D:Mitochondrial Encephalomyopathies

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pChart

Disease Term
Synonyms Encephalomyopathies Mitochondrial, Encephalomyopathy Mitochondrial, MITOCHONDRIAL ENCEPHALOMYOPATHY
Documents 74
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mitochondrial Encephalomyopathies. They are ordered first by their relevance to Mitochondrial Encephalomyopathies and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT258614 Positive_regulation of Binding of Foxn1 and Tph2 1 0.46 0.06 0 5.00
2 INT258615 Binding of Foxn1 and Tph2 1 0.44 0.06 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mitochondrial Encephalomyopathies. They are ordered first by their pain relevance and then by number of times they were reported in Mitochondrial Encephalomyopathies. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT138555 Negative_regulation of Tymp 3 0.39 3.31 0.74 99.08
2 INT36893 Negative_regulation of Coq10a 36 0.55 22.24 5.47 98.98
3 INT17470 Negative_regulation of NDUFC1 3 0.05 3.43 0.75 95.96
4 INT228549 Negative_regulation of Gene_expression of Coq10a 13 0.36 7.36 0.47 94.60
5 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 94.12
6 INT70916 Binding of Thim 13 0.02 8.35 1.72 91.68
7 INT248419 Negative_regulation of Tph2 11 0.59 6.32 2.59 90.48
8 INT85378 Binding of Pdss1 6 0.28 3.81 1.35 89.52
9 INT288644 Binding of Pdss2 2 0.25 1.37 0.55 89.24
10 INT239149 Positive_regulation of Coq9 4 0.33 2.96 0.37 83.20
11 INT251830 Binding of TYMP 2 0.13 4.36 0.37 78.60
12 INT288640 Negative_regulation of Gene_expression of St6galnac2 1 0.03 1.72 0 76.48
13 INT188665 Gene_expression of St6galnac2 5 0.06 3.93 1.08 76.48
14 INT860 Regulation of ALB 48 0.60 25.11 8.95 75.00
15 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 75.00
16 INT61315 Positive_regulation of Gene_expression of Coq10a 6 0.42 3.29 2.19 56.88
17 INT288643 Positive_regulation of Negative_regulation of Coq10a 1 0.39 0.76 0 53.40
18 INT306112 Regulation of NDUFV1 1 0.02 1 0 52.92
19 INT228548 Gene_expression of Coq9 12 0.55 4.93 0.4 41.52
20 INT55537 Positive_regulation of Coq10a 22 0.58 8.17 8.33 35.52
21 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 24.84
22 INT134902 Positive_regulation of Tymp 11 0.37 3.06 0.53 16.80
23 INT258606 Gene_expression of Foxn1 1 0.68 0.65 0 13.44
24 INT205196 Gene_expression of Lpar2 18 0.74 12.19 3.49 5.68
25 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
26 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 5.00
27 INT2910 Regulation of Abat 169 0.62 36.95 153.53 5.00
28 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
29 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
30 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 5.00
31 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
32 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 5.00
33 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
34 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
35 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 5.00
36 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 5.00
37 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
38 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 5.00
39 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 5.00
40 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83 5.00
41 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 5.00
42 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
43 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
44 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
45 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7 5.00
46 INT149015 Gene_expression of Tph2 20 0.78 9.45 10.4 5.00
47 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1 5.00
48 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99 5.00
49 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76 5.00
50 INT36960 Gene_expression of vs 33 0.43 20.77 6.97 5.00
51 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
52 INT49212 Negative_regulation of GAD1 23 0.59 22.15 6.54 5.00
53 INT57232 Binding of Casp3 22 0.36 9.42 6.2 5.00
54 INT10100 Binding of ELANE 22 0.47 15.32 5.19 5.00
55 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69 5.00
56 INT51030 Negative_regulation of LMOD1 9 0.44 5.83 4.58 5.00
57 INT36309 Negative_regulation of DIO2 18 0.57 6.42 4.51 5.00
58 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19 5.00
59 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02 5.00
60 INT2397 Gene_expression of Maoa 12 0.77 11.85 3.88 5.00
61 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 5.00
62 INT64 Regulation of Ptpn6 12 0.14 2.45 3.17 5.00
63 INT25674 Positive_regulation of Gene_expression of ELANE 16 0.60 7.46 3.12 5.00
64 INT60554 Binding of Coq10a 30 0.40 7.99 3.02 5.00
65 INT3463 Gene_expression of Igfals 21 0.39 21.1 2.93 5.00
66 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84 5.00
67 INT205596 Negative_regulation of COQ10A 22 0.51 15.61 2.77 5.00
68 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73 5.00
69 INT205594 Gene_expression of COQ10A 19 0.67 12.53 2.56 5.00
70 INT18848 Localization of LMOD1 5 0.69 1 2.49 5.00
71 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26 5.00
72 INT122895 Transcription of DIO2 3 0.52 0.91 1.73 5.00
73 INT44330 Negative_regulation of St6galnac2 3 0.03 1.94 1.6 5.00
74 INT309257 Transcription of LMOD1 3 0.36 1.71 1.57 5.00
75 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55 5.00
76 INT248418 Localization of Tph2 5 0.75 2.45 1.45 5.00
77 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 5.00
78 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 5.00
79 INT124300 Negative_regulation of Sod2 17 0.45 12.54 0.9 5.00
80 INT11198 Negative_regulation of Gclc 3 0.59 0.49 0.87 5.00
81 INT50687 Gene_expression of Aldoc 6 0.78 0.17 0.78 5.00
82 INT309253 Negative_regulation of Transcription of LMOD1 1 0.03 0.2 0.57 5.00
83 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55 5.00
84 INT87741 Localization of Msr1 5 0.60 4.77 0.5 5.00
85 INT309242 Localization of Nat1 1 0.01 0.17 0.42 5.00
86 INT309244 Transcription of HSPA5 1 0.16 2.75 0.36 5.00
87 INT248415 Binding of Tph2 9 0.44 3.88 0.34 5.00
88 INT131674 Negative_regulation of HEXB 3 0.10 3.78 0.32 5.00
89 INT309249 Regulation of OGDHL 1 0.01 0.6 0.3 5.00
90 INT228540 Localization of Coq10a 12 0.63 3.5 0.3 5.00
91 INT309251 Gene_expression of OGDHL 1 0.01 0.64 0.29 5.00
92 INT138556 Positive_regulation of TYMP 23 0.58 12.9 0.28 5.00
93 INT96952 Gene_expression of Gclc 7 0.38 2.08 0.28 5.00
94 INT228545 Regulation of Coq10a 8 0.42 5.62 0.23 5.00
95 INT354726 Binding of Tymp 1 0.30 1.08 0.23 5.00
96 INT211375 Regulation of Gene_expression of TYMP 2 0.43 2.44 0.22 5.00
97 INT268725 Positive_regulation of Negative_regulation of SOD1 3 0.35 2.41 0.1 5.00
98 INT288642 Negative_regulation of Positive_regulation of Snca 1 0.07 0.93 0.09 5.00
99 INT59073 Gene_expression of Nae1 1 0.01 1.22 0.08 5.00
100 INT261026 Localization of Gclc 3 0.36 0.88 0.06 5.00
101 INT261017 Regulation of Gclc 2 0.22 0.88 0.06 5.00
102 INT309245 Binding of SETX 1 0.08 1.98 0.06 5.00
103 INT309246 Localization of ATXN2 1 0.10 1.45 0.03 5.00
104 INT309254 Localization of ATXN1 1 0.09 1.45 0.03 5.00
105 INT309258 Localization of TBP 2 0.27 1.78 0.03 5.00
106 INT164193 Localization of ATN1 2 0.73 1.47 0.03 5.00
107 INT309250 Localization of ATXN3 1 0.14 1.46 0.03 5.00
108 INT228547 Transcription of Coq10a 3 0.58 1.21 0.03 5.00
109 INT309256 Localization of ATXN7 1 0.11 1.46 0.03 5.00
110 INT258603 Localization of Leo1 1 0.04 0 0 5.00
111 INT309255 Gene_expression of NDUFV1 1 0.01 2.33 0 5.00
112 INT258607 Positive_regulation of Positive_regulation of Foxn1 1 0.44 0.06 0 5.00
113 INT306111 Negative_regulation of NDUFA12 1 0.01 1.28 0 5.00
114 INT258609 Transcription of Leo1 1 0.03 0 0 5.00
115 INT258608 Positive_regulation of Localization of Leo1 1 0.02 0 0 5.00
116 INT258605 Negative_regulation of Transcription of Leo1 1 0.02 0 0 5.00
117 INT175738 Regulation of ARNTL 4 0.28 0.29 0 5.00
118 INT309248 Negative_regulation of ATXN8OS 1 0.06 1.49 0 5.00
119 INT258604 Positive_regulation of Foxn1 1 0.44 0.06 0 5.00
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