D:Metaplasia

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pChart

Disease Term
Synonyms None
Documents 686
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Metaplasia. They are ordered first by their relevance to Metaplasia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT324015 Binding of Dclk1 and Spem1 1 0.06 0.92 0 100.00
2 INT324016 Binding of Dclk1 and Tff2 1 0.34 0.92 0 99.96
3 INT338418 Il13 Positive_regulation of Gene_expression of Il9 1 0.07 1.24 0.3 96.76
4 INT338431 IFN1@ Regulation of Localization of Il13 1 0.13 0.63 0.12 94.40
5 INT91428 CD44 Positive_regulation of Binding of MMRN1 1 0.24 0.85 0.55 93.68
6 INT221368 EGFR Regulation of Gene_expression of MUC1 1 0.05 3.82 0.06 91.56
7 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12 90.44
8 INT332252 Stat6 Positive_regulation of Gene_expression of Il13 1 0.08 1.32 0.12 90.44
9 INT226372 INCENP Negative_regulation of Gene_expression of IL5 1 0.00 1.12 0.18 87.36
10 INT279633 Binding of Ar and Abpe 1 0.01 0.99 0 85.92
11 INT188198 OSM Positive_regulation of STAT3 1 0.52 0.24 0.12 81.52
12 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 0.00 2.04 0.09 81.40
13 INT332244 Il13 Positive_regulation of Gtf3a 1 0.01 1.21 0.15 80.80
14 INT344747 ABAT Positive_regulation of Gene_expression of MUC1 1 0.04 0.6 0.05 80.52
15 INT282879 Binding of MUC5AC and RHCE 1 0.00 0.36 0 77.52
16 INT332251 Il13 Positive_regulation of Stat1 1 0.14 1.4 0.18 77.04
17 INT298055 Binding of IFN1@ and Il10 1 0.19 1.07 0.16 76.88
18 INT298056 Binding of IFN1@ and Cd4 1 0.31 1.07 0.16 76.88
19 INT188209 OSM Positive_regulation of MAPK1 1 0.35 0.47 0.27 74.64
20 INT148379 UFM1 Positive_regulation of DLL1 1 0.00 1.13 0.63 73.28
21 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13 73.12
22 INT148381 UFM1 Positive_regulation of JAG1 1 0.00 1.13 0.63 72.64
23 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 71.60
24 INT332247 Egf Positive_regulation of Stat6 1 0.13 1.23 0.19 71.28
25 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19 70.64
26 INT279632 Positive_regulation of Binding of Ar and Nr4a1 1 0.01 0.86 0.03 69.28
27 INT279634 Binding of Ar and Nr4a1 1 0.01 0.85 0.03 68.88
28 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 66.48
29 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 66.04
30 INT332253 Il13 Positive_regulation of Stat6 1 0.08 1.18 0.19 65.76
31 INT351423 Sparc Positive_regulation of Mmp2 1 0.02 1.31 0.04 60.28
32 INT175399 Binding of TP53 and SACM1L 1 0.00 2.37 0 55.44
33 INT225782 Tnfrsf11b Regulation of Enpp1 1 0.12 0.74 0 53.20
34 INT148380 PDP1 Positive_regulation of Positive_regulation of CP 1 0.12 0.64 0.44 51.04
35 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44 50.68
36 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44 50.52
37 INT179683 Binding of Col7a1 and Eln 2 0.00 3.02 0.19 42.84
38 INT321976 Dpp4 Regulation of Gcg 1 0.13 1.06 0 42.24
39 INT321977 Dpp4 Regulation of Negative_regulation of Gcg 1 0.13 1.06 0 42.24
40 INT321981 Dpp4 Regulation of Glp1r 1 0.07 1.06 0 41.20
41 INT321982 Dpp4 Regulation of Gene_expression of Glp1r 1 0.07 1.06 0 41.20
42 INT226531 Gtf3a Positive_regulation of Gene_expression of IL4 1 0.00 0.51 0 39.40
43 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56 35.60
44 INT183700 Binding of Pilra and Ducm1 1 0.00 2.35 0.53 35.12
45 INT227324 Binding of fd and Cd14 1 0.01 2.8 1.13 30.64
46 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85 28.88
47 INT351422 Mfng Negative_regulation of Jag1 1 0.06 1.29 0.07 25.04
48 INT225805 Binding of SNRNP70 and Enpp1 1 0.42 1.43 0.09 21.88
49 INT225808 SNRNP70 Regulation of Enpp1 1 0.30 0.71 0.04 21.88
50 INT225774 SNRNP70 Regulation of Binding of Insr and Enpp1 1 0.03 0.77 0.04 21.88
51 INT321979 Negative_regulation of Klk1c8 Negative_regulation of Positive_regulation of Ins1 1 0.04 0.81 0.22 20.88
52 INT321980 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1 1 0.16 0.81 0.22 20.88
53 INT267631 IRF6 Positive_regulation of Gene_expression of Il1 1 0.00 0.96 0.25 20.48
54 INT225800 Binding of Insr and Enpp1 1 0.05 0.67 0.04 14.20
55 INT69032 IL18 Positive_regulation of IFNA1 12 0.23 7.87 3.83 5.00
56 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85 5.00
57 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14 5.00
58 INT266764 TPSD1 Positive_regulation of F2RL1 Positive_regulation of Localization of SFTPA1 1 0.00 1.55 1.76 5.00
59 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63 5.00
60 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6 5.00
61 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59 5.00
62 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
63 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43 5.00
64 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29 5.00
65 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14 5.00
66 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11 5.00
67 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1 5.00
68 INT227325 Binding of IRF6 and Cd14 1 0.01 2.51 0.93 5.00
69 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92 5.00
70 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
71 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87 5.00
72 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87 5.00
73 INT226337 Binding of IL10 and IL10RA 2 0.24 2.51 0.85 5.00
74 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
75 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76 5.00
76 INT266769 IL2 Positive_regulation of Localization of IL4 1 0.00 1.03 0.72 5.00
77 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72 5.00
78 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72 5.00
79 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72 5.00
80 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72 5.00
81 INT226540 Binding of IL24 and Il20ra 1 0.00 0.97 0.71 5.00
82 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71 5.00
83 INT194618 Il17a Positive_regulation of Gene_expression of IL8 2 0.01 1.94 0.67 5.00
84 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61 5.00
85 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
86 INT226360 IL18 Positive_regulation of Gene_expression of IL4 1 0.05 2.66 0.54 5.00
87 INT226348 IL18 Positive_regulation of Gene_expression of IL13 1 0.03 2.66 0.54 5.00
88 INT171905 TNF Positive_regulation of Gene_expression of Il1 2 0.23 1.08 0.54 5.00
89 INT226517 Binding of IL19 and Il20ra 1 0.00 0.69 0.53 5.00
90 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49 5.00
91 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48 5.00
92 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46 5.00
93 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 5.00
94 INT225775 Enpp1 Positive_regulation of Ppi-rs 1 0.06 2.49 0.44 5.00
95 INT226341 S1PR1 Regulation of MBTPS1 1 0.00 0.76 0.44 5.00
96 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43 5.00
97 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43 5.00
98 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43 5.00
99 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43 5.00
100 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42 5.00
101 INT259637 Binding of Mmp12 and COPD 2 0.02 1.71 0.4 5.00
102 INT226381 S1PR1 Positive_regulation of Gene_expression of IK 1 0.00 0.64 0.38 5.00
103 INT226350 MBTPS1 Negative_regulation of Gene_expression of CD4 1 0.03 0.61 0.37 5.00
104 INT226374 Negative_regulation of Binding of CD4 and IFNA1 1 0.03 0.66 0.37 5.00
105 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 5.00
106 INT112020 Binding of Ighg1 and IgG2a 2 0.25 0.36 0.36 5.00
107 INT267595 IL12A Positive_regulation of IFN1@ 1 0.03 0.69 0.36 5.00
108 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34 5.00
109 INT267589 IL2 Positive_regulation of Gene_expression of IL12A 1 0.01 0.69 0.34 5.00
110 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34 5.00
111 INT188204 Negative_regulation of IL6 Positive_regulation of STAT3 1 0.28 0.54 0.34 5.00
112 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33 5.00
113 INT344748 NFKB2 Regulation of Gene_expression of GAD1 1 0.07 0.87 0.33 5.00
114 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32 5.00
115 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32 5.00
116 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32 5.00
117 INT332255 Ptger2 Positive_regulation of Localization of Col7a1 1 0.00 0.92 0.31 5.00
118 INT272925 Ccl2 Positive_regulation of Gene_expression of Col7a1 1 0.00 0.72 0.3 5.00
119 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
120 INT272932 Binding of Mmp9 and COPD 1 0.01 0.78 0.29 5.00
121 INT226512 Il1rl1 Positive_regulation of Jun 1 0.12 0.34 0.29 5.00
122 INT226375 INCENP Positive_regulation of Regulation of TH1L 1 0.01 0.57 0.29 5.00
123 INT272930 Positive_regulation of Binding of Mmp1a and COPD 1 0.01 0.79 0.29 5.00
124 INT272933 Binding of Mmp1a and COPD 1 0.01 0.78 0.29 5.00
125 INT272929 Positive_regulation of Binding of Mmp9 and COPD 1 0.01 0.79 0.29 5.00
126 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29 5.00
127 INT226376 INCENP Negative_regulation of Gene_expression of TH1L 1 0.00 0.61 0.29 5.00
128 INT272928 Positive_regulation of Binding of Mmp12 and COPD 1 0.01 0.79 0.29 5.00
129 INT226505 Il1rl1 Positive_regulation of Mapk8 1 0.04 0.4 0.29 5.00
130 INT226509 Il1rl1 Positive_regulation of Gene_expression of Mapk8 1 0.05 0.4 0.29 5.00
131 INT266766 Binding of PGR and GOPC 1 0.00 1.08 0.29 5.00
132 INT225794 Il1 Negative_regulation of Gene_expression of Npp 1 0.02 0.99 0.28 5.00
133 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28 5.00
134 INT225777 Il1 Negative_regulation of Npp 1 0.02 0.99 0.28 5.00
135 INT225776 Enpp1 Positive_regulation of Positive_regulation of Ppi-rs 1 0.08 1.67 0.28 5.00
136 INT225798 Il1 Negative_regulation of Gene_expression of Ppi-rs 1 0.01 1 0.28 5.00
137 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28 5.00
138 INT225796 Il1 Negative_regulation of Ppi-rs 1 0.01 1 0.28 5.00
139 INT226383 IL22 Positive_regulation of Gene_expression of INCENP 1 0.00 0.85 0.28 5.00
140 INT225784 Il1 Negative_regulation of Gene_expression of Enpp1 1 0.08 0.99 0.28 5.00
141 INT267628 IL4 Positive_regulation of IgG 1 0.00 1.42 0.27 5.00
142 INT226363 IK Positive_regulation of IL22 1 0.00 0.87 0.27 5.00
143 INT332246 Ros1 Positive_regulation of Stat1 1 0.02 0.46 0.27 5.00
144 INT267586 IL4 Positive_regulation of IGHE 1 0.00 1.42 0.27 5.00
145 INT226343 Binding of IFNA1 and IL26 1 0.02 0.18 0.26 5.00
146 INT226352 Binding of IL22 and IL22RA1 1 0.00 0.17 0.26 5.00
147 INT226342 Binding of IL20RA and IL26 1 0.00 0.18 0.26 5.00
148 INT226355 IL9 Positive_regulation of IL22 1 0.02 0.86 0.26 5.00
149 INT226537 Hand2 Positive_regulation of IL22 1 0.02 0.86 0.26 5.00
150 INT226361 Binding of IL10 and IL22RA1 1 0.00 0.17 0.26 5.00
151 INT267632 Il1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.86 0.25 5.00
152 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25 5.00
153 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25 5.00
154 INT267624 Klk1 Positive_regulation of KNG1 1 0.05 0.52 0.25 5.00
155 INT267584 TNF Positive_regulation of Gene_expression of PLA2G6 1 0.08 0.87 0.25 5.00
156 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 0.01 0.87 0.25 5.00
157 INT338424 Gtf3a Positive_regulation of Gene_expression of Ik 1 0.00 0.79 0.25 5.00
158 INT267591 CYSLTR1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.87 0.25 5.00
159 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25 5.00
160 INT266801 Dlst Positive_regulation of IL8 1 0.00 0.95 0.25 5.00
161 INT226533 Il25 Positive_regulation of Gene_expression of IL13 1 0.01 0.64 0.24 5.00
162 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24 5.00
163 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24 5.00
164 INT267623 IL6 Positive_regulation of Crp 1 0.00 1.6 0.24 5.00
165 INT225118 Foxm1 Positive_regulation of Gene_expression of MMP2 1 0.01 0.34 0.23 5.00
166 INT344746 GAD1 Regulation of Gene_expression of ABAT 1 0.19 0.75 0.23 5.00
167 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23 5.00
168 INT259623 Binding of Eln and Elane 1 0.02 1.38 0.23 5.00
169 INT225117 Foxm1 Regulation of Gene_expression of FN1 1 0.01 0.4 0.22 5.00
170 INT338421 Il2ra Negative_regulation of Gene_expression of Ik 1 0.00 1.27 0.22 5.00
171 INT338430 Cd4 Negative_regulation of Gene_expression of Ik 1 0.01 1.27 0.22 5.00
172 INT188195 GOPC Positive_regulation of MAPK1 2 0.21 0.32 0.22 5.00
173 INT318994 Il17a Regulation of Il23a 1 0.00 1.38 0.22 5.00
174 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21 5.00
175 INT188201 OSM Positive_regulation of Phosphorylation of STAT3 1 0.40 0.24 0.21 5.00
176 INT225103 ZNF630 Negative_regulation of CNR2 1 0.01 0.17 0.21 5.00
177 INT225097 ZNF630 Negative_regulation of CNR2 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.21 5.00
178 INT226511 Gene_expression of Il25 Positive_regulation of Gene_expression of Hand2 1 0.01 0.95 0.2 5.00
179 INT226373 IL19 Positive_regulation of Gene_expression of IL5 1 0.02 0.56 0.2 5.00
180 INT226336 IL19 Positive_regulation of Gene_expression of IL13 1 0.01 0.56 0.2 5.00
181 INT226379 IL19 Positive_regulation of IL5 1 0.02 0.55 0.2 5.00
182 INT226529 BTPs Negative_regulation of TH1L 1 0.05 0.22 0.2 5.00
183 INT226377 IL19 Positive_regulation of IL13 1 0.01 0.56 0.2 5.00
184 INT226514 BTPs Negative_regulation of Gene_expression of Hand2 1 0.03 0.22 0.2 5.00
185 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2 5.00
186 INT226384 INCENP Positive_regulation of IL19 1 0.00 0.58 0.2 5.00
187 INT226368 Positive_regulation of TNF Positive_regulation of Positive_regulation of IGHE 1 0.11 0.92 0.2 5.00
188 INT226338 IL19 Positive_regulation of Gene_expression of IL10 1 0.01 0.56 0.2 5.00
189 INT226333 IL21 Positive_regulation of Binding of STAT4 1 0.03 0.57 0.2 5.00
190 INT226523 BTPs Negative_regulation of Gene_expression of TH1L 1 0.05 0.22 0.2 5.00
191 INT226542 Negative_regulation of Adora2b Positive_regulation of IL19 1 0.08 0.58 0.2 5.00
192 INT226510 BTPs Negative_regulation of Hand2 1 0.03 0.22 0.2 5.00
193 INT226369 IL19 Positive_regulation of IL4 1 0.03 0.55 0.2 5.00
194 INT226525 Adora2b Positive_regulation of IL19 1 0.03 0.58 0.2 5.00
195 INT226351 IL19 Positive_regulation of IL10 1 0.01 0.55 0.2 5.00
196 INT226353 IL19 Positive_regulation of Gene_expression of IL4 1 0.03 0.56 0.2 5.00
197 INT226335 Binding of IL20 and IL20RB 1 0.03 0.29 0.19 5.00
198 INT226528 BTPs Negative_regulation of Gene_expression of IL2 1 0.04 0.22 0.19 5.00
199 INT226385 Binding of IL24 and IL22RA1 1 0.00 0.28 0.19 5.00
200 INT226362 Binding of IL20 and IL22RA1 1 0.00 0.28 0.19 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Metaplasia. They are ordered first by their pain relevance and then by number of times they were reported in Metaplasia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT324014 Binding of Spem1 1 0.06 1.37 0 100.00
2 INT324005 Positive_regulation of Spem1 1 0.08 1.37 0 100.00
3 INT324004 Regulation of Spem1 1 0.04 0.48 0 100.00
4 INT161464 Regulation of Gene_expression of Bmi1 1 0.44 3.01 0.26 100.00
5 INT160852 Regulation of CD55 5 0.16 5.28 0.56 100.00
6 INT172996 Gene_expression of MUC2 14 0.69 11.01 0.42 100.00
7 INT265433 Positive_regulation of Sprr1b 1 0.64 3.76 0.53 99.96
8 INT63361 Gene_expression of CD44 126 0.77 71.58 12.96 99.96
9 INT113980 Gene_expression of Cald1 4 0.05 7.16 0.33 99.96
10 INT91431 Positive_regulation of Gene_expression of CD44 18 0.69 9.25 1.12 99.96
11 INT113399 Positive_regulation of Pla2g4a 36 0.67 33.83 18.78 99.92
12 INT91225 Positive_regulation of Pla2g2a 22 0.57 14.77 5.01 99.92
13 INT113400 Positive_regulation of Transcription of Pla2g4a 1 0.08 0.96 0.7 99.92
14 INT38672 Binding of KRT20 69 0.39 48.01 6.31 99.92
15 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.88
16 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36 99.88
17 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 99.88
18 INT5904 Localization of MPO 62 0.81 36.37 14.64 99.88
19 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 99.86
20 INT73500 Regulation of IL13 12 0.36 10.37 3.53 99.86
21 INT226498 Regulation of IL4R 1 0.01 1.5 0.35 99.86
22 INT47540 Binding of Cp 20 0.41 15.54 7.01 99.84
23 INT161470 Regulation of Negative_regulation of Bmi1 1 0.27 1.49 0.13 99.82
24 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 99.78
25 INT236711 Gene_expression of Bcl6 15 0.30 12.98 0.58 99.78
26 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 99.74
27 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 99.70
28 INT225219 Positive_regulation of Gene_expression of Nf2 1 0.43 1.27 0.27 99.70
29 INT237743 Gene_expression of Dclk1 3 0.70 17.9 0.24 99.68
30 INT188216 Positive_regulation of Regulation of LIF 1 0.39 1.13 0.17 99.64
31 INT258953 Negative_regulation of Gene_expression of Bcl6 1 0.19 1.53 0.14 99.64
32 INT161471 Gene_expression of Bmi1 9 0.76 11.47 0.72 99.60
33 INT161473 Negative_regulation of Bmi1 1 0.42 1.49 0.13 99.60
34 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 99.56
35 INT113398 Transcription of Pla2g2a 3 0.19 1.64 1.14 99.52
36 INT50437 Regulation of LIF 6 0.44 2.12 1.53 99.52
37 INT291840 Negative_regulation of Krt4 1 0.20 0.5 0.05 99.48
38 INT291838 Negative_regulation of Krt12 1 0.27 0.5 0.05 99.48
39 INT90 Localization of Gast 400 0.81 137.67 113 99.44
40 INT69743 Gene_expression of Hmox2 36 0.78 20.77 14.26 99.42
41 INT153066 Binding of Tsku 1 0.22 1.52 0.1 99.40
42 INT202848 Gene_expression of Nf2 5 0.59 4.93 0.63 99.28
43 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 99.28
44 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 99.24
45 INT173023 Gene_expression of MUC6 13 0.69 9.77 0.46 99.24
46 INT173019 Positive_regulation of Gene_expression of MUC6 3 0.62 3.14 0.03 99.24
47 INT219108 Negative_regulation of Gene_expression of MUC5AC 11 0.31 9.74 1.08 99.18
48 INT62112 Binding of S100A8 37 0.36 17.18 3.16 99.18
49 INT155833 Gene_expression of Cma1 9 0.58 15.28 2.04 99.08
50 INT160081 Negative_regulation of Gene_expression of Sparc 1 0.56 2.75 1.47 99.08
51 INT173021 Localization of MUC5AC 14 0.70 10.73 0.91 99.06
52 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 99.04
53 INT86814 Transcription of Pla2g4a 4 0.49 2.35 2.14 99.04
54 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 99.04
55 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 99.04
56 INT69867 Gene_expression of Mip 36 0.75 24.54 10.38 99.04
57 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 99.04
58 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 99.00
59 INT12010 Gene_expression of Cp 38 0.65 20.55 7.84 98.96
60 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 98.90
61 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 98.90
62 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 98.90
63 INT82742 Gene_expression of Tff2 3 0.75 7.06 0.44 98.80
64 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 98.74
65 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06 98.60
66 INT160851 Regulation of Hgd 1 0.03 1.66 0.25 98.56
67 INT141687 Gene_expression of Muc6 3 0.76 8.21 0.61 98.52
68 INT141847 Positive_regulation of Gene_expression of Muc6 2 0.68 1.07 0.45 98.52
69 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 98.44
70 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42 98.44
71 INT288 Positive_regulation of Sct 88 0.70 32.83 24.5 98.40
72 INT35654 Gene_expression of Pgc 6 0.65 7.97 1.44 98.32
73 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06 98.32
74 INT103659 Gene_expression of Muc4 10 0.78 7.2 7.7 98.32
75 INT332259 Positive_regulation of Positive_regulation of Fgf1 1 0.18 2.33 0.23 98.32
76 INT82686 Gene_expression of Sparc 4 0.75 6.14 2.34 98.32
77 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 98.28
78 INT324006 Regulation of Gene_expression of Dclk1 1 0.21 0.95 0 98.24
79 INT163080 Gene_expression of STAT6 5 0.59 3.18 2.94 98.16
80 INT14043 Binding of HP 52 0.30 26.56 7.76 98.08
81 INT89290 Regulation of MUC1 19 0.45 10.4 0.81 98.08
82 INT4489 Positive_regulation of Muc5ac 5 0.66 5.39 1.91 98.08
83 INT114704 Positive_regulation of Fgf1 13 0.50 8.89 0.89 98.04
84 INT332258 Positive_regulation of Localization of Fgf1 1 0.18 2.32 0.23 98.04
85 INT126575 Negative_regulation of Ppi-rs 21 0.14 12.94 3.2 97.96
86 INT126577 Gene_expression of Ppi-rs 25 0.14 19.1 2.74 97.96
87 INT225753 Negative_regulation of Gene_expression of Ppi-rs 2 0.04 3.06 0.12 97.96
88 INT265438 Gene_expression of Sprr1b 1 0.72 6.76 1.33 97.92
89 INT265446 Negative_regulation of Gene_expression of Sprr1b 1 0.40 1.9 0.36 97.92
90 INT346901 Regulation of Gene_expression of DEFA5 1 0.02 1.04 0.06 97.92
91 INT163803 Regulation of Gene_expression of Cat 3 0.61 1.51 0.33 97.92
92 INT307721 Gene_expression of PALLD 1 0.76 45.01 0.89 97.76
93 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 97.64
94 INT171820 Localization of Fig4 144 0.65 27.38 20.88 97.58
95 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07 97.56
96 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47 97.56
97 INT146179 Gene_expression of KRT6A 23 0.75 9.39 0.52 97.56
98 INT252961 Localization of Fgf1 3 0.27 5.91 0.35 97.48
99 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 97.46
100 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51 97.44
101 INT153064 Positive_regulation of Regulation of Hif1a 1 0.45 1.52 0.1 97.44
102 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 97.40
103 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 97.40
104 INT105142 Positive_regulation of HSPB1 3 0.70 1.08 0.3 97.40
105 INT70215 Positive_regulation of Gene_expression of HSPB1 2 0.68 0.65 0.15 97.40
106 INT15930 Positive_regulation of Ptprs 8 0.67 7.02 3.48 97.32
107 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 97.28
108 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 97.28
109 INT83479 Gene_expression of KRT18 30 0.65 27.29 1 97.28
110 INT86639 Gene_expression of KRT16 19 0.68 12.44 7.79 97.28
111 INT135744 Positive_regulation of Id1 4 0.49 3.08 2.02 97.24
112 INT125006 Gene_expression of DEFA5 2 0.05 3.38 0.38 97.20
113 INT346907 Positive_regulation of Gene_expression of DEFA5 1 0.04 1.03 0.06 97.20
114 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 97.20
115 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 97.20
116 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 97.08
117 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8 97.08
118 INT171989 Gene_expression of Ank 8 0.78 11.76 4.36 97.08
119 INT183939 Negative_regulation of Gene_expression of Ank 2 0.43 1.81 0.47 97.08
120 INT225771 Negative_regulation of Gene_expression of Enpp1 4 0.43 3.68 0.13 97.08
121 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75 97.04
122 INT105546 Gene_expression of Tpo 2 0.76 9.29 0.28 96.96
123 INT59388 Gene_expression of Il9 16 0.66 21.79 6.42 96.76
124 INT232983 Negative_regulation of KRT13 1 0.26 2.44 0 96.72
125 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 96.60
126 INT46112 Regulation of GAD1 15 0.52 11.09 8.37 96.04
127 INT69303 Positive_regulation of Gene_expression of Il4 27 0.68 20.01 14.8 96.00
128 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38 95.96
129 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84 95.96
130 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 95.96
131 INT48217 Gene_expression of SLC4A3 22 0.75 21.12 2.17 95.96
132 INT161468 Gene_expression of Rnf2 1 0.67 3.98 0.33 95.92
133 INT168418 Positive_regulation of RCT 32 0.55 20.2 4.07 95.92
134 INT265444 Negative_regulation of Aire 1 0.37 5.68 1.3 95.84
135 INT227017 Gene_expression of KRT17 2 0.45 14.84 0.41 95.84
136 INT226430 Regulation of Localization of IL4 1 0.19 1.22 0.31 95.80
137 INT226491 Regulation of Localization of IL13 1 0.08 1.01 0.23 95.80
138 INT115842 Positive_regulation of Positive_regulation of BDNF-AS 1 0.00 1.19 0.1 95.72
139 INT70216 Gene_expression of HSPB1 8 0.78 4.81 0.64 95.64
140 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51 95.48
141 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 95.48
142 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 95.48
143 INT107641 Negative_regulation of Ighg1 19 0.39 11.44 1.54 95.48
144 INT21076 Negative_regulation of Muc5ac 8 0.42 2.48 2.78 95.36
145 INT324008 Gene_expression of Msi1 1 0.13 2.72 0.29 95.32
146 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 95.20
147 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 95.12
148 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 95.04
149 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3 94.96
150 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84 94.92
151 INT266893 Negative_regulation of Gene_expression of Cat 4 0.58 3.76 0.55 94.92
152 INT69158 Localization of IL4 48 0.71 31.3 11.98 94.92
153 INT132822 Localization of IL13 26 0.67 22.85 6.66 94.92
154 INT174478 Negative_regulation of Localization of IL4 6 0.34 3.56 1.65 94.92
155 INT226483 Negative_regulation of Localization of IL13 1 0.07 1.01 0.23 94.92
156 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 94.72
157 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 94.64
158 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 94.64
159 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 94.52
160 INT91 Positive_regulation of Localization of Gast 96 0.70 23.22 29.36 94.52
161 INT101614 Gene_expression of Dpp4 7 0.78 2.73 1.02 94.44
162 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 94.44
163 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 94.40
164 INT20373 Localization of Cd8a 28 0.64 8.22 2.07 94.24
165 INT118615 Negative_regulation of IL4 20 0.41 13.79 3.49 94.20
166 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 94.16
167 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44 94.16
168 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 94.16
169 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 93.96
170 INT181525 Localization of Il13 24 0.66 21.51 6.55 93.96
171 INT307720 Positive_regulation of Gene_expression of PALLD 1 0.68 14.69 0.21 93.88
172 INT226492 Negative_regulation of IL13 11 0.28 7.17 2.04 93.84
173 INT82955 Localization of Ddx41 4 0.53 1.08 0.06 93.84
174 INT185299 Gene_expression of PNKD 5 0.22 6.35 0 93.76
175 INT120511 Positive_regulation of Gene_expression of Cat 26 0.69 19.82 5.2 93.56
176 INT111575 Gene_expression of Muc5ac 15 0.78 7.97 1.84 93.36
177 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 93.28
178 INT282916 Positive_regulation of Transcription of MUC1 2 0.45 0.47 0.79 93.28
179 INT16194 Binding of CNR1 82 0.48 20.75 39.59 93.16
180 INT139108 Gene_expression of Hgd 3 0.38 4.69 0.6 92.92
181 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 92.92
182 INT91432 Binding of MMRN1 23 0.36 9.79 2.95 92.92
183 INT173005 Transcription of MUC1 11 0.63 10.15 2.24 92.88
184 INT105141 Regulation of Gene_expression of HSPB1 1 0.45 0.36 0.14 92.88
185 INT174979 Phosphorylation of GOPC 45 0.51 10.11 2.28 92.84
186 INT108335 Phosphorylation of EGF 17 0.80 7.3 2.09 92.76
187 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 92.60
188 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 92.48
189 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 92.40
190 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 92.40
191 INT686 Negative_regulation of Sct 35 0.59 9.59 11.32 92.40
192 INT28176 Localization of Cp 17 0.73 14.3 4.86 92.36
193 INT10916 Positive_regulation of BDNF-AS 39 0.49 25.88 5.28 92.12
194 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 92.12
195 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18 92.12
196 INT171021 Negative_regulation of IL5 18 0.41 14.74 3.39 92.12
197 INT265448 Positive_regulation of Gene_expression of Sprr1b 1 0.64 1.95 0.51 91.92
198 INT163832 Negative_regulation of Gene_expression of EGFR 50 0.59 39.71 3.45 91.92
199 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 91.84
200 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 91.76
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