D:Metabolic Syndrome X

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Disease Term
Synonyms Cardiovascular Syndrome Metabolic, Cardiovascular Syndromes Metabolic, DYSMETABOLIC SYNDROME X, Insulin Resistance Syndrome X, Metabolic Cardiovascular Syndrome, Metabolic X Syndrome, Reaven Syndrome X, SYNDROME METABOLIC CARDIOVASCULAR, SYNDROME METABOLIC X, Syndrome X Dysmetabolic, Syndrome X Insulin Resistance
Documents 1
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Metabolic Syndrome X. They are ordered first by their relevance to Metabolic Syndrome X and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33 5.00
2 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32 5.00
3 INT230857 Negative_regulation of Binding of HSP90AA1 and NOS1 1 0.05 1.18 0.09 5.00
4 INT230856 Binding of HSP90AA1 and NOS1 1 0.04 1.17 0.09 5.00
5 INT230853 Binding of SELE and VWF 1 0.06 1.3 0.07 5.00
6 INT230854 INS Regulation of Positive_regulation of SNAP47 1 0.09 1.03 0.03 5.00
7 INT230851 INS Regulation of VCAM1 1 0.07 1.02 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Metabolic Syndrome X. They are ordered first by their pain relevance and then by number of times they were reported in Metabolic Syndrome X. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 94.32
2 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 57.24
3 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 13.52
4 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
5 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
6 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
7 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
8 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
9 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
10 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
11 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 5.00
12 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
13 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
14 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
15 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
16 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 5.00
17 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 5.00
18 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
19 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
20 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 5.00
21 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 5.00
22 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
23 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
24 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 5.00
25 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
26 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
27 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
28 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
29 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
30 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43 5.00
31 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 5.00
32 INT3076 Regulation of KNG1 52 0.60 20.39 27.89 5.00
33 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 5.00
34 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
35 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
36 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 5.00
37 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 5.00
38 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 5.00
39 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 5.00
40 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 5.00
41 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 5.00
42 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 5.00
43 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18 5.00
44 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
45 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
46 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
47 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
48 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 5.00
49 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 5.00
50 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 5.00
51 INT116433 Gene_expression of CYBB 93 0.70 50.44 11.91 5.00
52 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 5.00
53 INT398 Localization of AGT 45 0.78 16.97 11.54 5.00
54 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 5.00
55 INT48912 Localization of NOS1 52 0.77 24.14 10.92 5.00
56 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
57 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42 5.00
58 INT10184 Regulation of EDN1 44 0.62 23.78 10.06 5.00
59 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 5.00
60 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86 5.00
61 INT80549 Binding of ICAM1 53 0.47 42.76 9.72 5.00
62 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55 5.00
63 INT20664 Binding of ACE 60 0.48 35.27 9.16 5.00
64 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 5.00
65 INT63338 Regulation of Gene_expression of ICAM1 42 0.62 28.26 9.06 5.00
66 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89 5.00
67 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39 5.00
68 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15 5.00
69 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88 5.00
70 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 5.00
71 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 5.00
72 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 5.00
73 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
74 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 5.00
75 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 5.00
76 INT39047 Gene_expression of PGF 34 0.78 17.48 6 5.00
77 INT86025 Positive_regulation of Positive_regulation of PPARA 34 0.52 22.89 5.74 5.00
78 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56 5.00
79 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 5.00
80 INT116434 Positive_regulation of Gene_expression of CYBB 27 0.62 16.24 5.42 5.00
81 INT62525 Positive_regulation of SELE 38 0.70 46 5.25 5.00
82 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97 5.00
83 INT28703 Negative_regulation of TFPI 29 0.38 19.81 4.93 5.00
84 INT11064 Positive_regulation of NPR1 24 0.49 14.63 4.78 5.00
85 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 5.00
86 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26 5.00
87 INT86919 Negative_regulation of PIK3CG 40 0.57 21.16 3.97 5.00
88 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 5.00
89 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52 5.00
90 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36 5.00
91 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34 5.00
92 INT55409 Localization of VWF 17 0.80 8.99 3.06 5.00
93 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64 5.00
94 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45 5.00
95 INT17857 Negative_regulation of Gene_expression of AGT 25 0.46 21.16 2.45 5.00
96 INT104075 Positive_regulation of Gene_expression of B4GALNT1 8 0.09 7.36 2.21 5.00
97 INT48722 Negative_regulation of Gene_expression of SERPINE1 12 0.43 7.66 1.85 5.00
98 INT102893 Positive_regulation of Gene_expression of ANG 10 0.69 5.62 1.71 5.00
99 INT27293 Regulation of SOD1 21 0.53 15.73 1.55 5.00
100 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34 5.00
101 INT155992 Gene_expression of THBD 16 0.66 17 1.24 5.00
102 INT60766 Gene_expression of COL4A4 10 0.77 13.46 1.14 5.00
103 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14 5.00
104 INT79928 Positive_regulation of Localization of ALB 10 0.60 8.96 1.05 5.00
105 INT107922 Positive_regulation of Gene_expression of NOS3 17 0.60 9.32 1.04 5.00
106 INT155696 Gene_expression of PIK3CG 16 0.65 8.54 1.02 5.00
107 INT112783 Regulation of Gene_expression of SELE 6 0.40 6.82 0.87 5.00
108 INT88957 Positive_regulation of Gene_expression of VWF 12 0.42 7.34 0.75 5.00
109 INT49197 Binding of SELE 7 0.41 7.95 0.74 5.00
110 INT134754 Positive_regulation of Gene_expression of PLAT 9 0.49 4.75 0.72 5.00
111 INT9898 Positive_regulation of Gene_expression of Vwf 9 0.49 4.47 0.71 5.00
112 INT230864 Regulation of Binding of ACE 1 0.22 0.79 0.29 5.00
113 INT230862 Positive_regulation of Gene_expression of PGF 1 0.49 0.86 0.22 5.00
114 INT230830 Negative_regulation of Cacna1g 5 0.42 4.91 0.22 5.00
115 INT4415 Gene_expression of Cacna1g 6 0.65 4.64 0.22 5.00
116 INT176145 Positive_regulation of Gene_expression of PIK3CG 3 0.20 1.36 0.22 5.00
117 INT152680 Negative_regulation of THBD 3 0.29 1.87 0.21 5.00
118 INT95576 Gene_expression of GUCY2C 4 0.42 1.78 0.21 5.00
119 INT230861 Negative_regulation of Localization of NOS1 2 0.35 1.65 0.19 5.00
120 INT67181 Positive_regulation of Positive_regulation of SERPINE1 3 0.49 3.02 0.14 5.00
121 INT175642 Positive_regulation of Gene_expression of COL4A4 3 0.10 2.97 0.13 5.00
122 INT230859 Positive_regulation of Gene_expression of THBD 2 0.14 2 0.08 5.00
123 INT230866 Negative_regulation of Gene_expression of PIK3CG 2 0.28 1.37 0.07 5.00
124 INT230831 Negative_regulation of Gene_expression of Cacna1g 1 0.41 0.76 0.03 5.00
125 INT230860 Positive_regulation of SNAP47 1 0.15 1 0 5.00
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