D:Menopausal Vasomotor Symptoms

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Disease Term
Synonyms MENOPAUSAL VASOMOTOR, Vasomotor Menopausal, VASOMOTOR SYMPTOMS VMS
Documents 13
Hot Single Events 8
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Menopausal Vasomotor Symptoms. They are ordered first by their relevance to Menopausal Vasomotor Symptoms and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29 100.00
2 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29 100.00
3 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Menopausal Vasomotor Symptoms. They are ordered first by their pain relevance and then by number of times they were reported in Menopausal Vasomotor Symptoms. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT211969 Positive_regulation of Best1 34 0.11 14.92 1.44 99.84
2 INT158728 Regulation of Gene_expression of Plxna3 1 0.44 0.28 0.29 99.60
3 INT158729 Regulation of Gene_expression of Esrrb 1 0.05 0.28 0.29 99.60
4 INT158727 Positive_regulation of Gene_expression of Esrrb 1 0.06 0.28 0.29 99.46
5 INT158731 Positive_regulation of Gene_expression of Plxna3 1 0.49 0.28 0.29 99.46
6 INT158730 Gene_expression of Plxna3 4 0.65 1.82 0.29 99.40
7 INT92826 Gene_expression of Esrrb 3 0.75 1.58 1.18 99.32
8 INT211972 Regulation of Best1 18 0.33 12.04 0.67 97.84
9 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 72.68
10 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 71.28
11 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 71.28
12 INT320131 Positive_regulation of Gene_expression of Sec22b 1 0.02 0.69 0.08 64.72
13 INT37296 Binding of Esr1 117 0.43 62.51 27.33 64.56
14 INT123016 Gene_expression of Sec22b 11 0.41 5.1 2.5 63.76
15 INT197889 Binding of Sec22b 7 0.04 4.38 1.46 63.76
16 INT320132 Positive_regulation of Binding of Sec22b 1 0.02 0.73 0.09 63.76
17 INT261242 Binding of Tmed4 7 0.04 3.56 1.07 63.36
18 INT236648 Binding of Hrt1 4 0.07 5.07 0.51 57.48
19 INT20462 Binding of ESR1 210 0.44 102.7 26.34 51.44
20 INT180580 Binding of HEYL 7 0.17 4.49 1.15 42.60
21 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 15.00
22 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36 12.72
23 INT2038 Localization of Esr1 104 0.79 40.12 13.27 12.20
24 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 10.72
25 INT20461 Binding of Esr1 34 0.48 9.58 3.66 9.36
26 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 5.00
27 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 5.00
28 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 5.00
29 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
30 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 5.00
31 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
32 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 5.00
33 INT2160 Negative_regulation of Negative_regulation of LH 22 0.58 4.58 11.53 5.00
34 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 5.00
35 INT16165 Regulation of DMD 114 0.60 35.13 3.64 5.00
36 INT171998 Binding of DMD 58 0.47 38.13 3.35 5.00
37 INT10070 Negative_regulation of Fshb 13 0.42 3.48 2.5 5.00
38 INT184301 Negative_regulation of Bglap 16 0.56 11.22 1.22 5.00
39 INT38373 Positive_regulation of Ap3b1 4 0.37 1.01 0.86 5.00
40 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85 5.00
41 INT192156 Negative_regulation of Col1a1 6 0.39 3.92 0.8 5.00
42 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33 5.00
43 INT211971 Binding of Best1 16 0.22 7.73 0.33 5.00
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