D:Multiple Organ Failure

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Disease Term
Synonyms Failure Multiple Organ, Mods, Multiple Organ Dysfunction Syndrome, MULTIPLE ORGAN FAILURES, ORGAN DYSFUNCTION SYNDROME MULTIPLE, Organ Failure Multiple
Documents 516
Hot Single Events 200
Hot Interactions 24

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Multiple Organ Failure. They are ordered first by their relevance to Multiple Organ Failure and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT195662 Binding of PROC and KAT8 1 0.10 2.25 0.12 100.00
2 INT296179 Pla2g2a Positive_regulation of Apcs 1 0.17 7.13 0.96 100.00
3 INT171126 Lta Positive_regulation of NOSTRIN 1 0.01 0.76 0.24 99.48
4 INT171124 Spg7 Positive_regulation of NOSTRIN 1 0.01 0.76 0.24 99.48
5 INT303126 Nos2 Positive_regulation of Gene_expression of Il6 1 0.13 4.38 0.34 98.60
6 INT303127 Gpt Positive_regulation of Gene_expression of Il6 1 0.09 4.38 0.34 98.60
7 INT320695 TNF Positive_regulation of Localization of Il1 1 0.05 1.38 0.44 98.20
8 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 97.84
9 INT195687 Binding of F13A1 and CA13 1 0.02 1.75 0 95.48
10 INT195777 THBD Positive_regulation of PROC 1 0.00 1.26 0.08 94.12
11 INT303123 Gpt Positive_regulation of Gene_expression of Mpo 1 0.22 0.99 0.08 93.52
12 INT303125 Nos2 Positive_regulation of Gene_expression of Mpo 1 0.34 0.99 0.08 93.52
13 INT303121 Gpt Positive_regulation of Gene_expression of Gpt 1 0.25 1.86 0.16 92.88
14 INT303129 Nos2 Positive_regulation of Gene_expression of Gpt 1 0.17 1.86 0.16 92.88
15 INT303122 Nos2 Positive_regulation of Gene_expression of Gpt 1 0.37 1.86 0.16 92.88
16 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34 92.76
17 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34 92.76
18 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34 92.76
19 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34 92.76
20 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34 92.76
21 INT195686 CA13 Positive_regulation of F13A1 1 0.03 1.75 0 91.40
22 INT195659 APC Positive_regulation of Gene_expression of PROC 1 0.26 0.31 0 91.12
23 INT310311 Tlr4 Positive_regulation of Gpt 1 0.05 1.15 0.12 89.56
24 INT195661 Binding of APC and PROC 1 0.23 0.89 0 89.52
25 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78 80.00
26 INT170121 ITGAL Regulation of CD44 1 0.07 1.07 0 80.00
27 INT170119 PECAM1 Regulation of Positive_regulation of ITGAL 1 0.01 1.07 0 80.00
28 INT170124 ITGAM Regulation of ITGB2 1 0.04 1.07 0 80.00
29 INT170120 PECAM1 Regulation of ITGAM 1 0.00 1.07 0 80.00
30 INT170118 PECAM1 Regulation of CD44 1 0.01 1.07 0 80.00
31 INT170123 ITGAL Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0 80.00
32 INT170125 ITGAM Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0 80.00
33 INT170126 PECAM1 Regulation of ITGB2 1 0.01 1.07 0 80.00
34 INT170116 ITGAM Regulation of CD44 1 0.07 1.07 0 80.00
35 INT170114 ITGAM Regulation of Positive_regulation of ITGAL 1 0.04 1.07 0 80.00
36 INT170115 PECAM1 Regulation of ITGAL 1 0.00 1.07 0 80.00
37 INT78590 Nos2 Positive_regulation of PTGS1 2 0.00 0.85 0.5 78.96
38 INT337572 TREM1 Regulation of CRP 1 0.05 0.99 0.07 71.76
39 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 70.00
40 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28 70.00
41 INT283256 MIR150 Regulation of Gene_expression of MYB 1 0.12 0.83 0 68.80
42 INT323613 Il1 Regulation of Localization of Hmgb1 1 0.10 0.75 0.19 66.72
43 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53 63.56
44 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18 63.56
45 INT222023 Gpx3 Regulation of Mapk8 1 0.01 1.43 0.18 63.56
46 INT310301 Casr Regulation of Tlr4 1 0.04 0.48 0.08 62.96
47 INT283258 MIR342 Positive_regulation of Gene_expression of IRF6 1 0.02 0.96 0 59.68
48 INT283254 MIR150 Positive_regulation of Gene_expression of IRF6 1 0.04 0.95 0 58.96
49 INT283259 MIR146B Positive_regulation of Gene_expression of IRF6 1 0.01 0.95 0 58.24
50 INT200558 Flt1 Regulation of Aliq1 1 0.02 0.97 0 54.84
51 INT303124 Binding of Fas and Tnfrsf10b 1 0.09 1.03 0.08 51.28
52 INT303128 Tnrc6a Regulation of Gene_expression of Nos2 1 0.00 0.57 0.14 50.00
53 INT222684 TEAD1 Negative_regulation of PROC 1 0.01 0.39 0.05 42.48
54 INT195666 Binding of PROC and THBD 2 0.40 2.42 0.56 38.44
55 INT195669 Binding of F2 and PROC 1 0.04 1.44 0.31 38.44
56 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 35.48
57 INT200517 Lar Regulation of Gene_expression of Crp 1 0.01 0.1 0 34.16
58 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32 30.48
59 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31 30.48
60 INT348784 Ins1 Positive_regulation of Irs1 1 0.09 3.47 0.44 25.68
61 INT205989 Binding of SLC7A7 and PDAP1 1 0.02 1.77 0 25.04
62 INT348785 Ins1 Positive_regulation of Phosphorylation of Akt1 1 0.17 3.5 0.42 23.36
63 INT283252 IRF6 Regulation of MIR155 1 0.01 1.04 0.03 22.92
64 INT283255 IRF6 Regulation of MIR15B 1 0.00 1.04 0.03 22.92
65 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07 22.60
66 INT283260 TNF Positive_regulation of TNF Regulation of MIR15B 1 0.01 1.03 0.03 21.56
67 INT283253 TNF Regulation of MIR15B 1 0.01 1.03 0.03 21.56
68 INT283257 TNF Regulation of MIR155 1 0.04 1.03 0.03 21.56
69 INT195770 Binding of CPB1 and MIF 1 0.01 0.47 0.15 20.96
70 INT300957 Binding of IL13 and Il4 1 0.01 0.58 0.48 19.44
71 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22 18.72
72 INT310626 Ambp Regulation of OTOR 1 0.15 1.04 0.14 8.60
73 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01 5.00
74 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 5.00
75 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 5.00
76 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 5.00
77 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
78 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15 5.00
79 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12 5.00
80 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
81 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99 5.00
82 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82 5.00
83 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79 5.00
84 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73 5.00
85 INT276598 Il10 Positive_regulation of Gene_expression of Paf 1 0.29 0.49 0.6 5.00
86 INT276597 Paf Positive_regulation of Il10 1 0.27 0.48 0.6 5.00
87 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6 5.00
88 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57 5.00
89 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55 5.00
90 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55 5.00
91 INT212806 Rngtt Negative_regulation of Gene_expression of Nos2 1 0.03 0.9 0.49 5.00
92 INT300956 Il4 Negative_regulation of IL8 1 0.02 0.37 0.48 5.00
93 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48 5.00
94 INT300959 Il4 Negative_regulation of TNF 1 0.03 0.37 0.48 5.00
95 INT300955 Il4 Negative_regulation of Il6 1 0.03 0.37 0.48 5.00
96 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 5.00
97 INT195769 MIF Regulation of Gene_expression of TP53I11 1 0.19 1.24 0.47 5.00
98 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
99 INT171123 TNF Positive_regulation of Localization of Spg7 1 0.01 1.35 0.46 5.00
100 INT195774 Binding of MIF and Cd74 1 0.02 1.15 0.46 5.00
101 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46 5.00
102 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
103 INT212809 Il6 Positive_regulation of Gene_expression of Nos2 1 0.08 0.75 0.43 5.00
104 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43 5.00
105 INT171125 Il1 Positive_regulation of Localization of TNF 1 0.00 1.22 0.41 5.00
106 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4 5.00
107 INT330598 Binding of Il6 and Fig4 1 0.11 1.78 0.4 5.00
108 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37 5.00
109 INT175016 Binding of REN and S100A6 2 0.11 1.13 0.37 5.00
110 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34 5.00
111 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 5.00
112 INT198642 GPI Positive_regulation of TNF 1 0.03 0.98 0.33 5.00
113 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31 5.00
114 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31 5.00
115 INT276602 Paf Positive_regulation of Gene_expression of Mthfd1 1 0.13 0.37 0.31 5.00
116 INT250738 Binding of hs and Serpinc1 1 0.00 0.46 0.3 5.00
117 INT198640 TNF Positive_regulation of ISYNA1 1 0.04 1.07 0.29 5.00
118 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26 5.00
119 INT198648 VCAM1 Positive_regulation of CADM1 1 0.00 1.1 0.25 5.00
120 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25 5.00
121 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25 5.00
122 INT300958 IL1B Positive_regulation of Il6 1 0.04 0.25 0.25 5.00
123 INT198644 TNF Positive_regulation of CADM1 1 0.02 1.07 0.24 5.00
124 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24 5.00
125 INT183945 INCENP Positive_regulation of Localization of IL6 1 0.00 0.2 0.23 5.00
126 INT295329 ecs Positive_regulation of TF 1 0.00 1.2 0.23 5.00
127 INT195705 Binding of SERPINC1 and SDC4 1 0.07 1.54 0.21 5.00
128 INT348789 Positive_regulation of Binding of MYD88 and Tlr4 1 0.46 0.93 0.2 5.00
129 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 0.00 0.87 0.2 5.00
130 INT334314 Tlr4 Positive_regulation of Gene_expression of Dusp1 1 0.01 0.37 0.19 5.00
131 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
132 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18 5.00
133 INT310302 Tlr4 Regulation of Positive_regulation of Serpina10 1 0.01 0.53 0.18 5.00
134 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
135 INT353041 IL4 Positive_regulation of Localization of IL1B 1 0.02 0.99 0.16 5.00
136 INT353036 IL4 Positive_regulation of Localization of IL10 1 0.03 0.99 0.16 5.00
137 INT353040 IL4 Positive_regulation of IL8 1 0.02 0.99 0.16 5.00
138 INT221899 Rb1 Positive_regulation of Transcription of Ccl20 1 0.01 0.62 0.16 5.00
139 INT353037 IL4 Positive_regulation of IL2 1 0.02 0.99 0.16 5.00
140 INT221908 Rb1 Positive_regulation of Transcription of TNIP2 1 0.01 0.62 0.16 5.00
141 INT310303 Serpina10 Positive_regulation of Hspa1a 1 0.02 0.53 0.16 5.00
142 INT83514 SERPINC1 Negative_regulation of F2 2 0.16 0.62 0.16 5.00
143 INT353038 IL4 Positive_regulation of Localization of IL2 1 0.02 0.99 0.16 5.00
144 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16 5.00
145 INT353039 IL4 Positive_regulation of Localization of IL8 1 0.02 0.99 0.16 5.00
146 INT198638 GPI Positive_regulation of Gene_expression of TNF 1 0.03 1.44 0.15 5.00
147 INT195708 SERPINC1 Negative_regulation of TNF 1 0.17 0.66 0.15 5.00
148 INT292750 Akt1 Positive_regulation of Bcl2 1 0.01 1.67 0.15 5.00
149 INT292749 Akt1 Positive_regulation of Ctnnd2 1 0.09 1.73 0.15 5.00
150 INT222022 Binding of Mmp8 and Mmp9 1 0.28 1.98 0.15 5.00
151 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15 5.00
152 INT223538 Binding of HAND1 and Tcf3 1 0.39 1.13 0.14 5.00
153 INT319963 Binding of IGFALS and Vcan 1 0.03 2.99 0.13 5.00
154 INT310313 Serpina10 Regulation of Gene_expression of Tlr4 1 0.00 0.25 0.13 5.00
155 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13 5.00
156 INT223539 Binding of HAND1 and Szf1 1 0.33 0.92 0.13 5.00
157 INT223530 Binding of Tcf3 and Szf1 1 0.33 0.92 0.13 5.00
158 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13 5.00
159 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13 5.00
160 INT212808 Rngtt Negative_regulation of Gene_expression of Ptger2 1 0.00 0.31 0.12 5.00
161 INT310305 Serpina10 Positive_regulation of Gene_expression of Tlr4 1 0.01 0.57 0.12 5.00
162 INT195710 SERPINC1 Positive_regulation of F2 1 0.08 0.69 0.11 5.00
163 INT348786 Tlr4 Positive_regulation of Mapk8 1 0.33 1.09 0.11 5.00
164 INT195711 Negative_regulation of SERPINC1 Positive_regulation of F2 1 0.08 0.7 0.11 5.00
165 INT212814 Rngtt Negative_regulation of Gene_expression of Tlr4 1 0.00 0.08 0.1 5.00
166 INT212807 Rngtt Negative_regulation of Nos2 1 0.03 0.08 0.1 5.00
167 INT212811 Rngtt Negative_regulation of Tlr4 1 0.00 0.08 0.1 5.00
168 INT250730 Hmgb1 Positive_regulation of Localization of TNF 1 0.08 0.92 0.09 5.00
169 INT250729 Crlf1 Positive_regulation of Localization of TNF 1 0.02 0.92 0.09 5.00
170 INT311811 Binding of REN and RASGRP1 1 0.16 0.68 0.08 5.00
171 INT195709 Negative_regulation of Binding of SERPINC1 and SDC4 1 0.09 0.24 0.08 5.00
172 INT310307 Tlr4 Positive_regulation of Transcription of Pus10 1 0.00 1.67 0.08 5.00
173 INT310310 Serpina10 Regulation of Gene_expression of Nos2 1 0.01 0.24 0.08 5.00
174 INT205244 Cldn3 Regulation of Gene_expression of Ocln 1 0.04 0.29 0.07 5.00
175 INT205237 Cldn2 Regulation of Gene_expression of Cldn5 1 0.03 0.29 0.07 5.00
176 INT205238 Cldn3 Regulation of Gene_expression of Cldn2 1 0.03 0.29 0.07 5.00
177 INT205228 Cldn5 Regulation of Gene_expression of Cldn1 1 0.03 0.29 0.07 5.00
178 INT223536 Binding of HAND1 and Hmga1 1 0.26 0.57 0.07 5.00
179 INT205245 Cldn5 Regulation of Gene_expression of Cldn3 1 0.02 0.29 0.07 5.00
180 INT205229 Cldn2 Regulation of Gene_expression of Ocln 1 0.07 0.29 0.07 5.00
181 INT205236 Cldn5 Regulation of Tjp1 1 0.03 0.28 0.07 5.00
182 INT205239 Cldn3 Regulation of Gene_expression of Cldn5 1 0.02 0.29 0.07 5.00
183 INT205240 Cldn3 Regulation of Tjp1 1 0.04 0.29 0.07 5.00
184 INT223525 Binding of Erv4 and Chd9 1 0.17 1.2 0.07 5.00
185 INT172382 AGT Positive_regulation of Localization of EDN1 1 0.03 0.34 0.07 5.00
186 INT205231 Cldn2 Regulation of Tjp1 1 0.07 0.29 0.07 5.00
187 INT205248 Cldn2 Regulation of Gene_expression of Tjp1 1 0.07 0.29 0.07 5.00
188 INT223531 Binding of Hmga1 and Tcf3 1 0.26 0.57 0.07 5.00
189 INT205232 Cldn5 Regulation of Gene_expression of Cldn2 1 0.03 0.29 0.07 5.00
190 INT205235 Cldn2 Regulation of Gene_expression of Cldn1 1 0.06 0.29 0.07 5.00
191 INT172381 AVP Positive_regulation of Localization of EDN1 1 0.01 0.34 0.07 5.00
192 INT205233 Cldn5 Regulation of Gene_expression of Ocln 1 0.03 0.28 0.07 5.00
193 INT223527 Binding of Chd9 and Li 1 0.36 1.2 0.07 5.00
194 INT205227 Cldn3 Regulation of Gene_expression of Cldn1 1 0.03 0.29 0.07 5.00
195 INT205247 Cldn3 Regulation of Gene_expression of Tjp1 1 0.04 0.29 0.07 5.00
196 INT205246 Cldn5 Regulation of Gene_expression of Tjp1 1 0.03 0.28 0.07 5.00
197 INT205234 Cldn2 Regulation of Gene_expression of Cldn3 1 0.03 0.29 0.07 5.00
198 INT335712 Binding of FASLG and CD8A 1 0.18 0.9 0.06 5.00
199 INT223521 Li Regulation of Imp3 1 0.03 0.82 0.06 5.00
200 INT335713 Binding of FAS and CD8A 1 0.32 0.9 0.06 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Multiple Organ Failure. They are ordered first by their pain relevance and then by number of times they were reported in Multiple Organ Failure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT174663 Positive_regulation of KAT8 4 0.11 3.45 0.22 100.00
2 INT303117 Positive_regulation of Kat8 1 0.13 1.52 0.11 100.00
3 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66 100.00
4 INT195675 Gene_expression of KAT8 1 0.30 1.38 0 100.00
5 INT303116 Gene_expression of Kat8 1 0.18 1.11 0.09 100.00
6 INT195676 Negative_regulation of KAT8 2 0.19 2.63 0.23 100.00
7 INT195678 Binding of KAT8 1 0.16 1.47 0.26 100.00
8 INT174662 Regulation of KAT8 2 0.10 1.09 0.18 100.00
9 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 99.96
10 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 99.88
11 INT195677 Regulation of Positive_regulation of PROC 1 0.22 1.57 0.06 99.88
12 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 99.84
13 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54 99.80
14 INT163290 Binding of MIF 9 0.31 7.57 2.8 99.80
15 INT5180 Binding of Serpinc1 27 0.36 13.39 2.47 99.76
16 INT149141 Negative_regulation of Skap2 3 0.34 0.43 0.25 99.76
17 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 99.70
18 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.58
19 INT6115 Positive_regulation of Pigm 82 0.64 16.96 25.73 99.58
20 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.56
21 INT226459 Binding of ST2 3 0.12 2.18 0.31 99.56
22 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 99.50
23 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4 99.44
24 INT39453 Negative_regulation of TCN2 12 0.59 3.98 2.13 99.40
25 INT12240 Negative_regulation of PRSS1 46 0.57 29.5 10.77 99.40
26 INT22782 Localization of PRSS1 25 0.81 14.44 7.34 99.40
27 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 99.28
28 INT20129 Regulation of Il1 53 0.53 44.14 19.89 99.28
29 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.14
30 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11 99.00
31 INT292008 Negative_regulation of CELSR2 1 0.01 1.73 0 98.96
32 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 98.88
33 INT102698 Binding of ACCS 54 0.42 66.73 9.06 98.68
34 INT171111 Regulation of Spg7 1 0.09 0.94 0.4 98.64
35 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 98.60
36 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 98.60
37 INT303118 Regulation of Gene_expression of Slc17a5 1 0.08 0.74 0 98.56
38 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09 98.56
39 INT14301 Binding of CSF2 82 0.48 67.95 8.98 98.24
40 INT49195 Binding of CSF3R 6 0.34 4.23 0.15 98.24
41 INT6852 Localization of TNF 883 0.81 705.95 270.84 98.20
42 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 97.92
43 INT96210 Positive_regulation of SLC6A2 5 0.49 1.99 2.34 97.90
44 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 97.84
45 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 97.80
46 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 97.80
47 INT191222 Binding of Amigo2 4 0.05 5.42 0.87 97.80
48 INT117495 Gene_expression of Pars2 13 0.38 7.93 4.24 97.78
49 INT61644 Gene_expression of Gc 16 0.70 11.35 1.95 97.68
50 INT16923 Positive_regulation of Tnni3 32 0.50 25.01 5.44 97.68
51 INT14186 Positive_regulation of Gene_expression of CPB1 2 0.39 3.46 0.42 97.64
52 INT121372 Positive_regulation of Gene_expression of MIF 17 0.60 14.78 4.73 97.64
53 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 97.64
54 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9 97.64
55 INT2385 Gene_expression of MIF 57 0.68 40.74 12.78 97.60
56 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 97.52
57 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 97.50
58 INT177953 Gene_expression of BTNL2 3 0.07 2.72 0.04 97.48
59 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.28
60 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21 97.28
61 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 97.26
62 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 97.26
63 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 97.20
64 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 97.16
65 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 97.12
66 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 97.12
67 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77 97.12
68 INT11937 Localization of Il6 228 0.81 139.83 64.39 97.08
69 INT19775 Localization of Il1 183 0.78 145.5 50.91 97.08
70 INT14182 Gene_expression of CPB1 26 0.67 10.06 1.9 97.00
71 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 97.00
72 INT171772 Binding of CPB1 13 0.32 9.92 0.75 96.96
73 INT124705 Binding of Il18 29 0.47 19.02 5.59 96.64
74 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16 96.60
75 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 96.56
76 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 96.56
77 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84 96.56
78 INT195693 Regulation of CA13 1 0.14 1.15 0 96.48
79 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 96.44
80 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 96.44
81 INT141015 Regulation of Il18 14 0.59 6.3 3.73 96.44
82 INT14152 Gene_expression of Slc17a5 46 0.61 20.01 15.9 96.24
83 INT1242 Negative_regulation of Slc17a5 14 0.42 4.06 5.78 96.24
84 INT145528 Negative_regulation of Gene_expression of Slc17a5 4 0.28 2.47 3.2 96.24
85 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 96.24
86 INT123813 Positive_regulation of Parp1 74 0.70 65.36 8.56 96.20
87 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6 96.20
88 INT76713 Regulation of Gene_expression of PECAM1 16 0.40 14.52 2.51 96.12
89 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 96.00
90 INT194992 Positive_regulation of CSF3R 1 0.46 1.61 0 96.00
91 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48 95.84
92 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 95.68
93 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 95.56
94 INT138844 Positive_regulation of CC2D1A 25 0.41 41.36 1.92 95.52
95 INT254144 Positive_regulation of Positive_regulation of CC2D1A 1 0.08 1.46 0 95.52
96 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 95.48
97 INT53262 Gene_expression of TSS 6 0.52 1.35 0.37 95.24
98 INT303119 Positive_regulation of Tnrc6a 1 0.01 0.74 0.08 95.20
99 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 95.16
100 INT158148 Positive_regulation of Gene_expression of Gc 2 0.36 1.89 0.23 95.16
101 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 95.16
102 INT250735 Binding of Radil 1 0.30 0.94 0.08 95.16
103 INT126583 Positive_regulation of PARP1 50 0.68 41.44 7.78 95.04
104 INT220329 Positive_regulation of IAH1 3 0.20 4.37 0 94.84
105 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 94.76
106 INT257824 Localization of PAFAH1B1 1 0.74 6.58 1 94.76
107 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 94.48
108 INT123142 Gene_expression of DEFB4A 54 0.76 36.14 10.02 94.44
109 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 94.12
110 INT180161 Binding of Nfasc 23 0.48 10.92 2.4 94.00
111 INT234509 Regulation of Ptpn22 1 0.01 0.94 0.18 93.68
112 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22 93.52
113 INT9908 Negative_regulation of IAPP 29 0.57 19.37 2.12 93.28
114 INT23921 Negative_regulation of NPPB 13 0.58 16.19 0.9 93.20
115 INT99001 Negative_regulation of Selp 23 0.59 16.68 4.74 93.04
116 INT3287 Gene_expression of Gpt 50 0.75 23.69 8.57 92.88
117 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 92.76
118 INT11807 Gene_expression of Il2 266 0.78 112 64.97 92.76
119 INT252991 Regulation of TAF9 2 0.44 3.54 0.08 92.72
120 INT65713 Localization of ICAM1 42 0.81 39.55 11.49 92.68
121 INT187738 Localization of SELE 4 0.64 8.13 0.64 92.68
122 INT12339 Localization of IL8 437 0.81 251.87 117.39 92.68
123 INT12082 Localization of IL6 365 0.81 241.78 105.78 92.68
124 INT88820 Positive_regulation of Gene_expression of F3 8 0.67 5.48 1.08 92.52
125 INT63164 Negative_regulation of Cst7 51 0.50 18.48 20.3 92.48
126 INT44540 Binding of GPT 3 0.36 6.14 0.23 92.48
127 INT101895 Binding of SLC17A5 5 0.36 7.08 0.18 92.48
128 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 92.44
129 INT3288 Positive_regulation of Gene_expression of Gpt 9 0.49 5.55 1.1 92.20
130 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 92.04
131 INT44003 Gene_expression of F3 40 0.75 27.92 8.29 92.00
132 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 91.96
133 INT28783 Positive_regulation of Gc 13 0.52 7.89 1.76 91.96
134 INT63074 Gene_expression of FOSB 19 0.53 13.58 4.91 91.96
135 INT64792 Positive_regulation of Gene_expression of ITGAM 39 0.69 23.21 6.71 91.88
136 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 91.88
137 INT70326 Positive_regulation of Gene_expression of ITGB2 24 0.67 15.42 3.86 91.88
138 INT195691 Phosphorylation of CA13 1 0.17 0.85 0 91.72
139 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 91.68
140 INT1168 Binding of PROC 62 0.38 44.15 9.04 91.64
141 INT16461 Negative_regulation of Gene_expression of PROC 13 0.24 4.39 2.17 91.60
142 INT61645 Negative_regulation of Gc 15 0.51 10.44 2.71 91.60
143 INT70173 Gene_expression of SLC6A2 6 0.65 5.26 1.76 91.56
144 INT6993 Negative_regulation of Mpo 72 0.59 61.83 19.51 91.52
145 INT53261 Gene_expression of exf 5 0.07 4.93 1.24 91.52
146 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 91.52
147 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 91.48
148 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 91.48
149 INT98107 Gene_expression of Adamts7 7 0.76 5.11 0.74 91.36
150 INT253175 Regulation of Positive_regulation of Parp1 2 0.52 0.97 0.08 91.20
151 INT331162 Negative_regulation of Gene_expression of AMIGO2 1 0.14 3.28 0.14 90.88
152 INT96271 Positive_regulation of Gene_expression of Mcpt1 30 0.53 21.34 11.06 90.88
153 INT179222 Gene_expression of AMIGO2 7 0.66 7.68 1.77 90.88
154 INT121370 Positive_regulation of MIF 22 0.70 17.79 6.08 90.48
155 INT99348 Negative_regulation of PARP1 38 0.58 30.96 3.36 90.28
156 INT66755 Transcription of Tnf 45 0.72 37.1 19.11 90.12
157 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 89.96
158 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 89.88
159 INT159472 Localization of NPPB 32 0.79 33.67 3.59 89.64
160 INT262317 Binding of TAF9 7 0.31 9.67 2.15 89.60
161 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99 89.56
162 INT63121 Binding of APC 29 0.41 23.02 3.8 89.52
163 INT173166 Negative_regulation of Binding of APC 3 0.40 3.01 0.19 89.52
164 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 89.52
165 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 89.52
166 INT62525 Positive_regulation of SELE 38 0.70 46 5.25 89.44
167 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 89.44
168 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 89.40
169 INT121374 Regulation of Gene_expression of MIF 2 0.39 1.01 0.29 89.32
170 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 89.12
171 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 89.12
172 INT89935 Regulation of SERPINC1 5 0.37 5.11 0.41 89.08
173 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69 88.96
174 INT191017 Localization of Cd79a 28 0.56 13.94 2.55 88.96
175 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 88.84
176 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 88.84
177 INT102659 Gene_expression of CSF3 32 0.77 21.93 2.39 88.64
178 INT283283 Negative_regulation of MIR150 5 0.41 4.16 0.55 88.56
179 INT88667 Negative_regulation of Gene_expression of F2 11 0.41 5.53 1.62 88.48
180 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 88.20
181 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84 88.04
182 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 88.00
183 INT61949 Regulation of Nos2 74 0.58 34.08 16.7 87.96
184 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 87.92
185 INT120752 Positive_regulation of Gene_expression of NPPB 17 0.67 16.4 2.21 87.88
186 INT181107 Gene_expression of Epcam 45 0.73 44.33 1.96 87.84
187 INT284117 Protein_catabolism of Epcam 2 0.43 3.01 0.31 87.84
188 INT9660 Regulation of TNF 363 0.62 312.94 139.99 87.72
189 INT219392 Positive_regulation of SLC5A8 1 0.41 2.4 0.23 87.56
190 INT248115 Positive_regulation of FABP2 8 0.49 4.91 1.39 87.48
191 INT255182 Positive_regulation of Gene_expression of FABP2 1 0.49 1.73 0.11 87.48
192 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 87.40
193 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 87.36
194 INT222688 Regulation of Positive_regulation of TEAD1 1 0.32 0.65 0.16 87.32
195 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 87.04
196 INT9655 Regulation of Il6 98 0.62 70.92 31.95 87.04
197 INT248112 Gene_expression of FABP2 3 0.75 4.78 0.58 86.76
198 INT62945 Negative_regulation of Gene_expression of SELL 12 0.58 12.86 3.23 86.76
199 INT2216 Gene_expression of SELL 92 0.77 59.29 17.71 86.76
200 INT10505 Gene_expression of Ptafr 18 0.62 10.7 6.83 86.72
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