D:Melorheostosis

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pChart

Disease Term
Synonyms Melorheostoses
Documents 46
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Melorheostosis. They are ordered first by their relevance to Melorheostosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT324053 Binding of Banf1 and Lemd3 1 0.20 0.15 0 15.48
2 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03 5.00
3 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0 5.00
4 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Melorheostosis. They are ordered first by their pain relevance and then by number of times they were reported in Melorheostosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT324041 Localization of Mro 1 0.33 1.48 0 100.00
2 INT28941 Binding of ALPI 2 0.37 1.13 0.18 99.90
3 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 99.58
4 INT324046 Gene_expression of Lemd3 1 0.67 1.69 0.1 92.24
5 INT301355 Binding of Ext1 2 0.37 4.07 0.03 90.80
6 INT324047 Binding of Lemd3 1 0.48 3.18 0 90.80
7 INT107209 Negative_regulation of Positive_regulation of ALPI 1 0.33 0.45 0.1 84.80
8 INT4238 Negative_regulation of ALPI 7 0.58 3.31 0.62 84.44
9 INT140984 Regulation of Ihh 5 0.54 2.81 0.56 72.88
10 INT324044 Negative_regulation of Lemd3 1 0.43 2.86 0 66.56
11 INT324048 Positive_regulation of Negative_regulation of Lemd3 1 0.50 0.2 0 31.28
12 INT173578 Negative_regulation of CTSK 8 0.44 6.29 1.15 30.24
13 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3 27.04
14 INT324052 Binding of Banf1 1 0.18 0.48 0 26.84
15 INT324042 Regulation of Gene_expression of Ext1 1 0.45 0.12 0 17.36
16 INT301360 Gene_expression of Ext1 3 0.68 1.01 0 16.64
17 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01 16.40
18 INT130865 Positive_regulation of TNFSF11 29 0.69 12.82 2.99 16.40
19 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94 13.24
20 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
21 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
22 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
23 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
24 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
25 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
26 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 5.00
27 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06 5.00
28 INT569 Negative_regulation of C4a 13 0.42 9.48 2.85 5.00
29 INT49250 Regulation of Atp6v0d2 5 0.08 1.54 2.04 5.00
30 INT216848 Gene_expression of TCIRG1 8 0.52 2.59 1.95 5.00
31 INT259408 Gene_expression of Atp6v0d2 5 0.09 2.01 0.54 5.00
32 INT90090 Gene_expression of ADO 4 0.58 1.41 0.42 5.00
33 INT264145 Gene_expression of BSND 1 0.04 1.25 0 5.00
34 INT264146 Gene_expression of MYO7A 1 0.05 1.36 0 5.00
35 INT264147 Gene_expression of CLCN7 1 0.35 0.73 0 5.00
36 INT301358 Negative_regulation of Ext1 2 0.42 1.09 0 5.00
37 INT324043 Localization of Lemd3 1 0.75 0 0 5.00
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