D:Mesothelioma

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms MESOTHELIOMAS
Documents 67
Hot Single Events 149
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mesothelioma. They are ordered first by their relevance to Mesothelioma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0 78.64
2 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15 5.00
3 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 5.00
4 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 5.00
5 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 5.00
6 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05 5.00
7 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05 5.00
8 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05 5.00
9 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05 5.00
10 INT282294 Binding of Gpt and BPIFA4P 1 0.02 0.47 0 5.00
11 INT232918 Binding of KRT2 and KRT8 1 0.17 0.59 0 5.00
12 INT232912 Binding of KRT4 and KRT13 1 0.07 0.06 0 5.00
13 INT232910 Binding of KRT12 and KRT76 1 0.39 0.2 0 5.00
14 INT175400 RASGRP1 Positive_regulation of MAP3K5 1 0.00 1.2 0 5.00
15 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0 5.00
16 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0 5.00
17 INT232909 Binding of KRT1 and KRT9 1 0.16 0.5 0 5.00
18 INT175399 Binding of TP53 and SACM1L 1 0.00 2.37 0 5.00
19 INT181599 Binding of EWSR1 and WT1 1 0.40 0.29 0 5.00
20 INT232913 Binding of KRT3 and NBPF14 1 0.01 0.21 0 5.00
21 INT232908 Binding of KRT19 and PLAT 1 0.05 1.31 0 5.00
22 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mesothelioma. They are ordered first by their pain relevance and then by number of times they were reported in Mesothelioma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT98686 Gene_expression of Calb2 28 0.51 12.07 2.84 100.00
2 INT161471 Gene_expression of Bmi1 9 0.76 11.47 0.72 100.00
3 INT188255 Gene_expression of DKK1 19 0.60 12.69 2.39 100.00
4 INT85402 Transcription of Calb2 4 0.61 2.73 1.17 100.00
5 INT304935 Transcription of Bmi1 1 0.08 0.65 0.05 100.00
6 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82 100.00
7 INT145370 Transcription of DKK1 3 0.53 1.07 0.05 100.00
8 INT304937 Transcription of Wnt1 1 0.22 0.65 0.05 100.00
9 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
10 INT234748 Positive_regulation of MSTO1 1 0.12 2.03 0 100.00
11 INT78320 Gene_expression of EPCAM 57 0.75 50.34 7.53 99.98
12 INT189446 Gene_expression of MSLN 24 0.42 13.37 0.47 99.98
13 INT70273 Gene_expression of CALB2 9 0.75 7.85 2.54 99.94
14 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.84
15 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.84
16 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7 99.84
17 INT7904 Positive_regulation of Gene_expression of Fosl1 5 0.61 1.39 2.96 99.84
18 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8 99.84
19 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.84
20 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.84
21 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 99.84
22 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.76
23 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 99.76
24 INT234745 Gene_expression of MSTO1 1 0.13 2.66 0.16 99.74
25 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 99.72
26 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 99.72
27 INT83479 Gene_expression of KRT18 30 0.65 27.29 1 99.72
28 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 99.72
29 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 99.72
30 INT233010 Gene_expression of PERP 5 0.26 6.04 1.66 99.72
31 INT70450 Binding of KRT5 6 0.47 5.72 0.08 99.68
32 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 99.68
33 INT232960 Negative_regulation of Binding of KRT5 1 0.20 1.68 0 99.68
34 INT8103 Binding of TP53 46 0.44 40.2 2.96 99.64
35 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83 99.64
36 INT105332 Regulation of Gene_expression of IFI27 14 0.45 8.39 2.02 99.64
37 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 99.60
38 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.46
39 INT95116 Negative_regulation of PDGFA 24 0.57 19.56 1.29 99.44
40 INT76065 Localization of MSLN 6 0.68 5.93 0.34 99.40
41 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 99.40
42 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69 99.30
43 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06 99.30
44 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08 99.28
45 INT234742 Gene_expression of CCNI 1 0.58 0.44 0 99.24
46 INT304939 Gene_expression of Pdgfd 1 0.35 2.71 0.1 99.16
47 INT191952 Negative_regulation of Positive_regulation of NFKB2 4 0.11 3.31 0.76 99.10
48 INT189445 Positive_regulation of MSLN 20 0.37 3.5 0.3 99.04
49 INT225227 Gene_expression of NF2 4 0.65 4.49 0.03 99.04
50 INT13717 Positive_regulation of TYMS 3 0.40 1.64 0.49 99.04
51 INT288232 Binding of TYMS 2 0.11 2.77 0.04 99.04
52 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 98.92
53 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 98.92
54 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 98.92
55 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69 98.92
56 INT16463 Gene_expression of FTH1 15 0.65 6.28 2.66 98.90
57 INT288233 Localization of TYMS 2 0.22 2.17 0.04 98.88
58 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 98.76
59 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 98.68
60 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 98.68
61 INT3046 Gene_expression of LGALS1 20 0.75 12.48 1.11 98.68
62 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78 98.68
63 INT91463 Positive_regulation of NFKB2 19 0.40 17.7 4.6 98.66
64 INT130215 Negative_regulation of ST13P11 1 0.01 2.62 0.09 98.60
65 INT101068 Negative_regulation of CDCP1 27 0.03 17.67 3.45 98.52
66 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 98.48
67 INT242011 Localization of Cdkn2a 4 0.73 2.49 0.54 98.40
68 INT60198 Binding of JUN 54 0.48 11.56 10.27 98.36
69 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65 98.30
70 INT288231 Localization of DHFR 1 0.16 1.2 0.04 98.22
71 INT213681 Gene_expression of TYMS 9 0.33 8.96 2.45 98.16
72 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 98.14
73 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47 97.92
74 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 97.80
75 INT64233 Regulation of Trp53 35 0.62 27.11 1.53 97.48
76 INT3364 Binding of SGCG 87 0.47 31.93 17.24 97.44
77 INT172953 Binding of Trp53 33 0.37 20.76 1.41 97.00
78 INT207105 Positive_regulation of Cd63 2 0.57 1.82 0.39 96.96
79 INT252313 Positive_regulation of Cd47 4 0.22 3.95 0.87 96.72
80 INT76477 Positive_regulation of CD99 14 0.50 14.77 1.42 96.72
81 INT122740 Positive_regulation of Cd55 4 0.58 2.68 0.18 96.72
82 INT263804 Localization of MSLNL 3 0.55 2.13 0.14 96.68
83 INT133904 Positive_regulation of Ncam1 7 0.50 4.01 1.57 96.60
84 INT304938 Positive_regulation of Cd46 1 0.23 0.86 0 96.12
85 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 95.40
86 INT276530 Negative_regulation of Wt1 5 0.53 2.97 0 95.40
87 INT100046 Gene_expression of BTG2 16 0.20 10.81 1.95 95.24
88 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 94.68
89 INT304933 Gene_expression of Ncam2 1 0.27 1.13 0.1 94.68
90 INT304940 Positive_regulation of Gene_expression of Pdgfd 1 0.23 0.56 0.05 94.68
91 INT304934 Gene_expression of Abca6 1 0.29 0.56 0.05 94.68
92 INT153189 Gene_expression of Sema3a 19 0.75 14.37 4.21 94.68
93 INT249358 Gene_expression of ATXN2 1 0.37 3.59 0 94.52
94 INT213534 Positive_regulation of Ctnnd2 7 0.67 3.79 0.15 94.32
95 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 94.16
96 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 94.04
97 INT3512 Gene_expression of Igha 9 0.60 7.71 1.13 94.04
98 INT26585 Gene_expression of Vim 117 0.77 39.97 6 93.68
99 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 93.52
100 INT77427 Regulation of Negative_regulation of CPOX 17 0.26 10.03 6.15 93.52
101 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 92.88
102 INT95028 Gene_expression of Chrm4 8 0.39 2.66 0.99 92.40
103 INT190665 Gene_expression of Mixl1 4 0.35 2.54 0.2 92.40
104 INT185258 Gene_expression of Pou5f1 33 0.60 11.28 0.7 90.80
105 INT185244 Gene_expression of Sox2 27 0.65 4.71 0.61 90.80
106 INT176516 Localization of Spp1 28 0.76 19.39 1.9 89.92
107 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 89.88
108 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 89.68
109 INT242003 Negative_regulation of Tgs1 1 0.01 1.09 0 89.44
110 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 89.32
111 INT187628 Gene_expression of KRT14 15 0.75 11.54 0.1 89.20
112 INT126481 Gene_expression of Cxcr4 69 0.77 34.99 6 89.04
113 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 89.04
114 INT102547 Gene_expression of Cd68 25 0.75 14.47 5.22 89.04
115 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21 89.04
116 INT159505 Gene_expression of Tnfrsf8 2 0.12 1.35 0.11 89.04
117 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37 89.04
118 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 89.04
119 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 88.52
120 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 88.48
121 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33 88.40
122 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 87.52
123 INT304936 Negative_regulation of Cd46 1 0.28 1.04 0 87.28
124 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 86.84
125 INT37227 Regulation of EGF 19 0.45 11.16 5.17 86.84
126 INT235725 Regulation of SRC 7 0.44 4.71 0.19 86.84
127 INT288234 Regulation of PDGFD 1 0.06 0.28 0 86.84
128 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 85.68
129 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 85.68
130 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 85.40
131 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64 85.20
132 INT39877 Positive_regulation of EPX 13 0.69 6.01 1.21 84.96
133 INT153861 Binding of EPX 9 0.46 0.49 0.41 84.96
134 INT242002 Transcription of Tcf7 1 0.29 0.47 0 84.48
135 INT63348 Regulation of PECAM1 14 0.40 16.05 0.97 84.24
136 INT94713 Regulation of CD34 11 0.45 8.02 0.58 84.24
137 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68 84.04
138 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07 83.68
139 INT81194 Binding of CPOX 40 0.29 23.7 18.95 82.92
140 INT234750 Regulation of Regulation of CDKN1A 1 0.09 0.45 0 82.80
141 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94 82.48
142 INT152637 Gene_expression of UBE2B 2 0.06 1.67 0.09 81.92
143 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 81.12
144 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 81.12
145 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 81.12
146 INT91209 Binding of VIM 15 0.36 12.02 0.53 81.04
147 INT242010 Positive_regulation of Wif1 1 0.03 0.52 0 80.92
148 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 80.80
149 INT70445 Binding of KRT1 10 0.35 5.38 0.47 80.24
150 INT33520 Negative_regulation of CYC1 11 0.57 5.36 1.26 80.00
151 INT33521 Negative_regulation of Negative_regulation of CYC1 4 0.41 1.75 0.24 80.00
152 INT234743 Regulation of Negative_regulation of CYC1 1 0.01 1.01 0 80.00
153 INT234747 Negative_regulation of Regulation of CYC1 1 0.01 1.01 0 80.00
154 INT234749 Regulation of CYC1 1 0.01 0.5 0 80.00
155 INT232991 Localization of KRT5 1 0.33 1.36 0.04 79.92
156 INT172957 Negative_regulation of Mdm2 4 0.14 4.28 0.3 79.68
157 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 79.12
158 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 79.12
159 INT112003 Localization of ROS1 94 0.73 66.32 12.16 79.04
160 INT242004 Binding of Tcf7 4 0.36 2.66 0.49 79.04
161 INT190229 Gene_expression of Cd55 7 0.64 5 0.64 77.84
162 INT2065 Binding of BTG3 15 0.36 10.9 4.65 77.36
163 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 77.32
164 INT139475 Negative_regulation of DKK1 14 0.52 9.2 1.76 75.68
165 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 75.28
166 INT115502 Gene_expression of SAGE1 12 0.65 6.07 1.39 75.04
167 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08 75.00
168 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42 68.32
169 INT201549 Regulation of CD99 3 0.23 3.6 0.03 66.88
170 INT183630 Regulation of Ctnnd2 3 0.26 1.11 0.05 64.76
171 INT8068 Gene_expression of RASGRP1 29 0.54 15.1 1.37 64.00
172 INT234744 Gene_expression of NFRKB 1 0.05 0.49 0.23 64.00
173 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 64.00
174 INT234746 Regulation of MSTO1 1 0.05 0.63 0 63.60
175 INT129855 Positive_regulation of NFRKB 2 0.37 0.58 0.51 62.24
176 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23 61.12
177 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 61.12
178 INT181604 Localization of WT1 1 0.63 1.41 0.03 57.92
179 INT8063 Regulation of RASGRP1 15 0.36 9.15 1.3 55.68
180 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 51.60
181 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2 50.00
182 INT91506 Gene_expression of CYC1 6 0.65 2.7 1.37 50.00
183 INT233009 Binding of KRT13 1 0.16 1.13 0 42.24
184 INT225960 Gene_expression of KRT13 4 0.39 2.47 0 42.24
185 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 42.08
186 INT38672 Binding of KRT20 69 0.39 48.01 6.31 41.00
187 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 37.68
188 INT125627 Gene_expression of TTF1 11 0.78 12.68 0.78 37.04
189 INT216262 Gene_expression of CYGB 2 0.43 2.18 0.03 27.44
190 INT249356 Positive_regulation of Gene_expression of CYGB 1 0.26 1.14 0 27.44
191 INT164348 Positive_regulation of KRT14 5 0.49 2 0.08 21.04
192 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 20.84
193 INT232969 Positive_regulation of KRT5 1 0.27 1.24 0 20.40
194 INT232983 Negative_regulation of KRT13 1 0.26 2.44 0 19.80
195 INT146179 Gene_expression of KRT6A 23 0.75 9.39 0.52 13.84
196 INT88694 Gene_expression of WT1 17 0.75 21.88 0.56 13.44
197 INT157135 Positive_regulation of MKI67 10 0.60 7.51 0.28 11.76
198 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
199 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
200 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox