D:Muscle Disease

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pChart

Disease Term
Synonyms DISEASE OF SKELETAL MUSCLE, Disease Of The Skeletal Muscle, DISORDER OF MUSCLE, DISORDER OF SKELETAL MUSCLE, Disorder Of Smooth Muscle, DISORDER OF THE MUSCLE, Disorder Of The Skeletal Muscle, MUSCLE DISORDER, Muscle Disorders, Muscular Disease, Muscular Diseases
Documents 1272
Hot Single Events 200
Hot Interactions 15

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Muscle Disease. They are ordered first by their relevance to Muscle Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT271071 Binding of ACTA1 and Hypism 1 0.00 1.54 0.15 100.00
2 INT289788 Binding of Comp and Scn8a 1 0.16 1.37 0 99.98
3 INT217486 Binding of PDB1 and Sqstm1 1 0.03 1.19 0.08 99.98
4 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 99.96
5 INT331966 Binding of DES and SACM1L 1 0.01 1.86 0.36 99.88
6 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13 98.46
7 INT94890 MBTPS1 Positive_regulation of SNAP25 1 0.16 0.39 0.2 98.20
8 INT13519 Binding of HLA-DQA1 and HLA-DRB4 1 0.03 0.88 0.05 96.60
9 INT277308 Upf1 Regulation of Regulation of Celf1 1 0.00 1.05 0 96.52
10 INT17088 Binding of Ttpa and C9orf3 2 0.38 0.7 0.22 93.84
11 INT265501 Binding of SGCB and SGCD 1 0.00 1.41 0 89.24
12 INT21620 Binding of Ttpa and Vldlr 1 0.22 0.27 0.12 89.16
13 INT312290 Binding of Col9a1 and Matn3 1 0.02 0.65 0 88.84
14 INT289878 Binding of MMD and SEPN1 1 0.16 1.27 0 87.44
15 INT114077 Gtf3a Positive_regulation of Tfam 1 0.09 1.08 0.09 85.96
16 INT36328 Binding of AMPD1 and Hmgcl 1 0.01 1.02 0 79.96
17 INT232902 Binding of YWHAQ and Krt18 1 0.34 0.96 0.07 79.52
18 INT232901 Regulation of Binding of YWHAQ and Krt18 1 0.41 0.96 0.07 79.52
19 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 76.52
20 INT289791 Comp Regulation of Gene_expression of Col7a1 1 0.20 0.21 0 76.08
21 INT205589 Binding of PPT2 and COQ2 1 0.04 1.02 0.07 75.44
22 INT277315 Binding of Insr and Mbnl1 1 0.18 1.1 0 73.60
23 INT277310 Binding of Tnnt2 and Mbnl1 1 0.18 1.1 0 73.04
24 INT271025 Binding of Car2 and Casq1 1 0.03 0.7 0.03 70.88
25 INT271027 Binding of RYR1 and Car2 1 0.03 0.46 0 70.88
26 INT311432 Binding of TSHR and TAOK1 1 0.12 1.05 0.07 70.32
27 INT335743 Binding of PDB1 and Salpa1 1 0.01 1.66 0.09 69.84
28 INT335742 Binding of PDB1 and Dpyd 1 0.02 1.75 0.09 69.84
29 INT323654 Igfbp1 Negative_regulation of Binding of Igf1 and Igfbp1 1 0.21 1.14 0.29 69.76
30 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29 69.76
31 INT311298 Binding of DMPK and Mbnl1 1 0.43 0.54 0 68.96
32 INT289795 Binding of COMP and Comp 1 0.02 0.99 0 68.08
33 INT217478 Binding of Tnfrsf11a and Traf6 1 0.39 1.22 0.17 62.84
34 INT271348 Binding of CHKB and MB 1 0.01 1.01 0 61.84
35 INT142346 Igf1 Positive_regulation of Mapk3 1 0.75 0.33 0.06 61.52
36 INT142345 Negative_regulation of Igf1 Positive_regulation of Akt1 1 0.42 0.33 0.06 61.52
37 INT142348 Igf1 Positive_regulation of Akt1 2 0.50 1.16 0.06 61.52
38 INT142347 Negative_regulation of Igf1 Positive_regulation of Mapk3 1 0.46 0.33 0.06 61.52
39 INT292363 Rbmy1a1 Positive_regulation of Bhr1 1 0.05 1.04 0.12 61.24
40 INT289794 Binding of Comp and Fn1 1 0.07 2.59 0.12 55.44
41 INT312289 Binding of Col9a1 and Comp 1 0.09 1.38 0 53.60
42 INT267217 Gene_expression of Hspb8 Negative_regulation of Positive_regulation of Casp3 1 0.14 2.8 0.04 52.60
43 INT312291 Binding of Comp and Matn3 1 0.06 1.37 0 52.16
44 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0 50.04
45 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12 50.00
46 INT289790 Binding of Col7a1 and Comp 1 0.14 1.2 0.12 50.00
47 INT289789 Comp Positive_regulation of Gene_expression of Rer1 1 0.55 0.8 0.03 50.00
48 INT335736 Binding of Map1lc3a and Map1lc3b 1 0.19 0.36 0 50.00
49 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92 48.16
50 INT80659 Positive_regulation of INS Positive_regulation of APC 1 0.32 0.65 0 46.92
51 INT80660 INS Positive_regulation of APC 1 0.32 0.65 0 46.56
52 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08 43.72
53 INT327052 Gene_expression of Akt1 Positive_regulation of Gene_expression of Myod1 1 0.19 0.18 0 43.36
54 INT327053 Gene_expression of Akt1 Positive_regulation of Gene_expression of Txlnb 1 0.04 0.18 0 43.36
55 INT339272 VDR Positive_regulation of Gene_expression of KRT20 1 0.00 0.07 0.05 43.12
56 INT259703 Binding of MYBPC3 and HELT 1 0.04 1.64 0 40.16
57 INT80661 INS Positive_regulation of GYS1 1 0.13 0.29 0 39.60
58 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18 38.52
59 INT80909 Binding of TNC and TNNC1 1 0.12 0.07 0 37.12
60 INT80910 Binding of TNC and TNNI3 1 0.21 0.07 0 36.48
61 INT254909 ARSH Regulation of Sumf1 1 0.00 0.9 0.04 33.96
62 INT254908 ARSH Regulation of Eef1a1 1 0.00 0.89 0.04 33.96
63 INT279107 Binding of COMP and MATN3 1 0.41 1.43 0.2 33.28
64 INT279109 Binding of COL9A2 and MATN3 1 0.48 0.64 0.1 33.28
65 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 27.36
66 INT139619 Binding of Usp14 and Gm16381 1 0.04 1.01 0 25.00
67 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 19.32
68 INT271026 Binding of Car2 and Dnahc8 1 0.00 0.44 0 16.32
69 INT204943 Il6 Regulation of Slc39a14 1 0.00 0.54 0.36 11.28
70 INT316414 Binding of LDLR and T2dm2 1 0.00 1.54 0 7.12
71 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
72 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
73 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65 5.00
74 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
75 INT328981 Binding of Mup1 and Cts 1 0.14 1.05 0.88 5.00
76 INT328982 Binding of Igfals and Cts 1 0.05 0.92 0.8 5.00
77 INT328976 Binding of Cst7 and Cts 1 0.08 0.92 0.79 5.00
78 INT328979 Binding of Muted and Cts 1 0.03 0.9 0.78 5.00
79 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77 5.00
80 INT190788 Adcy8 Positive_regulation of Adcy1 1 0.23 0.77 0.77 5.00
81 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 5.00
82 INT328978 Binding of Igfals and Muted 1 0.02 0.85 0.73 5.00
83 INT328980 Binding of Cst7 and Igfals 1 0.06 0.85 0.73 5.00
84 INT328975 Binding of Igfals and Mup1 1 0.11 0.85 0.73 5.00
85 INT328983 Binding of Cst7 and Muted 1 0.04 0.84 0.73 5.00
86 INT328977 Binding of Cst7 and Mup1 1 0.18 0.84 0.73 5.00
87 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72 5.00
88 INT328974 Binding of Muted and Mup1 1 0.06 0.83 0.71 5.00
89 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61 5.00
90 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61 5.00
91 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61 5.00
92 INT276217 Pdk1 Positive_regulation of Positive_regulation of Insr 1 0.05 0.1 0.6 5.00
93 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51 5.00
94 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51 5.00
95 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5 5.00
96 INT339275 Il6 Regulation of KRT20 1 0.00 3.11 0.49 5.00
97 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47 5.00
98 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46 5.00
99 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
100 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4 5.00
101 INT276214 Binding of Nos2 and Nfkb1 1 0.12 0.31 0.34 5.00
102 INT276209 Negative_regulation of Binding of Nos2 and Nfkb1 1 0.14 0.31 0.34 5.00
103 INT344036 Binding of NOS1 and SPTB 1 0.01 0.31 0.32 5.00
104 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
105 INT271350 MPO Positive_regulation of TIMP1 1 0.05 1.66 0.29 5.00
106 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 5.00
107 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28 5.00
108 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 5.00
109 INT277317 Binding of Celf1 and Slc6a11 1 0.19 0.06 0.26 5.00
110 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
111 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23 5.00
112 INT89612 Binding of FABP3 and MB 3 0.34 1.49 0.22 5.00
113 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
114 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
115 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21 5.00
116 INT277318 Upf1 Positive_regulation of Atxn8os 1 0.01 0.77 0.21 5.00
117 INT188985 Binding of MKLN1 and CHPT1 1 0.06 0 0.19 5.00
118 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
119 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
120 INT317895 Fos Regulation of Transcription of Egr1 1 0.41 1.03 0.17 5.00
121 INT317897 Egr1 Regulation of Transcription of Fosb 1 0.34 1.08 0.17 5.00
122 INT317889 Fos Regulation of Transcription of Fosb 1 0.30 1.08 0.17 5.00
123 INT317892 Egr1 Regulation of Transcription of Fos 1 0.41 1.03 0.17 5.00
124 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
125 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15 5.00
126 INT316769 Binding of H2-K1 and Hspa9 1 0.08 1.02 0.15 5.00
127 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 5.00
128 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 5.00
129 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14 5.00
130 INT326605 Binding of HTR1A and KCNH2 1 0.00 0.45 0.14 5.00
131 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14 5.00
132 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 5.00
133 INT329847 PPARA Regulation of Gene_expression of CREB3L3 1 0.17 0.84 0.13 5.00
134 INT271345 Negative_regulation of PIGF Negative_regulation of FLT1 1 0.02 1.17 0.13 5.00
135 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
136 INT344705 Nr1h2 Regulation of Scarb1 1 0.04 1.53 0.12 5.00
137 INT344706 Nr1h2 Regulation of Abca1 1 0.03 2.39 0.12 5.00
138 INT300570 Binding of IL1RN and SUGT1P2 1 0.01 0.43 0.12 5.00
139 INT344713 Nr1h2 Regulation of Abcg1 1 0.03 2.39 0.12 5.00
140 INT3751 Binding of GOT1 and PIK3C2A 1 0.08 0.68 0.12 5.00
141 INT3752 Binding of GOT1 and LDHA 1 0.11 0.68 0.12 5.00
142 INT317891 Binding of Akt1 and Mtf1 1 0.21 1.04 0.11 5.00
143 INT317893 Binding of Eef1a1 and Mmp9 1 0.02 1.04 0.11 5.00
144 INT317888 Binding of Eef1a1 and Pik3r1 1 0.01 1.04 0.11 5.00
145 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11 5.00
146 INT317896 Binding of Mmp9 and Mtf1 1 0.36 1.04 0.11 5.00
147 INT317887 Binding of Mtf1 and Pik3r1 1 0.25 1.04 0.11 5.00
148 INT317898 Binding of Akt1 and Eef1a1 1 0.01 1.04 0.11 5.00
149 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11 5.00
150 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
151 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 5.00
152 INT217470 Traf6 Positive_regulation of Ngf 1 0.36 0.52 0.1 5.00
153 INT217476 Nup62 Positive_regulation of Ngf 1 0.37 0.52 0.1 5.00
154 INT271343 Binding of CRP and PAPPA 1 0.20 0.86 0.1 5.00
155 INT199436 Binding of Capns1 and Cysltr1 1 0.00 0.79 0.1 5.00
156 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
157 INT217477 Traf6 Positive_regulation of Binding of Nup62 1 0.32 0.47 0.09 5.00
158 INT277316 Upf1 Positive_regulation of Slc6a11 1 0.01 0.47 0.09 5.00
159 INT271349 ACCS Positive_regulation of PAPPA 1 0.06 0.87 0.09 5.00
160 INT241040 Slc8a1 Negative_regulation of Gene_expression of Ca2 1 0.15 1.35 0.09 5.00
161 INT277320 Upf1 Positive_regulation of Upf1 Positive_regulation of Slc6a11 1 0.00 0.47 0.09 5.00
162 INT271347 Negative_regulation of Binding of TNNT2 and ACCS 1 0.01 0.67 0.08 5.00
163 INT271354 MPO Regulation of Gene_expression of CRP 1 0.16 1.74 0.08 5.00
164 INT277319 Gene_expression of Celf1 Positive_regulation of Positive_regulation of Slc6a11 1 0.24 0.08 0.08 5.00
165 INT271346 Binding of TNNT2 and ACCS 1 0.01 0.67 0.08 5.00
166 INT277313 Negative_regulation of Mbnl1 Positive_regulation of Positive_regulation of Slc6a11 1 0.52 0.08 0.08 5.00
167 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
168 INT271351 MPO Positive_regulation of CRP 1 0.07 1.69 0.08 5.00
169 INT232897 Binding of Rab27a and SAMSN1 1 0.00 0.73 0.08 5.00
170 INT304349 Binding of HBN1 and MIR133B 1 0.00 0.29 0.07 5.00
171 INT329897 PPARA Regulation of Cpt2 1 0.09 0.05 0.07 5.00
172 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
173 INT356379 DMD Positive_regulation of Negative_regulation of Utrn 1 0.54 0.84 0.07 5.00
174 INT304346 MIR133B Regulation of Gene_expression of MIR206 1 0.05 0.78 0.07 5.00
175 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 5.00
176 INT267214 Hspb8 Negative_regulation of Cryab 1 0.32 1.56 0.06 5.00
177 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00
178 INT271355 PGF Positive_regulation of PIGF 1 0.01 0.99 0.06 5.00
179 INT311296 Akt1 Positive_regulation of Gene_expression of Clcn1 1 0.11 0 0.05 5.00
180 INT217472 Binding of Nup62 and Mul1 1 0.12 0 0.05 5.00
181 INT217471 Binding of Nup62 and Traf6 1 0.26 0 0.05 5.00
182 INT275126 Binding of CSTB and IGHG3 1 0.00 0.49 0.05 5.00
183 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05 5.00
184 INT217468 Positive_regulation of Binding of Nup62 and Mul1 1 0.16 0 0.05 5.00
185 INT237351 Binding of Mtm1 and Gopc 1 0.19 0.17 0.05 5.00
186 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
187 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05 5.00
188 INT287222 Cytip Regulation of Transcription of Insig1 1 0.02 0.56 0.05 5.00
189 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05 5.00
190 INT328667 Binding of CD40LG and CSF2 1 0.16 0.59 0.05 5.00
191 INT328668 Binding of CSF2 and IGHG3 1 0.03 0.59 0.05 5.00
192 INT106823 Binding of MBP and PAPPA 2 0.17 3.89 0.05 5.00
193 INT217467 Binding of Nup62 and Tnfrsf11a 1 0.31 0 0.05 5.00
194 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05 5.00
195 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
196 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04 5.00
197 INT329849 PPARA Regulation of AGXT 1 0.03 0.06 0.04 5.00
198 INT217474 Tnfrsf11a Regulation of Gene_expression of Tnfsf11 1 0.41 1.2 0.04 5.00
199 INT276211 Pdpk1 Regulation of Akt1 1 0.07 0.72 0.04 5.00
200 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Muscle Disease. They are ordered first by their pain relevance and then by number of times they were reported in Muscle Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 100.00
2 INT262317 Binding of TAF9 7 0.31 9.67 2.15 100.00
3 INT184306 Localization of Comp 2 0.69 5.1 0.12 100.00
4 INT252991 Regulation of TAF9 2 0.44 3.54 0.08 100.00
5 INT121774 Binding of ACTA1 4 0.47 2.31 0.85 100.00
6 INT9549 Regulation of CHKB 25 0.47 13.61 3.2 100.00
7 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 100.00
8 INT315561 Regulation of ISCU 2 0.35 1.1 0 100.00
9 INT140233 Positive_regulation of DYSF 1 0.41 0.74 0.15 100.00
10 INT249052 Protein_catabolism of SMN1 1 0.02 1.98 0.1 100.00
11 INT289780 Positive_regulation of Localization of Dnajc1 1 0.08 0.84 0 100.00
12 INT45510 Binding of Scn8a 4 0.31 3.89 0.25 99.98
13 INT289776 Localization of Dnajc1 1 0.11 1.86 0.08 99.98
14 INT121338 Binding of MTUS1 5 0.07 3.41 0.16 99.98
15 INT93017 Binding of PDB1 8 0.36 6.36 0.51 99.98
16 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16 99.96
17 INT44997 Positive_regulation of Eef1a2 16 0.40 8.84 5.37 99.96
18 INT63164 Negative_regulation of Cst7 51 0.50 18.48 20.3 99.96
19 INT743 Negative_regulation of Salpa1 16 0.57 8.75 3.1 99.96
20 INT174848 Gene_expression of ISCU 2 0.59 2.79 0.08 99.92
21 INT37715 Positive_regulation of MSC 34 0.48 10.52 2.92 99.92
22 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 99.90
23 INT9138 Positive_regulation of Negative_regulation of PFKM 2 0.47 1.32 0.14 99.90
24 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 99.88
25 INT2442 Localization of Mb 38 0.80 24.74 6.33 99.86
26 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 99.86
27 INT11737 Negative_regulation of Ampd1 2 0.13 1.26 0.18 99.84
28 INT184621 Regulation of ALDOB 1 0.01 1.15 0 99.80
29 INT63222 Negative_regulation of MGAM 8 0.43 4.33 0.37 99.78
30 INT28320 Negative_regulation of Abo 16 0.58 5.69 4.7 99.76
31 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.76
32 INT262315 Negative_regulation of PLEKHM2 1 0.01 4.1 0.09 99.72
33 INT127034 Binding of Egfl7 4 0.04 2.21 0.54 99.72
34 INT316920 Negative_regulation of Dmd 1 0.42 0.33 0.03 99.72
35 INT267203 Negative_regulation of Cryab 2 0.29 3.98 0 99.70
36 INT58571 Positive_regulation of ALDOB 6 0.49 5.63 0.53 99.70
37 INT9140 Negative_regulation of PFKM 14 0.59 12.67 3.61 99.68
38 INT312284 Binding of Comp 1 0.30 3.08 0 99.66
39 INT175417 Binding of SACM1L 8 0.29 6.06 0.22 99.64
40 INT180497 Binding of MRI1 45 0.42 28.35 14.77 99.64
41 INT96128 Localization of Eef1a2 4 0.14 1.59 0.47 99.64
42 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 99.56
43 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 99.54
44 INT2090 Negative_regulation of Gaa 5 0.21 3.43 0.4 99.48
45 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.48
46 INT312287 Gene_expression of Col9a1 1 0.21 2.94 0 99.46
47 INT35528 Negative_regulation of Eef1a2 7 0.38 2.6 1.34 99.46
48 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.44
49 INT120216 Regulation of RYR2 2 0.28 1.03 0.22 99.42
50 INT84701 Binding of HSP90B2P 8 0.47 7.37 1.29 99.36
51 INT316763 Positive_regulation of Positive_regulation of Hspa9 1 0.40 1.7 0.17 99.36
52 INT184305 Gene_expression of Comp 53 0.77 31.66 2.2 99.34
53 INT24800 Negative_regulation of AMPD1 44 0.59 21.19 6.76 99.32
54 INT142340 Positive_regulation of Chkb 3 0.47 6.44 0.38 99.24
55 INT49706 Positive_regulation of TNNT2 22 0.69 12.65 1.56 99.24
56 INT11814 Positive_regulation of Alb 43 0.63 31.71 6.28 99.24
57 INT17081 Binding of Ttpa 7 0.27 2.12 0.34 99.22
58 INT47434 Gene_expression of Tnnt2 14 0.60 10.4 1.37 99.20
59 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17 99.20
60 INT20462 Binding of ESR1 210 0.44 102.7 26.34 99.10
61 INT53704 Negative_regulation of Col7a1 42 0.35 22.4 6.88 99.04
62 INT289782 Regulation of Negative_regulation of Col7a1 1 0.20 0.25 0 99.04
63 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 99.04
64 INT134966 Localization of Col7a1 23 0.42 16.4 5.24 98.96
65 INT80857 Negative_regulation of Cpt2 19 0.42 12.1 1.6 98.96
66 INT187090 Positive_regulation of Localization of Col7a1 4 0.07 3.16 0.51 98.96
67 INT112328 Negative_regulation of PHKG1 2 0.46 0.83 0.1 98.96
68 INT284528 Negative_regulation of POLG2 2 0.17 2.19 0.33 98.92
69 INT9254 Negative_regulation of LDHA 23 0.43 13.3 2.2 98.92
70 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 98.92
71 INT164634 Regulation of EGFL7 4 0.09 3.06 1.15 98.92
72 INT9139 Regulation of Negative_regulation of PFKM 1 0.27 0.77 0.16 98.92
73 INT227519 Positive_regulation of Hspa9 22 0.55 16.38 3.83 98.88
74 INT98609 Negative_regulation of PYGM 11 0.43 6.21 0.6 98.84
75 INT261265 Gene_expression of PYGM 2 0.17 1.96 0.24 98.84
76 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 98.84
77 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 98.78
78 INT88425 Negative_regulation of DYSF 4 0.57 4.68 0.83 98.76
79 INT37253 Negative_regulation of PTPRC 12 0.37 6.13 1.26 98.74
80 INT315562 Gene_expression of GLRX5 1 0.69 4.92 0 98.74
81 INT3364 Binding of SGCG 87 0.47 31.93 17.24 98.72
82 INT340876 Positive_regulation of Negative_regulation of Cryab 1 0.20 0.62 0 98.68
83 INT237337 Binding of Cav3 3 0.44 2.63 0.11 98.68
84 INT275876 Binding of Chkb 1 0.04 0.54 0.46 98.60
85 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 98.58
86 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 98.52
87 INT68187 Gene_expression of TNNT2 21 0.67 10.22 1.64 98.52
88 INT166812 Gene_expression of Asph 1 0.22 0.69 0.17 98.48
89 INT166810 Gene_expression of Casq1 2 0.10 2.16 0.08 98.48
90 INT193632 Positive_regulation of ARVD4 2 0.01 2.73 0.11 98.40
91 INT202818 Negative_regulation of Nagk 1 0.04 0.75 0.03 98.32
92 INT202819 Negative_regulation of Dse 1 0.00 0.74 0.03 98.32
93 INT312285 Positive_regulation of Positive_regulation of Chkb 1 0.24 1.02 0 98.32
94 INT165880 Regulation of SLCO1B1 1 0.60 0.28 0.1 98.32
95 INT28894 Positive_regulation of PLK2 3 0.50 3.77 0.69 98.26
96 INT166813 Regulation of Asph 1 0.09 0.37 0.1 98.24
97 INT166811 Regulation of Casq1 3 0.04 1.18 0.1 98.24
98 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 98.24
99 INT212594 Positive_regulation of Phosphorylation of polymerase 1 0.01 0.83 0 98.24
100 INT128927 Positive_regulation of Gene_expression of Hspb2 6 0.68 5.09 0.57 98.22
101 INT340897 Positive_regulation of Hspb2 3 0.34 1.86 0.26 98.22
102 INT812 Localization of INS 1026 0.81 515.6 145.31 98.20
103 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 98.20
104 INT169582 Phosphorylation of POLG 2 0.54 1.98 0.18 98.04
105 INT212586 Phosphorylation of polymerase 3 0.08 2.64 0 98.04
106 INT60209 Transcription of RYR1 3 0.69 3.06 0.16 97.96
107 INT166809 Binding of Casq1 1 0.05 0.34 0.08 97.96
108 INT289892 Gene_expression of SEPN1 3 0.42 1.17 0.13 97.92
109 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 97.92
110 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 97.92
111 INT331968 Positive_regulation of Gene_expression of SEPN1 1 0.31 1 0.13 97.92
112 INT158175 Positive_regulation of Gene_expression of RYR1 2 0.48 1.35 0.13 97.92
113 INT88416 Positive_regulation of Gene_expression of ACTA1 2 0.67 1.05 0.13 97.92
114 INT331971 Positive_regulation of Gene_expression of DNM2 1 0.31 1 0.13 97.92
115 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64 97.92
116 INT71918 Gene_expression of ACTA1 16 0.75 7.73 1.45 97.92
117 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 97.92
118 INT38886 Positive_regulation of Regulation of ICT1 1 0.34 0.91 0.1 97.84
119 INT38883 Regulation of Positive_regulation of ICT1 1 0.20 0.91 0.1 97.84
120 INT8841 Positive_regulation of ICT1 3 0.34 2.27 0.17 97.84
121 INT22812 Positive_regulation of PTRH1 4 0.49 3.06 0.43 97.84
122 INT227102 Gene_expression of Mtm1 2 0.77 9.58 0.26 97.72
123 INT182852 Regulation of AAVS1 4 0.12 4.6 1.03 97.72
124 INT267929 Negative_regulation of Localization of Egfl7 1 0.01 0.32 0 97.68
125 INT326607 Positive_regulation of STC1 1 0.20 3 0.2 97.64
126 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 97.60
127 INT128928 Gene_expression of Hspb2 15 0.76 9.42 2.52 97.56
128 INT157302 Positive_regulation of Map1lc3a 27 0.66 11.31 0.79 97.52
129 INT156850 Binding of VDR 40 0.47 24.86 4.87 97.52
130 INT211756 Phosphorylation of Mmd 1 0.17 1.44 0.03 97.48
131 INT211753 Negative_regulation of ACADS 1 0.03 1.49 0.08 97.44
132 INT4437 Positive_regulation of ABCB7 11 0.68 11.26 1.33 97.40
133 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 97.28
134 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 97.24
135 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31 97.24
136 INT133905 Gene_expression of Ncam1 24 0.78 10.2 4.62 97.20
137 INT265507 Negative_regulation of SGCD 1 0.12 0.68 0 97.20
138 INT256690 Binding of Hsp90b1 11 0.30 5.94 0.55 97.16
139 INT316761 Positive_regulation of Binding of Hsp90b1 1 0.35 0.8 0.05 97.16
140 INT344588 Negative_regulation of Gene_expression of GPT 1 0.41 0.62 0 97.14
141 INT180117 Localization of Egfl7 4 0.04 2.88 0.07 97.12
142 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 97.12
143 INT38884 Regulation of PTRH1 1 0.14 0.91 0.1 97.06
144 INT36893 Negative_regulation of Coq10a 36 0.55 22.24 5.47 97.04
145 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 96.98
146 INT334158 Positive_regulation of DTNA 1 0.10 1.85 0.12 96.96
147 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 96.96
148 INT24458 Negative_regulation of PDB1 8 0.41 4.5 1.5 96.96
149 INT255112 Negative_regulation of Mbnl1 22 0.58 8.5 0.45 96.96
150 INT155775 Gene_expression of PDB1 12 0.65 10.18 0.41 96.96
151 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 96.92
152 INT94891 Protein_catabolism of SNAP25 2 0.55 0.19 0.1 96.92
153 INT38885 Regulation of ICT1 3 0.20 2.02 0.26 96.88
154 INT130015 Positive_regulation of Localization of CHKB 3 0.48 1.72 0.39 96.88
155 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 96.80
156 INT181034 Localization of Zmat3 3 0.06 1.51 0.28 96.80
157 INT94347 Gene_expression of DYSF 4 0.75 3.25 0.41 96.60
158 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88 96.60
159 INT256673 Positive_regulation of Hsp90b1 12 0.49 8.49 0.68 96.60
160 INT50295 Regulation of Mtpn 13 0.26 7.54 3.77 96.52
161 INT38561 Regulation of SEMG1 19 0.51 3.75 3.66 96.52
162 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 96.48
163 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 96.48
164 INT47992 Gene_expression of Scn8a 14 0.78 4.15 3.83 96.48
165 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 96.44
166 INT130669 Regulation of Gene_expression of CYP2C9 2 0.25 0.69 0.44 96.40
167 INT165876 Regulation of Gene_expression of Tpmt 1 0.06 0.28 0.1 96.40
168 INT289877 Binding of Lama2 1 0.36 0.48 0 96.40
169 INT61904 Gene_expression of CST7 3 0.53 3.22 2.53 96.36
170 INT88464 Negative_regulation of CST7 11 0.31 5.33 2.17 96.36
171 INT23620 Negative_regulation of C4A 24 0.57 15.1 2.23 96.36
172 INT135436 Gene_expression of Hspa9 31 0.62 14.75 5.2 96.32
173 INT136106 Gene_expression of DNMT3B 30 0.58 8.43 3.7 96.32
174 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34 96.32
175 INT227520 Positive_regulation of Gene_expression of Hspa9 4 0.40 4.16 0.83 96.32
176 INT47662 Localization of CHKB 34 0.81 22.63 5.14 96.28
177 INT119994 Negative_regulation of Trpv2 5 0.58 3.04 1.58 96.24
178 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 96.20
179 INT202195 Negative_regulation of Krt19 2 0.32 2.28 0.3 96.16
180 INT24459 Positive_regulation of PDB1 7 0.46 7 0.5 96.08
181 INT220506 Binding of Cav1 13 0.45 5.46 0.38 96.04
182 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56 96.00
183 INT9547 Regulation of TNNI3 25 0.56 14.22 2.22 96.00
184 INT85297 Positive_regulation of Gene_expression of TNNI3 29 0.50 29.77 1.68 96.00
185 INT35526 Binding of Eef1a2 14 0.34 5.82 1.61 95.92
186 INT312282 Gene_expression of Col9a3 1 0.52 1.16 0 95.76
187 INT23535 Positive_regulation of Localization of CA2 41 0.41 13.52 9.43 95.76
188 INT33517 Gene_expression of TSHR 20 0.71 14.65 1.45 95.64
189 INT232584 Transcription of DMPK 5 0.47 3.41 0.13 95.64
190 INT155200 Protein_catabolism of VCP 1 0.70 1.18 0.06 95.60
191 INT27882 Gene_expression of HSP90B2P 52 0.75 36.51 9.59 95.60
192 INT18391 Positive_regulation of GYPA 41 0.40 16.47 8.69 95.60
193 INT26678 Negative_regulation of Dmpk 11 0.47 3.45 0.26 95.56
194 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 95.52
195 INT20630 Positive_regulation of Gene_expression of CHKB 19 0.47 15.79 1.85 95.52
196 INT303287 Gene_expression of Tardbp 4 0.77 44.78 1.09 95.48
197 INT19947 Negative_regulation of B3GAT2 10 0.57 4.2 7.95 95.48
198 INT5489 Localization of CA2 172 0.80 39.46 33.56 95.36
199 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 95.32
200 INT171959 Binding of Tnfrsf11a 15 0.34 11.03 3.02 95.32
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