D:Mononeuropathies

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Disease Term
Synonyms Mononeuritides, Mononeuritis, Mononeuritis Multiplex, Mononeuropathy, Mononeuropathy Multiplex, Mononeuropathy Multiplex Syndrome, MONONEUROPATHY MULTIPLEX SYNDROMES, Syndrome Mononeuropathy Multiplex, SYNDROMES MONONEUROPATHY MULTIPLEX
Documents 267
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mononeuropathies. They are ordered first by their relevance to Mononeuropathies and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61 5.00
2 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53 5.00
3 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45 5.00
4 INT172004 IL17A Positive_regulation of Gene_expression of IL6 2 0.14 1.35 0.34 5.00
5 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25 5.00
6 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 5.00
7 INT249666 Binding of CD81 and GOPC 1 0.06 1.31 0 5.00
8 INT249664 Binding of CD81 and CHCHD2 1 0.00 2.51 0 5.00
9 INT172011 IgG Regulation of Ighm 1 0.00 0.77 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mononeuropathies. They are ordered first by their pain relevance and then by number of times they were reported in Mononeuropathies. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2925 Positive_regulation of Positive_regulation of Mpo 21 0.70 16.76 6.36 100.00
2 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 99.66
3 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 99.48
4 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.48
5 INT153495 Binding of Pmp22 3 0.37 2.51 0.34 97.20
6 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 97.16
7 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 95.32
8 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 93.72
9 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 92.88
10 INT142735 Regulation of RLS 33 0.53 45.83 11.35 91.96
11 INT153496 Negative_regulation of Pmp22 2 0.42 3.34 0.26 91.92
12 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 88.96
13 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 86.72
14 INT110210 Negative_regulation of CSRP1 12 0.59 8.96 2.81 81.12
15 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 81.00
16 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 80.28
17 INT11867 Positive_regulation of Positive_regulation of TAT 2 0.49 2.02 0.54 79.64
18 INT8866 Positive_regulation of TAT 30 0.67 18.06 5.57 79.64
19 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 76.68
20 INT111255 Transcription of Gnb5 3 0.66 2.81 1.66 76.44
21 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 73.08
22 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 68.08
23 INT19763 Gene_expression of CTs 69 0.78 32.92 18.87 65.64
24 INT49610 Positive_regulation of Gene_expression of CTS 7 0.43 7.45 3.58 65.64
25 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 64.88
26 INT111263 Gene_expression of Gnb5 8 0.75 8.51 3 63.24
27 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 60.64
28 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 60.64
29 INT77523 Positive_regulation of ADC 14 0.63 13.81 1.81 55.28
30 INT111199 Gene_expression of Acly 11 0.16 5.65 0.78 54.92
31 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32 54.92
32 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 50.48
33 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 49.84
34 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 49.44
35 INT58038 Binding of Drb1 5 0.22 3.42 3 48.28
36 INT66077 Regulation of CHPT1 12 0.38 6.1 3.23 46.52
37 INT117172 Regulation of Hpt 7 0.41 3.39 0.52 46.20
38 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 40.40
39 INT27495 Positive_regulation of IGLV2-14 1 0.67 3.28 0.34 40.40
40 INT59010 Positive_regulation of Regulation of Crp 2 0.27 2.11 1.09 33.92
41 INT37390 Regulation of Crp 39 0.46 28.74 11.45 33.52
42 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 31.96
43 INT168373 Gene_expression of Capns1 4 0.58 4.55 1.34 26.80
44 INT281008 Negative_regulation of Gene_expression of Capns1 1 0.03 1.79 0.04 26.80
45 INT164512 Regulation of MPZ 12 0.30 8.38 1.53 12.76
46 INT144613 Regulation of NEFL 2 0.31 1.55 0.07 12.76
47 INT286054 Regulation of GJB1 1 0.08 1.04 0.07 12.76
48 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 6.96
49 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
50 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 5.00
51 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
52 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 5.00
53 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
54 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
55 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
56 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 5.00
57 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
58 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
59 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
60 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
61 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
62 INT22454 Regulation of Crp 213 0.62 160.67 49.24 5.00
63 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
64 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
65 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
66 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
67 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
68 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 5.00
69 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
70 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
71 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 5.00
72 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
73 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
74 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
75 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 5.00
76 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
77 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
78 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
79 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52 5.00
80 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 5.00
81 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 5.00
82 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 5.00
83 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
84 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
85 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 5.00
86 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
87 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65 5.00
88 INT19399 Gene_expression of Rf 43 0.36 33.39 13.53 5.00
89 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 5.00
90 INT35801 Regulation of Alms1 34 0.38 20.88 12.38 5.00
91 INT120828 Localization of CXCL10 29 0.68 18.01 12.17 5.00
92 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 5.00
93 INT19428 Gene_expression of MTRF1 42 0.08 27.17 10.43 5.00
94 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 5.00
95 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 5.00
96 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
97 INT11146 Negative_regulation of CTS 26 0.51 10.33 8.77 5.00
98 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 5.00
99 INT75932 Binding of Csf2 45 0.37 33.2 8.01 5.00
100 INT121752 Gene_expression of IL11 54 0.62 18.05 7.16 5.00
101 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 5.00
102 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 5.00
103 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 5.00
104 INT177467 Negative_regulation of MTRF1 22 0.05 11.84 5.57 5.00
105 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 5.00
106 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36 5.00
107 INT24741 Positive_regulation of Rf 16 0.17 18.23 4.75 5.00
108 INT35254 Negative_regulation of SERPINB1 22 0.48 11.42 4.7 5.00
109 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 5.00
110 INT9837 Negative_regulation of Rf 12 0.11 8.41 4.55 5.00
111 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 5.00
112 INT127667 Positive_regulation of Localization of CXCL10 5 0.59 5.89 4.09 5.00
113 INT24231 Localization of SERPINB1 13 0.61 3.1 3.61 5.00
114 INT78203 Gene_expression of PMP22 12 0.63 7.49 3.58 5.00
115 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 5.00
116 INT150395 Binding of MEFV 55 0.44 31.18 3.42 5.00
117 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 5.00
118 INT80007 Transcription of GRIN1 5 0.67 2.36 3.26 5.00
119 INT14086 Binding of SERPINB1 18 0.34 4.32 3.13 5.00
120 INT37193 Negative_regulation of BDNF-AS 21 0.37 15.06 3.12 5.00
121 INT43907 Binding of CD79A 28 0.48 28.11 3.04 5.00
122 INT237655 Binding of Sfn 1 0.42 3.62 2.55 5.00
123 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 5.00
124 INT139169 Gene_expression of Pmp22 10 0.68 8.37 2.5 5.00
125 INT34830 Regulation of PGR 14 0.45 6.99 2.32 5.00
126 INT237653 Gene_expression of Sfn 6 0.59 5.54 2.26 5.00
127 INT97308 Gene_expression of TPO 15 0.65 13.26 2.12 5.00
128 INT16452 Negative_regulation of SERPIND1 13 0.59 8.43 1.83 5.00
129 INT108913 Positive_regulation of HAL 10 0.28 5.71 1.59 5.00
130 INT29898 Negative_regulation of C6orf25 16 0.29 9.58 1.33 5.00
131 INT67254 Gene_expression of RPLP0 6 0.38 2.7 1.24 5.00
132 INT116362 Positive_regulation of C4A 17 0.69 11.53 1.03 5.00
133 INT19431 Positive_regulation of Gene_expression of MTRF1 5 0.05 3.13 0.95 5.00
134 INT98409 Binding of Rf 4 0.08 3.97 0.94 5.00
135 INT210276 Positive_regulation of Gene_expression of PMP22 3 0.46 1.58 0.88 5.00
136 INT15870 Regulation of PSS 6 0.25 3.22 0.85 5.00
137 INT102353 Positive_regulation of HLA-DQA2 6 0.06 4.07 0.82 5.00
138 INT21604 Localization of BDNF-AS 12 0.73 9.5 0.79 5.00
139 INT87458 Binding of CD81 4 0.18 6.02 0.59 5.00
140 INT237075 Gene_expression of Spn 5 0.42 5.18 0.56 5.00
141 INT103638 Negative_regulation of MEFV 7 0.39 5.88 0.54 5.00
142 INT254248 Regulation of Rf 2 0.16 0.46 0.53 5.00
143 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5 5.00
144 INT237651 Negative_regulation of Sfn 3 0.51 1.7 0.49 5.00
145 INT237652 Positive_regulation of Sfn 3 0.49 1.17 0.27 5.00
146 INT310703 Negative_regulation of Gene_expression of RPLP0 1 0.04 0.68 0.21 5.00
147 INT252157 Negative_regulation of Spn 3 0.08 2.36 0.12 5.00
148 INT192069 Localization of Acly 1 0.02 0.84 0 5.00
149 INT249680 Binding of CHCHD2 1 0.01 2.45 0 5.00
150 INT192070 Positive_regulation of Localization of Acly 1 0.02 0.84 0 5.00
151 INT247403 Negative_regulation of Gene_expression of SERPINB1 1 0.01 0.77 0 5.00
152 INT285398 Positive_regulation of HLA-DRB8 1 0.01 1.11 0 5.00
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