D:Microvascular Angina

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Disease Term
Synonyms Angina Microvascular, ANGINA PECTORIS WITH NORMAL CORONARY ARTERIOGRAM, Angina Syndrome X, ANGINA SYNDROME XS, ANGINA X SYNDROME, ANGINA X SYNDROMES, CARDIAC SYNDROME X, Syndrome Angina X, Syndrome X Angina, Syndrome X Cardiac, Syndrome Xs Angina
Documents 145
Hot Single Events 26
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Microvascular Angina. They are ordered first by their relevance to Microvascular Angina and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT58648 Binding of HSD11B1 and INS 1 0.04 1.65 0.07 73.36
2 INT58649 Binding of INS and Serpine1 1 0.01 1.64 0.07 71.84
3 INT131787 Binding of Myo5a and Pon1 1 0.02 0.06 0 50.00
4 INT80661 INS Positive_regulation of GYS1 1 0.13 0.29 0 49.92
5 INT80659 Positive_regulation of INS Positive_regulation of APC 1 0.32 0.65 0 42.24
6 INT80660 INS Positive_regulation of APC 1 0.32 0.65 0 41.88

Single Events

The table below shows the top 200 pain related interactions that have been reported for Microvascular Angina. They are ordered first by their pain relevance and then by number of times they were reported in Microvascular Angina. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.92
2 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05 99.84
3 INT35263 Gene_expression of Apol7b 5 0.55 4.28 0.64 99.84
4 INT5048 Binding of Edn1 55 0.47 18.86 19.16 99.76
5 INT53374 Binding of Edn1 17 0.43 11.66 2.98 99.76
6 INT27587 Positive_regulation of STAR 7 0.46 6.37 0.99 99.40
7 INT14572 Binding of INS 205 0.48 175.43 13.38 99.12
8 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 98.60
9 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 98.34
10 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 98.32
11 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 98.28
12 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8 98.00
13 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 97.76
14 INT2774 Binding of Crp 241 0.48 195.89 44.39 97.60
15 INT120895 Binding of CCL2 22 0.37 15.86 6.55 97.60
16 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 97.16
17 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 97.16
18 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 95.76
19 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 95.76
20 INT9650 Gene_expression of LPA 141 0.75 104.57 29 93.68
21 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67 92.04
22 INT15921 Positive_regulation of Serpine1 85 0.68 81.24 13.4 92.04
23 INT57599 Positive_regulation of Btg1 2 0.03 2 0.09 92.04
24 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55 84.72
25 INT137455 Protein_catabolism of ADIPOQ 1 0.66 0.25 0.17 82.56
26 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 82.16
27 INT70173 Gene_expression of SLC6A2 6 0.65 5.26 1.76 78.80
28 INT70172 Localization of SLC6A2 1 0.68 1.11 0.28 78.80
29 INT161716 Localization of Nkx2-5 2 0.74 2.17 1.02 75.00
30 INT10974 Localization of Hpn 2 0.12 0.64 0.22 75.00
31 INT125192 Negative_regulation of Localization of Hpn 1 0.03 0.35 0.16 75.00
32 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11 74.32
33 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17 74.32
34 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 72.16
35 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69 72.16
36 INT80666 Negative_regulation of Gene_expression of GYS1 1 0.13 0.6 0.07 71.84
37 INT80670 Gene_expression of GYS1 1 0.24 0.6 0.07 71.84
38 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 71.72
39 INT323415 Regulation of NKX2-5 1 0.39 0.71 0.1 70.88
40 INT80667 Gene_expression of PFKM 4 0.57 2.13 0.07 70.00
41 INT80669 Negative_regulation of Gene_expression of PFKM 1 0.31 0.59 0.07 70.00
42 INT80665 Negative_regulation of Gene_expression of HK2 4 0.39 2.41 0.84 67.84
43 INT80671 Gene_expression of HK2 6 0.70 3.23 0.84 67.84
44 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81 60.72
45 INT137453 Gene_expression of APOA4 2 0.17 1.21 0.26 54.00
46 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 53.12
47 INT15407 Positive_regulation of Positive_regulation of Edn1 5 0.62 3.69 1.49 50.12
48 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 50.00
49 INT114993 Binding of Myo5a 15 0.30 11.46 5.48 50.00
50 INT124220 Binding of Pon1 9 0.47 7.84 0.99 50.00
51 INT125193 Positive_regulation of Hpn 1 0.03 0 0 50.00
52 INT4259 Positive_regulation of Npr1 262 0.70 49.37 123.11 25.00
53 INT25200 Positive_regulation of GPER 13 0.05 1.75 3.67 25.00
54 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 25.00
55 INT9140 Negative_regulation of PFKM 14 0.59 12.67 3.61 25.00
56 INT80668 Regulation of PFKM 2 0.24 0.95 0.42 25.00
57 INT80664 Phosphorylation of G6PD 3 0.08 0.58 0.3 25.00
58 INT9138 Positive_regulation of Negative_regulation of PFKM 2 0.47 1.32 0.14 25.00
59 INT80672 Positive_regulation of PFKM 1 0.34 0.5 0 25.00
60 INT80673 Positive_regulation of Regulation of PFKM 1 0.34 0.5 0 25.00
61 INT305390 Negative_regulation of NKX2-5 2 0.37 2.24 0.49 23.68
62 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 5.00
63 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
64 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 5.00
65 INT98498 Binding of Trpv1 75 0.48 33.67 44.4 5.00
66 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 5.00
67 INT162037 Negative_regulation of Regulation of TRPV1 2 0.43 2.47 1.31 5.00
68 INT34141 Positive_regulation of IMPA1 8 0.50 2.38 1.12 5.00
69 INT92988 Protein_catabolism of Eln 6 0.47 5.48 1.03 5.00
70 INT109062 Gene_expression of NKX2-5 7 0.75 3.31 0.82 5.00
71 INT34143 Regulation of IMPA1 14 0.44 4.83 0.58 5.00
72 INT323416 Localization of NKX2-5 1 0.65 1.75 0.1 5.00
73 INT225036 Positive_regulation of Regulation of IMPA1 1 0.02 0.16 0 5.00
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