D:Metastasis

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pChart

Disease Term
Synonyms METASTASES, Metastases Neoplasm, Metastasis Neoplasm, Metastatic Cancer, METASTATIC CANCERS, Metastatic Disease, METASTATIC DISEASES, Metastatic Malignant Disease, Metastatic Malignant Diseases, Metastatic Neoplasia, Metastatic Neoplasm
Documents 13146
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Metastasis. They are ordered first by their relevance to Metastasis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT307804 Ace Positive_regulation of Gene_expression of Scrib 1 0.21 2.43 0 100.00
2 INT307808 Ace Positive_regulation of Gene_expression of Ace2 1 0.22 2.43 0 100.00
3 INT325955 Ezr Regulation of Mia1 1 0.09 1.68 0 100.00
4 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16 100.00
5 INT205387 Binding of PCSK1 and DCLK1 1 0.05 1.42 0 100.00
6 INT205389 Binding of ANPEP and DCLK1 1 0.09 1.42 0 100.00
7 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 100.00
8 INT325948 Ezr Regulation of Pcx 1 0.00 0.84 0 100.00
9 INT325947 Ezr Regulation of Zfp369 1 0.00 0.84 0 100.00
10 INT333242 Bcl2l11 Positive_regulation of Gene_expression of Cxcl12 1 0.18 1.48 0.1 100.00
11 INT219421 Binding of ESR1 and MALAT1 1 0.34 0.63 0 100.00
12 INT219404 Binding of ESR1 and VEGFA 1 0.33 0.63 0 100.00
13 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0 100.00
14 INT337638 Binding of CSF1 and PSG2 1 0.11 1.52 0 100.00
15 INT351365 LPA Positive_regulation of Localization of Il6 1 0.00 1.79 0.54 100.00
16 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28 100.00
17 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28 100.00
18 INT242657 Fig4 Regulation of Ptger2 1 0.01 0.98 0 100.00
19 INT197043 Positive_regulation of Binding of PLAU and BCAS1 1 0.05 1.01 0 100.00
20 INT219407 Binding of ESR1 and PCNA 1 0.31 0.31 0 100.00
21 INT197042 Binding of PLAU and BCAS1 1 0.04 1.01 0 100.00
22 INT320880 Chi3l1 Positive_regulation of Agtr2 1 0.01 1.22 0.08 99.92
23 INT176540 Pik3cd Positive_regulation of Spp1 1 0.11 1.8 0.03 99.90
24 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 99.88
25 INT199360 Igf2 Regulation of Gene_expression of Lyve1 1 0.30 1.13 0 99.84
26 INT183861 Binding of CAV1 and CDC42EP5 1 0.03 3.21 0 99.82
27 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1 99.80
28 INT123660 F2R Positive_regulation of PAR1 2 0.10 1.96 0.22 99.76
29 INT175628 F2R Positive_regulation of F2RL1 1 0.04 1.46 0.03 99.76
30 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78 99.76
31 INT210598 PTHLH Positive_regulation of Gene_expression of TNFSF11 1 0.23 0.98 0.04 99.72
32 INT150788 ZNF398 Regulation of PTGS2 1 0.02 0.5 0.48 99.70
33 INT293408 HRAS Regulation of VEGFA 1 0.00 1.18 0.1 99.68
34 INT293409 IL8 Regulation of VEGFA 1 0.04 1.18 0.1 99.68
35 INT210595 Binding of TNF and TNFSF11 1 0.10 5.13 0.09 99.60
36 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14 99.60
37 INT224675 S100a4 Positive_regulation of Mmp3 1 0.04 0.94 0.48 99.60
38 INT245833 Plg Negative_regulation of VEGFA 1 0.05 2.21 0.04 99.60
39 INT245827 Plg Negative_regulation of Vegfa 1 0.14 1.3 0 99.60
40 INT314049 THL Negative_regulation of Gene_expression of Plau 1 0.20 2.91 0.19 99.56
41 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42 99.56
42 INT314041 THL Negative_regulation of Gene_expression of Mmp9 1 0.13 1.86 0.14 99.56
43 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8 99.56
44 INT98715 HGF Positive_regulation of Gene_expression of PTGS2 1 0.02 1.03 0.07 99.52
45 INT205158 Gene_expression of SPP1 Positive_regulation of Gene_expression of TNFSF11 1 0.11 1.08 0.08 99.48
46 INT293416 IL8 Regulation of PTHLH 1 0.04 1.18 0.1 99.44
47 INT293414 HRAS Regulation of PTHLH 1 0.00 1.18 0.1 99.44
48 INT305882 Binding of Pcx and Alms1 1 0.03 0.62 0 99.40
49 INT293410 HRAS Regulation of Localization of SPP1 1 0.00 0.8 0 99.40
50 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 99.36
51 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13 99.36
52 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 99.26
53 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14 99.26
54 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 99.24
55 INT343545 Binding of GLI2 and ROCK1 1 0.07 0.65 0.03 99.24
56 INT324058 Fn1 Positive_regulation of Furin 1 0.08 0.27 0 99.24
57 INT274469 IL12A Positive_regulation of Gene_expression of IL6 1 0.04 1.39 0.06 99.06
58 INT304186 Ang Positive_regulation of Gene_expression of VEGFA 2 0.05 2.5 0.06 99.04
59 INT293411 IL8 Regulation of IL11 1 0.03 1.17 0.1 99.00
60 INT293417 HRAS Regulation of IL11 1 0.00 1.17 0.1 99.00
61 INT314037 THL Negative_regulation of Localization of Plau 1 0.17 1.64 0.99 99.00
62 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62 99.00
63 INT314046 THL Negative_regulation of Localization of Mmp9 1 0.13 0.95 0.39 99.00
64 INT278186 Binding of TP53 and GOPC 1 0.02 0.85 0 99.00
65 INT205392 Binding of ANPEP and PCSK1 1 0.06 1.4 0 98.96
66 INT181998 TNFRSF11B Negative_regulation of Gene_expression of CTSK 1 0.07 1.98 0.27 98.96
67 INT343164 ACSL4 Regulation of Positive_regulation of ALOX15 1 0.01 1.08 0.03 98.96
68 INT301130 Binding of VEGFA and Mmp2 1 0.03 1.33 0.03 98.84
69 INT239188 Proc Positive_regulation of Akt1 3 0.01 1.72 0 98.84
70 INT325952 Gene_expression of Ezr Positive_regulation of Mapk1 1 0.02 1.69 0.15 98.72
71 INT225259 Egfr Regulation of Gene_expression of S100a7a 1 0.04 0.98 0.04 98.68
72 INT314055 THL Negative_regulation of Localization of VEGFA 1 0.04 3.73 0.11 98.60
73 INT266683 IL1B Positive_regulation of Gene_expression of PROC 1 0.00 1.62 0.11 98.40
74 INT189957 Binding of LDHA and Pttg1 1 0.05 0.35 0.08 98.32
75 INT242102 Nkx2-1 Regulation of Gene_expression of Ttf1 1 0.00 1.55 0 98.28
76 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5 98.28
77 INT106808 RECK Negative_regulation of MMP2 1 0.40 0.5 0.83 98.20
78 INT351002 Binding of Adh7 and Mrgpre 1 0.00 3.65 0 98.12
79 INT321580 Plaur Regulation of Ctsb 1 0.09 0.53 0 98.00
80 INT210707 Binding of IFNA2 and IL2 1 0.06 0.91 0 98.00
81 INT298448 Binding of SLC4A1 and Slc4a3 1 0.39 1.89 0.15 97.98
82 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 97.92
83 INT345190 Lpar1 Regulation of Localization of Il6 1 0.05 1.19 0.04 97.92
84 INT163614 POMC Regulation of MME 1 0.08 0.39 0 97.84
85 INT307814 Ace Positive_regulation of Ace Positive_regulation of Ang 1 0.30 3.05 0.15 97.80
86 INT307813 Ace Positive_regulation of Ace Positive_regulation of Agt 1 0.27 3.05 0.15 97.80
87 INT307807 Ace Positive_regulation of ras 1 0.38 3 0.15 97.80
88 INT205154 Binding of MMP9 and SPP1 1 0.25 0.45 0.05 97.80
89 INT353438 Rnd3 Negative_regulation of Rock1 1 0.26 2.08 0 97.76
90 INT343544 Negative_regulation of GLI2 Negative_regulation of Gene_expression of PTHLH 1 0.24 0.53 0.03 97.76
91 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29 97.72
92 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11 97.72
93 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 97.64
94 INT333250 Binding of Cxcr7 and Cxcl12 1 0.19 1.39 0.18 97.56
95 INT285291 TNF Positive_regulation of Gene_expression of Vcam1 2 0.10 3.1 0 97.56
96 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17 97.56
97 INT341825 Binding of TNC and PGR 1 0.14 0.63 0.09 97.56
98 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83 97.44
99 INT235434 SSB Positive_regulation of Ppara 1 0.00 1.56 0.04 97.44
100 INT321581 Plaur Regulation of Mmp9 1 0.14 0.53 0 97.36
101 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7 97.24
102 INT341826 Binding of ERBB2 and TNC 1 0.18 0.63 0.09 97.24
103 INT320887 Binding of TP63 and olt 1 0.01 2.15 0 97.24
104 INT215036 Gh Positive_regulation of Gene_expression of Trh 1 0.08 1.4 0.06 97.24
105 INT355589 Binding of EGFR and LTBP1 1 0.11 2.15 0.05 97.16
106 INT355586 Binding of LTBP1 and ANGPTL4 1 0.10 2.15 0.05 97.16
107 INT314370 Adipoq Positive_regulation of Tnfrsf11a 1 0.04 1.26 0.03 97.12
108 INT251893 Serpine1 Negative_regulation of Plau 1 0.39 0.6 0 97.08
109 INT304281 IL8 Positive_regulation of TBK1 1 0.01 2.35 0.44 97.08
110 INT325954 Binding of Cttn and Ezr 1 0.22 1.61 0.07 96.92
111 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57 96.88
112 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56 96.88
113 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56 96.88
114 INT355583 Binding of EGFR and ANGPTL4 1 0.12 2.14 0.05 96.72
115 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 96.56
116 INT307805 Ace Positive_regulation of Ang 1 0.32 1.52 0.07 96.48
117 INT307806 Ace Positive_regulation of Agt 1 0.28 1.51 0.07 96.48
118 INT175630 Binding of PCa and MMRN1 1 0.01 1.24 0 96.44
119 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8 96.40
120 INT295049 Binding of RYBP and Ad 1 0.00 0.87 0 96.28
121 INT176549 Mtv7 Positive_regulation of Spp1 1 0.26 0.86 0.03 96.20
122 INT79163 Binding of PLG and CLEC3B 2 0.29 3.18 0 96.16
123 INT337627 Binding of CLEC3B and Positive_regulation of Positive_regulation of PLG 1 0.52 1.22 0 96.16
124 INT290443 Gene_expression of TIMP2 Negative_regulation of MMP2 1 0.06 1.56 0.13 96.12
125 INT245119 Negative_regulation of RBM45 Negative_regulation of CDKN2B 1 0.01 1.43 0.08 96.08
126 INT197040 SERPINE1 Regulation of PLAU 1 0.31 0.68 0 96.08
127 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05 96.08
128 INT107909 Binding of Tnfsf11 and Tnfrsf22 1 0.01 2.12 0.11 96.04
129 INT345169 Lpar1 Negative_regulation of Dmbx1 1 0.08 2.26 0.08 96.04
130 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09 96.00
131 INT157738 GFAP Regulation of Vim 1 0.04 0.97 0.08 95.92
132 INT157737 GFAP Regulation of Eno2 1 0.08 0.97 0.08 95.92
133 INT157736 GFAP Regulation of Gfap 1 0.30 0.97 0.08 95.92
134 INT344311 PDPN Positive_regulation of Negative_regulation of VEGFA 1 0.09 0.81 0 95.92
135 INT355580 VEGFA Positive_regulation of ICAM1 1 0.09 1.39 0.09 95.88
136 INT258173 Negative_regulation of Cpox Negative_regulation of Gene_expression of Gtf3a 1 0.00 1.44 0.33 95.88
137 INT314038 THL Negative_regulation of Pik3r1 1 0.14 0.78 0.18 95.76
138 INT333255 Cxcl12 Regulation of Mcl1 1 0.12 1.12 0.15 95.48
139 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15 95.48
140 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06 95.36
141 INT150782 ZNF398 Positive_regulation of THBS3 Negative_regulation of SPARC 1 0.05 0.51 0.54 95.36
142 INT150800 THBS3 Negative_regulation of SPARC 1 0.23 0.51 0.53 95.36
143 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 95.28
144 INT344313 PDPN Positive_regulation of VEGFA 1 0.09 0.8 0 95.24
145 INT305877 Pcx Regulation of Gene_expression of Atp6v0a2 1 0.01 1.45 0.04 95.20
146 INT305885 Pcx Positive_regulation of Gene_expression of Atp6v0a2 1 0.01 1.45 0.04 95.20
147 INT79164 CLEC3B Positive_regulation of Positive_regulation of PLG 2 0.78 2.67 0 95.20
148 INT156438 Cpox Positive_regulation of Nos2 3 0.14 1.24 0.4 95.12
149 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0 95.08
150 INT350434 Negative_regulation of HSP90AA1 Positive_regulation of Gene_expression of ATF3 1 0.32 2.44 0.04 95.04
151 INT355603 Binding of CTNNA1 and Ctnnb1 1 0.00 1.07 0 94.96
152 INT156661 Binding of Pgls and Sdhb 1 0.01 1.43 0.25 94.96
153 INT245118 RBM45 Negative_regulation of CDKN2B 1 0.01 1.41 0.08 94.88
154 INT183721 HPN Positive_regulation of MYO7A 1 0.02 1.55 0 94.72
155 INT224457 TNF Positive_regulation of Pdgfa 1 0.34 1.22 0.27 94.68
156 INT110855 Pkia Negative_regulation of Egf 1 0.15 1.2 0.08 94.56
157 INT110856 TXK Negative_regulation of Egf 1 0.02 1.2 0.08 94.56
158 INT291356 CXCL12 Positive_regulation of AKT1 1 0.04 1.28 0.03 94.56
159 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16 94.56
160 INT205159 SPP1 Positive_regulation of Gene_expression of TNFSF11 1 0.11 0.8 0 94.56
161 INT183855 Binding of RHOC and ARHGEF3 1 0.02 1.8 0 94.40
162 INT348685 Positive_regulation of Mmp9 Positive_regulation of Protein_catabolism of Plau 1 0.10 0.27 0.03 94.40
163 INT233850 Zeb1 Positive_regulation of Itk 1 0.04 0.58 0.04 94.40
164 INT233854 Twist1 Positive_regulation of Itk 1 0.03 0.58 0.04 94.40
165 INT291357 CXCR4 Positive_regulation of AKT1 1 0.08 1.27 0.03 94.24
166 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13 94.24
167 INT250668 AKT1 Positive_regulation of MTOR 1 0.16 1.26 0 94.16
168 INT250663 Phosphorylation of AKT1 Positive_regulation of MTOR 1 0.16 1.26 0 94.16
169 INT246360 Binding of Cea and Muc6 1 0.00 1.09 0.12 94.16
170 INT106810 ZNF398 Positive_regulation of RECK 1 0.02 0.5 1.01 94.08
171 INT106809 ZNF398 Positive_regulation of Transcription of RECK 1 0.02 0.5 1.01 94.08
172 INT345374 VEGFA Positive_regulation of Flt4 1 0.01 2.95 0 93.88
173 INT202183 PLAU Regulation of Protein_catabolism of PLAUR 1 0.11 1.25 0.21 93.88
174 INT202184 SERPINE1 Regulation of Protein_catabolism of PLAUR 1 0.23 1.25 0.21 93.88
175 INT318211 MUC5AC Positive_regulation of Muc4 1 0.17 1.12 0.17 93.84
176 INT318188 MUC5AC Positive_regulation of MUC1 1 0.16 1.12 0.17 93.84
177 INT233849 Twist1 Positive_regulation of Snai2 1 0.07 0.58 0.04 93.84
178 INT233848 Zeb1 Positive_regulation of Snai1 1 0.07 0.58 0.04 93.84
179 INT233853 Zeb1 Positive_regulation of Snai2 1 0.09 0.58 0.04 93.84
180 INT233852 Twist1 Positive_regulation of Snai1 1 0.02 0.58 0.04 93.84
181 INT233851 Twist1 Positive_regulation of Zeb1 1 0.06 0.58 0.04 93.84
182 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07 93.80
183 INT150784 ZNF398 Positive_regulation of Localization of THBS3 1 0.07 1.02 1.07 93.80
184 INT150795 ZNF398 Positive_regulation of Localization of TIMP2 1 0.06 0.51 0.53 93.80
185 INT150790 ZNF398 Positive_regulation of Localization of MMP2 1 0.04 0.51 0.53 93.80
186 INT327406 Lox Positive_regulation of Lox Positive_regulation of Ptk2 1 0.23 2.62 0.19 93.72
187 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05 93.68
188 INT286767 Binding of Abl1 and Tusc2 1 0.54 1.04 0.03 93.68
189 INT205160 Binding of CD44 and MMP2 1 0.09 0.61 0.07 93.56
190 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72 93.40
191 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19 93.36
192 INT355588 Binding of CDH1 and CTNNA1 1 0.00 1.12 0 93.36
193 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26 93.36
194 INT246362 Binding of MUC2 and Cea 1 0.00 1.08 0.12 93.36
195 INT355364 Regulation of PTHLH Positive_regulation of Tnfsf11 1 0.04 1.51 0.19 93.32
196 INT355363 PTHLH Positive_regulation of Tnfsf11 1 0.04 1.47 0.19 93.32
197 INT175625 PAR1 Regulation of Gene_expression of MMP9 1 0.02 1.25 0.05 93.20
198 INT148531 Binding of TNFRSF11A and Tnfsf11 2 0.08 1.77 0.17 93.16
199 INT220456 Binding of VCAN and BAG6 1 0.01 3.46 0 93.12
200 INT327405 Lox Positive_regulation of Ptk2 1 0.42 1.3 0.1 93.12

Single Events

The table below shows the top 200 pain related interactions that have been reported for Metastasis. They are ordered first by their pain relevance and then by number of times they were reported in Metastasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
2 INT325930 Gene_expression of Ezr 75 0.77 59.77 4.06 100.00
3 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 100.00
4 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 100.00
5 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 100.00
6 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 100.00
7 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 100.00
8 INT88935 Positive_regulation of SPP1 36 0.70 31.07 5.49 100.00
9 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 100.00
10 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
11 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 100.00
12 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 100.00
13 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 100.00
14 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 100.00
15 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 100.00
16 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 100.00
17 INT256004 Negative_regulation of Gene_expression of Agt 2 0.34 8.07 0.13 100.00
18 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 100.00
19 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 100.00
20 INT121752 Gene_expression of IL11 54 0.62 18.05 7.16 100.00
21 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 100.00
22 INT269236 Gene_expression of D2Mit231 1 0.09 3.64 0.31 100.00
23 INT169431 Gene_expression of Vps54 17 0.21 21.76 0.96 100.00
24 INT117555 Gene_expression of PCAP 11 0.46 11.57 11.03 100.00
25 INT47311 Gene_expression of Sts 12 0.58 11.02 0.44 100.00
26 INT256008 Regulation of Gene_expression of Agt 4 0.36 5.03 0.11 100.00
27 INT267829 Regulation of Gene_expression of Scrib 2 0.20 5.89 0.19 100.00
28 INT65262 Gene_expression of Lox 47 0.74 36.59 5.65 100.00
29 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93 100.00
30 INT213917 Negative_regulation of Phosphorylation of ERBB2 9 0.54 8.68 0.91 100.00
31 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 100.00
32 INT66061 Positive_regulation of Gene_expression of AFP 6 0.70 8.67 0.81 100.00
33 INT298445 Positive_regulation of Gene_expression of SNAI1 4 0.59 5.07 0.04 100.00
34 INT22383 Binding of IL2 59 0.48 39.06 8.56 100.00
35 INT108326 Positive_regulation of Gene_expression of Scrib 5 0.26 9.02 0.36 100.00
36 INT9384 Positive_regulation of Positive_regulation of LDHA 3 0.50 5.5 0.52 100.00
37 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14 100.00
38 INT8713 Regulation of Tac1 56 0.60 25.29 45.94 100.00
39 INT307791 Negative_regulation of Gene_expression of Scrib 1 0.19 2.55 0 100.00
40 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 100.00
41 INT261715 Positive_regulation of Wisp1 1 0.02 1.89 0.03 100.00
42 INT44872 Localization of Sts 5 0.64 5.2 0.2 100.00
43 INT280235 Localization of Me2 1 0.01 1.67 0 100.00
44 INT96351 Negative_regulation of Gene_expression of DAB2 1 0.50 6.09 0.3 100.00
45 INT201466 Positive_regulation of Gene_expression of CCNE2 13 0.20 8.62 1.26 100.00
46 INT209537 Gene_expression of Muc4 16 0.74 6.54 0.31 100.00
47 INT113568 Protein_catabolism of PLAU 5 0.94 4.79 0.57 100.00
48 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 100.00
49 INT176521 Positive_regulation of Lepr 8 0.07 6.6 0.03 100.00
50 INT103244 Protein_catabolism of MMP9 12 0.72 11.81 2.01 100.00
51 INT261717 Negative_regulation of Binding of Dbm2 1 0.33 1.46 0 100.00
52 INT261718 Binding of Dbm2 1 0.28 1.46 0 100.00
53 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68 100.00
54 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4 100.00
55 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 100.00
56 INT169189 Gene_expression of Adam10 1 0.76 7.31 1.55 100.00
57 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35 100.00
58 INT189337 Localization of Rpa1 3 0.12 1.47 0 100.00
59 INT173877 Positive_regulation of Gene_expression of INCENP 14 0.08 7.83 1.28 100.00
60 INT66002 Binding of LAMC2 9 0.47 4.5 2.54 100.00
61 INT180975 Gene_expression of IL19 20 0.75 9.12 1.13 100.00
62 INT111383 Positive_regulation of Gene_expression of Sts 2 0.40 1.08 0 100.00
63 INT203724 Binding of Col18a1 3 0.20 4.69 0.62 100.00
64 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79 100.00
65 INT106667 Gene_expression of NDRG1 18 0.70 9.96 5.14 100.00
66 INT258463 Negative_regulation of Lvs 6 0.18 4.56 0.08 100.00
67 INT58679 Gene_expression of Odc1 13 0.78 9.55 0.45 100.00
68 INT86437 Binding of IL6 154 0.48 121.22 29.3 100.00
69 INT110925 Positive_regulation of Positive_regulation of JUN 14 0.49 6.22 1.98 100.00
70 INT290473 Positive_regulation of Regulation of PLAUR 1 0.24 1.71 0 100.00
71 INT233555 Regulation of Cxcl12 2 0.43 4.12 0.13 100.00
72 INT14043 Binding of HP 52 0.30 26.56 7.76 100.00
73 INT350524 Localization of Crlf1 1 0.24 0.68 0 100.00
74 INT142753 Gene_expression of Lcn2 28 0.76 10.03 3.62 100.00
75 INT95118 Negative_regulation of Gene_expression of PDGFA 4 0.54 5.03 0.76 100.00
76 INT166379 Gene_expression of Araf 11 0.49 5.2 0.9 100.00
77 INT328097 Positive_regulation of MBOAT7 1 0.02 3.57 0.38 100.00
78 INT269234 Regulation of Gene_expression of D2Mit231 1 0.05 0.37 0.04 100.00
79 INT336696 Negative_regulation of Gene_expression of Sts 1 0.19 1.06 0.03 100.00
80 INT64801 Negative_regulation of RUVBL1 2 0.37 1.3 0.43 100.00
81 INT28760 Negative_regulation of Crlf1 1 0.16 0.52 0 100.00
82 INT169187 Positive_regulation of Gene_expression of Adam10 1 0.60 2.3 0.48 100.00
83 INT176264 Binding of PCNA 21 0.21 9.08 0.51 100.00
84 INT297520 Gene_expression of T(2;4)1Ca 1 0.07 1.26 0.17 100.00
85 INT151029 Positive_regulation of Gene_expression of Lcn2 8 0.68 4.04 2.65 100.00
86 INT274757 Negative_regulation of Positive_regulation of ASPSCR1 1 0.26 1.15 0 100.00
87 INT274759 Negative_regulation of ASPSCR1 1 0.26 1.1 0 100.00
88 INT274760 Negative_regulation of Gene_expression of ASPSCR1 1 0.26 1.1 0 100.00
89 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 100.00
90 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38 100.00
91 INT28802 Binding of F2 15 0.47 8.8 3.47 100.00
92 INT28094 Binding of PTH 29 0.37 13.57 3.09 100.00
93 INT68394 Gene_expression of KISS1 15 0.73 5.33 2.03 100.00
94 INT49957 Positive_regulation of Localization of SGCG 2 0.49 0.92 1.03 100.00
95 INT75971 Regulation of B2m 7 0.45 3.96 0.37 100.00
96 INT159139 Positive_regulation of MALAT1 3 0.41 1.73 0.33 100.00
97 INT349874 Positive_regulation of Gene_expression of Pcyt1a 1 0.04 3.54 0.22 100.00
98 INT122984 Localization of CLU 2 0.78 2.46 0.16 100.00
99 INT122989 Positive_regulation of Localization of CLU 2 0.45 1.81 0.16 100.00
100 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.98
101 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33 99.98
102 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 99.98
103 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2 99.98
104 INT107042 Regulation of Ts1 3 0.44 1.68 0.22 99.98
105 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03 99.98
106 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 99.96
107 INT239217 Gene_expression of Agtrap 47 0.78 48.8 4.44 99.96
108 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 99.96
109 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.96
110 INT267844 Positive_regulation of Gene_expression of Ace 10 0.57 15.35 0.35 99.96
111 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 99.96
112 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 99.96
113 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67 99.96
114 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 99.96
115 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 99.96
116 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 99.96
117 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 99.96
118 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 99.96
119 INT214067 Regulation of Scrib 11 0.20 12.48 0.45 99.96
120 INT88948 Localization of Ace 9 0.69 9.18 1.11 99.96
121 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35 99.96
122 INT4863 Positive_regulation of ap 22 0.37 9.13 6.11 99.96
123 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 99.96
124 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42 99.96
125 INT34761 Negative_regulation of Gene_expression of PCa 6 0.36 4.89 0.35 99.96
126 INT261714 Negative_regulation of Dbm2 1 0.45 4.15 0.04 99.96
127 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 99.96
128 INT114878 Positive_regulation of Gene_expression of Stat3 15 0.49 10.81 2.91 99.96
129 INT139852 Regulation of HCC 14 0.39 14.54 0.97 99.96
130 INT20461 Binding of Esr1 34 0.48 9.58 3.66 99.96
131 INT158452 Negative_regulation of GIT1 3 0.22 1.16 2.13 99.96
132 INT291367 Negative_regulation of Gene_expression of CXCL12 3 0.32 4.15 0.47 99.96
133 INT164205 Binding of Proc 12 0.36 12.31 1.19 99.96
134 INT20633 Positive_regulation of Gene_expression of LDHA 15 0.49 15.94 1.42 99.96
135 INT131844 Gene_expression of MATN3 12 0.78 9.65 0.92 99.96
136 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 99.96
137 INT27455 Positive_regulation of C2 18 0.60 4.3 3.93 99.96
138 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 99.92
139 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42 99.92
140 INT144430 Gene_expression of Erbb2 137 0.77 103.87 8.66 99.92
141 INT232510 Negative_regulation of Gene_expression of CXCR4 18 0.58 20.27 2.54 99.92
142 INT70242 Localization of HCC 18 0.66 23.95 2.35 99.92
143 INT144428 Positive_regulation of Gene_expression of Erbb2 41 0.69 41.4 4.13 99.92
144 INT8670 Negative_regulation of Afp 27 0.58 19.85 2.87 99.92
145 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 99.92
146 INT172556 Negative_regulation of Localization of Proc 3 0.01 5.81 0.19 99.92
147 INT131849 Negative_regulation of RHOC 4 0.54 6.46 0.34 99.92
148 INT97856 Regulation of Slc5a5 3 0.16 3.52 0.24 99.92
149 INT230806 Positive_regulation of Gene_expression of Agt 11 0.55 16.08 0.83 99.92
150 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 99.92
151 INT226637 Negative_regulation of Cxcr4 41 0.48 24.42 1.91 99.92
152 INT213533 Positive_regulation of Gene_expression of Proc 6 0.01 5.55 0.49 99.92
153 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 99.92
154 INT126479 Regulation of Cxcr4 11 0.58 10.75 0.34 99.92
155 INT35558 Binding of Sts 4 0.32 3.76 0.48 99.92
156 INT99443 Regulation of Proc 6 0.23 5.28 0.24 99.92
157 INT294604 Binding of Serpinh1 5 0.16 4.02 0.36 99.92
158 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 99.92
159 INT116950 Negative_regulation of MAPK8 103 0.57 44.48 17.53 99.92
160 INT17268 Localization of PLG 9 0.78 11.71 2.06 99.92
161 INT6603 Gene_expression of ITGA3 10 0.29 7.88 0.46 99.92
162 INT80452 Positive_regulation of Gene_expression of Pthlh 4 0.40 3.77 0.62 99.92
163 INT128061 Negative_regulation of Gene_expression of Serpine1 16 0.43 13.13 1.29 99.92
164 INT6600 Negative_regulation of Gene_expression of ITGA3 1 0.22 2.96 0.13 99.92
165 INT74237 Positive_regulation of Ppt1 3 0.49 2.92 2.32 99.92
166 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 99.92
167 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.90
168 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 99.90
169 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 99.90
170 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.90
171 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 99.90
172 INT113319 Positive_regulation of QRFP 5 0.40 3.86 0.1 99.90
173 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 99.90
174 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 99.90
175 INT203875 Phosphorylation of GSTM1 2 0.81 1.27 0 99.90
176 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22 99.90
177 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 99.88
178 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.88
179 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76 99.88
180 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 99.88
181 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31 99.88
182 INT126534 Negative_regulation of ROCK1 18 0.49 14.32 1.13 99.88
183 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 99.88
184 INT71763 Gene_expression of Mri1 33 0.58 12.56 8.6 99.88
185 INT93274 Gene_expression of QRFP 12 0.58 7 1.46 99.88
186 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 99.88
187 INT301392 Negative_regulation of Gene_expression of Enpp2 1 0.58 3.16 0.07 99.88
188 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 99.88
189 INT2723 Gene_expression of Salpa1 16 0.64 11.78 3.5 99.88
190 INT153667 Localization of CAV1 15 0.76 11.92 0.68 99.88
191 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98 99.88
192 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82 99.88
193 INT301400 Negative_regulation of Negative_regulation of Enpp2 1 0.42 0.9 0.04 99.88
194 INT349882 Gene_expression of Pcyt1a 1 0.05 8.79 0.27 99.88
195 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.86
196 INT126478 Gene_expression of Cxcl12 78 0.77 58.69 8.01 99.86
197 INT348682 Transcription of Plau 1 0.31 0.29 0.04 99.86
198 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 99.86
199 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 99.84
200 INT339094 Gene_expression of Ezh2 1 0.78 67.79 0.05 99.84
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