D:Mucinous Adenocarcinoma

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Disease Term
Synonyms Adenocarcinomas Mucinous, Carcinoma Colloid, Carcinoma Mucinous, Carcinomas Colloid, Carcinomas Mucinous, COLLOID CARCINOMA, Colloid Carcinomas, MUCINOUS ADENOCARCINOMAS, Mucinous Carcinoma, Mucinous Carcinomas
Documents 146
Hot Single Events 34
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mucinous Adenocarcinoma. They are ordered first by their relevance to Mucinous Adenocarcinoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT219875 Binding of KRT7 and Krt20 1 0.01 1.32 0.04 29.68
2 INT219857 Binding of Krt20 and Nbr1 1 0.00 1.31 0.04 29.68
3 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 28.08
4 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 27.68
5 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
6 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
7 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22 5.00
8 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2 5.00
9 INT291346 IL8 Positive_regulation of Binding of EGFR and GRB2 1 0.15 1.17 0.2 5.00
10 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16 5.00
11 INT291347 Positive_regulation of TXK Positive_regulation of CXCR4 Positive_regulation of EPHB2 1 0.02 0.61 0.13 5.00
12 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13 5.00
13 INT291353 IL8 Positive_regulation of Binding of EGFR 1 0.32 0.52 0.1 5.00
14 INT191184 Binding of EGFR and GRB2 7 0.35 1.06 0.1 5.00
15 INT291351 Binding of EGFR and SHC1 1 0.05 0.57 0.1 5.00
16 INT291350 IL8 Positive_regulation of Phosphorylation of EGFR 1 0.32 0.52 0.1 5.00
17 INT291358 Binding of CXCL12 and CXCR7 1 0.20 0.11 0.09 5.00
18 INT291355 CXCL12 Positive_regulation of Gene_expression of HGF 1 0.06 1.53 0.06 5.00
19 INT291356 CXCL12 Positive_regulation of AKT1 1 0.04 1.28 0.03 5.00
20 INT291357 CXCR4 Positive_regulation of AKT1 1 0.08 1.27 0.03 5.00
21 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0 5.00
22 INT304020 AR Regulation of TP53 1 0.24 1.11 0 5.00
23 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0 5.00
24 INT245158 AD5 Regulation of PKD1 1 0.00 0.44 0 5.00
25 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0 5.00
26 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0 5.00
27 INT206824 Binding of Muc5b and Gopc 1 0.07 0.05 0 5.00
28 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0 5.00
29 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 5.00
30 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0 5.00
31 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0 5.00
32 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0 5.00
33 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0 5.00
34 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0 5.00
35 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0 5.00
36 INT206825 Binding of Muc2 and Gopc 1 0.08 0.05 0 5.00
37 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0 5.00
38 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0 5.00
39 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 5.00
40 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0 5.00
41 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0 5.00
42 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0 5.00
43 INT304016 SFRP4 Regulation of Binding of MSI1 1 0.04 1.78 0 5.00
44 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 5.00
45 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mucinous Adenocarcinoma. They are ordered first by their pain relevance and then by number of times they were reported in Mucinous Adenocarcinoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 99.98
2 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 99.98
3 INT86889 Gene_expression of Cdx2 8 0.60 4.23 1.02 99.98
4 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 99.98
5 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55 99.84
6 INT73627 Binding of Fap 8 0.36 11.14 0.4 99.20
7 INT21841 Positive_regulation of PPPD1 4 0.38 3.46 0.16 98.92
8 INT88744 Positive_regulation of Gene_expression of MDM2 9 0.43 7.82 0.2 96.88
9 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 96.88
10 INT37809 Gene_expression of SERPINB6 7 0.77 6.58 2.12 95.44
11 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 95.08
12 INT206819 Gene_expression of Muc6 7 0.61 4.22 0.19 94.44
13 INT341437 Gene_expression of Slc25a16 1 0.47 2.39 0.3 91.80
14 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84 91.60
15 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 91.36
16 INT97174 Positive_regulation of SERPINB6 5 0.50 3.74 0.91 91.04
17 INT18898 Positive_regulation of CHGA 38 0.67 28.99 4.86 90.76
18 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 86.56
19 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 86.36
20 INT22429 Positive_regulation of PDAP1 34 0.61 22.58 2.91 86.36
21 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78 85.84
22 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 85.64
23 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 85.44
24 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68 85.20
25 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 84.56
26 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 84.20
27 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 83.92
28 INT103683 Gene_expression of Muc2 18 0.73 12.47 2.43 83.92
29 INT67191 Gene_expression of Muc3 11 0.29 9.93 0.91 83.92
30 INT164210 Gene_expression of Cdx2 3 0.56 2.22 0.25 83.92
31 INT215181 Binding of Muc2 1 0.17 0.77 0 82.96
32 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 82.32
33 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 81.16
34 INT215183 Positive_regulation of MUC5AC 4 0.45 2.78 0.6 80.88
35 INT237245 Positive_regulation of Gene_expression of Fus 1 0.38 4.8 1.55 77.56
36 INT237251 Positive_regulation of Gene_expression of Mri1 1 0.30 1.13 0.63 77.56
37 INT86370 Regulation of CDH1 10 0.54 13.89 0.7 77.44
38 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 77.04
39 INT173967 Gene_expression of Mri1 26 0.43 16.67 6.45 77.00
40 INT231240 Gene_expression of Fus 2 0.56 20.05 3.9 76.56
41 INT176154 Gene_expression of PIK3CA 6 0.55 10.43 0.03 76.48
42 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 76.28
43 INT206820 Gene_expression of Muc1 17 0.60 13.48 0.36 76.24
44 INT156293 Localization of Fus 3 0.64 6.95 1.75 76.16
45 INT237253 Regulation of Localization of Fus 1 0.34 1.41 0.43 76.16
46 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97 75.96
47 INT237252 Localization of Mri1 7 0.45 4.42 2.23 75.84
48 INT237243 Regulation of Localization of Mri1 1 0.27 1.41 0.43 75.84
49 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 75.60
50 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 75.60
51 INT67190 Gene_expression of Muc2 24 0.78 18.8 2.08 71.92
52 INT2139 Negative_regulation of Cea 55 0.43 43.59 9.14 69.64
53 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 69.28
54 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 68.60
55 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 68.60
56 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 68.60
57 INT39000 Regulation of pr 24 0.44 12.51 4.36 68.32
58 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 68.24
59 INT81396 Regulation of Gene_expression of ERBB2 14 0.43 10.73 0.74 68.24
60 INT128916 Regulation of CES1 5 0.40 2.95 0.29 62.64
61 INT11154 Binding of EGFR 149 0.48 96.23 6.29 61.44
62 INT52962 Binding of ERBB2 77 0.47 50.03 1.49 61.44
63 INT82795 Binding of MYC 16 0.47 6.1 0.9 61.44
64 INT98708 Binding of KRAS 13 0.47 7.47 0.39 61.44
65 INT179260 Binding of AKT2 2 0.27 1.8 0.15 61.44
66 INT260288 Binding of FGF1 3 0.32 2.46 0 61.44
67 INT286095 Gene_expression of Afap1 1 0.09 2.42 0.03 60.80
68 INT6476 Gene_expression of TNFRSF1B 21 0.67 18.22 5.25 59.52
69 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 59.36
70 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97 59.36
71 INT38672 Binding of KRT20 69 0.39 48.01 6.31 59.32
72 INT198405 Binding of CDX2 1 0.32 1.01 0 58.96
73 INT49802 Localization of MUC1 75 0.81 44.74 8.87 57.32
74 INT291365 Positive_regulation of Gene_expression of PIK3CA 2 0.41 5.76 0 55.36
75 INT76884 Positive_regulation of Cp 22 0.69 12.84 4.6 52.76
76 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 50.00
77 INT152552 Gene_expression of Muc5ac 24 0.73 19.44 4 47.04
78 INT124315 Negative_regulation of IGF2BP3 1 0.11 1.48 0.26 46.40
79 INT78281 Gene_expression of Krt7 28 0.70 26.77 0.97 45.60
80 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 45.32
81 INT38266 Localization of PTPRC 30 0.68 17.05 1.68 44.08
82 INT206822 Localization of Muc2 11 0.70 5.59 0.58 44.08
83 INT260162 Gene_expression of PPPD1 4 0.55 4.26 0.04 43.68
84 INT91754 Gene_expression of Cp 42 0.77 21.97 5.38 43.48
85 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14 43.12
86 INT130889 Regulation of KRT7 4 0.07 3.74 0.39 43.12
87 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74 42.72
88 INT183094 Gene_expression of Panc1 14 0.09 15.09 0.25 42.72
89 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 42.32
90 INT37005 Regulation of Nbr1 6 0.24 6.33 1.56 42.32
91 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25 41.28
92 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36 40.48
93 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 39.44
94 INT265588 Localization of Fap 4 0.47 5.67 0 39.04
95 INT92139 Binding of MLH1 12 0.42 15.62 1 38.84
96 INT84894 Gene_expression of Calb2 45 0.73 24.65 7.81 37.20
97 INT124314 Gene_expression of IGF2BP3 7 0.77 33.13 0.97 35.84
98 INT124313 Positive_regulation of Gene_expression of IGF2BP3 4 0.69 8.07 0.45 35.84
99 INT70445 Binding of KRT1 10 0.35 5.38 0.47 35.16
100 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 34.60
101 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 34.24
102 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 34.24
103 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86 34.24
104 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63 34.24
105 INT201858 Gene_expression of SFRP4 3 0.48 4.91 0.51 34.24
106 INT206869 Gene_expression of ALDH1A2 3 0.38 2.51 0.16 34.24
107 INT304053 Gene_expression of KIAA1324 1 0.18 0.98 0 34.24
108 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 33.32
109 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22 33.32
110 INT201846 Positive_regulation of SFRP4 4 0.37 2.74 0.54 33.32
111 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05 33.32
112 INT304063 Positive_regulation of ALDH1A2 1 0.29 0.97 0 33.32
113 INT304064 Positive_regulation of KIAA1324 1 0.14 0.98 0 33.32
114 INT206823 Localization of Muc5b 5 0.78 5.15 0.43 31.32
115 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 30.24
116 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67 28.72
117 INT52943 Positive_regulation of Positive_regulation of Afp 1 0.31 1.11 0.17 28.72
118 INT745 Gene_expression of Afp 65 0.78 52.89 4.24 28.32
119 INT15046 Positive_regulation of Gene_expression of Afp 6 0.46 5.95 0.52 28.32
120 INT55688 Gene_expression of MMP11 15 0.74 10.95 1.06 27.60
121 INT126805 Gene_expression of APOD 2 0.74 1.24 0.42 26.80
122 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 26.60
123 INT97446 Localization of Mki67 9 0.46 3.74 0.46 26.48
124 INT126804 Gene_expression of APOC1 1 0.75 1.06 0.14 26.32
125 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 25.76
126 INT186998 Negative_regulation of Gene_expression of KIT 20 0.43 16.77 0.46 25.32
127 INT124312 Negative_regulation of Gene_expression of IGF2BP3 1 0.12 0.83 0.09 25.00
128 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 24.96
129 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 24.96
130 INT122813 Binding of Krt20 11 0.32 13.77 0.88 22.08
131 INT22455 Binding of Nbr1 8 0.21 10.57 0.93 21.60
132 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 17.80
133 INT245173 Gene_expression of MDK 81 0.49 51.08 6.78 16.48
134 INT131931 Binding of KRT7 13 0.36 19.24 0.5 13.20
135 INT105782 Positive_regulation of Krt20 9 0.20 9.62 0.53 10.72
136 INT185087 Positive_regulation of Muc2 1 0.09 2.47 0.15 10.28
137 INT185088 Positive_regulation of Positive_regulation of Muc2 1 0.08 1.24 0.08 7.88
138 INT132213 Positive_regulation of Gene_expression of Muc2 3 0.69 1.57 0.07 7.88
139 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
140 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
141 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
142 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
143 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96 5.00
144 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
145 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
146 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
147 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
148 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 5.00
149 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 5.00
150 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 5.00
151 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 5.00
152 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
153 INT121663 Gene_expression of CXCR3 76 0.77 50.96 30.62 5.00
154 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
155 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
156 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
157 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 5.00
158 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 5.00
159 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
160 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 5.00
161 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
162 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
163 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
164 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 5.00
165 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 5.00
166 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 5.00
167 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
168 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
169 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
170 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
171 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 5.00
172 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 5.00
173 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
174 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 5.00
175 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 5.00
176 INT137181 Gene_expression of CXCL9 25 0.65 13.09 9.56 5.00
177 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
178 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 5.00
179 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25 5.00
180 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25 5.00
181 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21 5.00
182 INT39170 Gene_expression of TSPO 76 0.78 24.11 8.05 5.00
183 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
184 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79 5.00
185 INT78320 Gene_expression of EPCAM 57 0.75 50.34 7.53 5.00
186 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
187 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48 5.00
188 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 5.00
189 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84 5.00
190 INT117186 Positive_regulation of CXCR4 29 0.69 24.19 6.84 5.00
191 INT211701 Positive_regulation of Mri1 20 0.34 20.64 6.69 5.00
192 INT2137 Localization of Cea 27 0.70 19.22 6.14 5.00
193 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 5.00
194 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 5.00
195 INT113112 Negative_regulation of CXCR4 39 0.58 28.28 5.36 5.00
196 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 5.00
197 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
198 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
199 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 5.00
200 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67 5.00
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