D:Manic Depressive Disorder

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Disease Term
Synonyms Affective Psychosis Bipolar, Bipolar Affective Disorder, Bipolar Affective Psychosis, BIPOLAR DEPRESSION, Bipolar Disorder, Bipolar Disorders, BIPOLAR I DISORDER, Bipolar Ii Disorder, Bipolar Iii Disorder, Chronic Hypomania, Cyclothymic Disorder
Documents 1236
Hot Single Events 200
Hot Interactions 36

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Manic Depressive Disorder. They are ordered first by their relevance to Manic Depressive Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT304190 Binding of HP and ZFP91 1 0.00 2.74 0.03 100.00
2 INT304189 Binding of HP and ADHD1 1 0.02 2.59 0.07 100.00
3 INT304191 Binding of SNRPD1 and ADHD1 1 0.01 0.99 0 100.00
4 INT172205 Binding of Maoa and ADHD1 1 0.03 0.82 0.05 99.72
5 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 98.96
6 INT261394 Nsdhl Negative_regulation of nt 1 0.01 1.69 0.24 98.38
7 INT256703 Negative_regulation of Hsp90b1 Positive_regulation of Wfs1 1 0.42 0.24 0 97.96
8 INT256706 Binding of Hsp90b1 and Wfs1 1 0.43 5.02 0.2 96.64
9 INT261401 Binding of Gsk3b and ADHD1 1 0.00 1.62 0.18 96.08
10 INT261400 Binding of nt and ADHD1 1 0.00 1.69 0.18 95.40
11 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43 95.16
12 INT337812 Dgkb Regulation of Igkv4-54 1 0.07 1.27 0.08 94.72
13 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61 93.44
14 INT235870 Bdnf Regulation of Gene_expression of Slc6a4 1 0.09 0.77 0.5 89.28
15 INT304340 FKBP5 Regulation of NR3C1 1 0.05 0.71 0.37 89.20
16 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94 88.48
17 INT214370 Slc6a3 Regulation of Amph 1 0.14 0.44 0.82 86.00
18 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84 85.56
19 INT183177 Binding of FGFR3 and NUDT6 1 0.06 1.08 0.84 85.56
20 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84 85.56
21 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0 83.64
22 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0 83.64
23 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01 82.44
24 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01 82.44
25 INT256702 Binding of Wfs1 and Tmed4 1 0.01 0.61 0 81.88
26 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0 81.84
27 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69 81.36
28 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69 81.36
29 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69 81.36
30 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69 81.36
31 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69 81.36
32 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69 81.36
33 INT135203 Ighen Regulation of Gene_expression of Gmeb1 1 0.03 0.48 0.69 80.52
34 INT135215 Nfkb1 Regulation of Gene_expression of Gmeb1 1 0.01 0.48 0.69 80.52
35 INT135209 Gmeb1 Regulation of Gene_expression of Ighen 1 0.02 0.48 0.69 80.52
36 INT135214 Gmeb1 Regulation of Gene_expression of Nfkb1 1 0.01 0.48 0.69 80.52
37 INT135210 Ighen Regulation of Gene_expression of Nfkb1 1 0.01 0.47 0.68 79.20
38 INT135212 Nfkb1 Regulation of Gene_expression of Ighen 1 0.01 0.47 0.68 79.20
39 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53 79.20
40 INT256701 Binding of Hsp90aa1 and Hsp90b1 1 0.12 0.34 0 79.00
41 INT214372 Ptprq Positive_regulation of Akt1 1 0.04 0.88 1.43 77.88
42 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0 76.96
43 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0 76.96
44 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0 76.96
45 INT214369 Pik3cb Positive_regulation of Akt1 1 0.56 0.87 1.41 76.64
46 INT256707 Eif2ak3 Regulation of Gene_expression of Wfs1 1 0.10 0.78 0.03 74.64
47 INT317704 Binding of Gabrg1 and Tst 1 0.20 0.37 0.24 72.88
48 INT283841 Dlg4 Negative_regulation of Insrr 1 0.01 0.95 0.33 71.88
49 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04 71.28
50 INT262361 Binding of Pde4b and DISC1 1 0.08 0.57 0.18 69.28
51 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18 68.48
52 INT186148 Camk4 Positive_regulation of Phosphorylation of Creb1 2 0.50 1.11 0.4 68.20
53 INT256704 Xbp1 Positive_regulation of Positive_regulation of Wfs1 1 0.26 0.4 0 65.28
54 INT256705 Binding of Wfs1 and Xbp1 1 0.19 0.39 0 65.28
55 INT304577 Binding of Arntl and Clock Regulation of Gene_expression of Maoa 1 0.01 0.3 0.44 63.72
56 INT304576 Binding of Arntl and Clock 6 0.37 0.43 0.5 61.28
57 INT283840 Binding of Egf and hb 1 0.21 1.34 0.38 60.92
58 INT283842 Binding of hb and Insrr 1 0.01 1.35 0.38 60.92
59 INT235875 Bdnf Positive_regulation of Phosphorylation of Mapk1 1 0.09 0.38 0.17 59.88
60 INT235125 PDE2A Negative_regulation of Twist1 1 0.00 0.99 0.24 59.52
61 INT202254 Binding of COMT and DRD2 1 0.41 0.23 0.86 59.36
62 INT272593 Dlg4 Positive_regulation of Clc 1 0.11 0.54 0.04 58.88
63 INT272599 Dlg4 Positive_regulation of Gene_expression of Clc 1 0.11 0.54 0.04 58.88
64 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49 58.44
65 INT272598 Dlg4 Positive_regulation of Gene_expression of Gria2 1 0.03 0.53 0.04 58.16
66 INT272591 Dlg4 Positive_regulation of Gene_expression of Clybl 1 0.09 0.53 0.04 58.16
67 INT214368 Pik3cb Regulation of Ubqln1 1 0.01 0.36 0.68 58.08
68 INT258523 Positive_regulation of RAF1 Positive_regulation of Phosphorylation of GSK 1 0.19 0.64 0 57.68
69 INT272590 Dlg4 Positive_regulation of Clybl 1 0.09 0.52 0.04 56.88
70 INT251963 Binding of HSD11B1 and LIPC 1 0.15 0.35 0.03 53.28
71 INT190652 Mdk Positive_regulation of Phosphorylation of Mapk1 2 0.50 0.85 0.33 53.20
72 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13 48.04
73 INT326252 EPHB2 Positive_regulation of ras 1 0.03 0.62 0.13 48.04
74 INT337811 Gene_expression of Gsk3b Positive_regulation of Phosphorylation of Akt1 1 0.37 0.37 0.03 47.76
75 INT326246 Prkcg Positive_regulation of ras 1 0.01 0.62 0.13 47.28
76 INT326247 Prkcg Positive_regulation of Prkaca 1 0.00 0.62 0.13 47.28
77 INT326248 Prkaca Positive_regulation of ras 1 0.00 0.62 0.13 47.28
78 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17 45.56
79 INT345190 Lpar1 Regulation of Localization of Il6 1 0.05 1.19 0.04 44.84
80 INT282501 Negative_regulation of Cyp19a1 Negative_regulation of Gene_expression of Aaiq4 1 0.01 0.6 0.27 44.72
81 INT217075 Binding of Acsm3 and Slc26a4 1 0.04 2.11 0.04 38.96
82 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12 38.88
83 INT186152 Camk4 Regulation of Phosphorylation of Creb1 3 0.27 0.44 0.29 38.64
84 INT338896 Binding of JUN and Jun 1 0.01 0.06 0 38.56
85 INT290811 Binding of Mgst1 and Gsk3b 1 0.05 0 0 36.88
86 INT290809 Binding of Arntl and Gsk3b 1 0.20 0 0 36.72
87 INT289625 Binding of RS1 and PSORS1C1 1 0.02 1.15 0.17 31.60
88 INT289630 Binding of CDSN and RS1 1 0.02 1.1 0.17 31.60
89 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34 31.08
90 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84 29.08
91 INT291331 Negative_regulation of GSK3A Positive_regulation of Positive_regulation of RAF1 1 0.07 0.94 0 28.08
92 INT291335 Positive_regulation of RAF1 Positive_regulation of Phosphorylation of GSK3A 1 0.07 0.88 0 24.72
93 INT262904 Binding of IL10 and RS1 1 0.01 0.05 0 23.92
94 INT265652 Binding of CISH and MYCN 1 0.00 0.28 0.28 21.80
95 INT265651 Binding of ITGAL and MYCN 1 0.00 0.46 0.62 20.84
96 INT256700 Negative_regulation of Binding of Hsp90b1 and Wfs1 1 0.52 0 0 17.76
97 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8 16.00
98 INT354923 Binding of VDR and Uvbs1 1 0.00 0.83 0 9.56
99 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
100 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
101 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27 5.00
102 INT321477 Binding of Ubqln1 and Flvcr2 1 0.00 0.81 2.26 5.00
103 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66 5.00
104 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27 5.00
105 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2 5.00
106 INT321475 Slc6a2 Positive_regulation of Ubqln1 1 0.00 0.38 1.19 5.00
107 INT321478 Binding of Slc6a2 and Flvcr2 1 0.00 0.41 1.14 5.00
108 INT321476 Binding of Slc6a3 and Slc6a2 1 0.01 0.41 1.14 5.00
109 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13 5.00
110 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11 5.00
111 INT235709 Binding of NA and SSR1 1 0.07 0.72 1.08 5.00
112 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
113 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00
114 INT36683 Gh1 Regulation of Gnrhr 3 0.08 1.25 0.95 5.00
115 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
116 INT265649 TBK1 Negative_regulation of COMT 1 0.01 0.61 0.94 5.00
117 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84 5.00
118 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83 5.00
119 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81 5.00
120 INT235087 NOS1 Positive_regulation of Localization of ABAT 1 0.02 0.61 0.81 5.00
121 INT317705 Gad2 Regulation of Gene_expression of Gabrg1 1 0.28 0.53 0.8 5.00
122 INT164364 Binding of DRD2 and SUGT1 2 0.06 0.33 0.77 5.00
123 INT242626 Binding of Ngf and Ntrk3 3 0.15 0.27 0.77 5.00
124 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74 5.00
125 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74 5.00
126 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74 5.00
127 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74 5.00
128 INT327712 Binding of Comt and Rbm39 1 0.00 0.27 0.74 5.00
129 INT235604 Binding of Htr1a and Htr3a 1 0.01 0 0.74 5.00
130 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
131 INT261378 Nsdhl Negative_regulation of Gene_expression of Flvcr2 1 0.01 0.34 0.7 5.00
132 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69 5.00
133 INT321479 Ubqln1 Regulation of Cfp 1 0.00 0.37 0.67 5.00
134 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67 5.00
135 INT153289 Binding of Lpar1 and Gpr87 2 0.29 1.19 0.67 5.00
136 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64 5.00
137 INT242635 Binding of Bdnf and Ntrk3 3 0.25 0.98 0.64 5.00
138 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63 5.00
139 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
140 INT271194 Binding of Bdnf and Gopc 1 0.03 0.49 0.6 5.00
141 INT271192 Binding of Gopc and Gtf3a 1 0.00 0.49 0.6 5.00
142 INT345180 Binding of Lpar4 and Gpr87 1 0.06 0.69 0.59 5.00
143 INT345192 Binding of Gpr87 and Lpar5 1 0.07 0.69 0.59 5.00
144 INT261372 Gsk3b Regulation of Gene_expression of Ifi205 1 0.00 0.24 0.58 5.00
145 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57 5.00
146 INT223556 Churc1 Regulation of Cnr2 1 0.00 0.8 0.54 5.00
147 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54 5.00
148 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 5.00
149 INT228852 Th Positive_regulation of Vta1 1 0.04 0 0.53 5.00
150 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
151 INT228851 Th Positive_regulation of Mtf2 1 0.02 0 0.52 5.00
152 INT223558 Dpcr1 Regulation of Cms1 1 0.00 0.79 0.51 5.00
153 INT271191 Bdnf Regulation of Slc6a4 1 0.03 0.29 0.51 5.00
154 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49 5.00
155 INT339275 Il6 Regulation of KRT20 1 0.00 3.11 0.49 5.00
156 INT235090 Positive_regulation of GRIN1 Positive_regulation of NOS1 1 0.42 0.81 0.49 5.00
157 INT304578 Negative_regulation of HDAC9 Positive_regulation of Gene_expression of Bdnf 1 0.06 0.9 0.49 5.00
158 INT36684 Gh1 Regulation of Prl 2 0.18 1.25 0.48 5.00
159 INT172207 Binding of Drd4 and ADHD1 2 0.03 1.56 0.48 5.00
160 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
161 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48 5.00
162 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48 5.00
163 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47 5.00
164 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47 5.00
165 INT235882 Creb1 Positive_regulation of Positive_regulation of Bdnf 1 0.11 0.17 0.47 5.00
166 INT334180 Tdo2 Negative_regulation of Tbpl1 1 0.10 0.16 0.45 5.00
167 INT237452 Binding of STAR and CHTF8 1 0.00 0.48 0.45 5.00
168 INT218783 Binding of Faah and Cfp 1 0.04 0.55 0.45 5.00
169 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
170 INT228850 Dio1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.06 0 0.44 5.00
171 INT237453 Binding of STAR and MESP1 1 0.00 0.47 0.42 5.00
172 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
173 INT261374 Nsdhl Regulation of Esr2 1 0.05 0.76 0.41 5.00
174 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41 5.00
175 INT322995 Binding of ABCC1 and SSD 1 0.00 0.42 0.41 5.00
176 INT235868 Creb1 Negative_regulation of Atf6b 1 0.02 0.21 0.4 5.00
177 INT237454 Binding of STAR and GREM1 1 0.00 0.44 0.4 5.00
178 INT282505 Binding of ocd and Slc1a1 1 0.39 4.22 0.4 5.00
179 INT235887 CALM1 Regulation of Akap5 1 0.00 0 0.39 5.00
180 INT291449 Car2 Positive_regulation of SK 1 0.03 0 0.39 5.00
181 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39 5.00
182 INT235880 Binding of Mtap2 and Prkaca 1 0.07 0.41 0.38 5.00
183 INT235878 Creb1 Positive_regulation of Gene_expression of Bcl2 1 0.05 0.17 0.38 5.00
184 INT288545 Gsk3b Negative_regulation of gr 1 0.25 0.38 0.38 5.00
185 INT235083 CA2 Positive_regulation of Gene_expression of CALM1 1 0.01 0.63 0.37 5.00
186 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
187 INT235091 CALM1 Positive_regulation of NOS1 1 0.02 0.63 0.37 5.00
188 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
189 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37 5.00
190 INT352821 Tph2 Regulation of Tst 1 0.31 0.46 0.36 5.00
191 INT352822 SNRNP70 Regulation of Tst 1 0.34 0.46 0.36 5.00
192 INT153288 Binding of Lpar1 and Lpar6 2 0.31 0.78 0.36 5.00
193 INT235861 Binding of Prkaca and Akap5 1 0.20 0 0.35 5.00
194 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 5.00
195 INT242363 Binding of Il1a and Il1rn 1 0.05 0.19 0.35 5.00
196 INT214374 Pik3cb Regulation of Gene_expression of Slc6a3 1 0.37 0.3 0.35 5.00
197 INT235862 Binding of Ppp3r2 and Akap5 1 0.01 0 0.35 5.00
198 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35 5.00
199 INT235859 Binding of Prkca and Akap5 1 0.13 0 0.35 5.00
200 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Manic Depressive Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Manic Depressive Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT14043 Binding of HP 52 0.30 26.56 7.76 100.00
2 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 100.00
3 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 100.00
4 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 100.00
5 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 100.00
6 INT189236 Transcription of HP 4 0.28 3.07 0.16 100.00
7 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 100.00
8 INT304199 Negative_regulation of Positive_regulation of HP 1 0.04 1.72 0.08 100.00
9 INT255416 Regulation of Bp2 1 0.15 3.75 0.07 100.00
10 INT163539 Localization of MAFD1 1 0.47 2.07 1.06 100.00
11 INT66444 Regulation of Gene_expression of HP 4 0.45 3.48 0.15 100.00
12 INT304192 Negative_regulation of SNRPD1 2 0.15 1.44 0.14 100.00
13 INT129366 Positive_regulation of Bp2 2 0.23 1.75 0.7 100.00
14 INT150144 Gene_expression of Kcnn3 31 0.78 7.67 4.24 100.00
15 INT138257 Gene_expression of Bp2 2 0.35 1.55 0.1 100.00
16 INT255415 Binding of Bp2 1 0.12 1.58 0.04 100.00
17 INT195977 Transcription of Hsp90b1 5 0.56 1.74 1.27 100.00
18 INT1841 Negative_regulation of Hrasls 15 0.48 6.85 4.56 99.96
19 INT269279 Binding of PEA15 2 0.04 1.29 0 99.96
20 INT76743 Gene_expression of Slc6a4 55 0.76 13.53 24.9 99.96
21 INT79343 Positive_regulation of Slc6a4 10 0.50 1.77 4.05 99.96
22 INT127455 Positive_regulation of Gene_expression of Slc6a4 9 0.59 5.62 3.2 99.96
23 INT93165 Gene_expression of TRPV2 32 0.78 12.49 5.62 99.92
24 INT64052 Positive_regulation of FGFR1 26 0.52 28.47 6.36 99.92
25 INT60752 Gene_expression of ZFP91 6 0.58 2.55 0.53 99.84
26 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 99.84
27 INT27882 Gene_expression of HSP90B2P 52 0.75 36.51 9.59 99.80
28 INT65515 Binding of ocd 7 0.36 6.62 1.48 99.80
29 INT338859 Binding of DGKH 1 0.35 2.45 0.1 99.76
30 INT179760 Binding of IGKV2D-19 5 0.25 6.1 0.98 99.76
31 INT306384 Binding of Mctp1 1 0.35 0.34 0 99.76
32 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 99.74
33 INT150138 Regulation of Gene_expression of Kcnn3 1 0.54 1.96 0 99.68
34 INT139749 Regulation of Ubqln1 10 0.02 2.47 5.38 99.68
35 INT65916 Gene_expression of LAMB1 13 0.55 3.09 3.06 99.64
36 INT293259 Negative_regulation of Gene_expression of SNAP25 4 0.49 5.08 0.09 99.64
37 INT101582 Negative_regulation of SNAP25 9 0.57 4.34 2.12 99.64
38 INT35048 Localization of TNFSF14 5 0.68 3.12 0.66 99.64
39 INT256682 Gene_expression of Wfs1 1 0.74 6.63 0.25 99.60
40 INT685 Regulation of AVP 124 0.62 34.9 39.91 99.56
41 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.52
42 INT256695 Regulation of Regulation of Hsp90b1 1 0.22 1.69 0.07 99.52
43 INT304200 Positive_regulation of SNRPD1 2 0.18 0.67 0.04 99.52
44 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55 99.52
45 INT337796 Localization of Dgkb 1 0.64 1.31 0.08 99.52
46 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 99.50
47 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 99.50
48 INT311479 Gene_expression of Mllt1 4 0.58 4.92 2.39 99.48
49 INT338873 Binding of Ank3 1 0.12 0.55 0.05 99.40
50 INT304198 Positive_regulation of Gene_expression of ZFP91 1 0.05 0.85 0 99.36
51 INT323368 Binding of Dtnbp1 1 0.48 6.03 0.79 99.36
52 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 99.34
53 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 99.32
54 INT287927 Positive_regulation of THEMIS 1 0.01 3.23 0.07 99.30
55 INT91991 Negative_regulation of IGKV1-22 2 0.57 2.55 1.67 99.24
56 INT337804 Binding of Dgkb 1 0.37 9.46 1.65 99.20
57 INT135373 Regulation of Gsk3b 35 0.62 18.11 3.53 99.20
58 INT296212 Negative_regulation of CLOCK 1 0.04 0.24 0.07 99.20
59 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 99.16
60 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 99.16
61 INT111675 Regulation of TNFSF14 3 0.26 3.41 1.85 99.08
62 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 99.04
63 INT150145 Regulation of Kcnn3 2 0.45 1.11 0.71 98.98
64 INT48239 Binding of Gtf3a 52 0.33 23.14 6.45 98.96
65 INT96136 Binding of hb 12 0.34 10.21 1.68 98.96
66 INT262366 Localization of Adh4 1 0.78 1.88 1 98.96
67 INT283834 Regulation of Binding of Gtf3a 1 0.02 0.55 0.17 98.96
68 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9 98.88
69 INT128563 Binding of Mllt1 8 0.41 6.7 5.63 98.84
70 INT16887 Binding of Maoa 10 0.41 2.32 4.49 98.84
71 INT256681 Regulation of Wfs1 8 0.43 4.72 0.36 98.80
72 INT222077 Regulation of Hsp90b1 9 0.37 4.78 0.45 98.80
73 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35 98.80
74 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55 98.80
75 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4 98.80
76 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 98.76
77 INT203682 Negative_regulation of MROS 5 0.36 3.71 0.74 98.72
78 INT77691 Binding of SNRPD1 2 0.29 2.19 0.22 98.72
79 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 98.72
80 INT120335 Gene_expression of SNAP25 24 0.65 9.44 5.83 98.68
81 INT8513 Regulation of PREP 8 0.26 3.17 0.8 98.68
82 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98 98.68
83 INT34796 Positive_regulation of TNFSF14 7 0.67 4.16 2.26 98.68
84 INT338858 Regulation of HADHA 1 0.03 0.61 0.72 98.68
85 INT338863 Positive_regulation of HADHA 1 0.03 0.61 0.72 98.68
86 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 98.66
87 INT317683 Gene_expression of Gabra3 1 0.76 5.54 3.05 98.60
88 INT167285 Positive_regulation of Phosphorylation of Gsk3b 17 0.50 5.92 0.82 98.60
89 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 98.60
90 INT148491 Negative_regulation of Map3k3 3 0.02 1.71 1.18 98.60
91 INT157430 Gene_expression of Ephb6 18 0.70 8.13 7.14 98.60
92 INT317691 Gene_expression of Gabrq 1 0.69 1.42 0.77 98.60
93 INT317698 Gene_expression of Gabre 1 0.61 1.82 0.95 98.60
94 INT1893 Localization of Gh 1041 0.79 340.23 256.58 98.56
95 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 98.56
96 INT34952 Regulation of ABAT 28 0.61 6.05 14.39 98.56
97 INT168981 Negative_regulation of Disc1 2 0.52 2.93 0.7 98.52
98 INT256696 Positive_regulation of Wfs1 1 0.66 9.14 0.17 98.48
99 INT157720 Localization of ADHD1 15 0.64 15.84 1.69 98.46
100 INT304197 Localization of OSR1 1 0.08 1.25 0 98.46
101 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 98.40
102 INT79737 Positive_regulation of Ntrk1 12 0.49 3.98 6.24 98.28
103 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16 98.20
104 INT256680 Negative_regulation of Hsp90b1 4 0.47 1.43 0 98.20
105 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 98.20
106 INT304194 Transcription of LAMB1 1 0.03 1.6 0 98.16
107 INT16259 Positive_regulation of Bdnf 336 0.70 183.48 209.82 98.12
108 INT338874 Binding of Fyn 1 0.08 0.53 0.19 98.12
109 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 98.12
110 INT11732 Negative_regulation of Gtf3a 25 0.30 15.73 8.5 98.12
111 INT267577 Localization of ERC1 1 0.78 3.84 2.71 98.08
112 INT165811 Binding of Phc1 13 0.15 5.99 3.09 98.08
113 INT2330 Regulation of CB 78 0.10 20.46 32.6 98.08
114 INT61341 Positive_regulation of Prep 12 0.63 6.08 3.37 98.00
115 INT256685 Positive_regulation of Negative_regulation of Hsp90b1 1 0.41 0.24 0 97.96
116 INT207165 Gene_expression of DAK 18 0.08 9.41 2.69 97.84
117 INT105746 Regulation of ECT 22 0.39 7.6 7.47 97.80
118 INT18543 Negative_regulation of ECT 20 0.37 8.4 5.25 97.80
119 INT150825 Binding of Comt 13 0.42 6.65 6.42 97.76
120 INT317693 Gene_expression of Gpr50 1 0.69 1.49 0.77 97.76
121 INT184030 Gene_expression of Socs2 8 0.74 3.54 0.63 97.72
122 INT352818 Gene_expression of Nudt4 1 0.57 1.98 0.12 97.72
123 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88 97.68
124 INT256683 Negative_regulation of Gene_expression of Hsp90b1 2 0.35 0.67 0.07 97.68
125 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 97.68
126 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 97.60
127 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 97.60
128 INT26233 Binding of GSR 45 0.46 18.22 3.74 97.56
129 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 97.52
130 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 97.52
131 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 97.48
132 INT202715 Binding of NMS 3 0.27 6.92 0.65 97.48
133 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 97.36
134 INT179101 Gene_expression of CYP4F3 14 0.65 6.89 1.98 97.36
135 INT22891 Positive_regulation of Localization of ELANE 16 0.69 11.52 3.42 97.30
136 INT191154 Binding of HDAC9 20 0.36 14.12 1.83 97.30
137 INT101414 Gene_expression of Phc1 27 0.60 9.55 7.58 97.28
138 INT69913 Binding of ATF2 6 0.13 0.83 0.84 97.20
139 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 97.20
140 INT20964 Gene_expression of OPRK1 96 0.78 23.54 58.18 97.12
141 INT66782 Negative_regulation of Gene_expression of OPRK1 4 0.28 1.42 3.41 97.12
142 INT2609 Localization of ELANE 111 0.81 50.22 26.63 97.10
143 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 97.04
144 INT187358 Localization of Kcnn3 2 0.72 1.65 0.51 97.02
145 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13 97.00
146 INT172197 Positive_regulation of Gene_expression of Comt 12 0.69 7.61 4.06 97.00
147 INT119991 Regulation of MROS 5 0.23 4.75 0.48 96.96
148 INT16713 Binding of Creb1 53 0.48 20.24 13.06 96.92
149 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 96.88
150 INT256673 Positive_regulation of Hsp90b1 12 0.49 8.49 0.68 96.84
151 INT20881 Negative_regulation of OPRK1 20 0.43 3.73 13.37 96.84
152 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84 96.80
153 INT79658 Transcription of GSR 8 0.68 3.59 2.19 96.76
154 INT163479 Binding of Bdnf 36 0.48 25.77 14.83 96.76
155 INT24460 Localization of Drd2 12 0.73 2.96 6.46 96.76
156 INT256690 Binding of Hsp90b1 11 0.30 5.94 0.55 96.64
157 INT259191 Positive_regulation of Disc1 1 0.44 1.46 0.14 96.60
158 INT276086 Regulation of Positive_regulation of GBD3 1 0.09 1.3 0.04 96.56
159 INT178457 Positive_regulation of LIFR 12 0.56 3.98 2.9 96.40
160 INT1843 Positive_regulation of Hrasls 16 0.69 2.16 5.08 96.40
161 INT135194 Transcription of Hrasls 2 0.20 1.34 0.95 96.40
162 INT135193 Positive_regulation of Transcription of Hrasls 1 0.18 0.54 0.51 96.40
163 INT258051 Negative_regulation of Protein_catabolism of ABAT 3 0.04 1.86 1.52 96.36
164 INT258081 Protein_catabolism of ABAT 5 0.10 2.57 2.86 96.36
165 INT2396 Regulation of Maoa 25 0.62 6.04 13.27 96.20
166 INT179250 Negative_regulation of Transcription of GSR 2 0.56 1.7 0.18 96.20
167 INT64815 Binding of Jun 49 0.48 21.47 8.59 96.16
168 INT126115 Binding of Kcna7 1 0.10 1.51 0.4 96.16
169 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72 96.16
170 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 96.12
171 INT2910 Regulation of Abat 169 0.62 36.95 153.53 96.08
172 INT276085 Positive_regulation of GBD3 1 0.10 1.29 0.04 96.08
173 INT9295 Regulation of MAOB 12 0.56 3.32 3.6 95.84
174 INT256684 Positive_regulation of Gene_expression of Wfs1 1 0.66 3.62 0.16 95.64
175 INT256687 Positive_regulation of Transcription of Wfs1 1 0.44 1.95 0.09 95.64
176 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33 95.60
177 INT150432 Positive_regulation of Regulation of Yy1 1 0.19 0.39 0.35 95.56
178 INT150435 Regulation of Yy1 1 0.11 0.39 0.35 95.56
179 INT85260 Negative_regulation of ATF7IP 14 0.41 7.08 3.17 95.52
180 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 95.44
181 INT344076 Negative_regulation of Localization of Hrh1 1 0.05 0.64 0.38 95.44
182 INT344082 Negative_regulation of Localization of HTR2A 1 0.41 0.64 0.37 95.44
183 INT344080 Negative_regulation of Localization of LMOD1 1 0.03 0.64 0.34 95.44
184 INT344081 Negative_regulation of Localization of IGHD2-15 1 0.03 0.64 0.34 95.44
185 INT256693 Transcription of Wfs1 1 0.68 2.44 0.08 95.32
186 INT235835 Negative_regulation of Gene_expression of Hspg2 3 0.15 1.26 0.52 95.24
187 INT248419 Negative_regulation of Tph2 11 0.59 6.32 2.59 95.20
188 INT172198 Protein_catabolism of Comt 7 0.88 2.78 3.6 95.16
189 INT95790 Regulation of Mapk1 55 0.61 21.17 16.31 95.12
190 INT151663 Regulation of Gsk3a 3 0.16 1.03 0.54 95.12
191 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6 95.00
192 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 94.98
193 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 94.96
194 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93 94.96
195 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95 94.72
196 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52 94.68
197 INT154229 Gene_expression of ARSD 22 0.57 12.5 6.19 94.60
198 INT178458 Negative_regulation of LIFR 13 0.47 8.75 2.48 94.56
199 INT256686 Binding of Wfs1 1 0.46 0.91 0 94.56
200 INT256676 Regulation of Binding of Wfs1 1 0.43 0.35 0 94.56
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