D:Miosis

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Disease Term
Synonyms Constricted Pupil, Constricted Pupils, Mioses, Mioses Persistent, Mioses Pupillary, MIOSIS PERSISTENT, MIOSIS PUPILLARY, Persistent Mioses, PERSISTENT MIOSIS, PUPIL CONSTRICTED, Pupil Small
Documents 354
Hot Single Events 50
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Miosis. They are ordered first by their relevance to Miosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 5.00
2 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 5.00
3 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 5.00
4 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 5.00
5 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19 5.00
6 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 5.00
7 INT311764 Opn4 Regulation of Mrgprc1-ps 1 0.43 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Miosis. They are ordered first by their pain relevance and then by number of times they were reported in Miosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT69314 Binding of CYP3A 16 0.48 1.78 2.19 100.00
2 INT61652 Gene_expression of Mir343 1 0.10 0.87 0.26 99.98
3 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.96
4 INT60779 Negative_regulation of CYP3A 63 0.59 8.38 21.27 99.48
5 INT13897 Localization of Sst 65 0.81 14.91 32.24 99.44
6 INT5061 Negative_regulation of Mme 306 0.59 51.97 136.9 99.32
7 INT1837 Gene_expression of Olfr1284 1 0.67 0.4 0.04 98.60
8 INT268009 Gene_expression of Gpsm2 12 0.54 0.23 1.34 98.48
9 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66 97.20
10 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 97.20
11 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 97.00
12 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 96.76
13 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 95.44
14 INT182676 Transcription of C4B 1 0.31 4.82 3.66 95.04
15 INT1352 Localization of Acot1 728 0.80 73.01 296.01 94.68
16 INT3766 Positive_regulation of Localization of Acot1 192 0.69 21.8 85.35 94.68
17 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 94.56
18 INT17938 Binding of Cpe 28 0.48 11.17 13.62 94.24
19 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 94.08
20 INT17885 Negative_regulation of YWHAZ 6 0.56 2.74 1.58 91.64
21 INT282809 Negative_regulation of Positive_regulation of YWHAZ 1 0.03 1.07 0.52 91.64
22 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 91.52
23 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 91.52
24 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 91.52
25 INT18345 Positive_regulation of Positive_regulation of Gnrhr 16 0.42 4.99 4.91 91.52
26 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 91.28
27 INT242745 Regulation of FANCE 2 0.28 1.98 0.66 91.20
28 INT124136 Positive_regulation of YWHAZ 7 0.67 1.85 4.51 91.12
29 INT37254 Negative_regulation of MTM1 2 0.36 0.76 1.09 90.60
30 INT61651 Positive_regulation of Mir343 1 0.06 0.54 0.07 89.24
31 INT1316 Positive_regulation of Acot1 129 0.60 18.86 56.13 88.96
32 INT12334 Positive_regulation of CYP3A 34 0.70 6.77 7.85 88.72
33 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 88.64
34 INT3948 Regulation of Cck 291 0.62 58.07 255.88 88.32
35 INT25463 Negative_regulation of Gene_expression of MRXS5 7 0.38 4.75 2.12 88.24
36 INT32509 Positive_regulation of Npc1 6 0.50 2.24 0.33 88.16
37 INT10565 Gene_expression of MRXS5 94 0.53 37.35 19.08 87.64
38 INT169776 Gene_expression of Opn4 52 0.77 8.75 1.38 86.80
39 INT51137 Negative_regulation of GSTM1 39 0.43 14.74 6.5 86.56
40 INT50070 Negative_regulation of NFKBIL1 14 0.48 3.76 5.92 86.56
41 INT12333 Regulation of CYP3A 18 0.62 2.25 6.74 86.28
42 INT14506 Regulation of Sst 46 0.62 15.02 22.66 85.84
43 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 85.36
44 INT57088 Negative_regulation of Slc14a2 9 0.19 2.27 2.39 85.04
45 INT32581 Positive_regulation of C4B 9 0.45 11.17 9.05 84.60
46 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 84.28
47 INT271161 Negative_regulation of Negative_regulation of SYNE1 1 0.00 0.24 0.47 83.76
48 INT181642 Negative_regulation of Narf 2 0.01 28.07 4.01 83.20
49 INT271160 Negative_regulation of SYNE1 1 0.00 0.67 0.81 82.36
50 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 81.20
51 INT22557 Gene_expression of BMP1 3 0.59 20.18 4.73 79.16
52 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 78.56
53 INT215809 Gene_expression of Kcnma1 11 0.58 0.53 0.66 78.24
54 INT158651 Gene_expression of Plxna2 9 0.66 1.98 0.98 77.92
55 INT63057 Regulation of CYP3A4 31 0.61 5.75 6.92 76.48
56 INT33781 Binding of Pebp1 11 0.44 1.76 6.61 76.08
57 INT32579 Binding of C4B 14 0.36 14.99 7.79 75.44
58 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3 75.20
59 INT57923 Gene_expression of CYP3A 12 0.71 2.62 2 75.04
60 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83 74.64
61 INT2541 Binding of Calca 200 0.48 67.14 134.62 74.12
62 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 72.72
63 INT26555 Regulation of Positive_regulation of Oprd1 6 0.59 2.47 5.76 72.72
64 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 71.92
65 INT94347 Gene_expression of DYSF 4 0.75 3.25 0.41 70.04
66 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 68.88
67 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 68.00
68 INT84826 Negative_regulation of ACD 6 0.50 4.02 0.55 64.64
69 INT52512 Positive_regulation of SLC43A3 21 0.41 5.39 5.27 64.00
70 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88 61.28
71 INT178548 Localization of AAAS 1 0.70 1.52 0.07 60.56
72 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 60.16
73 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 59.92
74 INT160553 Regulation of C4B 3 0.14 1.54 1.16 59.44
75 INT181636 Positive_regulation of Gene_expression of BMP1 2 0.44 4.46 0.68 56.24
76 INT172551 Negative_regulation of INCENP 38 0.07 20.83 3.14 56.08
77 INT39369 Binding of NARFL 14 0.29 16.7 0.93 54.72
78 INT274339 Negative_regulation of Binding of NARFL 1 0.06 0.58 0.17 54.72
79 INT2649 Regulation of Calca 433 0.62 146.05 330.95 53.44
80 INT202690 Positive_regulation of Krt36 2 0.49 0.05 0.19 53.36
81 INT281933 Localization of YWHAZ 2 0.09 1.08 0.27 50.48
82 INT307632 Regulation of Binding of BMP1 1 0.34 1.53 0.12 50.16
83 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 50.00
84 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 50.00
85 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 50.00
86 INT5916 Positive_regulation of HTR1A 51 0.67 18.27 21.38 50.00
87 INT100094 Regulation of Positive_regulation of CYP3A4 3 0.45 0.31 0.1 50.00
88 INT307631 Positive_regulation of Binding of BMP1 1 0.38 2.99 0.24 49.84
89 INT307634 Binding of BMP1 1 0.36 3.12 3.26 49.44
90 INT51098 Positive_regulation of Negative_regulation of Nisch 1 0.01 0.5 0.1 47.80
91 INT51099 Negative_regulation of Nisch 6 0.43 0.97 2.93 46.00
92 INT1353 Negative_regulation of Localization of Acot1 153 0.53 15.05 75.17 45.04
93 INT307630 Negative_regulation of Localization of BMP1 1 0.32 1.41 0.21 42.48
94 INT307635 Positive_regulation of Localization of BMP1 1 0.38 1.35 0.36 41.60
95 INT282596 Localization of BMP1 2 0.61 4.04 1.97 41.36
96 INT35744 Binding of MAOB 13 0.46 7.52 4.26 39.40
97 INT61650 Protein_catabolism of Tac1 3 0.52 0.88 1.98 35.92
98 INT27536 Gene_expression of Caf 4 0.52 0.41 1.13 32.64
99 INT58083 Positive_regulation of DYT10 10 0.67 3.66 7.12 30.72
100 INT64045 Localization of DYT10 4 0.78 0.7 3.4 30.72
101 INT107771 Localization of HSPG2 10 0.78 8.47 4.3 29.80
102 INT43259 Negative_regulation of FAIM3 7 0.43 2.7 3.41 25.68
103 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 25.00
104 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 25.00
105 INT18190 Regulation of DRD2 11 0.60 9.01 7.63 25.00
106 INT173090 Regulation of INCENP 24 0.09 9.45 2.16 22.04
107 INT171747 Gene_expression of ACD 4 0.57 4.44 0.68 16.44
108 INT294915 Positive_regulation of Gene_expression of ACD 1 0.43 1.08 0.2 16.44
109 INT159148 Localization of ACD 3 0.65 1.28 0.14 15.52
110 INT294914 Positive_regulation of Localization of ACD 1 0.43 0.53 0.1 15.52
111 INT158652 Positive_regulation of Gene_expression of Plxna2 3 0.59 0.17 0.41 12.44
112 INT283911 Positive_regulation of Negative_regulation of Plxna2 1 0.33 0 0.33 11.80
113 INT278919 Binding of Opn1mw 2 0.35 0 0.18 11.52
114 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 10.96
115 INT132551 Negative_regulation of Plxna2 3 0.36 0.86 1.11 9.96
116 INT330977 Transcription of Aes 1 0.38 0.53 0.38 8.08
117 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
118 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
119 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 5.00
120 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
121 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 5.00
122 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
123 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 5.00
124 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 5.00
125 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
126 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 5.00
127 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
128 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
129 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
130 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 5.00
131 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 5.00
132 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
133 INT6176 Positive_regulation of Htr1a 117 0.67 28.23 66.17 5.00
134 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
135 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
136 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
137 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
138 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 5.00
139 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
140 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 5.00
141 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 5.00
142 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
143 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
144 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 5.00
145 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
146 INT51685 Gene_expression of LTB4R 87 0.58 68.69 31.72 5.00
147 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 5.00
148 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
149 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 5.00
150 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
151 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 5.00
152 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
153 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61 5.00
154 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
155 INT81194 Binding of CPOX 40 0.29 23.7 18.95 5.00
156 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
157 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
158 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 5.00
159 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69 5.00
160 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35 5.00
161 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
162 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 5.00
163 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
164 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
165 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
166 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 5.00
167 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 5.00
168 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
169 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 5.00
170 INT20071 Positive_regulation of HTR2A 33 0.67 10.89 14 5.00
171 INT7057 Binding of FAIM3 19 0.48 4.02 13.78 5.00
172 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 5.00
173 INT15246 Regulation of FOS 32 0.60 15.34 12.94 5.00
174 INT174838 Localization of INCENP 80 0.64 19.05 12.89 5.00
175 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66 5.00
176 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 5.00
177 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
178 INT1252 Binding of Ache 46 0.48 9.94 10.25 5.00
179 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21 5.00
180 INT92777 Positive_regulation of Gene_expression of ABAT 13 0.44 7.49 9.27 5.00
181 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18 5.00
182 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08 5.00
183 INT860 Regulation of ALB 48 0.60 25.11 8.95 5.00
184 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 5.00
185 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13 5.00
186 INT7813 Regulation of SRI 25 0.61 6.18 8.13 5.00
187 INT32580 Gene_expression of C4B 24 0.75 17.95 7.75 5.00
188 INT4022 Negative_regulation of PLA2G1B 30 0.59 10.41 7.58 5.00
189 INT182750 Gene_expression of Hmgcr 61 0.58 17.23 7.4 5.00
190 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36 5.00
191 INT86867 Regulation of CREB1 15 0.46 4.95 7.28 5.00
192 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13 5.00
193 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
194 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89 5.00
195 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7 5.00
196 INT52180 Binding of Aes 38 0.42 23.16 6.7 5.00
197 INT934 Regulation of Gtf3a 25 0.35 11.35 6.34 5.00
198 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14 5.00
199 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 5.00
200 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84 5.00
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