D:Malignant Pleural Effusion

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pChart

Disease Term
Synonyms Effusion Malignant Pleural, EFFUSIONS MALIGNANT PLEURAL, Malignant Pleural Effusions, Pleural Effusions Malignant
Documents 215
Hot Single Events 20
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Malignant Pleural Effusion. They are ordered first by their relevance to Malignant Pleural Effusion and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT84741 Binding of PBK and Cea 1 0.25 0.43 0 25.00
2 INT84739 Binding of Ighg1 and Cea 1 0.31 0.43 0 25.00
3 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
4 INT337572 TREM1 Regulation of CRP 1 0.05 0.99 0.07 5.00
5 INT353125 Negative_regulation of Binding of VEGFA and Kdr 1 0.04 5.92 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Malignant Pleural Effusion. They are ordered first by their pain relevance and then by number of times they were reported in Malignant Pleural Effusion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 99.98
2 INT13607 Binding of Ack 11 0.36 5.77 6.01 99.34
3 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69 99.28
4 INT81312 Positive_regulation of Gene_expression of Ada 2 0.50 1.58 2.26 99.28
5 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93 99.00
6 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 98.44
7 INT13907 Gene_expression of SCLC1 16 0.59 16.58 1.89 97.40
8 INT224154 Positive_regulation of TREM1 14 0.56 22.65 2.71 95.56
9 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 90.00
10 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 90.00
11 INT860 Regulation of ALB 48 0.60 25.11 8.95 89.52
12 INT313916 Negative_regulation of Protein_catabolism of ALB 1 0.18 2.86 0 87.76
13 INT14184 Positive_regulation of CPB1 23 0.55 14.38 1.73 87.56
14 INT85937 Protein_catabolism of ALB 6 0.86 4.31 0.38 87.44
15 INT17736 Gene_expression of Cfp 111 0.65 40.68 36.61 87.04
16 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 86.32
17 INT28728 Regulation of Cfp 49 0.46 13.15 21.43 85.76
18 INT179856 Gene_expression of Sdc1 4 0.75 3.88 0.03 85.68
19 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 85.00
20 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 80.60
21 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 79.84
22 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 75.00
23 INT10706 Regulation of Il6 150 0.62 93.23 62.34 75.00
24 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 75.00
25 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 75.00
26 INT164189 Gene_expression of TREM1 82 0.62 60.77 5.85 72.84
27 INT337577 Positive_regulation of Phosphorylation of TREM1 1 0.37 1.79 0.21 70.56
28 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 68.16
29 INT337579 Phosphorylation of TREM1 1 0.51 1.71 0.21 68.16
30 INT62331 Gene_expression of TNFRSF8 26 0.72 17.75 2.08 66.32
31 INT237842 Negative_regulation of TPCN1 3 0.06 0.86 0.09 56.80
32 INT8224 Gene_expression of CHGA 73 0.75 53.63 12.31 50.00
33 INT48960 Gene_expression of SCG2 16 0.68 4.41 4.33 50.00
34 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 36.64
35 INT19133 Transcription of TPSAB1 2 0.68 0.97 0.11 34.84
36 INT6852 Localization of TNF 883 0.81 705.95 270.84 31.52
37 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 31.52
38 INT91667 Localization of IL12A 39 0.74 25.51 7.36 31.12
39 INT91663 Positive_regulation of Localization of IL12A 9 0.27 5.91 1.95 31.12
40 INT122813 Binding of Krt20 11 0.32 13.77 0.88 18.56
41 INT160736 Negative_regulation of KRT7 9 0.41 10.08 0.68 12.16
42 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 11.36
43 INT8106 Gene_expression of GGT1 31 0.75 18.65 6.1 11.36
44 INT30731 Positive_regulation of Gene_expression of GGT1 8 0.49 6.55 1.15 11.36
45 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75 8.80
46 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
47 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
48 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
49 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
50 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
51 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
52 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
53 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
54 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
55 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
56 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
57 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
58 INT30 Gene_expression of Gast 158 0.78 99 41.45 5.00
59 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
60 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
61 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 5.00
62 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
63 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
64 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
65 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
66 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 5.00
67 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 5.00
68 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
69 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
70 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 5.00
71 INT3364 Binding of SGCG 87 0.47 31.93 17.24 5.00
72 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 5.00
73 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
74 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
75 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 5.00
76 INT20721 Localization of ACOT1 47 0.80 11.37 10.95 5.00
77 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 5.00
78 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
79 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
80 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 5.00
81 INT93309 Positive_regulation of CAP1 17 0.43 11.4 9.13 5.00
82 INT78320 Gene_expression of EPCAM 57 0.75 50.34 7.53 5.00
83 INT264641 Binding of AES 25 0.42 18.56 6.98 5.00
84 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85 5.00
85 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 5.00
86 INT72798 Binding of ADA 12 0.47 7.84 3.39 5.00
87 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 5.00
88 INT105884 Binding of Bcl2 19 0.35 15.67 3 5.00
89 INT8103 Binding of TP53 46 0.44 40.2 2.96 5.00
90 INT70273 Gene_expression of CALB2 9 0.75 7.85 2.54 5.00
91 INT22984 Positive_regulation of FRTS 12 0.67 5.24 2.25 5.00
92 INT12097 Regulation of GGT1 8 0.44 5.76 1.95 5.00
93 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75 5.00
94 INT64156 Negative_regulation of EPCAM 7 0.37 4.24 1.54 5.00
95 INT88934 Regulation of SPP1 9 0.54 6.94 1.47 5.00
96 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39 5.00
97 INT224151 Positive_regulation of Gene_expression of TREM1 14 0.52 13.04 1.36 5.00
98 INT39877 Positive_regulation of EPX 13 0.69 6.01 1.21 5.00
99 INT78319 Binding of EPCAM 8 0.36 10.12 1.14 5.00
100 INT171361 Regulation of Egfr 16 0.62 8.36 0.81 5.00
101 INT178489 Negative_regulation of Kdr 31 0.42 25.65 0.66 5.00
102 INT179523 Binding of Pip 4 0.14 2.61 0.64 5.00
103 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 5.00
104 INT224155 Regulation of Gene_expression of TREM1 4 0.36 3.06 0.52 5.00
105 INT153861 Binding of EPX 9 0.46 0.49 0.41 5.00
106 INT76065 Localization of MSLN 6 0.68 5.93 0.34 5.00
107 INT189445 Positive_regulation of MSLN 20 0.37 3.5 0.3 5.00
108 INT241864 Positive_regulation of Gene_expression of EPCAM 8 0.36 11.07 0.26 5.00
109 INT203001 Binding of TREM1 4 0.36 2.46 0.23 5.00
110 INT337578 Positive_regulation of Positive_regulation of TREM1 1 0.40 0.87 0.21 5.00
111 INT175416 Regulation of Negative_regulation of EGFR 4 0.60 3.94 0.14 5.00
112 INT106379 Positive_regulation of Negative_regulation of NPEPPS 2 0.06 1.84 0.14 5.00
113 INT263804 Localization of MSLNL 3 0.55 2.13 0.14 5.00
114 INT280499 Regulation of SUPV3L1 1 0.01 1.6 0.09 5.00
115 INT279191 Regulation of Negative_regulation of Egfr 2 0.45 1.44 0.05 5.00
116 INT280498 Positive_regulation of SUPV3L1 1 0.01 2.73 0.04 5.00
117 INT337576 Regulation of TREM1 1 0.22 1.43 0.03 5.00
118 INT353123 Negative_regulation of Negative_regulation of Kdr 1 0.05 0.78 0 5.00
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