D:Multiple Sclerosis

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Disease Term
Synonyms Arthritis Multiple Sclerosis, Chronic Relapsing Experimental Autoimmune Encephalomyelitis, CREAE, Disseminated Sclerosis, Eae, Experimental Autoimmune Encephalomyelitis, Ibd Solid Tumors Multiple Sclerosis, Ms Associated Retrovirus, Ms Multiple Sclerosis, MSRV, Multiple Sclerosis Acute Fulminating
Documents 370
Hot Single Events 200
Hot Interactions 173

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Multiple Sclerosis. They are ordered first by their relevance to Multiple Sclerosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 100.00
2 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42 100.00
3 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59 100.00
4 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27 100.00
5 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4 100.00
6 INT339070 Mog Positive_regulation of Eae1 1 0.01 3.81 0.61 100.00
7 INT154778 Cldn11 Positive_regulation of Eae1 4 0.12 3.24 1.03 100.00
8 INT49083 Mbp Positive_regulation of Eae1 1 0.02 2.96 1.71 100.00
9 INT188696 Binding of Cd40 and Eae1 1 0.05 1.57 0.21 100.00
10 INT188699 Binding of Cd40lg and Eae1 1 0.05 1.51 0.24 100.00
11 INT355878 Il17a Regulation of Eae1 1 0.06 1.52 0.54 100.00
12 INT333758 Hand1 Positive_regulation of Eae1 1 0.05 1.6 0.22 100.00
13 INT333762 Positive_regulation of thd Positive_regulation of Eae1 1 0.00 1.6 0.22 100.00
14 INT333760 thd Positive_regulation of Eae1 1 0.00 1.6 0.22 100.00
15 INT339967 Binding of Mog and Eae1 1 0.02 1.67 0.6 100.00
16 INT254635 Positive_regulation of Eae1 Positive_regulation of Gene_expression of Ccl2 1 0.15 1.07 0.27 100.00
17 INT334632 Binding of Kcna2 and Eae1 1 0.17 0.87 0.35 100.00
18 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19 100.00
19 INT353230 MOG Positive_regulation of Eae1 1 0.07 1.09 0.1 100.00
20 INT49085 Negative_regulation of MBP Positive_regulation of Eae1 1 0.00 1.51 0.87 100.00
21 INT49084 MBP Positive_regulation of Eae1 1 0.00 1.49 0.86 100.00
22 INT215942 Regulation of Mmp14 Regulation of Eae1 1 0.03 0.95 0.2 100.00
23 INT215944 Mmp14 Regulation of Eae1 1 0.03 0.95 0.2 100.00
24 INT339071 Binding of Mog and Eae1 1 0.00 1.65 0.06 100.00
25 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39 100.00
26 INT154780 Positive_regulation of Eae1 Negative_regulation of Cldn11 Positive_regulation of Eae1 1 0.03 0.72 0.18 100.00
27 INT154779 Eae1 Negative_regulation of Cldn11 Positive_regulation of Eae1 1 0.03 0.72 0.18 100.00
28 INT355879 Binding of Sry and Eae1 1 0.05 1.34 0.07 100.00
29 INT334685 Olig1 Regulation of Gene_expression of Plp1 1 0.17 0.55 0.06 100.00
30 INT334689 Olig1 Regulation of Gene_expression of Cnp 1 0.20 0.55 0.06 100.00
31 INT334682 Olig1 Regulation of Cnp 1 0.09 0.55 0.06 100.00
32 INT334686 Olig1 Regulation of Plp1 1 0.17 0.55 0.06 100.00
33 INT334688 Eae1 Regulation of Gene_expression of Plp1 1 0.05 0.5 0.06 100.00
34 INT334687 Eae1 Regulation of Gene_expression of Cnp 1 0.06 0.5 0.06 100.00
35 INT334683 Eae1 Regulation of Cnp 1 0.03 0.5 0.06 100.00
36 INT334684 Eae1 Regulation of Plp1 1 0.05 0.5 0.06 100.00
37 INT237776 Ifna1 Positive_regulation of Eae1 1 0.07 0.66 0.09 100.00
38 INT206212 UTS2R Positive_regulation of CD24 1 0.09 0.71 0.15 100.00
39 INT181454 Eae7 Regulation of Positive_regulation of Eae1 1 0.06 0.9 0.26 100.00
40 INT206537 Eae1 Regulation of Trem2 1 0.06 0.45 0.06 100.00
41 INT237774 Il12b Positive_regulation of Eae1 1 0.01 0.58 0.13 100.00
42 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 99.96
43 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54 99.96
44 INT241910 Binding of Alb and Alms1 1 0.02 0.52 0.13 99.92
45 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29 99.84
46 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87 99.84
47 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86 99.84
48 INT254636 Bdkrb2 Regulation of Gene_expression of Ccl2 1 0.15 1.15 0.43 99.70
49 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54 99.68
50 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 99.62
51 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 99.58
52 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04 99.44
53 INT334633 Binding of Cntnap1 and Nav1 1 0.10 1.36 1.48 99.34
54 INT187468 Alms1 Positive_regulation of H2-D1 1 0.02 0.32 0.11 99.08
55 INT355982 Binding of HLA-DQA2 and DCPS 1 0.00 1.33 0.26 98.92
56 INT222214 TFAM Positive_regulation of Cxcr1 1 0.03 1.13 0.37 98.88
57 INT350698 Mir326 Regulation of Ets1 1 0.01 1.27 0.4 98.88
58 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 0.22 0.8 0.26 98.84
59 INT241912 Cat Positive_regulation of Ros1 1 0.03 0.76 0.44 98.64
60 INT350701 Mthfd1 Regulation of Gene_expression of Cd4 1 0.03 1.46 0.33 98.54
61 INT300545 Il6 Positive_regulation of Gene_expression of Il1r1 1 0.02 0.42 0.11 98.52
62 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43 98.32
63 INT355877 Binding of Hand1 and Il4 1 0.14 0.25 0.22 98.28
64 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34 98.24
65 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 98.24
66 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12 98.24
67 INT298479 CD40LG Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.00 0.33 0.12 98.24
68 INT298478 IL4 Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 98.24
69 INT333765 Positive_regulation of Vdr Regulation of Gene_expression of Ccr6 1 0.21 0.48 0.12 98.20
70 INT241914 SOD1 Positive_regulation of Ros1 1 0.00 0.76 0.44 98.12
71 INT222178 SERPINB1 Regulation of ELANE 1 0.00 1.04 0.23 98.12
72 INT222184 SERPINB1 Regulation of PRTN3 1 0.00 1.04 0.23 98.12
73 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55 98.12
74 INT240537 Binding of Il12a and Ebi3 1 0.08 1.23 0.49 98.08
75 INT298474 IL4 Positive_regulation of HLA-DRB1 1 0.02 0.33 0.12 98.00
76 INT298473 IL4 Positive_regulation of CD80 1 0.06 0.33 0.12 98.00
77 INT222211 TFAM Positive_regulation of Ccr1 1 0.02 1.89 0.68 97.84
78 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56 97.84
79 INT298472 LPA Positive_regulation of Gene_expression of CXCL16 1 0.05 0.41 0.32 97.80
80 INT222181 TFAM Positive_regulation of XCR1 1 0.00 1.89 0.68 97.60
81 INT333761 Il27 Positive_regulation of Il10 1 0.16 0.58 0.13 97.56
82 INT241911 Binding of Cat and Ros1 1 0.03 0.85 0.27 97.40
83 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35 97.36
84 INT292530 Il10 Negative_regulation of Localization of Il1a 1 0.06 1.09 0.97 97.32
85 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7 97.28
86 INT240538 Il12a Positive_regulation of Phosphorylation of Stat4 1 0.11 0.76 0.22 97.28
87 INT240539 Il12a Positive_regulation of Stat3 1 0.11 0.75 0.22 97.28
88 INT240535 Il12a Positive_regulation of Tyk2 1 0.10 0.75 0.21 97.28
89 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21 97.28
90 INT206208 MRO Negative_regulation of CD24 1 0.02 1.87 0.32 97.24
91 INT206209 MRO Negative_regulation of Transcription of CD24 1 0.02 0.76 0.14 97.24
92 INT222180 Binding of HNF1B and TFAM 1 0.01 1.48 0.4 97.12
93 INT195212 Binding of CCR4 and Hand2 1 0.03 0.46 0.21 97.04
94 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33 96.88
95 INT296712 Binding of H2-K1 and GOPC 1 0.00 0.41 0.04 96.52
96 INT197776 Pla2g10 Regulation of Pla2g4a 1 0.18 0.61 0.08 96.40
97 INT222212 TFAM Negative_regulation of Cd28 1 0.02 1.17 0.39 96.00
98 INT246971 Binding of Clns1a and Csf2 1 0.10 1.31 0.22 95.84
99 INT355984 PDC Positive_regulation of Gene_expression of IL17A 1 0.06 1.57 0.31 95.84
100 INT355979 Negative_regulation of PDC Positive_regulation of Gene_expression of IL17A 1 0.06 1.57 0.31 95.84
101 INT246970 Binding of Clns1a and Dcps 1 0.05 0.42 0.18 95.84
102 INT197777 Pla2g10 Regulation of Pla2g2a 1 0.02 0.61 0.08 95.84
103 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33 95.68
104 INT285557 Eae2 Positive_regulation of Cia1 1 0.02 1.85 0.36 95.44
105 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33 95.28
106 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31 95.20
107 INT300544 Il22 Positive_regulation of Gene_expression of Mcpt1 1 0.02 1.15 0.47 94.96
108 INT246968 Binding of Csf2 and Dcps 1 0.14 0.42 0.18 94.88
109 INT349636 IL17A Positive_regulation of Gene_expression of IL4 1 0.06 1.28 0.5 94.72
110 INT222179 CDC5L Regulation of TFAM 1 0.01 0.26 0.13 94.48
111 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46 94.32
112 INT264137 IFNA1 Positive_regulation of Socs1 1 0.01 0.38 0.46 94.32
113 INT346915 Il12a Positive_regulation of Positive_regulation of IFN1@ 1 0.20 1.26 0.34 93.92
114 INT188698 Hand1 Positive_regulation of Localization of Mthfd1 1 0.06 0.71 0.2 93.68
115 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88 93.16
116 INT161225 Ccl2 Positive_regulation of Ccl2 Positive_regulation of Ccr2 1 0.57 2.09 1.88 93.16
117 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31 92.96
118 INT350693 Mir326 Positive_regulation of Regulation of thd 1 0.00 1.32 0.41 92.96
119 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 92.80
120 INT237777 Il23a Regulation of Localization of Il12a 1 0.19 0.93 0.19 92.76
121 INT340647 Regulation of Binding of Mkrn1 and Tg(CAG-EGFP)D4Nagy 1 0.09 0.38 0.03 92.64
122 INT298500 Alb Positive_regulation of Paf 1 0.01 0.34 0.15 92.32
123 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 92.24
124 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 92.24
125 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 92.12
126 INT300546 Binding of Il23a and Il1 1 0.01 0.5 0.25 92.12
127 INT340648 Binding of Mkrn1 and Tg(CAG-EGFP)D4Nagy 1 0.12 0.57 0.03 91.84
128 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 91.84
129 INT329310 Spp1 Positive_regulation of Gene_expression of IFN1@ 1 0.48 0.88 0.19 91.04
130 INT329309 Spp1 Regulation of Gene_expression of IFN1@ 1 0.26 0.82 0.19 91.04
131 INT333759 Il6 Positive_regulation of Il27 1 0.09 0.68 0.12 90.96
132 INT189849 Binding of Cd40 and Churc1 Regulation of Gene_expression of Ik 1 0.00 0.73 0.41 90.96
133 INT189843 Churc1 Regulation of Gene_expression of Ik 1 0.00 0.73 0.41 90.96
134 INT189846 Binding of Cd40 and Churc1 1 0.01 0.73 0.41 90.96
135 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18 90.72
136 INT285571 Binding of IL8 and Il17a 1 0.04 1.03 0.38 89.68
137 INT140386 Spp1 Positive_regulation of NFKB1 1 0.21 1.29 0.3 89.52
138 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3 89.52
139 INT237380 Binding of Cdkn2d and Il12b 1 0.01 0.45 0.26 89.52
140 INT355985 IDO1 Positive_regulation of Gene_expression of DCPS 1 0.02 1.21 0.23 88.72
141 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 88.48
142 INT264135 Socs1 Positive_regulation of Protein_catabolism of TOLLIP 1 0.00 0.33 0.41 88.36
143 INT335311 Binding of IRF6 and SLC15A4 1 0.00 0.23 0.19 88.36
144 INT237379 Binding of Ebi3 and Il27 2 0.05 1.71 0.82 86.96
145 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53 86.88
146 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27 86.88
147 INT355981 IFNAR2 Positive_regulation of IDO1 1 0.01 1.13 0.23 86.84
148 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34 86.80
149 INT333764 Il6 Regulation of Gene_expression of Il6ra 1 0.02 0.52 0.12 86.68
150 INT300549 Il1 Regulation of Gene_expression of Irf4 1 0.01 0.63 0.33 86.68
151 INT335346 SLC15A4 Negative_regulation of Gene_expression of Fos 1 0.02 0.23 0.23 86.52
152 INT139683 Binding of Cldn11 and 2410016O06Rik 1 0.02 1.06 0.4 86.12
153 INT254638 Bdkrb2 Positive_regulation of Positive_regulation of Bdkrb1 1 0.09 0.96 0.48 85.76
154 INT329305 Spp1 Positive_regulation of Gene_expression of Il12a 1 0.12 0.88 0.16 85.68
155 INT139684 Binding of Cd4 and 2410016O06Rik 1 0.02 1.05 0.4 85.52
156 INT288162 Igh-Dex Positive_regulation of Gopc 1 0.02 0.63 0.41 84.24
157 INT298475 LPA Positive_regulation of Gene_expression of IL8 1 0.07 0.38 0.15 84.20
158 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 84.16
159 INT163974 Trpv1 Negative_regulation of Gene_expression of Tnf 1 0.34 0.24 0.35 83.68
160 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 83.28
161 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14 82.80
162 INT285558 Binding of Il11ra1 and Il27 1 0.05 1.1 0.33 82.72
163 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 82.40
164 INT241913 AAVS1 Positive_regulation of Cat 1 0.04 0.46 0.1 82.28
165 INT242447 Prf1 Positive_regulation of Positive_regulation of Gfap 1 0.35 0.16 0.06 82.16
166 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67 81.92
167 INT318074 Polr1a Negative_regulation of Gene_expression of Il2 1 0.00 0.46 0.08 80.80
168 INT275653 MIR18B Regulation of MIR96 1 0.06 0.53 0.07 80.56
169 INT275661 Mir599 Regulation of MIR96 1 0.01 0.53 0.07 80.56
170 INT275651 MIR493 Regulation of MIR96 1 0.06 0.53 0.07 80.56
171 INT275650 MIR193A Regulation of MIR96 1 0.13 0.48 0.07 80.56
172 INT332489 Binding of JAM3 and SGPP2 1 0.27 0.24 0.04 80.08
173 INT332483 Binding of JAG1 and SGPP2 1 0.21 0.23 0.04 80.08
174 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33 78.72
175 INT215945 Binding of Mmp14 and Timp2 Positive_regulation of Mmp2 1 0.11 0.4 0.84 78.72
176 INT236362 Binding of Gfap and Itgam 1 0.23 2.31 0.2 78.64
177 INT188707 Binding of IFNA1 and Hand1 1 0.01 0.56 0.32 78.64
178 INT335291 SLC15A4 Negative_regulation of NFATC1 1 0.01 0.45 0.51 77.52
179 INT206535 Binding of Trem2 and Tg(CAG-EGFP)D4Nagy 1 0.03 0.5 0.27 77.28
180 INT143504 IFNG Positive_regulation of Gene_expression of Aif1 1 0.04 1.26 0.51 77.04
181 INT329304 Spp1 Negative_regulation of Gene_expression of Il10 1 0.06 0.93 0.13 76.64
182 INT197496 Binding of Apoe and Lrp1 4 0.22 2.32 0.46 76.48
183 INT264134 Binding of IFNA1 and Tlr4 1 0.01 1.5 0.22 75.92
184 INT121963 Itpka Negative_regulation of Positive_regulation of Phospho1 1 0.01 0.59 0.22 75.48
185 INT297338 Apoe Regulation of Gnb5 1 0.06 1.12 0.27 74.40
186 INT243675 Mp Negative_regulation of Gene_expression of IL-17 1 0.01 0.93 0.45 73.96
187 INT222183 Binding of HDLBP and PLA2G15 1 0.01 0.7 0.57 73.92
188 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81 72.80
189 INT274449 Binding of Cd4 and H2 2 0.05 1.25 0.1 72.44
190 INT243677 IL-17 Regulation of IFNA1 1 0.01 0.21 0.16 72.28
191 INT236363 Regulation of Binding of Ptprc and Tlr4 1 0.25 1.23 0.06 71.16
192 INT231507 Binding of Ptprc and Tlr4 2 0.21 1.22 0.06 71.16
193 INT334631 Igf1r Positive_regulation of Phosphorylation of Akt1 1 0.19 0.5 0.18 71.12
194 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83 70.88
195 INT355983 CSF2 Regulation of Gene_expression of DCPS 1 0.02 0.84 0.25 70.56
196 INT270657 Casp8 Regulation of Localization of Ins1 1 0.03 0.68 0 69.64
197 INT335300 SLC15A4 Regulation of CA2 1 0.00 0.19 0.12 68.16
198 INT329303 Spp1 Positive_regulation of Localization of Il12a 1 0.12 0.92 0.12 67.12
199 INT335293 SLC15A4 Regulation of NA 1 0.00 0.19 0.12 66.88
200 INT278218 Hand1 Negative_regulation of Gene_expression of Il4 1 0.20 0.37 0.08 66.48

Single Events

The table below shows the top 200 pain related interactions that have been reported for Multiple Sclerosis. They are ordered first by their pain relevance and then by number of times they were reported in Multiple Sclerosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 100.00
2 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 100.00
3 INT141656 Regulation of Eae1 22 0.39 32.62 8.12 100.00
4 INT154094 Negative_regulation of Eae1 25 0.18 30.42 7.89 100.00
5 INT154093 Positive_regulation of Gene_expression of Eae1 23 0.20 26.08 5.84 100.00
6 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 100.00
7 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85 100.00
8 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
9 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 100.00
10 INT77310 Gene_expression of Aif1 89 0.78 50.49 33.68 100.00
11 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 100.00
12 INT70835 Gene_expression of Aimp1 18 0.77 17.18 9.36 100.00
13 INT215925 Positive_regulation of Positive_regulation of Eae1 7 0.17 7.81 2.05 100.00
14 INT109558 Binding of Eae1 9 0.25 10.36 3.16 100.00
15 INT188674 Negative_regulation of Positive_regulation of Eae1 9 0.15 7.54 2.34 100.00
16 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14 100.00
17 INT206513 Localization of Eae1 7 0.26 8.32 3.02 100.00
18 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
19 INT173512 Positive_regulation of Gene_expression of Alms1 12 0.44 8.66 1.95 100.00
20 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01 100.00
21 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 100.00
22 INT68279 Positive_regulation of Gene_expression of Csf2 30 0.67 16.31 6.88 100.00
23 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
24 INT164532 Regulation of Gene_expression of Eae1 4 0.18 2.53 1.5 100.00
25 INT181373 Negative_regulation of Gene_expression of Ccr2 5 0.59 5.92 1.44 100.00
26 INT237762 Regulation of Positive_regulation of Eae1 3 0.03 3.15 0.96 100.00
27 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
28 INT181402 Negative_regulation of Ccr1 8 0.42 7 2.2 100.00
29 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 100.00
30 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 100.00
31 INT108559 Gene_expression of Pol 46 0.45 30.07 1.14 100.00
32 INT334675 Regulation of Negative_regulation of Eae1 1 0.08 2.28 0.33 100.00
33 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
34 INT47714 Regulation of Nqo1 12 0.24 11.12 1.71 100.00
35 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 100.00
36 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 100.00
37 INT173519 Positive_regulation of Localization of IFNA1 27 0.49 24.48 3.9 100.00
38 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49 100.00
39 INT122902 Positive_regulation of Gene_expression of Spp1 54 0.70 56.3 6.33 100.00
40 INT215922 Negative_regulation of Gene_expression of Eae1 3 0.06 1.96 1.1 100.00
41 INT13302 Binding of PTAFR 20 0.48 7.03 3.7 100.00
42 INT68576 Positive_regulation of Positive_regulation of CSF2 8 0.40 8.1 2.83 100.00
43 INT47490 Regulation of Positive_regulation of CSF2 2 0.39 1.42 0.88 100.00
44 INT75263 Protein_catabolism of Eae1 2 0.21 2.13 0.57 100.00
45 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 100.00
46 INT49774 Binding of DRD2 48 0.48 17.42 20.73 100.00
47 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 100.00
48 INT254627 Positive_regulation of Localization of Eae1 1 0.17 1.93 0.75 100.00
49 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66 100.00
50 INT187154 Regulation of SLEB1 5 0.03 6.59 1.32 100.00
51 INT355874 Positive_regulation of rsl 1 0.20 1.34 0.18 100.00
52 INT355875 Regulation of Eae13 1 0.19 1.43 0.2 100.00
53 INT340630 Negative_regulation of Ly6c1 1 0.37 1.4 0.3 100.00
54 INT215917 Regulation of Regulation of Mmp14 1 0.33 0.95 0.2 100.00
55 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 100.00
56 INT215932 Transcription of Eae1 1 0.10 1.21 0.11 100.00
57 INT246953 Localization of Dcps 5 0.32 1.89 1.06 100.00
58 INT206760 Localization of Nqo1 8 0.09 15.76 2.4 100.00
59 INT141657 Regulation of Regulation of Eae1 2 0.04 0.83 0.44 100.00
60 INT270030 Negative_regulation of Positive_regulation of Hmox1 3 0.30 2.49 0.47 100.00
61 INT58459 Negative_regulation of Localization of IL2 13 0.41 6.46 4.88 100.00
62 INT97141 Regulation of Gene_expression of CD83 6 0.55 2.66 0.4 100.00
63 INT246951 Positive_regulation of Gene_expression of Dcps 1 0.20 0.5 0.39 100.00
64 INT187161 Binding of SLEB1 9 0.05 11.8 1.09 100.00
65 INT257525 Regulation of Localization of Eae1 1 0.03 0.56 0.21 100.00
66 INT234160 Localization of Igfals 4 0.16 3.8 0.74 100.00
67 INT181392 Positive_regulation of Eae7 1 0.19 0.89 0.25 100.00
68 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 100.00
69 INT349067 Negative_regulation of Binding of Eae1 1 0.01 0.95 0.11 100.00
70 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81 99.98
71 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.98
72 INT108558 Transcription of Pol 5 0.35 4.67 0.64 99.98
73 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35 99.98
74 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 99.98
75 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74 99.98
76 INT206518 Gene_expression of Trem2 1 0.78 16.79 6.92 99.96
77 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 99.96
78 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 99.96
79 INT215923 Positive_regulation of Mog 8 0.19 9.86 3.17 99.96
80 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58 99.96
81 INT215929 Negative_regulation of Mmp15 1 0.30 5.42 3.54 99.96
82 INT47391 Positive_regulation of Paf 16 0.62 12.31 3.79 99.96
83 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 99.96
84 INT11807 Gene_expression of Il2 266 0.78 112 64.97 99.96
85 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9 99.96
86 INT79227 Negative_regulation of Gene_expression of Icam1 45 0.59 41.65 14.97 99.96
87 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 99.96
88 INT127023 Negative_regulation of Gene_expression of Vcam1 24 0.59 20.39 6.28 99.96
89 INT112270 Negative_regulation of Cntnap1 4 0.57 1.74 1.76 99.96
90 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.96
91 INT44320 Positive_regulation of Cldn11 5 0.39 2.95 1.81 99.96
92 INT187462 Positive_regulation of Localization of Vcam1 1 0.40 0.89 0.04 99.96
93 INT181409 Positive_regulation of Ccl20 8 0.54 3.41 1.81 99.96
94 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37 99.96
95 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01 99.92
96 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 99.92
97 INT206525 Regulation of Trem2 4 0.62 4.65 1.26 99.92
98 INT153271 Localization of Ccl3 7 0.81 11.29 7.14 99.92
99 INT235933 Regulation of Mog 2 0.24 3.85 1.3 99.92
100 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 99.92
101 INT334674 Regulation of Olig1 1 0.27 2.13 0.82 99.92
102 INT215915 Gene_expression of Mmp24 1 0.24 1.93 1.25 99.92
103 INT334679 Regulation of Gene_expression of Olig1 1 0.27 0.89 0.24 99.92
104 INT25134 Positive_regulation of CD9 3 0.49 3.38 0.66 99.92
105 INT181408 Localization of Tnpo1 2 0.13 2.4 1.16 99.92
106 INT125013 Regulation of S100a8 9 0.26 7.93 3.21 99.92
107 INT181018 Binding of S100a8 20 0.45 22.14 3.18 99.92
108 INT49474 Gene_expression of Hpse 24 0.55 20.11 10.03 99.90
109 INT317596 Positive_regulation of Gene_expression of Hpse 3 0.14 2.24 0.6 99.90
110 INT156975 Gene_expression of SLEB1 31 0.65 38.83 6.73 99.90
111 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73 99.90
112 INT106616 Gene_expression of PSMB9 35 0.72 28.4 2.29 99.88
113 INT246954 Binding of Dcps 4 0.15 2.95 0.7 99.88
114 INT3520 Binding of Csf2 27 0.43 9.68 6.08 99.88
115 INT6018 Positive_regulation of PSMB9 7 0.60 4.36 1.33 99.88
116 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67 99.88
117 INT246949 Positive_regulation of Positive_regulation of Mog 1 0.26 0.42 0.3 99.88
118 INT30011 Negative_regulation of Sepp1 18 0.54 4.65 3.54 99.88
119 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 99.86
120 INT211700 Negative_regulation of Mri1 5 0.29 2.06 1.04 99.86
121 INT99898 Gene_expression of Mmp14 37 0.56 28.54 16.39 99.84
122 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 99.84
123 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97 99.84
124 INT246955 Gene_expression of Dcps 19 0.31 12.26 2.12 99.84
125 INT334680 Negative_regulation of Olig1 1 0.43 9.5 2.32 99.84
126 INT116398 Gene_expression of Mog 25 0.77 23.11 6.33 99.84
127 INT199692 Gene_expression of Mkrn1 48 0.75 15.2 3.84 99.84
128 INT181344 Gene_expression of Ccr6 28 0.61 24.34 9.78 99.84
129 INT235938 Binding of Mog 3 0.34 9.61 3.09 99.84
130 INT215926 Regulation of Gene_expression of Mmp14 1 0.45 5.33 3.15 99.84
131 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 99.84
132 INT133156 Binding of Cd40 77 0.48 45.92 13.77 99.84
133 INT340638 Gene_expression of Ly6c1 1 0.67 7.9 2.17 99.84
134 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 99.84
135 INT181378 Negative_regulation of Gene_expression of Ccl5 12 0.46 9.64 3.59 99.84
136 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 99.84
137 INT99897 Positive_regulation of Gene_expression of Mmp14 7 0.36 6.33 2.51 99.84
138 INT280564 Negative_regulation of Gene_expression of PSMB9 5 0.54 5.99 0.41 99.84
139 INT333746 Negative_regulation of Gene_expression of Ccr6 1 0.46 3.76 0.94 99.84
140 INT334676 Regulation of Negative_regulation of Olig1 1 0.27 2.39 0.55 99.84
141 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 99.84
142 INT246948 Regulation of Gene_expression of Dcps 1 0.18 1.02 0.05 99.84
143 INT71608 Regulation of Positive_regulation of Paf 1 0.35 1.04 0.83 99.84
144 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 99.84
145 INT28122 Gene_expression of MSC 111 0.58 26.83 6.57 99.84
146 INT69621 Positive_regulation of Positive_regulation of Hpse 7 0.42 4.1 2.85 99.84
147 INT13415 Positive_regulation of Hpse 58 0.70 24.9 25.53 99.84
148 INT48246 Gene_expression of PLP1 18 0.64 10.33 4.73 99.84
149 INT135835 Positive_regulation of Gene_expression of PLP1 1 0.21 2.44 0.41 99.84
150 INT170296 Regulation of Gene_expression of Gopc 33 0.38 12.49 6 99.84
151 INT181396 Transcription of Csf2 15 0.48 6.38 2.17 99.84
152 INT97144 Negative_regulation of CD83 5 0.39 2.28 0.54 99.84
153 INT119852 Gene_expression of RPS15AP36 1 0.03 0.56 0.29 99.84
154 INT157941 Gene_expression of IL-17 65 0.65 20.39 9.89 99.82
155 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 99.82
156 INT34057 Negative_regulation of Gene_expression of IFNA1 65 0.58 43.46 17.25 99.82
157 INT103261 Positive_regulation of Nav1 68 0.70 24.25 39.27 99.80
158 INT87239 Localization of Il12a 51 0.75 31.95 12.05 99.80
159 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 99.80
160 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 99.80
161 INT237772 Localization of Il23a 5 0.42 4.16 1.34 99.80
162 INT197775 Regulation of Pla2g10 1 0.17 2.26 0.39 99.80
163 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 99.80
164 INT181405 Gene_expression of Ccl20 26 0.65 23.02 9.46 99.80
165 INT102843 Negative_regulation of PDC 5 0.57 4.26 1.82 99.80
166 INT191803 Positive_regulation of CD24 6 0.70 5.49 0.43 99.80
167 INT355992 Negative_regulation of Negative_regulation of PDC 1 0.21 1.62 0.32 99.80
168 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83 99.78
169 INT6130 Positive_regulation of Regulation of POMC 6 0.69 3.57 1.7 99.78
170 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 99.76
171 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 99.76
172 INT106189 Regulation of Il12a 18 0.44 12.4 5.3 99.76
173 INT92234 Regulation of CXCL10 15 0.42 8.37 5.09 99.76
174 INT77945 Regulation of Gene_expression of Il12a 19 0.58 6.55 6.4 99.76
175 INT113384 Regulation of Gene_expression of Nav1 20 0.62 8.57 16.15 99.76
176 INT181342 Gene_expression of Eae18 1 0.53 1.32 0.43 99.76
177 INT82929 Gene_expression of Plat 58 0.78 26.96 13.85 99.76
178 INT181384 Positive_regulation of Ccr6 3 0.55 2.53 1.24 99.76
179 INT200189 Negative_regulation of Igfals 7 0.24 4.19 1.39 99.76
180 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 99.74
181 INT4929 Binding of Mbp 25 0.48 18.01 9.41 99.74
182 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06 99.74
183 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 99.72
184 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 99.72
185 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 99.72
186 INT157943 Positive_regulation of IL-17 10 0.58 6.65 2.43 99.72
187 INT243655 Positive_regulation of Gene_expression of IL-17 11 0.58 3.06 1.45 99.72
188 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01 99.72
189 INT74241 Positive_regulation of Gene_expression of EDA 3 0.49 4.93 2.24 99.72
190 INT56404 Gene_expression of EDA 16 0.75 7.09 4.24 99.72
191 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 99.72
192 INT243665 Positive_regulation of Gene_expression of Cd8a 2 0.12 1.91 0.51 99.72
193 INT82444 Positive_regulation of Gene_expression of Cd4 10 0.47 4.36 3.12 99.72
194 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 99.72
195 INT215918 Negative_regulation of Positive_regulation of Mmp14 1 0.31 0.45 0.56 99.72
196 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 99.70
197 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 99.70
198 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28 99.68
199 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 99.68
200 INT81443 Positive_regulation of Vcam1 29 0.63 28.4 6.35 99.68
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