D:Mrsa Infection

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Disease Term
Synonyms Antibacterial Resistance, Antimicrobial Resistance, Bacterial Resistance, Microbial Resistance, MRSA, Mrsa Infections, Multidrug Resistant Infection, Multidrug Resistant Infections, SEVERE HOSPITAL INFECTION, Severe Hospital Infections
Documents 432
Hot Single Events 51
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mrsa Infection. They are ordered first by their relevance to Mrsa Infection and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT306452 Binding of MBL2 and TLR4 1 0.38 0.37 0.1 60.68
2 INT306453 MBL2 Regulation of Binding of TLR4 1 0.48 0.37 0.1 60.68
3 INT353646 Binding of NPL and H58 1 0.01 0.26 0 60.04
4 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58 5.00
5 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47 5.00
6 INT43509 Avp Positive_regulation of Localization of POMC 2 0.13 1.26 1.16 5.00
7 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99 5.00
8 INT211105 Binding of CRS and IGHE 1 0.02 3.63 0.66 5.00
9 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46 5.00
10 INT175802 Il1 Positive_regulation of Gene_expression of Fos 1 0.00 0.66 0.44 5.00
11 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 5.00
12 INT329528 Seh1l Positive_regulation of Gene_expression of Csf2 1 0.07 0.37 0.28 5.00
13 INT329529 Tnfaip8 Positive_regulation of Gene_expression of Csf2 1 0.07 0.35 0.28 5.00
14 INT332481 ANXA1 Regulation of SGPP2 1 0.45 1.01 0.22 5.00
15 INT329530 Malt1 Positive_regulation of Positive_regulation of Nfkb1 1 0.06 0.48 0.22 5.00
16 INT332485 SGPP2 Regulation of ANXA1 1 0.27 0.69 0.13 5.00
17 INT332480 OR2A5 Regulation of SGPP2 1 0.00 0.32 0.1 5.00
18 INT332486 Binding of HSH2D and OR2A5 1 0.00 0.26 0.09 5.00
19 INT336030 PGE Regulation of Gene_expression of Cpox 1 0.05 0.22 0.07 5.00
20 INT336032 tf Positive_regulation of Gene_expression of Cpox 1 0.05 0.09 0.05 5.00
21 INT336031 tf Positive_regulation of Gene_expression of PGE 1 0.12 0.09 0.05 5.00
22 INT332488 OR2A5 Positive_regulation of HSH2D 1 0.00 0.19 0.05 5.00
23 INT332484 ANXA1 Positive_regulation of HSH2D 1 0.18 0.19 0.05 5.00
24 INT332489 Binding of JAM3 and SGPP2 1 0.27 0.24 0.04 5.00
25 INT332483 Binding of JAG1 and SGPP2 1 0.21 0.23 0.04 5.00
26 INT246640 GAST Positive_regulation of NFASC 1 0.00 1.26 0.03 5.00
27 INT325904 Binding of F2 and Wbp5 1 0.01 1.22 0 5.00
28 INT325898 Negative_regulation of Binding of F2 and Gopc 1 0.03 0.14 0 5.00
29 INT319483 Binding of LCT and HSR 1 0.11 0.23 0 5.00
30 INT325910 Wbp5 Positive_regulation of Positive_regulation of F2 1 0.01 0.67 0 5.00
31 INT325900 Binding of Dio1 and Wbp5 1 0.00 0.25 0 5.00
32 INT325902 Binding of F2 and Fgg 1 0.01 0 0 5.00
33 INT353647 Binding of CD82 and H58 1 0.05 0.86 0 5.00
34 INT270316 Binding of AMBP and NHS 1 0.20 0.91 0 5.00
35 INT325908 Binding of Wbp5 and Fgg 1 0.00 1.2 0 5.00
36 INT325903 Binding of F2 and Gopc 1 0.02 0.26 0 5.00
37 INT325901 Binding of Dio1 and F2 1 0.01 0.63 0 5.00
38 INT332487 ANXA1 Regulation of Gene_expression of SGPP2 1 0.45 0.08 0 5.00
39 INT325897 Negative_regulation of Binding of F2 and Wbp5 1 0.01 0.96 0 5.00
40 INT352482 Binding of PCA and Uncx 1 0.00 0.06 0 5.00
41 INT325905 Wbp5 Positive_regulation of F2 1 0.01 0.37 0 5.00
42 INT325906 Binding of Hps3 and Fgg 1 0.02 0.96 0 5.00
43 INT325899 Binding of Hps3 and F2 1 0.12 2.43 0 5.00
44 INT274437 Binding of IRF6 and LIPA 1 0.00 0.09 0 5.00
45 INT325907 Positive_regulation of Binding of F2 and Gopc 1 0.03 0.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mrsa Infection. They are ordered first by their pain relevance and then by number of times they were reported in Mrsa Infection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT217429 Positive_regulation of SLC9A6 22 0.38 42.17 0.67 100.00
2 INT209354 Gene_expression of SLC9A6 15 0.58 37.52 0.29 100.00
3 INT209355 Binding of SLC9A6 8 0.42 14.9 0.09 100.00
4 INT192975 Localization of SLC9A6 7 0.43 14.24 0.24 100.00
5 INT217431 Positive_regulation of Localization of SLC9A6 1 0.27 7.38 0.12 100.00
6 INT217428 Positive_regulation of Gene_expression of SLC9A6 3 0.29 4.99 0 100.00
7 INT209356 Regulation of SLC9A6 2 0.39 5.61 0.14 100.00
8 INT217427 Transcription of SLC9A6 1 0.38 4.64 0 100.00
9 INT217430 Negative_regulation of SLC9A6 1 0.32 2.44 0 100.00
10 INT217426 Positive_regulation of Binding of SLC9A6 1 0.27 2.04 0 100.00
11 INT217425 Regulation of Localization of SLC9A6 1 0.25 1.87 0.09 100.00
12 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45 100.00
13 INT44685 Gene_expression of Snd1 3 0.53 2.13 0.79 99.84
14 INT217424 Positive_regulation of Pou2f3 1 0.01 3.73 0 99.40
15 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45 99.38
16 INT323218 Gene_expression of ZC3H15 1 0.05 2.59 0.07 99.36
17 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 99.36
18 INT37392 Localization of BAS 4 0.61 0.96 2.49 97.88
19 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 97.52
20 INT101923 Binding of MICA 6 0.48 5.44 0.71 97.20
21 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59 96.88
22 INT325857 Localization of Hps3 1 0.78 9.66 0.03 96.28
23 INT325863 Localization of Wbp5 1 0.03 4.12 0.03 96.28
24 INT103716 Gene_expression of Cms1 14 0.65 8.52 1.3 96.16
25 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 95.44
26 INT135963 Negative_regulation of Hc 19 0.42 12.36 3.63 94.88
27 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 94.44
28 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 94.44
29 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 94.44
30 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.12
31 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 94.12
32 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 94.12
33 INT297935 Positive_regulation of SUMF2 1 0.02 0.95 0 93.88
34 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 93.80
35 INT110210 Negative_regulation of CSRP1 12 0.59 8.96 2.81 93.44
36 INT90826 Localization of NFASC 8 0.17 6.01 1.97 91.56
37 INT323220 Transcription of ZC3H15 1 0.04 0.95 0 90.48
38 INT9732 Regulation of COL2A1 9 0.58 6.93 0.44 90.12
39 INT276437 Binding of Spir1 4 0.12 6.56 0 89.48
40 INT1148 Positive_regulation of ecs 38 0.48 25.27 13.1 89.36
41 INT247102 Binding of MBL2 16 0.38 14.18 1.54 88.88
42 INT279580 Positive_regulation of Binding of MBL2 4 0.48 2.15 0.08 88.88
43 INT109405 Binding of MASP1 2 0.07 0.49 0.21 88.72
44 INT306470 Positive_regulation of Binding of MASP1 1 0.09 0.49 0.06 88.72
45 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 88.40
46 INT31991 Gene_expression of NTS 33 0.75 12.98 4.99 86.24
47 INT282226 Negative_regulation of Ptpro 1 0.03 1.02 0 84.48
48 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 84.00
49 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47 83.56
50 INT36301 Negative_regulation of TOP2A 3 0.57 2.66 0 83.48
51 INT160095 Binding of DDX20 1 0.14 0.34 0 83.36
52 INT35242 Negative_regulation of MBL2 17 0.48 12.53 1.73 78.88
53 INT323219 Positive_regulation of ZC3H15 1 0.04 1.09 0.04 78.36
54 INT120466 Gene_expression of LCT 21 0.78 6 1.75 76.48
55 INT323215 Regulation of Binding of ZC3H15 1 0.03 0.99 0 76.16
56 INT63839 Binding of CRS 31 0.41 34.05 4.7 76.16
57 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89 75.72
58 INT56248 Positive_regulation of Nbas 2 0.23 0.65 0.09 75.72
59 INT75822 Gene_expression of TRA@ 2 0.65 0.34 0.24 75.68
60 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 75.56
61 INT308260 Positive_regulation of TOP2A 1 0.03 0.58 0 75.36
62 INT118827 Regulation of TOP2A 4 0.04 1.75 0 75.36
63 INT323217 Binding of ZC3H15 1 0.03 0.98 0 75.16
64 INT121683 Gene_expression of Hc 23 0.75 7.15 2.7 74.68
65 INT325862 Negative_regulation of Wbp5 1 0.02 1.43 0 72.76
66 INT90820 Gene_expression of MICA 11 0.24 7.64 0.06 72.40
67 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 69.76
68 INT325867 Gene_expression of Wbp5 1 0.03 2.15 0 66.32
69 INT152616 Gene_expression of SPECC1 8 0.66 8.43 4.32 63.68
70 INT243268 Gene_expression of SLC40A1 6 0.60 4.18 0.13 61.12
71 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 59.92
72 INT53572 Negative_regulation of Localization of Il1 18 0.40 12.78 6.7 59.92
73 INT6852 Localization of TNF 883 0.81 705.95 270.84 59.32
74 INT19775 Localization of Il1 183 0.78 145.5 50.91 59.32
75 INT37390 Regulation of Crp 39 0.46 28.74 11.45 59.28
76 INT134651 Binding of TLR4 89 0.48 66.96 23.19 59.24
77 INT325859 Positive_regulation of Localization of Hps3 1 0.45 1.13 0 59.12
78 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 57.40
79 INT353640 Localization of H50 1 0.04 1.07 0.15 56.96
80 INT353638 Localization of H52 1 0.05 1.08 0.15 56.96
81 INT325853 Binding of Wbp5 1 0.02 1.07 0 56.08
82 INT314906 Gene_expression of REG4 1 0.05 0.51 0.04 55.16
83 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 54.60
84 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 54.60
85 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 53.36
86 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 52.52
87 INT21406 Negative_regulation of Gene_expression of IgG 20 0.41 9.36 3.58 51.36
88 INT279572 Gene_expression of MBL2 27 0.64 20.88 1.51 51.12
89 INT306468 Positive_regulation of Gene_expression of MBL2 7 0.47 4.3 0.17 51.12
90 INT213409 Gene_expression of TK2 1 0.25 2.95 0.5 50.76
91 INT213411 Positive_regulation of TK2 1 0.21 2.95 0.5 50.32
92 INT346929 Negative_regulation of Anth 1 0.01 0.23 0 50.08
93 INT159223 Binding of NR4A2 2 0.47 0.38 0.12 49.52
94 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 48.12
95 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 46.12
96 INT101549 Negative_regulation of EMP1 8 0.57 1.82 1.01 46.00
97 INT144639 Regulation of TPCN1 2 0.32 1.08 0 45.80
98 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 43.24
99 INT179548 Gene_expression of C4b 17 0.58 9.88 1.62 41.96
100 INT184341 Negative_regulation of C4b 12 0.50 7.66 0.75 41.96
101 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 41.84
102 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 41.44
103 INT151978 Negative_regulation of Positive_regulation of Cys1 3 0.41 4.15 0.24 41.44
104 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 40.64
105 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 40.64
106 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 39.28
107 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 39.28
108 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84 39.04
109 INT14450 Binding of NEU1 7 0.14 5.1 0.5 38.24
110 INT323216 Localization of ZC3H15 1 0.06 0.1 0 38.08
111 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 37.84
112 INT16214 Localization of F13A1 36 0.74 21.8 4.87 37.36
113 INT74879 Regulation of MPG 6 0.44 0.8 1.08 36.64
114 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 36.12
115 INT353639 Gene_expression of H58 1 0.08 1.37 0.06 35.92
116 INT241554 Binding of Htra3 1 0.04 0.6 0 35.16
117 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 31.40
118 INT323214 Regulation of ZC3H15 1 0.02 0.29 0 31.32
119 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 31.20
120 INT59010 Positive_regulation of Regulation of Crp 2 0.27 2.11 1.09 30.32
121 INT16178 Gene_expression of Clcn1 20 0.69 8.67 1.46 28.16
122 INT76278 Binding of VAPA 4 0.48 3.32 0.16 27.64
123 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 27.00
124 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65 27.00
125 INT94464 Negative_regulation of Hand1 44 0.41 31.5 12.39 24.72
126 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 23.92
127 INT226991 Gene_expression of TPCN1 4 0.09 0.8 0 22.72
128 INT270364 Gene_expression of TOP1MT 1 0.65 0.43 0.03 20.00
129 INT279576 Positive_regulation of MBL2 4 0.38 4.1 0 17.52
130 INT195869 Positive_regulation of MASP1 3 0.08 1.58 0.03 16.88
131 INT1898 Regulation of Crh 220 0.62 61.33 102.64 16.48
132 INT9429 Positive_regulation of Clcn1 18 0.58 10.03 2.07 15.68
133 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3 15.24
134 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 14.68
135 INT30209 Localization of SCN5A 24 0.72 7.95 5.35 12.80
136 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 11.28
137 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 11.12
138 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 10.72
139 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99 10.28
140 INT206796 Positive_regulation of VAMP7 2 0.56 4.12 0.07 9.92
141 INT271150 Positive_regulation of CMM 1 0.13 0 0 8.60
142 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29 8.28
143 INT2774 Binding of Crp 241 0.48 195.89 44.39 8.24
144 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 7.56
145 INT271152 Positive_regulation of NUDT1 4 0.17 1.34 0 7.56
146 INT1562 Localization of Crh 499 0.81 126.74 236.68 7.08
147 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12 6.40
148 INT2064 Positive_regulation of BTG3 29 0.49 25.58 15.37 5.20
149 INT184068 Positive_regulation of Socs1 7 0.51 4.03 1.73 5.04
150 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 5.00
151 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
152 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
153 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 5.00
154 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
155 INT876 Localization of Gh1 843 0.80 67.75 340.82 5.00
156 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
157 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
158 INT477 Localization of Avp 813 0.81 131.58 300.4 5.00
159 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 5.00
160 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
161 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
162 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
163 INT738 Regulation of POMC 459 0.62 111.19 243.74 5.00
164 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
165 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
166 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 5.00
167 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
168 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 5.00
169 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
170 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
171 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
172 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 5.00
173 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 5.00
174 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 5.00
175 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
176 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
177 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
178 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 5.00
179 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
180 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
181 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
182 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 5.00
183 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 5.00
184 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 5.00
185 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58 5.00
186 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
187 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
188 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
189 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
190 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
191 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
192 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
193 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
194 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
195 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
196 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 5.00
197 INT1782 Regulation of Gh1 125 0.62 22 55.74 5.00
198 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 5.00
199 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92 5.00
200 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 5.00
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