D:Mouth Disease

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Disease Term
Synonyms Dental Anomalies, Dental Caries, DISEASE MOUTH, Diseases Mouth, Gingival Disease, Gingivitis, Halitosis, Mouth Diseases, Mouth Disorder, MOUTH DISORDERS, MOUTH DYSFUNCTION
Documents 382
Hot Single Events 115
Hot Interactions 21

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mouth Disease. They are ordered first by their relevance to Mouth Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329004 Binding of MPZ and RNF123 1 0.00 0.7 0 100.00
2 INT329012 Binding of MPZ and Nedd4 1 0.03 0.7 0 100.00
3 INT329007 Binding of MPZ and TSG101 1 0.01 0.71 0 100.00
4 INT164249 Binding of MPZ and Mpz 1 0.06 2.13 0.24 100.00
5 INT311046 Binding of CSF2 and IL33 1 0.00 1.86 0.26 99.92
6 INT329013 Binding of LITAF and Nedd4 1 0.15 1.4 0 99.88
7 INT329008 Binding of LITAF and RNF123 1 0.01 1.39 0 99.88
8 INT329005 Binding of TSG101 and LITAF 1 0.04 1.41 0 99.88
9 INT311268 RENBP Regulation of Gene_expression of IL8 1 0.02 1.05 0.24 95.92
10 INT311267 RENBP Regulation of Gene_expression of TNF 1 0.02 0.54 0.09 95.92
11 INT311263 RENBP Regulation of TNF 1 0.01 1.59 0.33 95.56
12 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63 95.56
13 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 95.56
14 INT311265 RENBP Regulation of IL8 1 0.03 1.59 0.33 95.24
15 INT311266 RENBP Regulation of IL6 1 0.02 1.59 0.32 95.00
16 INT329341 UCN2 Positive_regulation of THAS 1 0.00 1.12 0 94.28
17 INT329340 UCN2 Positive_regulation of SOD1 1 0.02 1.12 0 93.96
18 INT165324 Binding of TRPV4 and Trpv4 1 0.11 0.66 0.1 93.92
19 INT234831 Binding of SPTLC1 and Abo 1 0.00 1.61 0.23 91.60
20 INT311262 RENBP Regulation of Regulation of TNF 1 0.02 0.33 0.13 88.00
21 INT141317 Binding of Fbln5 and Olfr74 1 0.00 0.31 0.09 87.04
22 INT329342 Binding of THAS and LRRFIP1 1 0.00 0.97 0.09 78.24
23 INT194324 Binding of MPZ and MAD2L1BP 1 0.02 0.62 0.04 77.80
24 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 66.72
25 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15 65.88
26 INT283543 Binding of GARS and Setx 1 0.01 3.71 0 63.44
27 INT283542 Binding of SPG19 and Setx 1 0.06 3.69 0 63.44
28 INT298873 RAB7A Regulation of Protein_catabolism of NTRK1 1 0.12 0.25 0.03 62.72
29 INT283533 Binding of GARS and SPG19 1 0.00 1.72 0 57.24
30 INT194333 Binding of MFN2 and Racgap1 1 0.01 0.38 0 57.04
31 INT298872 RAB7A Regulation of Protein_catabolism of GFM1 1 0.47 0.22 0.03 56.08
32 INT311264 IL6 Positive_regulation of Gene_expression of PPIAP10 1 0.30 0.98 0.36 50.00
33 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 45.04
34 INT283539 Binding of Litaf and Mad2l1bp 1 0.00 0.67 0.11 40.92
35 INT203406 Cap2 Negative_regulation of Rtn4 1 0.07 0.59 0 28.84
36 INT203409 Cap2 Negative_regulation of Bex1 1 0.07 0.58 0 28.84
37 INT203408 Vsnl1 Negative_regulation of Cap2 1 0.15 0.58 0 28.84
38 INT203407 Cap2 Negative_regulation of Nptn 1 0.06 0.59 0 28.84
39 INT203413 Cap2 Negative_regulation of Rtn1 1 0.06 0.59 0 28.84
40 INT203404 Cap2 Negative_regulation of Chn1 1 0.06 0.58 0 28.84
41 INT203402 Enc1 Negative_regulation of Rtn1 1 0.07 0.58 0 28.60
42 INT203418 Enc1 Negative_regulation of Rtn4 1 0.08 0.58 0 28.60
43 INT203398 Enc1 Negative_regulation of Nptn 1 0.07 0.59 0 28.60
44 INT203397 Enc1 Negative_regulation of Chn1 1 0.08 0.58 0 28.60
45 INT203403 Enc1 Negative_regulation of Bex1 1 0.08 0.58 0 28.60
46 INT203411 Mllt11 Negative_regulation of Nptn 1 0.08 0.58 0 28.36
47 INT203417 Mllt11 Negative_regulation of Rtn1 1 0.08 0.58 0 28.36
48 INT203416 Mllt11 Negative_regulation of Chn1 1 0.09 0.58 0 28.36
49 INT203393 Mllt11 Negative_regulation of Bex1 1 0.09 0.58 0 28.36
50 INT203396 Mllt11 Negative_regulation of Rtn4 1 0.09 0.58 0 28.36
51 INT203400 Olfm1 Negative_regulation of Bex1 1 0.09 0.58 0 28.04
52 INT203415 Olfm1 Negative_regulation of Chn1 1 0.08 0.58 0 28.04
53 INT203392 Olfm1 Negative_regulation of Nptn 1 0.08 0.58 0 28.04
54 INT203399 Olfm1 Negative_regulation of Rtn4 1 0.09 0.58 0 28.04
55 INT203391 Olfm1 Negative_regulation of Rtn1 1 0.08 0.58 0 28.04
56 INT203405 Vsnl1 Negative_regulation of Bex1 1 0.19 0.58 0 27.76
57 INT203414 Vsnl1 Negative_regulation of Nptn 1 0.16 0.58 0 27.76
58 INT203394 Vsnl1 Negative_regulation of Chn1 1 0.17 0.58 0 27.76
59 INT203410 Vsnl1 Negative_regulation of Rtn4 1 0.18 0.58 0 27.76
60 INT203401 Vsnl1 Negative_regulation of Rtn1 1 0.17 0.58 0 27.76
61 INT238805 Binding of DSP and HSPB2 1 0.09 4.2 0.13 15.60
62 INT234795 Negative_regulation of CHM Negative_regulation of RAB27A 1 0.01 0.8 0 12.88
63 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
64 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16 5.00
65 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 5.00
66 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 5.00
67 INT275851 PES1 Negative_regulation of CP 1 0.01 1.96 1.83 5.00
68 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
69 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
70 INT344973 Negative_regulation of Mmp23 Regulation of Negative_regulation of Mag 1 0.01 1.14 0.99 5.00
71 INT344974 Lpar1 Regulation of Gene_expression of Mag 1 0.25 0.98 0.76 5.00
72 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42 5.00
73 INT285598 Maoa Negative_regulation of Aldh3a1 1 0.01 0.18 0.36 5.00
74 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35 5.00
75 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25 5.00
76 INT173405 Binding of FCGR3B and Itgam 1 0.06 0.65 0.23 5.00
77 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22 5.00
78 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2 5.00
79 INT285604 ROS1 Positive_regulation of Gene_expression of Tlr4 1 0.01 1.14 0.2 5.00
80 INT173396 GPER Negative_regulation of Binding of FCGR3B and Itgam 1 0.01 0.48 0.19 5.00
81 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17 5.00
82 INT285605 Binding of ROS1 and Tlr4 1 0.01 1.25 0.16 5.00
83 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16 5.00
84 INT233386 Binding of Il12a and Il12b 1 0.01 0.48 0.15 5.00
85 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15 5.00
86 INT237442 Ass1 Positive_regulation of S100b 1 0.00 0.18 0.13 5.00
87 INT173404 GPER Regulation of Itgam 1 0.02 0.41 0.13 5.00
88 INT173406 Binding of ITGAL and Itgb2 1 0.02 0.41 0.13 5.00
89 INT173373 GPER Regulation of FCGR3B 1 0.03 0.39 0.12 5.00
90 INT241748 CCR5 Regulation of CD4 1 0.21 0.39 0.11 5.00
91 INT233384 Il10 Negative_regulation of Il12a 1 0.01 0.54 0.11 5.00
92 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
93 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
94 INT173371 GPER Regulation of ITGAL 1 0.01 0.23 0.08 5.00
95 INT173408 GPER Regulation of Itgb2 1 0.01 0.23 0.08 5.00
96 INT173376 GPER Regulation of ITGAX 1 0.00 0.23 0.08 5.00
97 INT285602 Trib3 Regulation of Gene_expression of Nos2 1 0.00 0.48 0.07 5.00
98 INT173372 GPER Regulation of Binding of FCGR3B 1 0.03 0.21 0.07 5.00
99 INT203419 Binding of EIF4A1 and Gtf3a 1 0.00 0.5 0.07 5.00
100 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07 5.00
101 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07 5.00
102 INT173400 Negative_regulation of Binding of GPER and Itgam 1 0.01 0.19 0.06 5.00
103 INT173407 Binding of GPER and Itgam 1 0.01 0.26 0.06 5.00
104 INT311296 Akt1 Positive_regulation of Gene_expression of Clcn1 1 0.11 0 0.05 5.00
105 INT241751 Negative_regulation of Binding of CD4 and ITIH4 3 0.18 1.07 0.04 5.00
106 INT173379 Binding of Itgam and Ns5atp9 1 0.01 0.18 0.04 5.00
107 INT241752 ITIH4 Negative_regulation of Binding of CXCR4 1 0.08 0.71 0.04 5.00
108 INT173397 GPER Negative_regulation of Binding of GPER and Ns5atp9 1 0.00 0.18 0.04 5.00
109 INT241749 ITIH4 Negative_regulation of Binding of CCR5 1 0.16 0.71 0.04 5.00
110 INT173374 GPER Negative_regulation of Binding of FCGR3B 1 0.03 0.16 0.04 5.00
111 INT285603 Akt1 Regulation of Gene_expression of Nos2 1 0.02 0.48 0.04 5.00
112 INT173403 GPER Negative_regulation of Binding of Itgam 1 0.01 0.15 0.04 5.00
113 INT173399 Binding of GPER and Ns5atp9 1 0.00 0.18 0.04 5.00
114 INT173402 Binding of FCGR3B and Ns5atp9 1 0.02 0.18 0.04 5.00
115 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03 5.00
116 INT298831 Binding of MTOR and RAB7A Positive_regulation of MTOR 1 0.02 0.35 0.03 5.00
117 INT298878 Binding of MTOR and RAB7A 1 0.07 0.35 0.03 5.00
118 INT310804 SFTPA1 Negative_regulation of Gene_expression of Ptges2 1 0.00 0.14 0.03 5.00
119 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
120 INT298858 Positive_regulation of Binding of VAPA and RILP 1 0.07 0.54 0 5.00
121 INT298854 Binding of LAMP2 and RAB7A 1 0.16 0.56 0 5.00
122 INT298862 Binding of MCC and VPS13C 1 0.00 0.36 0 5.00
123 INT298879 Binding of MCC and MTG1 1 0.00 0.37 0 5.00
124 INT311298 Binding of DMPK and Mbnl1 1 0.43 0.54 0 5.00
125 INT311295 Gopc Positive_regulation of Gene_expression of Clcn1 1 0.07 0.29 0 5.00
126 INT233387 Binding of SPINK1 and Il12b 1 0.04 0.33 0 5.00
127 INT211779 Binding of EIF4G1 and NTSR1 1 0.02 0 0 5.00
128 INT211781 Binding of NTSR1 and RDBP 1 0.00 0.42 0 5.00
129 INT298863 Binding of VAPB and RILP 1 0.13 0.21 0 5.00
130 INT211777 Binding of NTSR1 and PTBP1 1 0.03 0.82 0 5.00
131 INT298875 Binding of RAB7A and VPS13C 1 0.21 0.49 0 5.00
132 INT268331 Binding of SNRNP70 and CHD7 1 0.01 1.91 0 5.00
133 INT173375 Binding of FCGR3B and GPER 1 0.02 0 0 5.00
134 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0 5.00
135 INT298845 VAPA Regulation of Negative_regulation of RAB7A 1 0.12 0.32 0 5.00
136 INT234800 RAB27A Positive_regulation of INS 1 0.02 1.26 0 5.00
137 INT298868 Binding of RAB7A and GOPC 1 0.07 1.64 0 5.00
138 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0 5.00
139 INT173378 Ns5atp9 Positive_regulation of Mfi2 1 0.00 0.43 0 5.00
140 INT173380 Ns5atp9 Positive_regulation of Binding of Itgam 1 0.01 0.43 0 5.00
141 INT298848 Binding of SPG21 and RILP 1 0.10 0.21 0 5.00
142 INT211780 Binding of AHSA1 and PLVAP 1 0.01 0 0 5.00
143 INT298849 Binding of APOB and MCC 1 0.00 0.38 0 5.00
144 INT298859 Positive_regulation of Binding of MCC and VPS13C 1 0.01 0.36 0 5.00
145 INT211776 Binding of PTBP2 and PLVAP 1 0.05 0.43 0 5.00
146 INT298853 Binding of AGFG1 and RILP 1 0.02 0.21 0 5.00
147 INT298856 Binding of APOB and MTG1 1 0.00 0.38 0 5.00
148 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0 5.00
149 INT298866 Binding of AGFG1 and RAB7A 1 0.04 0.21 0 5.00
150 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 5.00
151 INT283062 ERCC8 Positive_regulation of CFH 1 0.02 1.88 0 5.00
152 INT298846 Binding of MCC and RILP 1 0.01 0.36 0 5.00
153 INT264679 IGFALS Positive_regulation of CTSC 1 0.02 1.68 0 5.00
154 INT267136 Binding of CD44 and FN1 2 0.04 0.56 0 5.00
155 INT298850 Binding of RAB7A and MTG1 1 0.01 0.24 0 5.00
156 INT234790 B4GALNT1 Positive_regulation of AGFG1 1 0.00 0.08 0 5.00
157 INT298877 Positive_regulation of Binding of RAB7A and VPS13C 1 0.22 0.49 0 5.00
158 INT308030 Binding of Mpz and ASPM 1 0.02 0.55 0 5.00
159 INT298851 Binding of IK and RAB7A 1 0.02 0.57 0 5.00
160 INT234793 RAB27A Positive_regulation of Localization of INS 1 0.03 1.26 0 5.00
161 INT352482 Binding of PCA and Uncx 1 0.00 0.06 0 5.00
162 INT310805 MAPK8 Regulation of Regulation of Ptges2 1 0.01 0 0 5.00
163 INT234803 AVP Regulation of AQP2 1 0.11 1.3 0 5.00
164 INT264678 Binding of SETX and KRT20 1 0.00 2.17 0 5.00
165 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0 5.00
166 INT298871 ALOX5AP Positive_regulation of RAB7A 1 0.09 0.35 0 5.00
167 INT173370 GPER Regulation of Binding of FCGR3B and GPER 1 0.00 0 0 5.00
168 INT298869 Binding of RAB7A and RILP 1 0.25 1.07 0 5.00
169 INT298857 Binding of RILP and MTG1 1 0.01 0.35 0 5.00
170 INT173398 GPER Regulation of Binding of Itgam 1 0.01 0 0 5.00
171 INT298855 Positive_regulation of Binding of MCC and MTG1 1 0.00 0.37 0 5.00
172 INT234791 Binding of AVP and AVPR2 1 0.14 0.55 0 5.00
173 INT283544 Binding of GARS and Bscl2 1 0.01 1.74 0 5.00
174 INT234794 Binding of GDI1 and AGFG1 1 0.01 0 0 5.00
175 INT308029 ASPM Positive_regulation of Regulation of Mpz 1 0.02 0.55 0 5.00
176 INT298865 Positive_regulation of Binding of RILP and MTG1 1 0.01 0.35 0 5.00
177 INT173381 Binding of Itgam and Mfi2 1 0.01 0 0 5.00
178 INT298847 Binding of VAPA and RILP 1 0.05 0.54 0 5.00
179 INT234796 Binding of AQP2 and AVP 1 0.15 1.1 0 5.00
180 INT298852 Binding of AGFG1 and MTG1 1 0.00 0 0 5.00
181 INT234797 AVP Regulation of GOPC 1 0.01 0.65 0 5.00
182 INT298864 VAPB Regulation of Negative_regulation of RAB7A 1 0.32 0.32 0 5.00
183 INT298861 Binding of APOB and RAB7A 1 0.00 0.32 0 5.00
184 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 5.00
185 INT298870 Binding of PDB1 and RAB7A 1 0.51 0.21 0 5.00
186 INT264682 Binding of VAPB and SETX 1 0.28 1.09 0 5.00
187 INT211778 Binding of PCBP1 and PLVAP 1 0.07 0 0 5.00
188 INT173401 Binding of GPER and Fn1 1 0.00 0.48 0 5.00
189 INT210285 Ccrs1 Regulation of RAI1 1 0.00 0.37 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mouth Disease. They are ordered first by their pain relevance and then by number of times they were reported in Mouth Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT151878 Gene_expression of CAV2 18 0.66 9.26 2.17 100.00
2 INT114330 Binding of MPZ 21 0.32 25.58 2.14 100.00
3 INT164248 Positive_regulation of MPZ 18 0.67 24.54 2.16 100.00
4 INT141316 Binding of Olfr74 1 0.01 0.4 0.18 100.00
5 INT329009 Phosphorylation of MPZ 1 0.04 0.29 0 100.00
6 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 99.96
7 INT99176 Positive_regulation of Fap 4 0.13 7.5 0.22 99.92
8 INT242822 Transcription of Fap 1 0.18 1.2 0 99.92
9 INT178547 Gene_expression of CSTB 9 0.29 6.53 0.18 99.92
10 INT204929 Binding of IL33 18 0.08 4.74 0.7 99.74
11 INT211361 Regulation of RENBP 5 0.08 2.8 0.38 99.48
12 INT49082 Gene_expression of MPZ 15 0.65 31.26 2.24 99.28
13 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.02
14 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 99.00
15 INT151095 Gene_expression of ATP6V0A1 13 0.48 4.4 1.37 99.00
16 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 98.98
17 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 98.98
18 INT85624 Gene_expression of GJB1 5 0.78 3.03 0.93 98.76
19 INT175214 Gene_expression of HSPB2 21 0.72 22.84 0.81 98.76
20 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 98.52
21 INT335833 Localization of LRRFIP1 1 0.25 0.56 0.09 98.36
22 INT335828 Regulation of Gene_expression of LRRFIP1 1 0.15 0.53 0.08 98.32
23 INT30061 Negative_regulation of Hdc 8 0.59 2.14 2.27 98.30
24 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55 98.28
25 INT6484 Binding of IL1B 122 0.47 75.84 35.07 98.16
26 INT114911 Positive_regulation of Mpz 3 0.23 1.46 0.8 98.16
27 INT335829 Protein_catabolism of LRRFIP1 1 0.29 0.56 0.09 97.92
28 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 97.84
29 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19 97.80
30 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 97.56
31 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.52
32 INT164920 Gene_expression of IL33 22 0.76 13.63 3.16 97.52
33 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 97.44
34 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 97.20
35 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 97.12
36 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 97.04
37 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 96.92
38 INT201261 Regulation of AGFG1 4 0.09 2.72 0.9 96.92
39 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 96.84
40 INT194327 Positive_regulation of GDAP1 1 0.35 0.68 0 96.64
41 INT10141 Gene_expression of A2M 11 0.35 9.37 2.75 96.60
42 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 96.28
43 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 96.28
44 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 96.28
45 INT54662 Positive_regulation of Positive_regulation of Il1 21 0.43 19.33 7.14 96.28
46 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 95.88
47 INT13354 Transcription of TNF 108 0.72 85.81 42.32 95.88
48 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58 95.88
49 INT335830 Gene_expression of LRRFIP1 1 0.22 2.43 0.38 95.72
50 INT51444 Regulation of PMP22 2 0.44 1.39 0.07 95.72
51 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 95.28
52 INT222884 Negative_regulation of Transcription of Il1 3 0.05 2.68 0.49 95.00
53 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 95.00
54 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 94.96
55 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 94.92
56 INT91664 Positive_regulation of Negative_regulation of IL8 5 0.40 3.28 1.62 94.92
57 INT329010 Protein_catabolism of LITAF 1 0.11 1.06 0 94.68
58 INT329011 Protein_catabolism of RAB7A 1 0.07 1.06 0 94.68
59 INT31616 Protein_catabolism of DNM2 5 0.75 1.61 1.63 94.68
60 INT51445 Binding of B3GAT1 9 0.47 4.64 3.95 94.56
61 INT59321 Transcription of Il1 13 0.50 9.73 2.68 94.48
62 INT335832 Gene_expression of NIPSNAP3A 1 0.04 0.39 0.11 94.08
63 INT30885 Positive_regulation of Nefl 6 0.36 6.99 0.9 94.04
64 INT156301 Regulation of Trpv4 11 0.60 2.81 2.35 93.92
65 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 92.88
66 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 92.88
67 INT132853 Gene_expression of GCFC2 2 0.58 1.06 0.41 92.24
68 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 92.04
69 INT57163 Gene_expression of AGFG1 11 0.75 2.45 0.48 91.92
70 INT121918 Binding of Rab7 1 0.34 0.64 0.09 91.92
71 INT273005 Negative_regulation of IL33 4 0.07 2.4 0.38 91.76
72 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 91.76
73 INT258726 Positive_regulation of Nfxl1 1 0.05 1.89 0.18 91.52
74 INT59083 Positive_regulation of Gene_expression of IL1A 11 0.70 9.09 4.48 91.36
75 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57 91.36
76 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05 91.32
77 INT175225 Positive_regulation of Gene_expression of HSPB2 2 0.65 3.57 0.06 91.04
78 INT64965 Binding of AGFG1 8 0.10 3.53 0.45 90.80
79 INT283541 Binding of GARS 1 0.01 3.33 0.04 90.16
80 INT173386 Localization of CYLC2 1 0.01 0.4 0.1 89.68
81 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 89.36
82 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 89.36
83 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 89.36
84 INT213672 Positive_regulation of LRFN2 1 0.01 0.59 0.03 89.20
85 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 88.68
86 INT22605 Regulation of Pgr 22 0.62 7.1 2.26 88.60
87 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 88.52
88 INT213671 Positive_regulation of COX4I1 1 0.00 0.58 0.03 88.08
89 INT9660 Regulation of TNF 363 0.62 312.94 139.99 88.00
90 INT213669 Positive_regulation of COL4A3 2 0.00 1.24 0.23 87.60
91 INT28817 Binding of TRPV4 6 0.39 3.92 2.59 86.96
92 INT287525 Localization of CAV2 5 0.47 5.32 2 86.56
93 INT68952 Localization of PCNA 17 0.62 5.64 1.78 86.40
94 INT238807 Localization of HSPB2 1 0.75 2.27 0.04 85.84
95 INT176264 Binding of PCNA 21 0.21 9.08 0.51 85.76
96 INT49486 Gene_expression of Cma1 6 0.52 4.17 1.13 85.36
97 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 84.92
98 INT116516 Positive_regulation of GCFC2 5 0.49 2.83 2.17 84.88
99 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 84.88
100 INT81140 Gene_expression of CYTIP 5 0.65 1.76 0.12 84.84
101 INT335831 Positive_regulation of Gene_expression of LRRFIP1 1 0.15 0.91 0.19 84.72
102 INT88464 Negative_regulation of CST7 11 0.31 5.33 2.17 84.56
103 INT149384 Negative_regulation of TRPV4 4 0.43 2.41 1.23 84.20
104 INT311269 Positive_regulation of Positive_regulation of GCFC2 1 0.21 0.83 0.3 83.76
105 INT275871 Positive_regulation of CLPS 1 0.08 0.26 0.08 83.72
106 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 83.52
107 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67 83.28
108 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 83.28
109 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 82.68
110 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 82.60
111 INT112003 Localization of ROS1 94 0.73 66.32 12.16 82.60
112 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 81.68
113 INT192485 Negative_regulation of Binding of Rpusd1 1 0.01 0.4 0.05 81.20
114 INT192488 Binding of Rpusd1 1 0.00 0.4 0.05 80.68
115 INT49488 Gene_expression of mMCP-7 37 0.75 26.11 7.68 80.32
116 INT65713 Localization of ICAM1 42 0.81 39.55 11.49 79.84
117 INT32130 Gene_expression of TPSG1 12 0.51 6.59 1.88 79.52
118 INT153496 Negative_regulation of Pmp22 2 0.42 3.34 0.26 79.20
119 INT201259 Negative_regulation of RAB7A 2 0.41 2.45 0.54 78.84
120 INT194330 Regulation of Gene_expression of MFN2 1 0.45 0.3 0 78.04
121 INT194329 Positive_regulation of MFN2 1 0.40 0.74 0.03 77.60
122 INT91099 Gene_expression of MFN2 2 0.67 1.32 0.07 77.56
123 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 77.44
124 INT194331 Binding of MAD2L1BP 1 0.08 0.62 0.04 77.44
125 INT1764 Negative_regulation of Gene_expression of PTGER2 81 0.34 34.74 19.45 76.88
126 INT226176 Protein_catabolism of Hmbs 15 0.61 13.17 0.56 76.36
127 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 76.32
128 INT86370 Regulation of CDH1 10 0.54 13.89 0.7 76.16
129 INT184169 Positive_regulation of Gene_expression of FEZF2 2 0.17 2.8 0.26 75.84
130 INT120371 Gene_expression of FEZF2 12 0.66 4.97 1.38 75.84
131 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 75.76
132 INT196324 Localization of Cyp2b10 5 0.73 2.81 0.13 75.76
133 INT200185 Regulation of Igfals 10 0.26 11.4 1.47 75.44
134 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 75.40
135 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 75.32
136 INT188242 Negative_regulation of Positive_regulation of CRP 4 0.23 3.94 0.22 75.32
137 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 75.00
138 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 75.00
139 INT27822 Negative_regulation of HCFC1 1 0.58 0.48 0.13 75.00
140 INT139170 Negative_regulation of Gene_expression of Pmp22 1 0.37 0.83 0.09 75.00
141 INT139169 Gene_expression of Pmp22 10 0.68 8.37 2.5 75.00
142 INT61585 Gene_expression of NALCN 25 0.52 6.52 8.18 75.00
143 INT118232 Regulation of Gene_expression of NALCN 3 0.13 1.92 2.25 75.00
144 INT164512 Regulation of MPZ 12 0.30 8.38 1.53 75.00
145 INT164511 Negative_regulation of Binding of MPZ 2 0.36 1.64 0.29 75.00
146 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 74.96
147 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 74.72
148 INT190275 Positive_regulation of THAS 5 0.10 2.6 0.14 74.68
149 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 74.52
150 INT234814 Positive_regulation of AGFG1 6 0.10 2.33 0.07 74.52
151 INT96520 Gene_expression of PRPH 5 0.75 2.55 0.39 74.44
152 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 74.32
153 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47 74.32
154 INT144198 Positive_regulation of HSPB2 7 0.48 5.66 0.11 73.84
155 INT54615 Gene_expression of GPER 25 0.75 8.23 2.27 73.20
156 INT234828 Gene_expression of RAB3A 2 0.30 2.05 0.37 73.00
157 INT203372 Positive_regulation of Igfals 10 0.40 9.24 1.11 72.76
158 INT68565 Gene_expression of Fap 14 0.57 24.39 1.14 72.16
159 INT16178 Gene_expression of Clcn1 20 0.69 8.67 1.46 71.52
160 INT37012 Binding of Clcn1 11 0.33 4.83 0.7 71.52
161 INT12082 Localization of IL6 365 0.81 241.78 105.78 71.20
162 INT94163 Negative_regulation of UCN2 11 0.57 6.86 1.75 70.00
163 INT229794 Positive_regulation of RAB7A 2 0.65 11.68 1.31 69.28
164 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 68.24
165 INT153495 Binding of Pmp22 3 0.37 2.51 0.34 68.04
166 INT38672 Binding of KRT20 69 0.39 48.01 6.31 67.40
167 INT210272 Binding of Ccrs1 1 0.01 1.13 0 66.16
168 INT187055 Gene_expression of THAS 4 0.19 2.32 0.61 65.48
169 INT133174 Positive_regulation of Gene_expression of Il12b 29 0.15 13.04 2.92 64.12
170 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68 63.76
171 INT283536 Binding of Setx 1 0.36 3.69 0 63.44
172 INT56912 Gene_expression of Nefm 4 0.33 2.75 0.8 63.04
173 INT203353 Negative_regulation of Gene_expression of Nefm 1 0.12 0.84 0 63.04
174 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 62.84
175 INT298923 Positive_regulation of Protein_catabolism of NTRK1 1 0.13 0.5 0.07 62.72
176 INT48313 Binding of NTRK1 19 0.47 14.44 6.12 62.72
177 INT298887 Protein_catabolism of NTRK1 1 0.25 1.1 0.56 62.72
178 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 62.56
179 INT89543 Gene_expression of NEFL 18 0.75 10.6 2.67 62.56
180 INT298884 Binding of RAB7A 1 0.45 9.82 0.14 61.80
181 INT150276 Positive_regulation of LRRFIP1 2 0.37 1.34 0.03 61.76
182 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 60.24
183 INT39060 Gene_expression of Mpz 45 0.77 21.55 4.3 59.84
184 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 59.56
185 INT62336 Positive_regulation of Hdc 38 0.70 14.45 5.51 59.44
186 INT136187 Positive_regulation of Positive_regulation of Hdc 1 0.61 0.81 0.2 59.44
187 INT15610 Localization of GOPC 223 0.65 68.26 28.7 59.20
188 INT203361 Negative_regulation of Gene_expression of Tubb6 1 0.42 0.81 0 59.20
189 INT203351 Gene_expression of Tubb2a 2 0.69 2.01 0 59.20
190 INT203324 Gene_expression of Tubb6 1 0.55 0.81 0 59.20
191 INT203360 Negative_regulation of Gene_expression of Tubb2a 1 0.29 0.82 0 59.20
192 INT12339 Localization of IL8 437 0.81 251.87 117.39 58.80
193 INT230108 Localization of HIST4H4 2 0.40 1.07 0 58.72
194 INT335834 Gene_expression of LCP1 1 0.42 1.54 0.07 58.60
195 INT165402 Negative_regulation of THAS 2 0.42 0.72 0 57.68
196 INT100548 Regulation of SELP 8 0.29 8.56 1.17 56.96
197 INT267147 Regulation of Positive_regulation of SELP 2 0.29 3.94 0.42 56.96
198 INT60475 Gene_expression of Ugt1a1 17 0.77 4.26 5.62 56.88
199 INT104744 Negative_regulation of Gene_expression of Ugt1a1 2 0.53 0.85 0 56.88
200 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 56.80
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