D:Middle Ear Cholesteatoma

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pChart

Disease Term
Synonyms Aural Cholesteatoma, Aural Cholesteatomas, CHOLESTEATOMA AURAL, Cholesteatomas Aural, Cholesteatomas Middle Ear, Middle Ear Cholesteatomas
Documents 12
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Middle Ear Cholesteatoma. They are ordered first by their relevance to Middle Ear Cholesteatoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT307225 CYLD Regulation of TNFRSF11A 1 0.14 0.81 0 54.80
2 INT307223 CYLD Positive_regulation of Localization of BCL3 1 0.12 0.51 0.06 5.00
3 INT307226 CYLD Negative_regulation of Localization of BCL3 1 0.10 0.45 0.06 5.00
4 INT307222 CYLD Regulation of Negative_regulation of BCL3 1 0.10 0.3 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Middle Ear Cholesteatoma. They are ordered first by their pain relevance and then by number of times they were reported in Middle Ear Cholesteatoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181177 Gene_expression of CYLD 5 0.69 24.96 0.89 98.00
2 INT185437 Negative_regulation of Gene_expression of CYLD 3 0.52 2.41 0.05 65.20
3 INT307230 Regulation of Localization of CYLD 1 0.40 0.11 0 14.96
4 INT307240 Localization of CYLD 3 0.72 3.09 0.1 14.48
5 INT222845 Gene_expression of Chuk 27 0.52 25.15 2.67 5.36
6 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
7 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
8 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
9 INT195531 Gene_expression of Rel 9 0.75 5.02 2.72 5.00
10 INT53443 Gene_expression of IKBKG 15 0.65 7.5 2.71 5.00
11 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08 5.00
12 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
13 INT214073 Binding of TSC1 9 0.37 22 1.34 5.00
14 INT217438 Binding of Chuk 24 0.25 7.29 1.29 5.00
15 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 5.00
16 INT181179 Binding of CYLD 4 0.43 7.06 0.39 5.00
17 INT185432 Negative_regulation of CYLD 4 0.52 3.19 0.35 5.00
18 INT185452 Regulation of CYLD 6 0.40 6.09 0.21 5.00
19 INT217832 Negative_regulation of Gene_expression of TSC1 5 0.04 5.45 0.21 5.00
20 INT183242 Negative_regulation of Gene_expression of PTEN 6 0.55 3.81 0.16 5.00
21 INT252702 Binding of TRAF2 3 0.23 2.21 0.16 5.00
22 INT307231 Positive_regulation of Gene_expression of CYLD 1 0.45 2.37 0.14 5.00
23 INT307233 Localization of BCL3 1 0.19 0.84 0.11 5.00
24 INT307227 Positive_regulation of Gene_expression of Rel 2 0.67 1.18 0.09 5.00
25 INT175210 Binding of TRAF6 2 0.17 0.73 0.08 5.00
26 INT307229 Phosphorylation of CYLD 1 0.73 1.02 0.05 5.00
27 INT307236 Negative_regulation of Localization of BCL3 1 0.10 0.33 0.05 5.00
28 INT307232 Negative_regulation of BCL3 1 0.09 0.24 0 5.00
29 INT307235 Positive_regulation of Binding of CYLD 1 0.45 1.1 0 5.00
30 INT307244 Regulation of Gene_expression of CYLD 1 0.24 1.84 0 5.00
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