D:Mucopolysaccharidosis Ii

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pChart

Disease Term
Synonyms Gargoylism Hunter Syndrome, Gargoylisms Hunter Syndrome, Hunter S Syndrome, HUNTER SYNDROME, Hunter Syndrome Gargoylism, Hunter Syndrome Gargoylisms, Hunters Syndrome, IIS MUCOPOLYSACCHARIDOSIS, Mucopolysaccharidosis 2, Mucopolysaccharidosis Iis, Syndrome Hunter S
Documents 19
Hot Single Events 10
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Mucopolysaccharidosis Ii. They are ordered first by their relevance to Mucopolysaccharidosis Ii and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 50.00
2 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 50.00
3 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09 25.08
4 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09 25.08
5 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
6 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00
7 INT277891 Binding of TPBG and M6pr-ps 1 0.02 0.06 0 5.00
8 INT277892 IDS Regulation of Ids 1 0.18 0.41 0 5.00
9 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Mucopolysaccharidosis Ii. They are ordered first by their pain relevance and then by number of times they were reported in Mucopolysaccharidosis Ii. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT192194 Positive_regulation of FBXW11 3 0.34 0.84 0.14 99.96
2 INT277880 Gene_expression of Tas2r111-ps2 1 0.13 1.22 0 99.92
3 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 99.84
4 INT277882 Gene_expression of Ids 5 0.71 1.6 0.26 99.80
5 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 99.66
6 INT223092 Negative_regulation of AP2S1 1 0.01 0.72 0 98.82
7 INT153233 Negative_regulation of Ids 5 0.40 2.1 0.12 97.78
8 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41 96.36
9 INT223093 Phosphorylation of NAGLU 1 0.45 0.95 0 91.88
10 INT86569 Gene_expression of AP2S1 2 0.15 0.55 0 89.44
11 INT105992 Positive_regulation of Gene_expression of IDS 4 0.69 0.84 0.35 79.88
12 INT151400 Binding of JAG1 14 0.37 7.96 0.39 75.00
13 INT1755 Gene_expression of GBE1 28 0.26 8.32 5.18 73.72
14 INT10585 Localization of NAGLU 53 0.80 23.32 12.75 60.80
15 INT277886 Localization of Ids 3 0.73 1.09 0.48 60.60
16 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29 58.40
17 INT3163 Gene_expression of NAGLU 28 0.75 15.23 4.98 50.00
18 INT150476 Positive_regulation of ELF3 32 0.56 13.61 2.39 50.00
19 INT68829 Binding of ELF3 14 0.47 7.96 2 50.00
20 INT194074 Regulation of NAGLU 5 0.38 2.93 1.87 50.00
21 INT223091 Gene_expression of ELF3 45 0.62 17.9 1.56 50.00
22 INT200462 Binding of IDS 13 0.31 4.95 1 50.00
23 INT277878 Binding of Ids 4 0.34 0.8 0.24 25.56
24 INT217723 Regulation of IDS 15 0.25 2.12 0.49 24.16
25 INT277884 Binding of Tas2r111-ps2 1 0.09 0.95 0.19 8.96
26 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
27 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23 5.00
28 INT14306 Positive_regulation of Gal 36 0.70 21.66 18.51 5.00
29 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
30 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
31 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14 5.00
32 INT51165 Binding of Gal 10 0.48 2.56 8.41 5.00
33 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 5.00
34 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 5.00
35 INT102547 Gene_expression of Cd68 25 0.75 14.47 5.22 5.00
36 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 5.00
37 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 5.00
38 INT5219 Negative_regulation of DBP 43 0.57 23.35 4.26 5.00
39 INT183207 Negative_regulation of USE1 14 0.18 10.97 4 5.00
40 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 5.00
41 INT142724 Negative_regulation of A4GALT 11 0.53 8.23 2.61 5.00
42 INT65545 Localization of EGFR 35 0.79 20.8 1.88 5.00
43 INT167153 Gene_expression of A4GALT 10 0.49 10.45 1.71 5.00
44 INT121513 Positive_regulation of A4GALT 21 0.63 16.06 1.59 5.00
45 INT36179 Regulation of GLA 11 0.44 6.56 1.12 5.00
46 INT352186 Negative_regulation of Gene_expression of A4GALT 1 0.20 2.56 1.06 5.00
47 INT188774 Binding of RAPGEF5 12 0.29 13.55 1.04 5.00
48 INT4681 Localization of RAPGEF5 12 0.68 8.69 0.93 5.00
49 INT47553 Gene_expression of ARSH 11 0.42 4.93 0.65 5.00
50 INT164258 Positive_regulation of Gene_expression of GLA 6 0.47 0.55 0.65 5.00
51 INT137221 Gene_expression of Sh2d1b2 6 0.47 1.99 0.6 5.00
52 INT137222 Positive_regulation of Sh2d1b2 5 0.30 1.26 0.6 5.00
53 INT121514 Localization of A4GALT 7 0.25 4.77 0.58 5.00
54 INT16671 Gene_expression of MBTPS1 7 0.30 4.8 0.52 5.00
55 INT171606 Regulation of Localization of Sh2d1b2 2 0.13 0.41 0.42 5.00
56 INT171608 Localization of Sh2d1b2 2 0.21 0.4 0.42 5.00
57 INT263255 Negative_regulation of Negative_regulation of AGTR1 2 0.30 2.88 0.25 5.00
58 INT345358 Positive_regulation of Localization of Sh2d1b2 1 0.14 0.11 0.24 5.00
59 INT345359 Positive_regulation of Ids 1 0.50 0.27 0.24 5.00
60 INT222082 Localization of Lamp2 3 0.49 0.19 0.19 5.00
61 INT345356 Localization of Tiaf2 1 0.02 0.19 0.19 5.00
62 INT244330 Localization of ELF3 8 0.56 2.71 0.18 5.00
63 INT310677 Localization of ARSB 1 0.71 5.72 0.14 5.00
64 INT352180 Negative_regulation of Gene_expression of GLA 1 0.42 1.06 0.13 5.00
65 INT310680 Gene_expression of ARSB 1 0.64 6.28 0.12 5.00
66 INT277879 Positive_regulation of Gene_expression of Ids 3 0.44 0.14 0.11 5.00
67 INT345357 Protein_catabolism of Ids 1 0.57 0.2 0.09 5.00
68 INT245115 Positive_regulation of Gene_expression of ELF3 8 0.40 2.23 0.06 5.00
69 INT345361 Positive_regulation of Positive_regulation of Ids 1 0.44 0.41 0.06 5.00
70 INT234263 Negative_regulation of ELF3 6 0.39 3.9 0.04 5.00
71 INT310678 Protein_catabolism of ARSH 1 0.06 1.76 0.04 5.00
72 INT310679 Positive_regulation of ARSB 1 0.39 2.36 0.04 5.00
73 INT310682 Regulation of ARSB 1 0.43 0.98 0.04 5.00
74 INT310683 Protein_catabolism of ARSB 1 0.73 1.85 0.04 5.00
75 INT352176 Localization of Cst3 1 0.78 1.71 0.04 5.00
76 INT277877 Binding of M6pr-ps 1 0.02 0.06 0 5.00
77 INT277881 Negative_regulation of Tas2r111-ps2 1 0.07 0.15 0 5.00
78 INT277883 Regulation of Tas2r111-ps2 1 0.05 0.15 0 5.00
79 INT277888 Binding of TPBG 1 0.35 0.06 0 5.00
80 INT345360 Regulation of Gene_expression of Ids 1 0.39 0 0 5.00
81 INT352181 Regulation of NAGA 1 0.11 0.34 0 5.00
82 INT352182 Regulation of A4GALT 1 0.15 0.18 0 5.00
83 INT352183 Positive_regulation of Gene_expression of A4GALT 1 0.23 0.84 0 5.00
84 INT352185 Negative_regulation of PCDH11X 1 0.01 0.83 0 5.00
85 INT352187 Phosphorylation of A4GALT 1 0.27 0.13 0 5.00
86 INT352188 Negative_regulation of Localization of A4GALT 1 0.17 0 0 5.00
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