D:Mobility Limitation

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pChart

Disease Term
Synonyms AMBULATION DIFFICULTY, Ambulatory Difficulty, DIFFICULTY AMBULATION, Difficulty Walking, Limitation Mobility, Mobility Limitations
Documents 145
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mobility Limitation. They are ordered first by their relevance to Mobility Limitation and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
2 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 5.00
3 INT251944 Binding of GH1 and PRNP 1 0.09 1.14 0.05 5.00
4 INT299626 Binding of IGF1 and IGFBP3 Positive_regulation of IGF1 1 0.02 0.39 0 5.00
5 INT299628 MSTN Negative_regulation of Gene_expression of MYOD1 1 0.09 0.15 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mobility Limitation. They are ordered first by their pain relevance and then by number of times they were reported in Mobility Limitation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 94.32
2 INT76479 Binding of CD99 5 0.33 4.66 0.44 89.20
3 INT320985 Positive_regulation of Localization of Pth 1 0.37 1.26 0.08 76.32
4 INT23030 Positive_regulation of Pth 13 0.61 9.24 0.97 75.52
5 INT125804 Localization of Pth 9 0.69 3.93 0.29 75.52
6 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 70.80
7 INT1645 Negative_regulation of CSH1 20 0.42 1.71 3.7 69.60
8 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 68.28
9 INT10059 Binding of CSH1 17 0.35 5.28 3.37 67.04
10 INT146805 Positive_regulation of Gene_expression of Pth 4 0.49 4.2 0.07 66.00
11 INT320988 Regulation of Gc 3 0.13 2.52 0.62 65.64
12 INT70262 Gene_expression of Pth 8 0.66 5.64 0.12 65.20
13 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 63.28
14 INT7090 Gene_expression of pcp 50 0.66 13.54 8.96 57.52
15 INT67138 Gene_expression of Gc 19 0.31 17.11 4.1 47.80
16 INT320989 Phosphorylation of Gc 1 0.07 0.83 0.05 47.44
17 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 46.80
18 INT168565 Positive_regulation of Gc 4 0.13 3.74 1.45 14.84
19 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 14.00
20 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
21 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
22 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
23 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
24 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
25 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
26 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
27 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
28 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
29 INT921 Regulation of GH1 172 0.60 52.88 51.04 5.00
30 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 5.00
31 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
32 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
33 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
34 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
35 INT9355 Binding of pcp 81 0.46 10.41 24.22 5.00
36 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
37 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 5.00
38 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
39 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
40 INT38056 Localization of Crp 71 0.78 53.14 17.03 5.00
41 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
42 INT90766 Gene_expression of PCS 93 0.77 40.48 14.51 5.00
43 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
44 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34 5.00
45 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
46 INT11307 Negative_regulation of pcp 30 0.48 7.86 11.53 5.00
47 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 5.00
48 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
49 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 5.00
50 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 5.00
51 INT62509 Gene_expression of MCS 58 0.67 21.46 6.57 5.00
52 INT49212 Negative_regulation of GAD1 23 0.59 22.15 6.54 5.00
53 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
54 INT53196 Binding of Cd4 44 0.47 27.28 5.85 5.00
55 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 5.00
56 INT73117 Positive_regulation of DNMT3B 20 0.47 10.31 5.31 5.00
57 INT99091 Regulation of AR 70 0.45 31.68 5.05 5.00
58 INT19900 Binding of GHRH 22 0.37 5.75 5 5.00
59 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63 5.00
60 INT5205 Localization of AR 43 0.80 12.87 4.63 5.00
61 INT22145 Binding of Sugt1 16 0.13 8.31 4.37 5.00
62 INT2936 Gene_expression of AGL 36 0.49 9.55 3.63 5.00
63 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 5.00
64 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 5.00
65 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 5.00
66 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
67 INT22500 Negative_regulation of Pth 6 0.43 3.41 2.83 5.00
68 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73 5.00
69 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
70 INT1643 Regulation of CSH1 10 0.26 2.45 2.53 5.00
71 INT183668 Binding of SGCA 15 0.36 9.86 2.42 5.00
72 INT70987 Binding of RAC1 14 0.37 12.14 2.13 5.00
73 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97 5.00
74 INT167203 Binding of PRNP 25 0.48 20.09 1.84 5.00
75 INT201810 Gene_expression of LEFTY2 6 0.56 3.94 1.74 5.00
76 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73 5.00
77 INT4395 Positive_regulation of CSH1 20 0.50 6.27 1.52 5.00
78 INT36148 Binding of GAD1 10 0.41 7.91 1.47 5.00
79 INT213750 Positive_regulation of NHS 14 0.59 2.17 1.43 5.00
80 INT161276 Regulation of NHS 7 0.38 1.43 1.4 5.00
81 INT57425 Binding of MYH14 12 0.11 2.33 1.26 5.00
82 INT85621 Regulation of PRNP 16 0.60 8.7 1.15 5.00
83 INT105618 Binding of SEPHS1 4 0.27 5.62 1.14 5.00
84 INT90240 Gene_expression of MYOG 19 0.75 10 1.06 5.00
85 INT253957 Gene_expression of THRA 14 0.58 7.07 0.97 5.00
86 INT67135 Binding of Gc 5 0.10 3.2 0.94 5.00
87 INT294932 Negative_regulation of Gc 6 0.17 3.38 0.71 5.00
88 INT262060 Positive_regulation of Vdr 8 0.58 2.84 0.67 5.00
89 INT179130 Negative_regulation of Binding of Cd4 1 0.42 1.57 0.66 5.00
90 INT245648 Gene_expression of SEPHS1 5 0.49 4.53 0.59 5.00
91 INT137858 Binding of NHS 14 0.32 2.94 0.57 5.00
92 INT146784 Gene_expression of MYOD1 13 0.74 4.41 0.54 5.00
93 INT27765 Gene_expression of MYH14 12 0.65 2.36 0.48 5.00
94 INT299631 Binding of CR2 2 0.12 1.9 0.47 5.00
95 INT80664 Phosphorylation of G6PD 3 0.08 0.58 0.3 5.00
96 INT198851 Gene_expression of MARK3 3 0.65 2.55 0.28 5.00
97 INT309915 Negative_regulation of F2RL3 2 0.01 2.06 0.27 5.00
98 INT189326 Positive_regulation of CTTN 2 0.43 1.17 0.2 5.00
99 INT309916 Negative_regulation of NR2F2 1 0.02 0.7 0.18 5.00
100 INT175834 Localization of SARS 6 0.39 6.23 0.17 5.00
101 INT217658 Negative_regulation of MSTN 4 0.30 1.35 0.17 5.00
102 INT160641 Transcription of Vdr 5 0.71 3.1 0.16 5.00
103 INT180389 Gene_expression of SARS2 1 0.47 2.88 0.14 5.00
104 INT282160 Regulation of Binding of RAC1 1 0.18 0.45 0.13 5.00
105 INT153782 Localization of SEPHS1 2 0.62 0.9 0.12 5.00
106 INT48615 Positive_regulation of Binding of IGF1 5 0.50 0.54 0.11 5.00
107 INT299635 Positive_regulation of IMMT 1 0.01 0 0.1 5.00
108 INT320983 Negative_regulation of Localization of Pth 2 0.38 1.17 0.09 5.00
109 INT90244 Gene_expression of MYF5 3 0.52 0.42 0.06 5.00
110 INT279527 Regulation of Binding of SGCA 1 0.44 0.62 0.05 5.00
111 INT289036 Negative_regulation of Sat1 2 0.46 0.34 0.04 5.00
112 INT299630 Negative_regulation of Gene_expression of MYOD1 1 0.16 0.15 0 5.00
113 INT320984 Localization of Gc 1 0.08 0 0 5.00
114 INT217654 Gene_expression of MSTN 11 0.60 4.41 0 5.00
115 INT194983 Gene_expression of INPP5J 6 0.40 0.22 0 5.00
116 INT217660 Regulation of MSTN 2 0.14 0.49 0 5.00
117 INT299634 Positive_regulation of Gene_expression of MSTN 1 0.35 0.6 0 5.00
118 INT174891 Negative_regulation of NHS 6 0.36 1.16 0 5.00
119 INT320987 Transcription of Gc 1 0.07 0.36 0 5.00
120 INT217659 Regulation of Gene_expression of MSTN 4 0.31 1.15 0 5.00
121 INT223836 Protein_catabolism of INPP5J 1 0.10 0 0 5.00
122 INT189327 Localization of CTTN 1 0.65 0.6 0 5.00
123 INT320986 Negative_regulation of Localization of Gc 1 0.04 0 0 5.00
124 INT299633 Negative_regulation of Gene_expression of MYOG 1 0.16 0.15 0 5.00
125 INT180391 Regulation of SARS2 1 0.19 0.79 0 5.00
126 INT251948 Binding of PRND 1 0.35 0.86 0 5.00
127 INT189328 Regulation of Localization of CTTN 1 0.39 0.6 0 5.00
128 INT180392 Positive_regulation of SARS2 1 0.32 0.9 0 5.00
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