D:Meningism

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Disease Term
Synonyms Dupre S Syndrome, Dupre Syndrome, Dupres Syndrome, Meningisms, Meningismus, Meningitis Like Reaction, Meningitis Like Reactions, Pseudomeningitides, Pseudomeningitis, REACTION MENINGITIS LIKE, REACTIONS MENINGITIS LIKE
Documents 186
Hot Single Events 15
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Meningism. They are ordered first by their relevance to Meningism and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36 5.00
2 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34 5.00
3 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26 5.00
4 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26 5.00
5 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26 5.00
6 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
7 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14 5.00
8 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14 5.00
9 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11 5.00
10 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 5.00
11 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05 5.00
12 INT311870 Positive_regulation of Binding of Cd8a and Mthfd1 1 0.00 0.32 0.03 5.00
13 INT232364 Bgn Negative_regulation of Agxt 1 0.02 0.65 0 5.00
14 INT311816 CD79A Positive_regulation of RAB27A 1 0.01 0.47 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Meningism. They are ordered first by their pain relevance and then by number of times they were reported in Meningism. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 99.60
2 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.44
3 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 97.28
4 INT35406 Localization of Tnf 94 0.81 64.63 31.65 95.32
5 INT19509 Localization of Ifng 55 0.78 28.25 18.67 95.32
6 INT20381 Localization of Il2 71 0.77 34.23 13.03 95.32
7 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 93.16
8 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 92.24
9 INT5344 Negative_regulation of BRD2 12 0.56 4.71 1.89 91.36
10 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 90.88
11 INT38814 Positive_regulation of Aspt1 9 0.63 6.89 3.06 89.88
12 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17 86.36
13 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 85.44
14 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 84.16
15 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 83.68
16 INT186453 Gene_expression of TAB1 6 0.65 4.83 0.35 76.96
17 INT425 Localization of PRL 455 0.81 189.64 144.8 72.40
18 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26 71.92
19 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 71.56
20 INT141706 Localization of HLA-DRB1 9 0.75 4.87 0.48 65.16
21 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 64.48
22 INT64953 Negative_regulation of HLA-DRB1 9 0.58 5.15 0.56 63.68
23 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 62.72
24 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 62.28
25 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 55.84
26 INT112968 Negative_regulation of Gnb5 5 0.34 7.79 1.81 55.84
27 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 54.16
28 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 52.48
29 INT236320 Regulation of HLA-DRB1 10 0.45 6 0.69 51.04
30 INT8159 Binding of ELL 7 0.36 12.62 0.84 50.40
31 INT187739 Binding of pf 9 0.15 3.14 0.87 50.00
32 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 48.96
33 INT16404 Regulation of CD4 54 0.61 33.05 10.29 40.08
34 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 36.00
35 INT39244 Gene_expression of TMPO 137 0.77 14.55 11.83 35.40
36 INT310442 Gene_expression of POLA1 1 0.30 0.97 0 35.40
37 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 34.88
38 INT101895 Binding of SLC17A5 5 0.36 7.08 0.18 34.84
39 INT44540 Binding of GPT 3 0.36 6.14 0.23 33.76
40 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14 32.20
41 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 31.68
42 INT36287 Binding of CD4 96 0.47 58.93 11.88 15.16
43 INT310439 Regulation of POLA1 1 0.24 2.21 0 12.84
44 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
45 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
46 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
47 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
48 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
49 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 5.00
50 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
51 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
52 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
53 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
54 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
55 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
56 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
57 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
58 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
59 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
60 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
61 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 5.00
62 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
63 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 5.00
64 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
65 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
66 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
67 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 5.00
68 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
69 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
70 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
71 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
72 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 5.00
73 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
74 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
75 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 5.00
76 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
77 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
78 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21 5.00
79 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
80 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
81 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 5.00
82 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
83 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 5.00
84 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
85 INT4809 Gene_expression of PTGDS 103 0.76 52.94 24.01 5.00
86 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
87 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
88 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 5.00
89 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
90 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
91 INT20379 Localization of Il4 85 0.73 51.22 20.55 5.00
92 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
93 INT57257 Gene_expression of IL7 69 0.62 50.24 20.36 5.00
94 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
95 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
96 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 5.00
97 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 5.00
98 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 5.00
99 INT110767 Localization of Mcpt1 43 0.68 24.3 16.74 5.00
100 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 5.00
101 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 5.00
102 INT104674 Positive_regulation of F2rl1 35 0.65 27.76 14.16 5.00
103 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
104 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 5.00
105 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 5.00
106 INT80756 Gene_expression of CD86 77 0.77 46.68 11.36 5.00
107 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
108 INT69306 Negative_regulation of TH1L 28 0.57 24.81 9.74 5.00
109 INT35366 Binding of AR 87 0.47 30.52 8.9 5.00
110 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
111 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 5.00
112 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 5.00
113 INT93914 Gene_expression of CD80 70 0.75 36.35 7.74 5.00
114 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 5.00
115 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26 5.00
116 INT14637 Negative_regulation of MBP 19 0.43 7.06 7.18 5.00
117 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 5.00
118 INT187741 Gene_expression of pf 33 0.29 12.38 7.14 5.00
119 INT39242 Negative_regulation of TMPO 29 0.58 5.15 7.04 5.00
120 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 5.00
121 INT10917 Positive_regulation of ITGAM 31 0.67 16.39 6.69 5.00
122 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 5.00
123 INT62509 Gene_expression of MCS 58 0.67 21.46 6.57 5.00
124 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 5.00
125 INT181525 Localization of Il13 24 0.66 21.51 6.55 5.00
126 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 5.00
127 INT60527 Transcription of IL10 16 0.56 13.57 6.42 5.00
128 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69 5.00
129 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 5.00
130 INT2947 Regulation of TFPI 10 0.44 5.81 4.86 5.00
131 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 5.00
132 INT151230 Positive_regulation of IL7 14 0.37 11.89 4.56 5.00
133 INT178751 Positive_regulation of TMPO 51 0.44 1.47 4.41 5.00
134 INT20372 Localization of Il5 26 0.41 18.33 4.27 5.00
135 INT73503 Positive_regulation of Gene_expression of IL13 16 0.37 14.6 4.23 5.00
136 INT4528 Negative_regulation of Sell 12 0.58 4.76 4.22 5.00
137 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2 5.00
138 INT160915 Regulation of Mmp9 16 0.35 10.25 4.07 5.00
139 INT64473 Regulation of Gene_expression of IL4 17 0.58 6.61 3.96 5.00
140 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75 5.00
141 INT9223 Localization of Ighg1 22 0.78 11.03 3.67 5.00
142 INT150395 Binding of MEFV 55 0.44 31.18 3.42 5.00
143 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15 5.00
144 INT9884 Localization of CD79A 41 0.78 21.75 3.06 5.00
145 INT39243 Regulation of TMPO 20 0.61 5.66 2.67 5.00
146 INT133029 Regulation of TLR2 18 0.56 11.31 2.62 5.00
147 INT120551 Negative_regulation of Rock2 8 0.52 2.73 2.53 5.00
148 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 5.00
149 INT177328 Positive_regulation of CXADR 9 0.48 4.29 2.27 5.00
150 INT35866 Transcription of IGHE 9 0.60 12.83 2.19 5.00
151 INT211979 Positive_regulation of Localization of Mcpt1 5 0.09 2.68 2.16 5.00
152 INT80191 Gene_expression of PTGDR2 9 0.74 4.15 2.11 5.00
153 INT173851 Localization of FN1 20 0.76 13.95 1.97 5.00
154 INT273335 Negative_regulation of Localization of Mcpt1 5 0.32 2.66 1.83 5.00
155 INT269406 Binding of TMPO 35 0.31 1.43 1.82 5.00
156 INT102751 Positive_regulation of polymerase 7 0.10 3.06 1.81 5.00
157 INT179222 Gene_expression of AMIGO2 7 0.66 7.68 1.77 5.00
158 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61 5.00
159 INT91739 Positive_regulation of MYLK 9 0.54 2.89 1.58 5.00
160 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54 5.00
161 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53 5.00
162 INT83891 Gene_expression of FUT3 20 0.61 10.49 1.41 5.00
163 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36 5.00
164 INT311848 Localization of Smr3a 1 0.14 5.85 1.04 5.00
165 INT38625 Gene_expression of ELL 8 0.58 12.53 1 5.00
166 INT45079 Binding of Ahr 21 0.44 10.07 1 5.00
167 INT38036 Gene_expression of Rac2 4 0.57 3.74 0.95 5.00
168 INT311843 Gene_expression of Smr3a 1 0.13 4.85 0.93 5.00
169 INT219358 Gene_expression of CDK5 9 0.58 5.65 0.81 5.00
170 INT157492 Transcription of Foxp3 4 0.61 1.69 0.81 5.00
171 INT311844 Negative_regulation of Irak4 1 0.29 2.88 0.72 5.00
172 INT92838 Positive_regulation of Col4a1 8 0.36 3.48 0.6 5.00
173 INT228103 Positive_regulation of Rac1 25 0.67 18.92 0.57 5.00
174 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55 5.00
175 INT311835 Regulation of Gene_expression of Smr3a 1 0.05 2.56 0.53 5.00
176 INT311846 Regulation of Localization of Smr3a 1 0.05 2.56 0.53 5.00
177 INT149861 Gene_expression of CD52 14 0.75 9.35 0.47 5.00
178 INT230879 Protein_catabolism of MCS 2 0.44 0.94 0.47 5.00
179 INT196517 Negative_regulation of Gene_expression of MCS 2 0.05 1.2 0.43 5.00
180 INT242267 Localization of Slc25a16 1 0.34 6.15 0.43 5.00
181 INT89935 Regulation of SERPINC1 5 0.37 5.11 0.41 5.00
182 INT232362 Gene_expression of Mgmt 10 0.76 8.08 0.41 5.00
183 INT171111 Regulation of Spg7 1 0.09 0.94 0.4 5.00
184 INT186121 Gene_expression of Agxt 6 0.65 2.77 0.39 5.00
185 INT53262 Gene_expression of TSS 6 0.52 1.35 0.37 5.00
186 INT221973 Negative_regulation of CDK5 4 0.57 2.26 0.36 5.00
187 INT311862 Negative_regulation of Protein_catabolism of MCS 1 0.05 0.27 0.36 5.00
188 INT202743 Localization of NANS 5 0.68 3.15 0.35 5.00
189 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34 5.00
190 INT232363 Positive_regulation of Gene_expression of Mgmt 8 0.49 6.01 0.28 5.00
191 INT225110 Regulation of Localization of FN1 2 0.21 0.93 0.27 5.00
192 INT53212 Negative_regulation of RAB27A 4 0.57 2.46 0.26 5.00
193 INT177520 Localization of EPX 3 0.47 3.3 0.26 5.00
194 INT311830 Regulation of Smr3a 1 0.05 1.18 0.25 5.00
195 INT180599 Gene_expression of EEC1 5 0.63 2.73 0.23 5.00
196 INT311832 Positive_regulation of Localization of Smr3a 1 0.09 1.25 0.21 5.00
197 INT311837 Positive_regulation of Rac2 1 0.15 1.91 0.2 5.00
198 INT199771 Localization of Ahr 8 0.70 4.86 0.2 5.00
199 INT219375 Localization of CDK5 4 0.52 2.8 0.19 5.00
200 INT299419 Transcription of Ctla4 2 0.43 0.71 0.17 5.00
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