D:Multiple Myeloma

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Disease Term
Synonyms Disorder Subdivisions, Extramedullary Plasmacytoma, KAHLER DISEASE, Multiple Myelomas, Myeloma Multiple, Myeloma Plasma Cell, MYELOMAS MULTIPLE, Myelomas Plasma Cell, Myelomatosis, NONSECRETORY MYELOMA, Osteosclerotic Myeloma
Documents 1166
Hot Single Events 200
Hot Interactions 41

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Multiple Myeloma. They are ordered first by their relevance to Multiple Myeloma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT49283 Binding of IGLL1 and IFNK 1 0.02 0.9 0.1 100.00
2 INT298632 STAT3 Positive_regulation of MIR21 1 0.03 0.84 0 99.68
3 INT139784 PRSS53 Negative_regulation of Positive_regulation of NFKB1 1 0.09 0.9 0.11 99.60
4 INT139785 TNFAIP8 Positive_regulation of Positive_regulation of NFKB1 1 0.19 0.89 0.11 99.60
5 INT341666 ALPI Positive_regulation of ENPEP 1 0.01 1.05 0 99.08
6 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 98.96
7 INT298640 IL6R Positive_regulation of STAT3 1 0.01 0.73 0.03 98.76
8 INT236235 HLA-A Positive_regulation of CD8A 1 0.01 1 0.03 98.52
9 INT139792 TNFAIP8 Positive_regulation of Protein_catabolism of IKBKG 1 0.12 0.89 0.11 98.16
10 INT139790 PRSS53 Negative_regulation of Phosphorylation of NFKBIA 1 0.01 0.9 0.11 97.52
11 INT139786 TNFAIP8 Positive_regulation of Phosphorylation of IKBKG 1 0.12 0.89 0.11 97.52
12 INT139789 TNFAIP8 Positive_regulation of Phosphorylation of NFKBIA 1 0.02 0.89 0.11 97.52
13 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08 97.32
14 INT139788 TNFAIP8 Positive_regulation of NFKBIA 1 0.01 0.88 0.11 96.88
15 INT139791 PRSS53 Negative_regulation of NFKB1 1 0.09 0.71 0.13 96.84
16 INT144034 STAT6 Positive_regulation of STAT3 1 0.04 0.1 0 96.52
17 INT287480 Protein_catabolism of NFKBIB Positive_regulation of TBK1 1 0.01 0.6 0.03 96.40
18 INT139787 Negative_regulation of TNFAIP8 Positive_regulation of IKBKG 1 0.10 0.89 0.11 96.16
19 INT139783 TNFAIP8 Positive_regulation of IKBKG 1 0.12 0.88 0.11 96.16
20 INT287479 PSMB10 Positive_regulation of TBK1 1 0.00 0.59 0.03 95.52
21 INT139782 PRSS53 Negative_regulation of Positive_regulation of ASNA1 1 0.01 0.91 0.11 94.88
22 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0 92.08
23 INT298633 STAT3 Regulation of MCL1 1 0.04 0.85 0.03 92.08
24 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61 90.52
25 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61 90.52
26 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61 90.52
27 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61 90.52
28 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61 90.52
29 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31 90.52
30 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31 90.52
31 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31 90.52
32 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31 90.52
33 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 88.92
34 INT198006 ERI3 Negative_regulation of MCL1 1 0.01 1.63 0 88.08
35 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 84.52
36 INT148531 Binding of TNFRSF11A and Tnfsf11 2 0.08 1.77 0.17 82.68
37 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 82.52
38 INT295006 Binding of TNFRSF11A and Tnfrsf11b 2 0.10 1.6 0.04 82.52
39 INT295003 Binding of Tnfrsf11b and Tnfsf11 3 0.22 1.85 0.08 82.32
40 INT148532 Binding of CCL3 and Tnfsf11 1 0.03 0.71 0.14 81.52
41 INT234381 Binding of CD40 and PPARA 1 0.19 1.39 0.07 80.72
42 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15 79.68
43 INT144033 STAT6 Positive_regulation of Positive_regulation of STAT3 1 0.04 0.08 0 79.04
44 INT298683 ecs Positive_regulation of Gene_expression of VEGFA 1 0.02 1.41 0.04 78.04
45 INT140289 ROS1 Positive_regulation of MAPK14 1 0.44 1.27 0.06 77.32
46 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06 77.32
47 INT103207 Binding of TNFSF14 and IgG 1 0.06 0.31 0.09 75.00
48 INT198005 Binding of BID and MCL1 1 0.24 2.04 0 73.52
49 INT128221 Binding of IL6ST and Il6 2 0.00 0.73 0.17 71.52
50 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 71.36
51 INT210592 Binding of Cd4 and Vcam1 1 0.01 0.65 0.03 70.84
52 INT198022 AKT1 Regulation of Gene_expression of MCL1 1 0.15 2.25 0 69.44
53 INT198020 PIK3CA Regulation of Gene_expression of MCL1 1 0.16 2.25 0 69.44
54 INT305632 Binding of BCL6 and MME 1 0.00 1.37 0 68.08
55 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05 68.00
56 INT234380 Negative_regulation of Binding of CD40 and CD40LG 1 0.16 1.4 0.04 67.12
57 INT197999 Binding of BCL2 and MCL1 Negative_regulation of C12orf65 1 0.00 1.21 0 64.96
58 INT198021 Binding of BCL2 and MCL1 1 0.17 2.88 0 64.96
59 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 64.32
60 INT290673 Ppara Positive_regulation of Gtf3a 1 0.01 0.58 0.09 64.16
61 INT290674 Ppara Positive_regulation of Gtf3a Positive_regulation of Ppara 1 0.01 0.58 0.09 64.16
62 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 64.00
63 INT276300 TAT Regulation of Gene_expression of VEGFA 1 0.14 1.58 0 63.84
64 INT198015 Binding of BAK1 and MCL1 1 0.26 5.16 0 63.28
65 INT219150 Binding of CXCL11 and CXCR7 1 0.09 1.77 0.09 63.20
66 INT144030 STAT3 Regulation of CCND1 2 0.09 1.05 0 62.52
67 INT144031 STAT3 Regulation of BCL2L1 1 0.11 0.06 0 62.52
68 INT144042 STAT3 Regulation of Birc5 1 0.47 0.06 0 62.52
69 INT144029 STAT3 Regulation of FIGF 1 0.12 0.06 0 62.52
70 INT171976 Il18 Positive_regulation of Gene_expression of IFNA1 1 0.01 1.37 0.64 62.20
71 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05 61.88
72 INT235692 Clcn1 Positive_regulation of Binding of Alms1 1 0.05 0.9 0 61.16
73 INT191059 Bcl2 Positive_regulation of Localization of Il12a 1 0.16 0.77 0 60.32
74 INT198004 MCL1 Negative_regulation of C12orf65 1 0.01 1.12 0 59.12
75 INT321890 Slc3a2 Regulation of Dkk1 1 0.01 0.93 0.04 57.60
76 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0 51.52
77 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 50.08
78 INT287697 QRFP Regulation of Gene_expression of TNF 1 0.40 1.23 0.42 49.28
79 INT191814 PDLIM7 Positive_regulation of TNFRSF8 1 0.08 1.16 0.08 47.40
80 INT191813 PDLIM7 Positive_regulation of FUT4 1 0.09 1.16 0.08 47.40
81 INT277984 Negative_regulation of Epo Positive_regulation of Localization of Ptprc 1 0.02 0.77 0.12 44.80
82 INT277986 Negative_regulation of Epo Positive_regulation of Localization of Cd34 1 0.08 0.77 0.12 44.32
83 INT128214 Binding of Il6 and Stap1 1 0.00 0 0.04 43.12
84 INT355364 Regulation of PTHLH Positive_regulation of Tnfsf11 1 0.04 1.51 0.19 41.68
85 INT355366 Regulation of CSF1 Positive_regulation of Tnfsf11 1 0.02 1.5 0.19 41.68
86 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08 41.36
87 INT355365 CSF1 Positive_regulation of Tnfsf11 1 0.03 1.49 0.19 38.72
88 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99 36.96
89 INT277693 Stat6 Positive_regulation of Positive_regulation of Casp3 1 0.01 1.01 0 36.04
90 INT277694 Cdkn1a Positive_regulation of Positive_regulation of Casp3 1 0.00 1.01 0 36.04
91 INT277691 Cdkn1a Negative_regulation of Positive_regulation of Casp3 1 0.00 1.01 0 35.64
92 INT198025 PIK3CA Positive_regulation of Gene_expression of MCL1 1 0.28 1.24 0 35.60
93 INT235693 Binding of Clcn1 and Gab2 1 0.19 2.96 0 35.52
94 INT355363 PTHLH Positive_regulation of Tnfsf11 1 0.04 1.47 0.19 33.76
95 INT277985 Epo Positive_regulation of Epc1 1 0.03 1.36 0.36 32.96
96 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 29.96
97 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09 28.08
98 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 0.01 0.46 0.09 27.56
99 INT192248 Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09 27.56
100 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 27.08
101 INT312304 Binding of JAK2 and VEGFA 1 0.30 0.82 0 24.80
102 INT347957 Binding of PTPRC and Cxcr4 1 0.39 0.37 0 22.20
103 INT352163 SNRPA Positive_regulation of Localization of IL10 1 0.06 0.87 0.23 19.68
104 INT198009 MTOR Regulation of HCC 1 0.09 1.1 0 17.92
105 INT290671 Binding of Socs3 and Stat3 2 0.23 1.59 0.45 17.48
106 INT290672 Stat3 Negative_regulation of Il6 1 0.08 0.4 0.18 15.72
107 INT320824 VEGFA Positive_regulation of DLL4 1 0.40 0.41 0 12.88
108 INT320825 VEGFA Positive_regulation of Gene_expression of DLL4 1 0.40 0.41 0 12.88
109 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23 12.08
110 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 7.84
111 INT206705 Negative_regulation of Binding of FLT1 and VEGFA 3 0.11 1.9 0 7.84
112 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 7.48
113 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
114 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
115 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
116 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
117 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08 5.00
118 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
119 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
120 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
121 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
122 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
123 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
124 INT346266 MTX1 Regulation of IL17A 1 0.08 1.33 0.89 5.00
125 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 5.00
126 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
127 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 5.00
128 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
129 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77 5.00
130 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74 5.00
131 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74 5.00
132 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
133 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7 5.00
134 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
135 INT308803 Binding of Pld1 and Pld2 1 0.13 1.11 0.59 5.00
136 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57 5.00
137 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
138 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53 5.00
139 INT194595 Binding of TNFSF10 and TNFRSF10B 4 0.15 9.3 0.53 5.00
140 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51 5.00
141 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51 5.00
142 INT207395 TNF Regulation of Gene_expression of Tnfsf11 1 0.11 0.91 0.49 5.00
143 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
144 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
145 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
146 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43 5.00
147 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
148 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41 5.00
149 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4 5.00
150 INT194596 Binding of HLA-DRB4 and TNFSF10 3 0.08 6 0.38 5.00
151 INT178217 IFNA1 Regulation of Cxcl10 1 0.01 0.86 0.37 5.00
152 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37 5.00
153 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
154 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
155 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
156 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 5.00
157 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
158 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
159 INT255944 MAPK14 Positive_regulation of Tauph 1 0.00 0.1 0.32 5.00
160 INT223962 Tnf Negative_regulation of Gene_expression of Bglap 1 0.21 1.21 0.32 5.00
161 INT223964 Tnf Negative_regulation of Bglap 1 0.21 1.2 0.32 5.00
162 INT255933 Tauph Positive_regulation of Rps6ka5 1 0.00 0.1 0.32 5.00
163 INT255945 MAPK14 Positive_regulation of Rps6ka5 1 0.06 0.1 0.32 5.00
164 INT255934 Tauph Positive_regulation of Map3k1 1 0.00 0.1 0.32 5.00
165 INT255946 MAPK14 Positive_regulation of Map3k1 1 0.04 0.1 0.32 5.00
166 INT316488 Il22 Positive_regulation of Il10 1 0.29 0.63 0.32 5.00
167 INT316483 Il22ra1 Positive_regulation of Il10 1 0.27 0.62 0.31 5.00
168 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
169 INT316487 Il22 Regulation of Il22ra1 1 0.12 0.61 0.31 5.00
170 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
171 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
172 INT219151 IL18 Positive_regulation of CASP1 1 0.01 1.05 0.3 5.00
173 INT223965 Binding of AMY2A and Bglap 1 0.05 1.5 0.28 5.00
174 INT292154 TNIP1 Positive_regulation of HIVEP1 1 0.01 0.97 0.27 5.00
175 INT219156 NLRP3 Positive_regulation of IL1B 1 0.01 1.03 0.27 5.00
176 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27 5.00
177 INT237928 BCL2 Positive_regulation of FAS 1 0.02 1.41 0.26 5.00
178 INT219194 Nlrp3 Positive_regulation of IL1B 1 0.04 1.03 0.26 5.00
179 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26 5.00
180 INT219193 Nlrp3 Positive_regulation of Positive_regulation of NLRP3 1 0.24 1.03 0.26 5.00
181 INT237925 BCL2 Positive_regulation of Protein_catabolism of PARP1 1 0.02 1.42 0.26 5.00
182 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26 5.00
183 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26 5.00
184 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
185 INT308805 Positive_regulation of Pld1 Positive_regulation of TNF 1 0.05 0.74 0.24 5.00
186 INT255942 Elk1 Regulation of Binding of ATF2 1 0.07 0.12 0.22 5.00
187 INT255842 CREB1 Regulation of Binding of ATF2 1 0.03 0.12 0.22 5.00
188 INT255837 ATF2 Regulation of Binding of CREB1 1 0.03 0.12 0.22 5.00
189 INT255941 ATF2 Regulation of Transcription of Elk1 1 0.07 0.12 0.22 5.00
190 INT255940 Elk1 Regulation of Transcription of CREB1 1 0.03 0.12 0.22 5.00
191 INT255835 ATF2 Regulation of Transcription of CREB1 1 0.03 0.12 0.22 5.00
192 INT316491 Socs3 Positive_regulation of Il11ra1 1 0.45 0.92 0.22 5.00
193 INT255839 CREB1 Regulation of Transcription of ATF2 1 0.03 0.12 0.22 5.00
194 INT255937 ATF2 Regulation of Binding of Elk1 1 0.07 0.12 0.22 5.00
195 INT255947 CREB1 Regulation of Transcription of Elk1 1 0.03 0.12 0.22 5.00
196 INT255943 Elk1 Regulation of Binding of CREB1 1 0.03 0.12 0.22 5.00
197 INT255939 Elk1 Regulation of Transcription of ATF2 1 0.07 0.12 0.22 5.00
198 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22 5.00
199 INT255938 CREB1 Regulation of Binding of Elk1 1 0.03 0.12 0.22 5.00
200 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Multiple Myeloma. They are ordered first by their pain relevance and then by number of times they were reported in Multiple Myeloma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
2 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29 100.00
3 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 100.00
4 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25 100.00
5 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 100.00
6 INT39212 Binding of Ttr 14 0.48 9.62 2.31 100.00
7 INT242131 Localization of Dkk1 5 0.79 6 0.76 99.98
8 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 99.98
9 INT10870 Regulation of IgG 67 0.59 43.27 12.74 99.98
10 INT133351 Regulation of Cd38 1 0.15 1.6 0.09 99.98
11 INT49286 Binding of IFNK 2 0.25 2.48 0.34 99.98
12 INT344977 Negative_regulation of Localization of Dkk1 2 0.42 2.57 0.3 99.98
13 INT201524 Localization of Wnt2 14 0.62 9.24 0.46 99.98
14 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.96
15 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 99.96
16 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 99.96
17 INT9995 Localization of C6orf25 13 0.69 6.48 2.29 99.96
18 INT701 Localization of IGHE 87 0.80 40.5 10.62 99.96
19 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 99.96
20 INT100757 Regulation of IGHD@ 1 0.41 0.39 0.1 99.96
21 INT84399 Negative_regulation of Igll1 1 0.35 0.83 0.06 99.96
22 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.92
23 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 99.92
24 INT17848 Binding of PTGS2 70 0.46 32.1 20.6 99.92
25 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23 99.88
26 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.84
27 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 99.84
28 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26 99.84
29 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45 99.84
30 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 99.84
31 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.80
32 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 99.80
33 INT61818 Positive_regulation of Ocln 6 0.23 4.11 0.22 99.78
34 INT61819 Positive_regulation of Ostf1 1 0.00 1.25 0.09 99.78
35 INT61817 Gene_expression of Rhoc 1 0.18 1.49 0.08 99.76
36 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 99.74
37 INT43907 Binding of CD79A 28 0.48 28.11 3.04 99.72
38 INT355345 Localization of NOG 1 0.37 16.14 0.71 99.70
39 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 99.70
40 INT340249 Positive_regulation of Positive_regulation of BGLAP 1 0.04 0.95 0.21 99.70
41 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 99.68
42 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82 99.68
43 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 99.68
44 INT117934 Gene_expression of Cd38 11 0.68 6.5 1.95 99.66
45 INT287485 Binding of NFKBIB 1 0.09 0.52 0.03 99.66
46 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 99.64
47 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12 99.64
48 INT101243 Regulation of STAT3 12 0.62 9.98 1.92 99.64
49 INT166403 Gene_expression of SPINT2 4 0.62 2.74 0.29 99.64
50 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 99.60
51 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.60
52 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 99.60
53 INT2409 Binding of SCT 7 0.48 2.69 1.94 99.60
54 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47 99.60
55 INT139796 Positive_regulation of Phosphorylation of IKBKG 1 0.25 0.89 0.11 99.60
56 INT139800 Positive_regulation of Protein_catabolism of IKBKG 1 0.25 0.89 0.11 99.60
57 INT139798 Positive_regulation of Phosphorylation of NFKBIA 1 0.04 0.88 0.11 99.60
58 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47 99.60
59 INT75648 Negative_regulation of CTD 4 0.07 3.91 0.25 99.60
60 INT298657 Negative_regulation of Gene_expression of COL18A1 1 0.41 1.34 0.07 99.58
61 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 99.58
62 INT155302 Positive_regulation of Car15 1 0.59 0.84 0.13 99.58
63 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.56
64 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 99.56
65 INT217168 Gene_expression of MIR21 30 0.55 30.86 0.62 99.56
66 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.56
67 INT217156 Positive_regulation of Gene_expression of MIR21 9 0.49 16.04 0.38 99.56
68 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 99.56
69 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 99.54
70 INT12082 Localization of IL6 365 0.81 241.78 105.78 99.52
71 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 99.52
72 INT44717 Gene_expression of TNFSF14 12 0.75 13.44 3.72 99.50
73 INT219296 Gene_expression of RGD1564184 1 0.01 1.83 0.03 99.48
74 INT69158 Localization of IL4 48 0.71 31.3 11.98 99.48
75 INT69155 Positive_regulation of Localization of IL4 13 0.40 10.18 3.56 99.48
76 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2 99.42
77 INT11235 Positive_regulation of IFNA2 27 0.69 15.32 2.57 99.40
78 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.36
79 INT142005 Gene_expression of COL18A1 6 0.75 4.53 0.62 99.30
80 INT9655 Regulation of Il6 98 0.62 70.92 31.95 99.30
81 INT129883 Gene_expression of Dkk1 56 0.77 45.42 12.52 99.28
82 INT223948 Negative_regulation of Gene_expression of Bglap 1 0.56 6.49 0.44 99.28
83 INT184301 Negative_regulation of Bglap 16 0.56 11.22 1.22 99.28
84 INT14778 Gene_expression of FCGR3A 25 0.75 16.25 3.86 99.26
85 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 99.24
86 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 99.20
87 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 99.18
88 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 99.16
89 INT139801 Phosphorylation of NFKB1 9 0.66 5.2 3.13 99.16
90 INT56077 Protein_catabolism of NFKB1 16 0.98 8.03 3.94 99.16
91 INT298661 Gene_expression of GDE1 5 0.04 3.42 0.26 99.14
92 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 99.12
93 INT178204 Regulation of Spa17 1 0.09 1.23 0 99.12
94 INT178208 Regulation of SPA17 1 0.03 1.29 0 99.12
95 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 99.08
96 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 99.08
97 INT77490 Positive_regulation of Tnnc1 85 0.68 43.54 9.07 99.08
98 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 99.04
99 INT86437 Binding of IL6 154 0.48 121.22 29.3 99.00
100 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 99.00
101 INT95669 Regulation of TNFRSF11A 7 0.56 10.01 0.94 99.00
102 INT118469 Gene_expression of Fgfr3 5 0.72 6.98 0.75 98.86
103 INT276327 Positive_regulation of Gene_expression of Fgfr3 2 0.43 1.83 0 98.86
104 INT15045 Gene_expression of Car15 2 0.26 1.67 0.21 98.84
105 INT15887 Gene_expression of Nbr1 39 0.77 23.91 7.34 98.84
106 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 98.84
107 INT110599 Gene_expression of Bglap 49 0.74 41.23 6.97 98.80
108 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09 98.80
109 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 98.80
110 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 98.76
111 INT111156 Negative_regulation of Dkk1 21 0.58 20.08 4.27 98.76
112 INT117921 Positive_regulation of Positive_regulation of MAPK14 9 0.44 9.93 4.18 98.68
113 INT163133 Gene_expression of ZBP1 28 0.65 18.59 1.25 98.64
114 INT10729 Positive_regulation of ENPEP 13 0.38 9.65 0.8 98.64
115 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 98.60
116 INT298667 Negative_regulation of Gene_expression of GDE1 1 0.03 1.02 0 98.60
117 INT55114 Gene_expression of CRS 42 0.58 26.86 4.69 98.60
118 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 98.56
119 INT161840 Gene_expression of Tnfrsf11b 17 0.78 12.44 2.63 98.52
120 INT10763 Localization of IL2 157 0.80 81.11 33.21 98.52
121 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 98.52
122 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 98.48
123 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 98.48
124 INT6852 Localization of TNF 883 0.81 705.95 270.84 98.46
125 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 98.44
126 INT245721 Localization of FRZB 6 0.78 4.3 0.6 98.36
127 INT97902 Gene_expression of AGGF1 17 0.11 13.45 2.51 98.32
128 INT298664 Gene_expression of MIR382 1 0.08 1.17 0.12 98.32
129 INT298666 Positive_regulation of Gene_expression of MIR382 1 0.06 1.17 0.12 98.32
130 INT298656 Positive_regulation of Gene_expression of MIR221 2 0.21 12.91 0.42 98.32
131 INT217182 Gene_expression of MIR221 4 0.58 9.33 0.27 98.32
132 INT217189 Gene_expression of MIR222 5 0.46 4.58 0.12 98.32
133 INT268552 Positive_regulation of Gene_expression of MIR222 4 0.21 4.06 0.12 98.32
134 INT185956 Gene_expression of Adamts4 2 0.58 0.97 0.29 98.32
135 INT100693 Regulation of Positive_regulation of STAT6 2 0.26 0.76 0.26 98.32
136 INT164587 Gene_expression of MCL1 94 0.75 124.05 5.39 98.28
137 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 98.28
138 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 98.26
139 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 98.24
140 INT186852 Localization of PILRB 1 0.01 1.38 0.08 98.24
141 INT277801 Positive_regulation of Ms4a1 2 0.44 1.95 0.06 98.24
142 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 98.22
143 INT9210 Regulation of IL6 166 0.62 125.61 49.95 98.20
144 INT19492 Regulation of B2M 16 0.60 10.97 2.55 98.20
145 INT22454 Regulation of Crp 213 0.62 160.67 49.24 98.20
146 INT22081 Regulation of Ceacam1 8 0.23 4.11 0.95 98.20
147 INT92311 Regulation of SIL1 7 0.44 6.2 1.61 98.20
148 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08 98.16
149 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 98.16
150 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77 98.16
151 INT139797 Negative_regulation of Protein_catabolism of IKBKG 1 0.29 0.89 0.11 98.16
152 INT139793 Protein_catabolism of IKBKG 1 0.50 0.88 0.11 98.16
153 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79 98.16
154 INT19509 Localization of Ifng 55 0.78 28.25 18.67 98.16
155 INT174816 Binding of IL6R 14 0.09 11.26 3.63 98.08
156 INT150528 Positive_regulation of Gene_expression of TNFSF10 26 0.67 30.71 5.43 98.04
157 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 98.00
158 INT340269 Regulation of Bw1 1 0.01 0.79 0.08 97.98
159 INT213740 Positive_regulation of Epc1 14 0.25 9.8 1.07 97.96
160 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 97.92
161 INT197979 Gene_expression of Prdx1 3 0.23 4.14 0.34 97.88
162 INT178186 Regulation of Stat3 7 0.44 6.23 0.74 97.84
163 INT290661 Regulation of Regulation of Stat3 1 0.29 0.36 0.14 97.84
164 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 97.76
165 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 97.74
166 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 97.72
167 INT305634 Localization of CCND1 1 0.07 2.69 0 97.72
168 INT14201 Localization of Igh-6 9 0.81 3.29 3.36 97.72
169 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 97.72
170 INT2132 Localization of SCT 29 0.81 8.39 5.43 97.70
171 INT114953 Gene_expression of NR1H4 23 0.29 16.58 2.02 97.68
172 INT198052 Positive_regulation of Gene_expression of MCL1 19 0.48 24.19 0.47 97.60
173 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 97.58
174 INT217820 Regulation of Negative_regulation of TP53 2 0.37 1.92 0 97.58
175 INT122004 Negative_regulation of Phosphorylation of NFKBIA 3 0.41 1.59 0.58 97.52
176 INT139794 Negative_regulation of Phosphorylation of IKBKG 1 0.21 0.89 0.11 97.52
177 INT139802 Phosphorylation of IKBKG 1 0.41 0.88 0.11 97.52
178 INT122003 Phosphorylation of NFKBIA 9 0.59 5.44 2.51 97.52
179 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 97.52
180 INT115157 Negative_regulation of Gene_expression of GDF15 12 0.51 6.99 2.43 97.52
181 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 97.40
182 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53 97.28
183 INT287052 Positive_regulation of Vav1 2 0.50 3.51 0 97.28
184 INT288804 Transcription of Vav1 1 0.68 3.37 0 97.28
185 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48 97.08
186 INT113111 Regulation of CXCR4 14 0.61 12.81 1.39 97.08
187 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 97.00
188 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 97.00
189 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 97.00
190 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 97.00
191 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 96.98
192 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 96.92
193 INT87420 Gene_expression of BCL2L1 56 0.75 48.84 5.32 96.92
194 INT173099 Localization of AGGF1 2 0.01 3.26 0.29 96.88
195 INT129318 Negative_regulation of NFKBIA 10 0.38 6.19 2.02 96.88
196 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19 96.84
197 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89 96.84
198 INT112962 Regulation of Positive_regulation of Ppara 17 0.45 10.63 2.58 96.84
199 INT74863 Gene_expression of PRDX1 3 0.50 2.16 0.1 96.68
200 INT86805 Localization of HGF 49 0.71 28.48 6.35 96.64
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