9 INT329802 Positive_regulation of TLR2 Regulation of Gene_expression of IL6 1 0.01 1.67 0.11 5.00
10 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Malformed Nails. They are ordered first by their pain relevance and then by number of times they were reported in Malformed Nails. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 82.80
2 INT277254 Negative_regulation of Satb2 1 0.43 3.26 0.04 77.84
3 INT277257 Binding of Satb2 1 0.37 2.51 0 77.84
4 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 72.96
5 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 72.96
6 INT244771 Gene_expression of Satb2 4 0.68 1.27 0.03 72.40
7 INT277258 Localization of Satb2 1 0.81 3.59 0.04 59.08
8 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 41.56
9 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 40.40
10 INT76177 Binding of YOD1 2 0.15 1.29 0.21 23.80
11 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
12 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
13 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
14 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
15 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
16 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
17 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
18 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
19 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
20 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
21 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
22 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
23 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
24 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
25 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
26 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
27 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
28 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 5.00
29 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
30 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
31 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 5.00
32 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
33 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 5.00
34 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
35 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
36 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
37 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 5.00
38 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
39 INT6484 Binding of IL1B 122 0.47 75.84 35.07 5.00
40 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 5.00
41 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
42 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 5.00
43 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
44 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
45 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71 5.00
46 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33 5.00
47 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87 5.00
48 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44 5.00
49 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07 5.00
50 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9 5.00
51 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 5.00
52 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 5.00
53 INT133030 Positive_regulation of Gene_expression of TLR2 53 0.65 38.15 10.65 5.00
54 INT58904 Localization of TH1L 40 0.68 27.11 10.52 5.00
55 INT150540 Binding of TLR2 50 0.45 35.86 10.43 5.00
56 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3 5.00
57 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 5.00
58 INT123142 Gene_expression of DEFB4A 54 0.76 36.14 10.02 5.00
59 INT81929 Negative_regulation of Gene_expression of IL10 41 0.57 27.99 9.87 5.00
60 INT91667 Localization of IL12A 39 0.74 25.51 7.36 5.00
61 INT81493 Transcription of CCL2 20 0.65 13.63 6.78 5.00
62 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4 5.00
63 INT170470 Binding of CD14 27 0.35 14.89 5.16 5.00
64 INT246031 Gene_expression of IL22 10 0.40 9.48 5.11 5.00
65 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 5.00
66 INT97131 Positive_regulation of CD14 25 0.67 12.03 4.21 5.00
67 INT79413 Gene_expression of CAMP 13 0.75 8.3 4.02 5.00
68 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99 5.00
69 INT173519 Positive_regulation of Localization of IFNA1 27 0.49 24.48 3.9 5.00
70 INT103281 Transcription of CCL5 10 0.67 5.95 3.7 5.00
71 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65 5.00
72 INT167478 Positive_regulation of Gene_expression of DCPS 23 0.27 14.75 3.37 5.00
73 INT97138 Positive_regulation of Gene_expression of CD14 17 0.48 9.07 3.35 5.00
74 INT186805 Transcription of TLR2 12 0.63 9.66 3.04 5.00
75 INT181848 Negative_regulation of CD14 16 0.43 8.14 2.95 5.00
76 INT105378 Regulation of IL12A 6 0.26 8.82 2.15 5.00
77 INT222903 Gene_expression of TLR1 20 0.60 8.77 1.9 5.00
78 INT120014 Transcription of CCL3 5 0.69 3.03 1.82 5.00
79 INT157769 Binding of LY96 8 0.47 2.5 1.59 5.00
80 INT79412 Positive_regulation of Gene_expression of CAMP 5 0.49 3.73 1.55 5.00
81 INT146914 Negative_regulation of TLR2 12 0.53 7.41 1.23 5.00
82 INT295694 Localization of DNAI1 4 0.15 3.28 1.09 5.00
83 INT144232 Negative_regulation of Gene_expression of Il12b 4 0.41 2.26 1.01 5.00
84 INT107107 Gene_expression of DEFA1 4 0.01 3.37 1 5.00
85 INT77947 Regulation of Gene_expression of IL12A 6 0.24 5.23 0.94 5.00
86 INT48066 Binding of CAMP 3 0.36 2.69 0.93 5.00
87 INT237858 Positive_regulation of MYD88 5 0.49 2.93 0.9 5.00
88 INT266354 Gene_expression of S100A7 9 0.58 7.35 0.75 5.00
89 INT182182 Positive_regulation of Positive_regulation of DCPS 4 0.08 3.32 0.7 5.00
90 INT102776 Phosphorylation of CCL2 1 0.65 1.55 0.56 5.00
91 INT242887 Positive_regulation of Gene_expression of TLR1 2 0.28 1.87 0.49 5.00
92 INT147606 Positive_regulation of TLR1 5 0.67 4.35 0.47 5.00
93 INT329817 Gene_expression of DEFB103B 1 0.01 1.18 0.43 5.00
94 INT189176 Positive_regulation of Localization of TH1L 5 0.23 2.93 0.42 5.00
95 INT232177 Gene_expression of Slc43a1 2 0.04 1.06 0.4 5.00
96 INT242895 Negative_regulation of Gene_expression of TLR1 3 0.38 0.95 0.34 5.00
97 INT195733 Phosphorylation of CCL5 2 0.10 1.04 0.33 5.00
98 INT14746 Gene_expression of Krt12 4 0.42 0.74 0.31 5.00
99 INT61903 Negative_regulation of Slc43a1 3 0.34 2.18 0.3 5.00
100 INT329823 Negative_regulation of Il12b 1 0.42 0.57 0.27 5.00
101 INT329820 Positive_regulation of Positive_regulation of CD14 1 0.19 0.84 0.23 5.00
102 INT291839 Gene_expression of Krt4 1 0.36 1.13 0.17 5.00
103 INT329819 Phosphorylation of CCL3 1 0.23 0.61 0.17 5.00
104 INT291840 Negative_regulation of Krt4 1 0.20 0.5 0.05 5.00
105 INT291838 Negative_regulation of Krt12 1 0.27 0.5 0.05 5.00
106 INT277256 Negative_regulation of Localization of Satb2 1 0.43 0.59 0.04 5.00
107 INT277259 Regulation of Satb2 1 0.45 0.72 0.03 5.00
108 INT329818 Binding of TICAM1 2 0.07 0.12 0 5.00
109 INT277253 Regulation of Localization of Satb2 1 0.45 0.61 0 5.00
110 INT277255 Transcription of Satb2 1 0.69 0.46 0 5.00
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