D:Microsatellite Instability

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Disease Term
Synonyms Error Phenotype Replication, ERROR PHENOTYPES REPLICATION, Instability Microsatellite, Phenotype Replication Error, PHENOTYPES REPLICATION ERROR, Replication Error Phenotype, Replication Error Phenotypes
Documents 70
Hot Single Events 141
Hot Interactions 7

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Microsatellite Instability. They are ordered first by their relevance to Microsatellite Instability and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT277136 Ebp Positive_regulation of Gene_expression of Mlh1 1 0.01 1.45 0 100.00
2 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 100.00
3 INT337679 Binding of MSI1 and Scrib 1 0.00 1.61 0 100.00
4 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0 100.00
5 INT304016 SFRP4 Regulation of Binding of MSI1 1 0.04 1.78 0 100.00
6 INT190051 Binding of Ebp and Mrc1 1 0.04 0.63 0 93.60
7 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47 92.76
8 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0 73.84
9 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24 71.72
10 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0 70.88
11 INT290556 Binding of MLH1 and MSH2 3 0.34 2.74 0 61.44
12 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0 60.52
13 INT304020 AR Regulation of TP53 1 0.24 1.11 0 60.16
14 INT337680 Binding of TP53 and Scrib 1 0.03 1.6 0 53.60
15 INT337639 TP53 Regulation of Gene_expression of MIR34A 1 0.08 1.19 0 49.76
16 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 47.00
17 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 0.29 0.96 0 35.88
18 INT337638 Binding of CSF1 and PSG2 1 0.11 1.52 0 30.16
19 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12 23.28
20 INT190047 Binding of Msh2 and Msh3 1 0.24 0.23 0 20.16
21 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0 19.92
22 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0 19.92
23 INT190046 Binding of Msh3 and Pms2 2 0.25 0.5 0.04 19.36
24 INT190049 Binding of Mlh1 and Msh3 1 0.24 0.22 0 19.36
25 INT190050 Binding of Msh2 and Pms2 2 0.32 0.49 0.04 18.48
26 INT190048 Binding of Mlh1 and Msh2 1 0.31 0.22 0 18.48
27 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0 18.40
28 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0 18.40
29 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0 18.40
30 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0 18.40
31 INT305350 Pten Regulation of Phosphorylation of Akt1 1 0.05 0.95 0 14.64
32 INT348583 MECP2 Regulation of PPARG 1 0.46 0.73 0 11.84
33 INT348591 EZH2 Regulation of Negative_regulation of MECP2 1 0.15 0.73 0 11.84
34 INT348585 EZH2 Regulation of PPARG 1 0.41 0.73 0 11.44
35 INT181896 TNF Regulation of TEK 1 0.03 1.21 0.33 5.00
36 INT181899 TNF Regulation of ANGPT1 1 0.03 1.22 0.33 5.00
37 INT181893 TNF Regulation of ANGPT2 1 0.04 1.22 0.33 5.00
38 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 5.00
39 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28 5.00
40 INT172977 Cdkn1a Negative_regulation of Positive_regulation of Inca1 1 0.00 1.39 0.27 5.00
41 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26 5.00
42 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24 5.00
43 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22 5.00
44 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21 5.00
45 INT334423 Binding of SPINK1 and Cea 1 0.02 2.53 0.17 5.00
46 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15 5.00
47 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15 5.00
48 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15 5.00
49 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13 5.00
50 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 5.00
51 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 5.00
52 INT337676 Binding of TIMP1 and Scrib 1 0.01 1.24 0.13 5.00
53 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11 5.00
54 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09 5.00
55 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 5.00
56 INT197553 Binding of NFE2L2 and LILRA3 1 0.03 0.43 0.06 5.00
57 INT326125 Binding of CXCL3 and IL1RAPL1 1 0.01 1.16 0.05 5.00
58 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05 5.00
59 INT190044 Binding of Msh2 and Msh6 2 0.32 0.77 0.05 5.00
60 INT326128 Binding of CXCL3 and CXCL6 1 0.06 1.18 0.05 5.00
61 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05 5.00
62 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05 5.00
63 INT326127 Binding of CXCL3 and CXCR1 1 0.13 1.16 0.05 5.00
64 INT197546 NFE2L2 Regulation of Gene_expression of ABCC2 1 0.17 0.72 0.04 5.00
65 INT348592 Binding of HDAC1 and PPARG 1 0.23 0 0.03 5.00
66 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03 5.00
67 INT190061 Binding of MLH1 and Mlh1 1 0.01 0.92 0 5.00
68 INT172980 Binding of VEGFA and Kras 1 0.00 0.79 0 5.00
69 INT348594 MECP2 Regulation of Gene_expression of PPARG 1 0.34 0.43 0 5.00
70 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 5.00
71 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0 5.00
72 INT232918 Binding of KRT2 and KRT8 1 0.17 0.59 0 5.00
73 INT337677 Scrib Positive_regulation of Gene_expression of MMP9 1 0.03 1.12 0 5.00
74 INT348584 EZH2 Regulation of Gene_expression of PPARG 1 0.30 0.43 0 5.00
75 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0 5.00
76 INT300616 Binding of MLH1 and PMS2 1 0.36 0.53 0 5.00
77 INT326163 Binding of Racgap1 and RAB12 1 0.00 0.68 0 5.00
78 INT310186 Binding of Gdf2 and Bmpr2 1 0.02 0 0 5.00
79 INT310191 Flt3 Positive_regulation of Gene_expression of Id1 1 0.03 0.81 0 5.00
80 INT326162 Binding of ABHD2 and Scrib 1 0.00 1.07 0 5.00
81 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0 5.00
82 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0 5.00
83 INT348588 MECP2 Positive_regulation of Gene_expression of EZH2 1 0.28 0.42 0 5.00
84 INT268345 Binding of TGFB1 and TGFBR2 1 0.27 0.62 0 5.00
85 INT320712 Binding of NRAS and PIK3CD 1 0.21 1.66 0 5.00
86 INT348593 ZACN Regulation of Positive_regulation of PPARG 1 0.14 0.41 0 5.00
87 INT348596 EZH2 Positive_regulation of Gene_expression of MECP2 1 0.28 0.42 0 5.00
88 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0 5.00
89 INT320713 NRAS Positive_regulation of AKT1 1 0.37 0.84 0 5.00
90 INT268397 Binding of Kras and Regulation of ARAF 1 0.03 1.16 0 5.00
91 INT197576 Loh1 Positive_regulation of NFE2L2 1 0.49 1.1 0 5.00
92 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 5.00
93 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0 5.00
94 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0 5.00
95 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0 5.00
96 INT232912 Binding of KRT4 and KRT13 1 0.07 0.06 0 5.00
97 INT268341 SMAD2 Positive_regulation of SMAD4 1 0.31 0.56 0 5.00
98 INT232910 Binding of KRT12 and KRT76 1 0.39 0.2 0 5.00
99 INT197544 Binding of KEAP1 and KLHL2 1 0.02 0.43 0 5.00
100 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0 5.00
101 INT175400 RASGRP1 Positive_regulation of MAP3K5 1 0.00 1.2 0 5.00
102 INT232911 Binding of KRT18 and PLAT 1 0.05 1.3 0 5.00
103 INT324605 Binding of CEACAM7 and SNCG 1 0.39 4.68 0 5.00
104 INT348587 Binding of MECP2 and PPARG 1 0.32 0.25 0 5.00
105 INT197547 Binding of PTS and KEAP1 1 0.08 1.23 0 5.00
106 INT337678 Scrib Positive_regulation of MMP7 1 0.03 1.11 0 5.00
107 INT268342 Binding of APC and ANKS1B 1 0.01 0.92 0 5.00
108 INT197552 GSTK1 Positive_regulation of NQO1 1 0.09 1.06 0 5.00
109 INT232915 Binding of KRT8 and PLAT 1 0.04 1.3 0 5.00
110 INT232909 Binding of KRT1 and KRT9 1 0.16 0.5 0 5.00
111 INT175399 Binding of TP53 and SACM1L 1 0.00 2.37 0 5.00
112 INT337681 Scrib Positive_regulation of MMP9 1 0.01 1.12 0 5.00
113 INT310187 Acvrl1 Regulation of Gene_expression of Bmpr2 1 0.04 0 0 5.00
114 INT348586 RSPH1 Positive_regulation of Gene_expression of PPARG 1 0.02 0.23 0 5.00
115 INT320715 NRAS Positive_regulation of PIK3CD 1 0.27 1.66 0 5.00
116 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0 5.00
117 INT268398 Binding of LRP1 and Wnt2 1 0.01 0.36 0 5.00
118 INT268395 Binding of APC and Kras 1 0.04 1.21 0 5.00
119 INT326165 Binding of ABHD12 and Scrib 1 0.00 1.01 0 5.00
120 INT190062 Binding of MLH1 and Msh2 1 0.01 0.91 0 5.00
121 INT310189 Binding of Acvrl1 and Gdf2 1 0.01 0 0 5.00
122 INT197545 KEAP1 Regulation of NFE2L2 3 0.49 0.8 0 5.00
123 INT268340 TGFBR2 Positive_regulation of Phosphorylation of TGFB1 1 0.25 0.68 0 5.00
124 INT310190 Binding of Adcyap1r1 and Smad6 1 0.00 0 0 5.00
125 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0 5.00
126 INT300617 Binding of MSH6 and MLH1 1 0.28 0.53 0 5.00
127 INT232913 Binding of KRT3 and NBPF14 1 0.01 0.21 0 5.00
128 INT326164 Binding of S100A2 and Scrib 1 0.01 1.16 0 5.00
129 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0 5.00
130 INT348595 Binding of PPARG and ZACN 1 0.07 0.38 0 5.00
131 INT334422 SPINK1 Regulation of Gene_expression of Cea 1 0.02 1 0 5.00
132 INT232908 Binding of KRT19 and PLAT 1 0.05 1.31 0 5.00
133 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0 5.00
134 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0 5.00
135 INT268396 Binding of BRAF and Ebp 1 0.01 1.72 0 5.00
136 INT268344 SMAD3 Positive_regulation of SMAD4 1 0.17 0.56 0 5.00
137 INT186889 Binding of AHR and PC 1 0.05 1.06 0 5.00
138 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Microsatellite Instability. They are ordered first by their pain relevance and then by number of times they were reported in Microsatellite Instability. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT146546 Gene_expression of MSI1 22 0.48 22.91 1.15 100.00
2 INT304052 Binding of MSI1 8 0.05 12.19 0 100.00
3 INT61907 Negative_regulation of Ebp 9 0.37 4.77 2.49 100.00
4 INT156805 Gene_expression of Ebp 6 0.40 6.09 1.07 100.00
5 INT304058 Positive_regulation of MSI1 1 0.07 2.74 0 100.00
6 INT86906 Negative_regulation of RMI1 2 0.03 1.75 1.17 100.00
7 INT86911 Regulation of RMI1 2 0.01 1.01 0.52 100.00
8 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 100.00
9 INT147919 Regulation of Ebp 1 0.08 0.94 0.48 100.00
10 INT147918 Positive_regulation of Negative_regulation of Ebp 1 0.14 0.88 0.42 100.00
11 INT282953 Regulation of MSI1 2 0.03 1.63 0.03 100.00
12 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 100.00
13 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32 100.00
14 INT226027 Positive_regulation of Gene_expression of Ebp 1 0.13 2.46 0.06 100.00
15 INT288233 Localization of TYMS 2 0.22 2.17 0.04 100.00
16 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 99.98
17 INT337653 Gene_expression of BAAT 1 0.06 1.51 0 99.98
18 INT107983 Gene_expression of MSH6 6 0.51 5.57 0.27 99.96
19 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 99.96
20 INT181920 Gene_expression of MSH3 2 0.50 2.54 0.18 99.96
21 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 99.96
22 INT190053 Gene_expression of CASP5 3 0.45 2.46 0 99.96
23 INT65855 Localization of TP53 18 0.76 17.08 1.89 99.96
24 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 99.92
25 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 99.92
26 INT86370 Regulation of CDH1 10 0.54 13.89 0.7 99.86
27 INT304045 Transcription of PTEN 2 0.51 4.12 1.4 99.84
28 INT107991 Positive_regulation of Gene_expression of MSH6 3 0.38 1.35 0 99.84
29 INT190039 Gene_expression of Mlh1 3 0.68 6.14 0 99.82
30 INT132521 Gene_expression of BRAF 14 0.65 13.59 0.73 99.80
31 INT320723 Negative_regulation of Gene_expression of BRAF 2 0.38 1 0.03 99.80
32 INT348616 Negative_regulation of Gene_expression of KRAS 1 0.31 0.34 0.03 99.80
33 INT211715 Negative_regulation of Gene_expression of MSH6 1 0.06 1.09 0 99.78
34 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7 99.76
35 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.76
36 INT86907 Negative_regulation of MSH6 8 0.33 6.76 0.93 99.76
37 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12 99.76
38 INT86910 Negative_regulation of MRC1 6 0.20 6.52 0.8 99.60
39 INT81644 Regulation of Ctnnb1 5 0.41 3.38 0.37 99.56
40 INT181744 Negative_regulation of Gene_expression of MLH1 3 0.05 7.67 0.12 99.48
41 INT350588 Negative_regulation of Mlh1 1 0.38 3.05 0 99.48
42 INT190023 Negative_regulation of Mrc1 15 0.25 12.36 0.16 99.48
43 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6 99.46
44 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 99.44
45 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 99.44
46 INT98203 Negative_regulation of KRAS 5 0.42 2.38 0.34 99.40
47 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 99.32
48 INT216395 Negative_regulation of Gene_expression of KRT7 4 0.41 3.57 0.16 99.32
49 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46 99.26
50 INT181745 Positive_regulation of MSH2 4 0.48 5.73 0.11 99.24
51 INT236621 Regulation of KRAS 7 0.53 6.16 0 99.08
52 INT176154 Gene_expression of PIK3CA 6 0.55 10.43 0.03 99.04
53 INT258556 Negative_regulation of BRAF 4 0.42 2.48 0.03 99.04
54 INT92139 Binding of MLH1 12 0.42 15.62 1 98.98
55 INT146545 Negative_regulation of Gene_expression of MSH2 17 0.56 18.87 0.51 98.96
56 INT305347 Negative_regulation of Gene_expression of Msh6 1 0.25 2.22 0 98.96
57 INT198037 Regulation of PIK3CA 2 0.28 2.63 0 98.84
58 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 98.76
59 INT305349 Gene_expression of Msh6 1 0.46 2.21 0 98.72
60 INT86368 Gene_expression of TEP1 31 0.50 16.36 1.63 98.68
61 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 98.64
62 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57 98.64
63 INT190022 Positive_regulation of Mlh1 2 0.38 3.16 0.03 98.60
64 INT179885 Regulation of PTEN 8 0.26 11.88 2.18 98.52
65 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 98.48
66 INT159293 Negative_regulation of PMS1 2 0.03 1.94 0 98.34
67 INT291365 Positive_regulation of Gene_expression of PIK3CA 2 0.41 5.76 0 98.28
68 INT57062 Regulation of APC 24 0.58 14.3 0.7 98.28
69 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22 98.28
70 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19 98.16
71 INT192676 Binding of PTEN 14 0.46 10.58 3.06 97.88
72 INT127888 Negative_regulation of HMMR 3 0.11 3.89 0.55 97.84
73 INT145302 Positive_regulation of Sox9 2 0.48 1.42 0.03 97.52
74 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 97.12
75 INT68094 Negative_regulation of SERPINB3 12 0.43 10.55 1.49 97.00
76 INT182627 Regulation of MSH2 1 0.26 2.27 0.18 96.96
77 INT60585 Regulation of TP53 59 0.59 54.55 5.21 96.80
78 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 96.72
79 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 96.72
80 INT50671 Regulation of Gene_expression of CPOX 45 0.54 30.99 13.83 96.68
81 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 96.44
82 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 96.44
83 INT107986 Gene_expression of PMS1 2 0.19 1.58 0.39 96.44
84 INT64928 Regulation of LEPRE1 2 0.24 1.26 0.54 95.96
85 INT281619 Regulation of Cdk2ap1 1 0.01 1 0 95.96
86 INT98708 Binding of KRAS 13 0.47 7.47 0.39 95.92
87 INT92142 Binding of MSH2 5 0.46 5.64 0.75 95.80
88 INT211581 Binding of Pms2 2 0.32 2.49 0.04 95.80
89 INT190035 Binding of Msh6 2 0.28 2.72 0 95.80
90 INT190038 Binding of Mlh1 2 0.28 3.11 0 95.80
91 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 95.56
92 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 95.56
93 INT172329 Binding of MRC1 8 0.36 3.88 0.03 95.24
94 INT207233 Transcription of KRAS 3 0.48 1.56 0.03 95.16
95 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 94.96
96 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71 94.96
97 INT128916 Regulation of CES1 5 0.40 2.95 0.29 94.92
98 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 94.56
99 INT12082 Localization of IL6 365 0.81 241.78 105.78 94.52
100 INT86437 Binding of IL6 154 0.48 121.22 29.3 94.52
101 INT175422 Positive_regulation of SACM1L 1 0.00 2.11 0 94.48
102 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 93.84
103 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 93.60
104 INT112993 Binding of Mrc1 7 0.21 6.55 0.12 92.48
105 INT310168 Phosphorylation of Tgfbr2 1 0.41 1.5 0 92.12
106 INT304074 Binding of MSH5 1 0.14 1.11 0 92.08
107 INT350584 Negative_regulation of Gene_expression of Mlh1 1 0.51 2.21 0 92.04
108 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 92.00
109 INT304071 Binding of MSH6 1 0.28 1.11 0 91.68
110 INT319141 Regulation of MTUS1 1 0.00 1.56 0 91.60
111 INT23654 Binding of SPINK1 27 0.48 30.85 11.53 91.56
112 INT232950 Negative_regulation of Gene_expression of KRT8 1 0.25 0.79 0 91.32
113 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8 91.20
114 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 91.00
115 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 90.80
116 INT281624 Gene_expression of Tag 2 0.58 8 2.4 90.48
117 INT226028 Gene_expression of Trove2 4 0.65 9.97 0.54 89.28
118 INT182605 Gene_expression of Golga4 1 0.01 1.41 0.03 89.08
119 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 88.04
120 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39 88.04
121 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 87.92
122 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 87.68
123 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 87.68
124 INT202848 Gene_expression of Nf2 5 0.59 4.93 0.63 87.68
125 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 87.36
126 INT57644 Regulation of SPINK1 7 0.47 15.19 3.64 87.08
127 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 86.96
128 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15 86.96
129 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 86.96
130 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 86.56
131 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37 86.56
132 INT3818 Regulation of Apc 13 0.39 12.52 1.68 86.28
133 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54 86.24
134 INT234676 Gene_expression of SNCG 4 0.78 63.59 0.08 84.64
135 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 84.60
136 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 84.60
137 INT231978 Binding of SERPINB3 9 0.36 8.33 0 82.56
138 INT78281 Gene_expression of Krt7 28 0.70 26.77 0.97 82.12
139 INT8224 Gene_expression of CHGA 73 0.75 53.63 12.31 82.12
140 INT101816 Localization of NFE2L2 17 0.77 6.91 1.69 81.72
141 INT190031 Binding of Scrib 19 0.36 21.9 1.01 81.48
142 INT68288 Positive_regulation of SERPINB3 14 0.51 16.87 0.41 78.88
143 INT350742 Positive_regulation of Positive_regulation of SERPINB3 1 0.04 2.54 0 78.88
144 INT200666 Transcription of AKT1 8 0.66 4.23 0.2 78.48
145 INT286102 Positive_regulation of Fap 5 0.30 8.58 0.04 78.48
146 INT114246 Positive_regulation of Negative_regulation of EGFR 13 0.49 8.67 0.7 78.08
147 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 78.08
148 INT100914 Binding of PTS 5 0.36 3.81 0.21 78.08
149 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 77.68
150 INT350591 Positive_regulation of Gart 1 0.11 0.96 0.1 77.60
151 INT68285 Gene_expression of SERPINB3 24 0.75 25.4 0.45 76.96
152 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12 76.64
153 INT79690 Negative_regulation of Gene_expression of PPARG 10 0.59 10.48 1.55 76.56
154 INT18156 Gene_expression of Fap 18 0.73 27.02 1.46 76.00
155 INT101818 Gene_expression of NFE2L2 48 0.78 23.8 0.66 75.92
156 INT190014 Regulation of Pten 8 0.62 6.03 1.2 75.84
157 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 75.44
158 INT91941 Gene_expression of REEP5 3 0.20 1.76 0.32 75.00
159 INT105354 Gene_expression of D2Mit123 1 0.00 0.31 0.07 75.00
160 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 74.00
161 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 74.00
162 INT337670 Positive_regulation of DEFA3 7 0.42 10.51 0 73.12
163 INT337660 Positive_regulation of Positive_regulation of DEFA3 4 0.42 5.4 0 73.12
164 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 72.92
165 INT105948 Gene_expression of AURKA 5 0.65 4.26 0.03 72.88
166 INT105949 Positive_regulation of Gene_expression of AURKA 3 0.49 1.91 0.03 72.88
167 INT38672 Binding of KRT20 69 0.39 48.01 6.31 72.64
168 INT190020 Gene_expression of Msh2 2 0.69 0.69 0 72.40
169 INT198405 Binding of CDX2 1 0.32 1.01 0 72.28
170 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 71.56
171 INT181915 Negative_regulation of Binding of NOS2 1 0.16 0.95 0.25 71.56
172 INT116836 Binding of FAP 6 0.37 6.76 1.47 71.36
173 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 71.00
174 INT268383 Gene_expression of MUTYH 1 0.46 2.56 0 70.96
175 INT268374 Gene_expression of FAP 2 0.37 6.6 0 70.96
176 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 70.88
177 INT184732 Localization of SNCG 5 0.70 3.04 0 70.84
178 INT101832 Positive_regulation of Gene_expression of NFE2L2 16 0.67 7.41 0.12 70.68
179 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 70.40
180 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 70.40
181 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 70.40
182 INT121052 Binding of NOS2 3 0.35 3.12 1.12 69.36
183 INT211714 Regulation of Gene_expression of VIM 4 0.43 3.77 0.52 68.88
184 INT78248 Negative_regulation of Cdkn2a 17 0.59 15.15 2.8 68.56
185 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 68.36
186 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 68.24
187 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 68.04
188 INT182625 Positive_regulation of Localization of MSH2 1 0.45 2.47 0 67.68
189 INT182624 Positive_regulation of Positive_regulation of MSH2 1 0.45 1.24 0 67.68
190 INT61418 Positive_regulation of ITGAL 24 0.14 12.86 2.3 67.32
191 INT182623 Localization of MSH2 3 0.77 5.49 0.12 66.84
192 INT33009 Gene_expression of Cdk2ap1 6 0.31 6.69 0.33 66.56
193 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98 66.40
194 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 66.24
195 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 65.60
196 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13 65.36
197 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4 65.36
198 INT172479 Positive_regulation of NFE2L2 74 0.70 35.22 0.79 65.12
199 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53 64.56
200 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 64.56
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