D:Medulloblastoma

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Disease Term
Synonyms Adult Medulloblastoma, ADULT MEDULLOBLASTOMAS, ARACHNOIDAL CEREBELLAR SARCOMA CIRCUMSCRIBED, Brain Medulloblastoma, Brain Tumor Medulloblastoma, Brain Tumors Medulloblastoma, Brain Tumour Medulloblastoma, BRAIN TUMOURS MEDULLOBLASTOMA, Childhood Medulloblastoma, CHILDHOOD MEDULLOBLASTOMAS, DESMOPLASTIC MEDULLOBLASTOMA
Documents 181
Hot Single Events 113
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Medulloblastoma. They are ordered first by their relevance to Medulloblastoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0 100.00
2 INT117838 FGFR1 Regulation of FGF2 1 0.33 0.17 0.09 98.72
3 INT205961 GLI1 Positive_regulation of Negative_regulation of PTCH1 1 0.25 0.58 0 88.28
4 INT205963 GLI1 Positive_regulation of Negative_regulation of SHH 1 0.22 0.58 0 88.28
5 INT205958 GLI1 Positive_regulation of Gene_expression of PTCH1 1 0.35 0.57 0 88.28
6 INT205974 Smo Positive_regulation of GLI1 1 0.04 0.66 0 79.84
7 INT205964 SMOX Positive_regulation of GLI1 1 0.20 0.66 0 79.84
8 INT205959 Binding of SHH and SMOX 1 0.12 0.72 0 78.08
9 INT205976 Binding of Ptch1 and SMOX 1 0.21 0.72 0 78.08
10 INT205962 Binding of PTCH1 and SMOX 1 0.14 0.72 0 78.08
11 INT205975 Binding of PTCH1 and Smo 1 0.02 0.72 0 77.68
12 INT205965 Binding of Ptch1 and Smo 1 0.03 0.72 0 77.68
13 INT302822 Tnfsf10 Positive_regulation of Protein_catabolism of Psmd9 1 0.03 0.78 0.21 74.52
14 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0 74.40
15 INT264697 Binding of Hes1 and Mir199b Regulation of Notch1 1 0.00 0.86 0 74.40
16 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0 74.40
17 INT264732 Binding of Gtf3a and Mir199b 1 0.00 0.86 0 74.40
18 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0 74.40
19 INT205960 Binding of PTCH1 and SHH 1 0.21 0.71 0 74.32
20 INT205977 Binding of SHH and Ptch1 1 0.31 0.71 0 73.84
21 INT307585 Binding of EGFR and MET 1 0.11 0.52 0 72.88
22 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0 72.56
23 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0 72.56
24 INT307584 Binding of EGFR and IGF1R 1 0.03 0.52 0 72.08
25 INT307586 Binding of EGFR and CDCP1 1 0.01 0.51 0 70.88
26 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0 69.56
27 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0 69.56
28 INT302826 Negative_regulation of Binding of Il2 and Kit 1 0.01 1.28 0.14 65.36
29 INT302827 Binding of Il2 and Kit 1 0.01 1.27 0.14 65.36
30 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0 63.52
31 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0 63.16
32 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 58.56
33 INT260070 Binding of PHF2 and SPTLC1 1 0.17 1.93 0.1 57.20
34 INT279145 Binding of VHL and RNF139 1 0.30 1.87 0 56.64
35 INT300899 IGF2BP3 Positive_regulation of IGF2 1 0.37 1.06 0 46.24
36 INT279144 RNF139 Regulation of TSN 1 0.24 3.47 0 46.12
37 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28 29.32
38 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2 6.48
39 INT287893 VEGFA Positive_regulation of Localization of WISP1 1 0.03 1.23 0.1 6.48
40 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
41 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91 5.00
42 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79 5.00
43 INT302833 Gene_expression of Mir155 Negative_regulation of Gene_expression of Mmp3 1 0.03 1 0.57 5.00
44 INT302832 Tnfsf10 Positive_regulation of Akt1 1 0.04 1.63 0.56 5.00
45 INT302834 Cd4 Positive_regulation of Gene_expression of Il7 1 0.05 1.02 0.54 5.00
46 INT302838 TNF Positive_regulation of Sox18 1 0.00 0.71 0.5 5.00
47 INT302845 Il7 Positive_regulation of Gene_expression of TNF 1 0.01 0.98 0.49 5.00
48 INT302820 Stat3 Regulation of Positive_regulation of Il7 1 0.04 1.03 0.49 5.00
49 INT302823 Stat3 Regulation of Gene_expression of Il7 1 0.04 1.03 0.49 5.00
50 INT302839 MIR15A Negative_regulation of Bcl2 1 0.15 1.41 0.47 5.00
51 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47 5.00
52 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46 5.00
53 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43 5.00
54 INT302824 Mapkapk5 Positive_regulation of Phosphorylation of Hspb2 1 0.11 0.64 0.4 5.00
55 INT302825 Binding of Creb1 and Xpnpep1 1 0.00 0.64 0.39 5.00
56 INT302836 Negative_regulation of Mapk8 Negative_regulation of TNF Positive_regulation of Mir155 1 0.00 0.48 0.39 5.00
57 INT302815 TNF Positive_regulation of TNF Positive_regulation of Mir155 1 0.00 0.47 0.38 5.00
58 INT302840 Positive_regulation of TNF Positive_regulation of Mir155 1 0.01 0.47 0.38 5.00
59 INT302821 Mdk Negative_regulation of Il1 1 0.02 0.91 0.38 5.00
60 INT302843 TNF Positive_regulation of Mir155 1 0.01 0.47 0.38 5.00
61 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33 5.00
62 INT302830 Mapk14 Regulation of Mapkapk5 1 0.12 0.53 0.33 5.00
63 INT302841 Mdk Positive_regulation of Positive_regulation of TNF 1 0.01 0.35 0.33 5.00
64 INT302842 Binding of S1PR1 and S1pr1 1 0.24 0.92 0.32 5.00
65 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26 5.00
66 INT302818 Gcat Negative_regulation of Syk 1 0.00 0.53 0.24 5.00
67 INT302819 Regulation of S1pr1 Positive_regulation of Ptger2 1 0.02 0.35 0.22 5.00
68 INT302835 S1pr1 Positive_regulation of Ptger2 1 0.03 0.3 0.2 5.00
69 INT240435 JUN Positive_regulation of Gene_expression of CPOX 1 0.01 0.81 0.18 5.00
70 INT302846 Negative_regulation of Binding of S1PR1 and S1pr1 1 0.28 0.41 0.18 5.00
71 INT302553 Binding of CD8A and MID1 1 0.01 0.38 0.17 5.00
72 INT302844 Positive_regulation of Binding of S1PR1 and S1pr1 1 0.32 0.52 0.15 5.00
73 INT287890 THEMIS Regulation of Gene_expression of EPHB2 1 0.00 0.87 0.14 5.00
74 INT287883 FOS Regulation of Gene_expression of EPHB2 1 0.01 0.87 0.14 5.00
75 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13 5.00
76 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12 5.00
77 INT287881 THEMIS Positive_regulation of PRKCA 1 0.00 0.07 0.12 5.00
78 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1 5.00
79 INT239559 MSC Regulation of Gene_expression of BDNF 1 0.05 1 0.09 5.00
80 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09 5.00
81 INT287886 Negative_regulation of THEMIS Negative_regulation of PRKCA 1 0.00 1.19 0.08 5.00
82 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08 5.00
83 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08 5.00
84 INT355542 Binding of XRCC3 and BCC1 1 0.00 1.19 0.07 5.00
85 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05 5.00
86 INT287877 WNT1 Positive_regulation of Localization of WISP1 1 0.03 0.56 0.05 5.00
87 INT287889 WNT1 Positive_regulation of KRT20 1 0.00 0.56 0.05 5.00
88 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05 5.00
89 INT352623 Tpt1 Regulation of Olig2 1 0.02 0.54 0.05 5.00
90 INT352622 Olig2 Negative_regulation of Tpt1 1 0.06 0.54 0.05 5.00
91 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04 5.00
92 INT239560 MSC Regulation of Gene_expression of IFN1@ 1 0.11 0.87 0.04 5.00
93 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 5.00
94 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04 5.00
95 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04 5.00
96 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03 5.00
97 INT245075 Binding of ESR1 and NR4A1 1 0.01 1.08 0.03 5.00
98 INT245076 CXCR4 Regulation of Gene_expression of VEGFA 1 0.16 1.05 0.03 5.00
99 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 5.00
100 INT245071 Binding of CXCL12 and KDELR1 1 0.04 1.49 0 5.00
101 INT121650 Negative_regulation of Binding of CXCL12 and CXCR4 2 0.47 1.61 0 5.00
102 INT245078 FGF2 Positive_regulation of CXCR4 1 0.07 1.36 0 5.00
103 INT287892 PRDX2 Positive_regulation of HNF4A 1 0.00 0.52 0 5.00
104 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0 5.00
105 INT245073 VEGFA Positive_regulation of CXCR4 1 0.27 5.09 0 5.00
106 INT260071 Binding of FANCC and XPA 1 0.24 0.76 0 5.00
107 INT260066 Binding of PHF2 and XPA 1 0.20 1.04 0 5.00
108 INT245074 Gene_expression of VHL Negative_regulation of Gene_expression of CXCR4 1 0.31 1.84 0 5.00
109 INT245077 Binding of ESR1 and CXCL12 1 0.06 1.42 0 5.00
110 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0 5.00
111 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0 5.00
112 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0 5.00
113 INT243373 Binding of CASP8 and SERPINH1 1 0.28 1.49 0 5.00
114 INT279143 Binding of TSN and RNF139 1 0.31 0.83 0 5.00
115 INT287882 Binding of CREBBP and HNF4A 1 0.01 0.85 0 5.00
116 INT300901 Binding of IGF2 and IGF2BP1 1 0.04 0.71 0 5.00
117 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0 5.00
118 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0 5.00
119 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0 5.00
120 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 5.00
121 INT260069 Binding of FANCC and PHF2 1 0.28 0.37 0 5.00
122 INT352617 Mdm2 Positive_regulation of Positive_regulation of Trp53 1 0.20 2.56 0 5.00
123 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0 5.00
124 INT287891 Binding of CDH1 and KRT20 1 0.00 0.5 0 5.00
125 INT243374 SERPINH1 Positive_regulation of Gene_expression of CAMK4 1 0.07 1.01 0 5.00
126 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0 5.00
127 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0 5.00
128 INT300900 Binding of MYC and IGF2BP1 1 0.06 0.71 0 5.00
129 INT260073 Binding of FANCC and PTCH1 1 0.33 0.49 0 5.00
130 INT352614 Negative_regulation of Binding of Mdm2 and Trp53 1 0.19 1.16 0 5.00
131 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0 5.00
132 INT260067 Binding of PTCH1 and XPA 1 0.26 1.08 0 5.00
133 INT287874 Binding of TCF4 and TP53 1 0.02 0.54 0 5.00
134 INT352620 Gnb5 Positive_regulation of Gene_expression of Myc 1 0.01 1.09 0 5.00
135 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0 5.00
136 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0 5.00
137 INT300898 IGF2BP3 Regulation of Gene_expression of IGF2 1 0.21 0.38 0 5.00
138 INT260072 Binding of BRCA2 and FANCC 1 0.37 0.63 0 5.00
139 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0 5.00
140 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Medulloblastoma. They are ordered first by their pain relevance and then by number of times they were reported in Medulloblastoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT135299 Binding of PTCH1 10 0.48 12.16 0.84 99.98
2 INT116194 Gene_expression of Casp8 14 0.75 14.61 2.13 99.86
3 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9 99.84
4 INT183055 Gene_expression of PTCH1 10 0.77 15.54 0.26 99.76
5 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 99.40
6 INT181793 Positive_regulation of SHH 3 0.67 2.59 0.04 99.34
7 INT205972 Regulation of Gene_expression of GLI1 1 0.41 1.17 0 99.28
8 INT64173 Regulation of Gene_expression of GLI2 4 0.37 2.89 0.88 99.28
9 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.20
10 INT40753 Gene_expression of GLI1 9 0.75 5.98 0.33 98.98
11 INT264700 Gene_expression of Mir199b 1 0.12 11.67 0.28 98.84
12 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99 98.80
13 INT155896 Gene_expression of SUFU 1 0.65 1.74 0.14 98.64
14 INT256626 Regulation of Ptch2 1 0.28 1.11 0 98.56
15 INT55929 Negative_regulation of Gene_expression of Mb 5 0.42 2.37 0.62 98.40
16 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25 98.40
17 INT132519 Regulation of OPCML 4 0.54 5.18 0.25 98.40
18 INT256631 Positive_regulation of PTCH1 2 0.13 1.97 0 98.04
19 INT80017 Gene_expression of ERBB4 10 0.77 6.94 0.26 97.76
20 INT15752 Positive_regulation of Ema 15 0.40 14.57 2.34 97.60
21 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 97.60
22 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 97.40
23 INT70893 Positive_regulation of Gene_expression of IGF2 5 0.67 6.13 0.44 97.40
24 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 97.28
25 INT205969 Regulation of GLI1 4 0.41 3.09 0.04 97.24
26 INT104005 Negative_regulation of Gene_expression of DES 6 0.42 4.82 0.37 97.20
27 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 97.20
28 INT102234 Gene_expression of ESR2 17 0.65 9.29 2.3 96.84
29 INT162 Regulation of Prl 794 0.62 165.01 322.24 96.44
30 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 96.40
31 INT117660 Gene_expression of Prom1 50 0.73 39.62 3.07 96.24
32 INT63121 Binding of APC 29 0.41 23.02 3.8 96.16
33 INT66933 Binding of AXIN1 6 0.32 1.8 0.16 96.16
34 INT232510 Negative_regulation of Gene_expression of CXCR4 18 0.58 20.27 2.54 95.68
35 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 95.56
36 INT103300 Negative_regulation of Gene_expression of CRTAC1 3 0.44 2.87 0.7 95.36
37 INT20055 Gene_expression of CRTAC1 19 0.58 15.49 4.73 95.36
38 INT205968 Negative_regulation of PTCH1 2 0.58 2.35 0 95.32
39 INT232511 Regulation of PROM1 7 0.27 4.91 0.16 95.00
40 INT139366 Gene_expression of PROM1 98 0.77 67.84 3.39 95.00
41 INT300903 Negative_regulation of Localization of IGF2 1 0.40 1.45 0.05 94.88
42 INT300907 Negative_regulation of Transcription of IGF2 1 0.29 1.44 0.05 94.88
43 INT28524 Gene_expression of SMOX 3 0.58 1.99 0.26 94.48
44 INT205970 Regulation of Gene_expression of SMOX 1 0.27 0.59 0 94.48
45 INT243391 Binding of EMP3 1 0.31 1.78 0 94.44
46 INT202435 Transcription of IGF2 3 0.58 2.44 0.29 94.36
47 INT27651 Gene_expression of S100A12 45 0.76 52.25 10.51 94.28
48 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 94.24
49 INT34778 Localization of IGF2 5 0.62 4.78 0.59 93.48
50 INT1893 Localization of Gh 1041 0.79 340.23 256.58 93.20
51 INT205654 Gene_expression of FUS 9 0.32 11.53 0.16 92.96
52 INT61749 Negative_regulation of Csi 9 0.42 4.04 1.35 92.80
53 INT205967 Localization of GLI1 1 0.50 0.57 0 92.48
54 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 92.20
55 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 92.16
56 INT73627 Binding of Fap 8 0.36 11.14 0.4 92.08
57 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 91.88
58 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56 91.52
59 INT226894 Negative_regulation of Tnfsf10 14 0.57 16.64 1.87 91.32
60 INT156201 Negative_regulation of Gene_expression of MTOR 6 0.58 7.7 0.36 91.16
61 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44 91.16
62 INT223599 Regulation of MTOR 14 0.42 8.52 0.49 91.16
63 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 90.28
64 INT7980 Gene_expression of Fut4 36 0.62 13.37 3.79 90.28
65 INT48518 Gene_expression of ANPEP 51 0.78 22.88 4.18 90.28
66 INT243394 Gene_expression of EMP3 1 0.74 1.71 0 90.20
67 INT243379 Negative_regulation of Gene_expression of EMP3 1 0.56 1.78 0 90.20
68 INT205973 Binding of SHH 3 0.35 1.03 0.07 90.08
69 INT205971 Negative_regulation of Gene_expression of SMOX 1 0.25 0.57 0 90.04
70 INT213515 Binding of Shh 8 0.37 1.92 0.08 89.44
71 INT195206 Binding of BCC1 15 0.41 21.3 0.62 88.92
72 INT286107 Positive_regulation of Phosphorylation of Fap 1 0.30 3.5 0 88.88
73 INT286096 Phosphorylation of Fap 1 0.49 4.87 0 88.88
74 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 88.80
75 INT150744 Negative_regulation of Gene_expression of SYP 4 0.41 2.35 0.2 88.72
76 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 88.72
77 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 88.56
78 INT142416 Binding of Ptch1 6 0.34 4.92 0.74 87.36
79 INT51486 Negative_regulation of GNPTAB 11 0.41 8.18 1.45 87.20
80 INT139872 Regulation of Notch1 14 0.45 7.69 2.82 87.20
81 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22 87.00
82 INT23660 Negative_regulation of Fap 5 0.35 8.93 0.95 86.96
83 INT286102 Positive_regulation of Fap 5 0.30 8.58 0.04 86.96
84 INT183062 Gene_expression of SHH 12 0.65 5.28 0.21 86.72
85 INT178174 Gene_expression of Tnfsf10 78 0.76 56.83 8.64 86.20
86 INT260801 Negative_regulation of Gene_expression of Tnfsf10 7 0.42 6.49 0.54 86.20
87 INT134477 Negative_regulation of SHH 2 0.37 1.13 0.2 85.68
88 INT286095 Gene_expression of Afap1 1 0.09 2.42 0.03 85.60
89 INT94197 Negative_regulation of Phosphorylation of MAPK3 13 0.57 5.51 6.18 85.56
90 INT68565 Gene_expression of Fap 14 0.57 24.39 1.14 85.40
91 INT256625 Negative_regulation of Ptch2 1 0.42 1.27 0 85.36
92 INT256627 Regulation of Negative_regulation of Ptch2 1 0.32 1.33 0 85.36
93 INT71781 Phosphorylation of MAPK3 62 0.80 27.73 23.73 85.20
94 INT113112 Negative_regulation of CXCR4 39 0.58 28.28 5.36 84.56
95 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 84.24
96 INT155787 Localization of Csi 4 0.64 1.65 1.19 84.08
97 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 84.00
98 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 84.00
99 INT302807 Gene_expression of Ripk1 1 0.04 0.93 0.23 84.00
100 INT279147 Negative_regulation of RNF139 1 0.53 5.41 0.06 83.88
101 INT199681 Gene_expression of SERPINA5 13 0.36 15.42 1.25 83.52
102 INT163086 Positive_regulation of Notch2 2 0.31 1.29 0 83.44
103 INT103094 Binding of PPARA 308 0.47 177.26 34.75 83.36
104 INT114018 Binding of CD200 5 0.47 2.12 0.52 83.08
105 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7 83.08
106 INT260080 Negative_regulation of Gene_expression of PTCH1 1 0.58 2.09 0 82.60
107 INT351538 Binding of Prom1 8 0.38 4.44 0.49 81.84
108 INT155110 Negative_regulation of Phosphorylation of MYC 1 0.57 1.61 1.83 81.52
109 INT107685 Phosphorylation of MYC 3 0.80 2.52 2.28 81.20
110 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63 80.56
111 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41 80.56
112 INT203445 Gene_expression of Hes7 3 0.03 2.93 0.96 80.56
113 INT264723 Negative_regulation of Gene_expression of Notch1 1 0.03 0.83 0 80.56
114 INT98205 Gene_expression of PCBD1 10 0.61 14.78 7.27 78.96
115 INT120164 Gene_expression of OPCML 47 0.77 36.89 0.94 78.80
116 INT166278 Positive_regulation of PROM1 14 0.49 7.95 0.48 78.44
117 INT28525 Localization of SMOX 2 0.68 1.29 0.09 78.08
118 INT102439 Negative_regulation of SMOX 2 0.41 0.76 0.76 78.08
119 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 77.88
120 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 77.88
121 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 77.88
122 INT95636 Gene_expression of ACTG2 23 0.44 19.87 1.75 77.88
123 INT205956 Localization of Smo 1 0.06 0.71 0 77.68
124 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6 77.68
125 INT264722 Gene_expression of MIR199B 1 0.58 0.77 0 77.36
126 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52 76.20
127 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 74.44
128 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32 73.64
129 INT271929 Protein_catabolism of Psmd9 4 0.11 1.69 0.21 73.32
130 INT302788 Protein_catabolism of Tpt1 1 0.10 0.72 0.21 73.32
131 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 73.16
132 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 73.08
133 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 72.32
134 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 72.32
135 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69 72.32
136 INT188021 Positive_regulation of TP53BP1 3 0.48 1.33 0.25 72.12
137 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 71.92
138 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 71.92
139 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84 71.92
140 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1 71.72
141 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39 71.52
142 INT264708 Transcription of Hes1 1 0.67 0.83 0 70.84
143 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 70.80
144 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 70.72
145 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17 70.72
146 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 70.64
147 INT338714 Binding of PROM1 1 0.21 2.04 0 70.20
148 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 69.76
149 INT249561 Positive_regulation of Psmd1 12 0.37 7.32 5.06 69.68
150 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 69.52
151 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0 69.00
152 INT217905 Phosphorylation of CSNK1A1 3 0.54 2.14 0.05 68.64
153 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 68.36
154 INT266011 Positive_regulation of Gene_expression of Mdm2 3 0.47 4.61 0 68.36
155 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24 68.36
156 INT164645 Binding of Csi 9 0.48 4.6 2.46 68.24
157 INT9208 Positive_regulation of Csi 6 0.59 2.12 0.49 68.24
158 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65 67.92
159 INT264724 Negative_regulation of Positive_regulation of Notch1 1 0.03 0.77 0 67.92
160 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 67.72
161 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77 67.44
162 INT232799 Regulation of Gene_expression of Shh 3 0.27 1.04 0.16 67.44
163 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14 67.36
164 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13 67.36
165 INT260030 Localization of PROM1 5 0.70 4.36 0 67.00
166 INT204842 Positive_regulation of Cd44 9 0.49 6.6 0.77 66.56
167 INT226281 Regulation of TEK 1 0.60 1.33 0.11 66.40
168 INT129115 Negative_regulation of Cdkn2a 16 0.50 17.03 0.76 65.48
169 INT175517 Gene_expression of Mdm2 18 0.78 16.28 0.13 64.84
170 INT265588 Localization of Fap 4 0.47 5.67 0 63.84
171 INT68564 Binding of Fap 6 0.32 6.75 0.65 63.36
172 INT200219 Positive_regulation of VHL 18 0.50 15.38 0.67 62.88
173 INT264721 Positive_regulation of Mir199b 1 0.08 0.69 0.03 62.80
174 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 62.08
175 INT101068 Negative_regulation of CDCP1 27 0.03 17.67 3.45 61.68
176 INT218956 Regulation of RNF123 3 0.01 1.06 0.03 61.48
177 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02 60.88
178 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09 60.68
179 INT157382 Gene_expression of Csi 17 0.58 3.93 0.82 60.60
180 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29 60.56
181 INT33099 Negative_regulation of INSRR 32 0.40 13.82 9.85 60.32
182 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 58.88
183 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13 57.36
184 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 57.12
185 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23 56.80
186 INT124314 Gene_expression of IGF2BP3 7 0.77 33.13 0.97 56.64
187 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08 53.12
188 INT279159 Regulation of RNF139 1 0.56 2.98 0 51.92
189 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 51.52
190 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27 51.04
191 INT302556 Positive_regulation of Negative_regulation of MID1 1 0.03 0.56 0 49.48
192 INT165058 Negative_regulation of MID1 14 0.37 10.82 4.67 49.12
193 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64 48.72
194 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 48.40
195 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67 48.24
196 INT158641 Positive_regulation of CHEK2 5 0.35 4.15 0.37 47.92
197 INT260803 Regulation of Tnfsf10 4 0.44 5.04 0.76 47.40
198 INT188724 Gene_expression of IGLV3-1 29 0.75 20.88 0.51 46.12
199 INT284795 Positive_regulation of IGF2BP3 2 0.50 1.19 0 45.52
200 INT279151 Regulation of TSN 1 0.37 3.34 0 44.92
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