D:Muscle Hypotonia

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Disease Term
Synonyms Decreased Muscle Tone, Flaccid Muscle Tone, Flaccidity Muscle, FLACCIDITY MUSCULAR, Floppy Muscle, Floppy Muscles, HYPOMYOTONIA, HYPOTONIA, Hypotonia Muscle, HYPOTONIA MUSCULAR, Hypotonia Neonatal
Documents 310
Hot Single Events 69
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Muscle Hypotonia. They are ordered first by their relevance to Muscle Hypotonia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT349608 Binding of DIO2 and LMOD1 1 0.23 0.41 2.01 98.84
2 INT237354 Binding of DNM2 and Bin1 1 0.40 1.22 0 91.20
3 INT271071 Binding of ACTA1 and Hypism 1 0.00 1.54 0.15 90.88
4 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 80.32
5 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 80.32
6 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 80.12
7 INT317900 Binding of NCAPH2 and MCPH1 1 0.02 0.53 0 63.20
8 INT264679 IGFALS Positive_regulation of CTSC 1 0.02 1.68 0 60.72
9 INT289878 Binding of MMD and SEPN1 1 0.16 1.27 0 49.56
10 INT200063 Binding of MAGED1 and Ngfr 1 0.44 0.45 0 39.44
11 INT200055 Binding of Ngfr and Mageh1 1 0.33 0.45 0 39.44
12 INT200065 Binding of MAGED1 and Ntf3 1 0.32 0.23 0 38.88
13 INT200054 Binding of Ntf3 and Mageh1 1 0.24 0.22 0 38.88
14 INT200057 Binding of Ndn and Ngfr 1 0.43 1.96 0 37.60
15 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 34.32
16 INT200064 Binding of MAGED1 and Mageh1 1 0.30 0.23 0 33.52
17 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0 21.84
18 INT200053 Binding of Nuc and Ngfr 1 0.10 0.3 0 21.84
19 INT200061 Binding of Ngfr and Fez1 1 0.31 0.3 0 21.84
20 INT351391 Binding of Sod2 and Gtf3a 1 0.00 0.18 0.27 21.16
21 INT235594 Binding of LIFR and Rem1 1 0.02 0.36 0 19.24
22 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 15.12
23 INT200060 Binding of Nuc and Ndn 1 0.10 0.29 0 10.40
24 INT200058 Binding of Ndn and Bbs4 1 0.30 0.29 0 9.28
25 INT200056 Binding of Ndn and Fez1 1 0.31 0.28 0 8.80
26 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
27 INT302369 Binding of Arx and Dlx1 1 0.34 0 0.43 5.00
28 INT331966 Binding of DES and SACM1L 1 0.01 1.86 0.36 5.00
29 INT302371 Dlx1 Regulation of Gene_expression of Arx 1 0.28 0 0.35 5.00
30 INT302367 Dlx2 Regulation of Gene_expression of Arx 1 0.59 0.23 0.22 5.00
31 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22 5.00
32 INT302712 Binding of Hprt and Hrh1 1 0.25 1.07 0.2 5.00
33 INT302711 Binding of Hrh1 and Spnb4 1 0.18 1.07 0.2 5.00
34 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19 5.00
35 INT303749 Binding of Chrm3 and Chrm1 Negative_regulation of Gene_expression of Chat 1 0.03 1.12 0.19 5.00
36 INT302372 Arx Negative_regulation of Gene_expression of Calb2 1 0.13 0.05 0.18 5.00
37 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
38 INT303743 Positive_regulation of Binding of Ins1 and Chrm1 1 0.07 1.04 0.15 5.00
39 INT303744 Binding of Chrm3 and Ins1 1 0.04 1.03 0.15 5.00
40 INT303746 Binding of Ins1 and Chrm1 1 0.05 1.03 0.15 5.00
41 INT303745 Positive_regulation of Binding of Chrm3 and Ins1 1 0.05 1.04 0.15 5.00
42 INT303747 Binding of Chrm3 and Chrm1 1 0.03 1.02 0.15 5.00
43 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
44 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
45 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14 5.00
46 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14 5.00
47 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 5.00
48 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12 5.00
49 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12 5.00
50 INT289794 Binding of Comp and Fn1 1 0.07 2.59 0.12 5.00
51 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12 5.00
52 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
53 INT288219 Cigs1 Regulation of Nrgn 1 0.00 0.87 0.1 5.00
54 INT224985 Binding of Ube3a and Snord116 1 0.34 0.45 0.08 5.00
55 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
56 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
57 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
58 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00
59 INT237351 Binding of Mtm1 and Gopc 1 0.19 0.17 0.05 5.00
60 INT214847 Binding of VWF and ANGPTL5 1 0.03 1.16 0.05 5.00
61 INT251944 Binding of GH1 and PRNP 1 0.09 1.14 0.05 5.00
62 INT297850 Snx1 Positive_regulation of Protein_catabolism of P9Ehs1 1 0.01 0.31 0.05 5.00
63 INT224988 Binding of Snord116 and Snurf 1 0.15 0.22 0.04 5.00
64 INT224991 Snord116 Positive_regulation of SNORD108 1 0.37 0.61 0.04 5.00
65 INT224986 Binding of Snrpn and Snord116 1 0.30 0.21 0.04 5.00
66 INT224990 Snord116 Positive_regulation of SNORD107 1 0.38 0.62 0.04 5.00
67 INT224987 Snord116 Positive_regulation of Snord64 1 0.55 0.62 0.04 5.00
68 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03 5.00
69 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
70 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03 5.00
71 INT315034 Ass1 Positive_regulation of Cacna1f 1 0.00 0 0.03 5.00
72 INT272517 Binding of Ccnd1 and Celf1 3 0.08 0.07 0 5.00
73 INT312289 Binding of Col9a1 and Comp 1 0.09 1.38 0 5.00
74 INT311390 Mbnl1 Positive_regulation of Celf1 1 0.26 0.48 0 5.00
75 INT311387 Binding of Celf1 and Mbnl1 1 0.20 0.25 0 5.00
76 INT311405 CCND3 Regulation of Celf1 1 0.41 0.14 0 5.00
77 INT312956 Regulation of Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
78 INT311404 Binding of CDKN2A and Celf1 1 0.32 0.07 0 5.00
79 INT315033 Binding of Calm3 and Vsig2 1 0.00 0 0 5.00
80 INT297848 Binding of Fzd4 and Ndp 1 0.04 1.19 0 5.00
81 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0 5.00
82 INT311389 Positive_regulation of Binding of Celf1 and Eif2s2 1 0.17 0.59 0 5.00
83 INT311381 Phosphorylation of Akt1 Regulation of Celf1 1 0.10 0.14 0 5.00
84 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
85 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0 5.00
86 INT311379 Celf1 Negative_regulation of Mbnl1 1 0.24 0.26 0 5.00
87 INT311384 Binding of Cnbp and Eef2 1 0.07 0.15 0 5.00
88 INT302364 Binding of Arx and Reln 1 0.32 1.25 0 5.00
89 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0 5.00
90 INT311385 Gopc Regulation of Celf1 1 0.04 0.14 0 5.00
91 INT272516 Binding of Celf1 and Tpt1 2 0.05 0.07 0 5.00
92 INT311380 Positive_regulation of Celf1 Negative_regulation of Mbnl1 1 0.26 0.26 0 5.00
93 INT340379 Binding of Rabep1 and Ocrl 1 0.08 0.62 0 5.00
94 INT302370 Binding of Arx and Dcx 1 0.35 1.25 0 5.00
95 INT340380 Binding of Cfl1 and Clcn4-2 1 0.13 0.82 0 5.00
96 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0 5.00
97 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0 5.00
98 INT311393 Binding of Eef2 and Rps17 1 0.02 0.15 0 5.00
99 INT311392 Binding of Cnbp and Pabpc1 1 0.04 0.14 0 5.00
100 INT311397 Binding of Celf1 and Gopc 1 0.04 0.09 0 5.00
101 INT315029 Binding of Calm3 and Cacna1f 1 0.04 0 0 5.00
102 INT297854 Agrp Regulation of Pomc 1 0.24 0 0 5.00
103 INT311378 Binding of Cnbp and Rps17 1 0.06 0.14 0 5.00
104 INT311375 Phosphorylation of Prkca Positive_regulation of Celf1 1 0.04 0.1 0 5.00
105 INT297852 Nanos2 Positive_regulation of Positive_regulation of Gopc 1 0.07 0.1 0 5.00
106 INT297856 Pdk4 Positive_regulation of Positive_regulation of Gopc 1 0.07 0.1 0 5.00
107 INT320848 Binding of Npc1 and Npc2 1 0.39 0 0 5.00
108 INT311402 Binding of Celf1 and Eif2s2 Positive_regulation of Phosphorylation of Celf1 1 0.11 0.22 0 5.00
109 INT312955 Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
110 INT302373 Binding of Arx and Tuba1a 1 0.30 1.26 0 5.00
111 INT297851 Nanos2 Regulation of Stra8 1 0.35 0.6 0 5.00
112 INT312290 Binding of Col9a1 and Matn3 1 0.02 0.65 0 5.00
113 INT297853 Nanos2 Positive_regulation of Positive_regulation of Snord116 1 0.49 0.1 0 5.00
114 INT340378 Binding of Cfl1 and Clcn5 1 0.15 0.82 0 5.00
115 INT192618 Atrx Regulation of Gene_expression of Hba-a1 1 0.08 0.45 0 5.00
116 INT302368 Binding of Arx and Pafah1b1 1 0.27 1.25 0 5.00
117 INT311394 Binding of Celf1 and Eif2s2 1 0.12 1.67 0 5.00
118 INT264678 Binding of SETX and KRT20 1 0.00 2.17 0 5.00
119 INT311391 Binding of Celf1 and Dmpk 1 0.34 0.09 0 5.00
120 INT297849 Pdk4 Positive_regulation of Positive_regulation of Snord116 1 0.50 0.1 0 5.00
121 INT311395 Binding of Esr1 and 20S 1 0.04 0.11 0 5.00
122 INT311383 Mbnl1 Regulation of Insr 1 0.00 0.24 0 5.00
123 INT315035 Binding of NAE1 and Cav1 1 0.01 0.7 0 5.00
124 INT200059 Gtf3a Positive_regulation of Ndn 1 0.06 0.89 0 5.00
125 INT297846 Nanos2 Regulation of Dnmt3l 1 0.34 0.6 0 5.00
126 INT311376 Binding of Ccnd3 and Celf1 1 0.06 0.07 0 5.00
127 INT311386 Celf1 Regulation of Insr 1 0.00 0.24 0 5.00
128 INT311388 Mbnl1 Positive_regulation of Binding of Celf1 1 0.26 0.13 0 5.00
129 INT311377 Binding of Eef2 and Pabpc1 1 0.01 0.15 0 5.00
130 INT311396 Akt1 Regulation of Celf1 1 0.04 0.14 0 5.00
131 INT315031 Binding of Cacna1f and Vsig2 1 0.02 0 0 5.00
132 INT312291 Binding of Comp and Matn3 1 0.06 1.37 0 5.00
133 INT264682 Binding of VAPB and SETX 1 0.28 1.09 0 5.00
134 INT340377 Binding of Clcn4-2 and Clcn5 1 0.35 0.82 0 5.00
135 INT311403 CDKN2A Regulation of Celf1 1 0.41 0.14 0 5.00
136 INT210285 Ccrs1 Regulation of RAI1 1 0.00 0.37 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Muscle Hypotonia. They are ordered first by their pain relevance and then by number of times they were reported in Muscle Hypotonia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT121774 Binding of ACTA1 4 0.47 2.31 0.85 100.00
2 INT95755 Negative_regulation of Acox1 3 0.03 1.9 0.27 99.12
3 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 98.82
4 INT49566 Positive_regulation of LMOD1 16 0.61 5.74 5.92 97.84
5 INT37103 Gene_expression of CHRNE 5 0.67 4.32 0.12 97.64
6 INT220700 Gene_expression of MUSK 3 0.75 6.67 0.07 97.64
7 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62 97.56
8 INT3496 Negative_regulation of HPRT1 7 0.58 25.05 1.92 96.96
9 INT224948 Negative_regulation of Pdia6 3 0.15 2.54 1.67 96.88
10 INT31780 Binding of DIO2 17 0.36 10.07 10 96.84
11 INT1893 Localization of Gh 1041 0.79 340.23 256.58 95.56
12 INT74164 Negative_regulation of UBXN11 14 0.42 6.76 1.4 95.44
13 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 95.28
14 INT74631 Gene_expression of UBXN11 19 0.75 6.11 0.57 94.60
15 INT36893 Negative_regulation of Coq10a 36 0.55 22.24 5.47 94.50
16 INT59119 Positive_regulation of ADCYAP1 9 0.69 4.68 2.48 93.20
17 INT3040 Gene_expression of MIA3 81 0.24 53.61 12.62 93.12
18 INT27554 Regulation of Eln 6 0.52 6.76 0.39 92.72
19 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 91.16
20 INT167847 Positive_regulation of Gene_expression of Chrna7 7 0.49 3.02 1.57 91.00
21 INT235585 Negative_regulation of Negative_regulation of LIFR 1 0.16 0.35 0 90.88
22 INT235588 Negative_regulation of Negative_regulation of ITSN2 1 0.30 0.35 0 90.88
23 INT178458 Negative_regulation of LIFR 13 0.47 8.75 2.48 90.64
24 INT235589 Negative_regulation of ITSN2 1 0.41 4.84 0 90.64
25 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48 89.16
26 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 89.12
27 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56 89.08
28 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 88.84
29 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66 88.60
30 INT1352 Localization of Acot1 728 0.80 73.01 296.01 88.52
31 INT224953 Gene_expression of Snord116 23 0.78 9.86 0.89 88.32
32 INT159620 Gene_expression of TRPM1 7 0.75 7.96 1.65 88.32
33 INT192614 Gene_expression of Atrx 1 0.77 1.75 0 88.28
34 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 88.16
35 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 88.08
36 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48 87.72
37 INT22502 Gene_expression of Hal 21 0.53 9.8 3.32 87.16
38 INT74629 Gene_expression of Mmp7 17 0.55 12.78 7.58 86.72
39 INT86464 Binding of LMOD1 31 0.44 10.23 10.46 86.56
40 INT130599 Negative_regulation of PAICS 4 0.30 2.33 0.7 86.40
41 INT340359 Binding of Clcn5 1 0.48 1.91 0 85.84
42 INT228549 Negative_regulation of Gene_expression of Coq10a 13 0.36 7.36 0.47 85.64
43 INT3439 Localization of Abat 1017 0.78 112.39 727.06 85.20
44 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 85.16
45 INT309244 Transcription of HSPA5 1 0.16 2.75 0.36 84.88
46 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 84.44
47 INT63132 Positive_regulation of Pd 10 0.13 5.86 3.15 84.44
48 INT317913 Gene_expression of SHANK3 1 0.64 2.19 0.13 84.28
49 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54 84.20
50 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 83.68
51 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 83.68
52 INT22557 Gene_expression of BMP1 3 0.59 20.18 4.73 83.44
53 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73 83.36
54 INT105794 Negative_regulation of Aldh5a1 2 0.54 1.55 0.8 83.36
55 INT123773 Positive_regulation of Positive_regulation of Mmp2 2 0.17 1.83 0.75 83.36
56 INT16850 Negative_regulation of Localization of Gabrg1 73 0.51 8.28 47.89 83.24
57 INT6354 Localization of Gabrg1 321 0.74 41.41 186.74 82.84
58 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 82.52
59 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 82.52
60 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 82.52
61 INT224966 Positive_regulation of Gene_expression of Snord116 3 0.50 1.72 0.17 82.32
62 INT289891 Localization of SEPN1 1 0.42 0.88 0 82.32
63 INT92756 Negative_regulation of Binding of LMOD1 4 0.54 3.83 3.08 82.08
64 INT4207 Regulation of Avp 267 0.62 63.72 115.33 81.80
65 INT451 Regulation of Oxt 142 0.62 22.07 69.42 81.80
66 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 81.00
67 INT85378 Binding of Pdss1 6 0.28 3.81 1.35 80.56
68 INT288644 Binding of Pdss2 2 0.25 1.37 0.55 80.28
69 INT49001 Regulation of Gria1 51 0.56 18.28 31.22 80.12
70 INT349609 Regulation of Regulation of LMOD1 1 0.41 0.65 0.63 79.76
71 INT27835 Regulation of Positive_regulation of Ren 10 0.44 2.27 2.38 79.72
72 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 79.36
73 INT49568 Regulation of LMOD1 6 0.43 2.57 5 79.28
74 INT22087 Negative_regulation of DBH 3 0.59 1.45 1.84 79.20
75 INT14562 Negative_regulation of Igfbp1 7 0.26 4.32 1.5 79.04
76 INT2695 Regulation of DBH 5 0.45 1.09 2.48 78.72
77 INT147452 Gene_expression of ADCYAP1 14 0.77 12.54 9.28 78.56
78 INT147453 Positive_regulation of Gene_expression of ADCYAP1 3 0.69 3.49 2.1 78.56
79 INT183556 Gene_expression of SNURF 1 0.47 1.83 0.25 77.76
80 INT2090 Negative_regulation of Gaa 5 0.21 3.43 0.4 77.60
81 INT183537 Gene_expression of SNRPN 16 0.64 5.07 0.28 77.52
82 INT30610 Localization of PCa 35 0.65 13.91 4.25 77.36
83 INT9140 Negative_regulation of PFKM 14 0.59 12.67 3.61 77.28
84 INT47062 Gene_expression of ANTXR1 10 0.66 4.63 1.93 77.28
85 INT227102 Gene_expression of Mtm1 2 0.77 9.58 0.26 76.72
86 INT183555 Gene_expression of SNORD108 1 0.44 1.61 0.25 76.56
87 INT29502 Localization of Mmp2 18 0.79 3.49 4.64 76.20
88 INT95757 Negative_regulation of Gene_expression of UBXN11 1 0.41 1.05 0.21 76.16
89 INT183544 Gene_expression of SNORD64 1 0.11 1.61 0.25 76.04
90 INT1530 Regulation of Gh 382 0.61 115.96 112.47 76.04
91 INT9138 Positive_regulation of Negative_regulation of PFKM 2 0.47 1.32 0.14 76.00
92 INT183536 Gene_expression of SNORD109A 5 0.50 2.7 0.32 75.56
93 INT183551 Gene_expression of SNORD116-1 1 0.56 1.77 0.24 75.56
94 INT183539 Gene_expression of SNORD116@ 1 0.10 1.76 0.24 75.56
95 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 75.52
96 INT224963 Gene_expression of Pdia6 6 0.22 4.51 0.28 75.16
97 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 75.12
98 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 75.12
99 INT95759 Gene_expression of DIO3 5 0.51 2.55 5.28 74.88
100 INT95761 Negative_regulation of DIO3 1 0.25 0.52 0.1 74.88
101 INT315025 Gene_expression of Cacna1s 3 0.48 2.3 0.18 74.64
102 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 74.28
103 INT95760 Negative_regulation of Gene_expression of ACO1 1 0.00 0.93 0.2 74.24
104 INT239149 Positive_regulation of Coq9 4 0.33 2.96 0.37 74.24
105 INT95758 Negative_regulation of ACO1 2 0.51 1.25 0.26 74.24
106 INT95756 Gene_expression of ACO1 3 0.27 2.49 0.1 74.24
107 INT191542 Binding of ABCA3 1 0.22 1.61 0.03 73.92
108 INT183546 Transcription of IL21 1 0.06 0.54 0 73.76
109 INT183523 Transcription of Il21 1 0.52 0.53 0 73.12
110 INT61315 Positive_regulation of Gene_expression of Coq10a 6 0.42 3.29 2.19 73.04
111 INT245751 Gene_expression of COL9A2 4 0.65 1.83 0.04 73.00
112 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 72.96
113 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43 72.60
114 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97 72.36
115 INT14690 Localization of CSF2 124 0.80 85.17 27.26 72.36
116 INT129019 Gene_expression of Ndn 31 0.75 11.09 1.73 72.32
117 INT95752 Negative_regulation of Gene_expression of Hsd17b4 1 0.02 0.89 0.19 72.08
118 INT11529 Negative_regulation of Gene_expression of Acox1 2 0.37 0.96 0.26 72.08
119 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 71.76
120 INT173336 Gene_expression of GLUL 16 0.27 6.74 2.78 70.88
121 INT229110 Positive_regulation of Positive_regulation of DIO2 3 0.26 1.08 2.31 70.84
122 INT29121 Positive_regulation of DIO2 23 0.67 6.13 8.46 70.00
123 INT183545 Negative_regulation of Gene_expression of CISH 1 0.10 1.06 0 69.96
124 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 69.80
125 INT42317 Negative_regulation of Dlat 21 0.43 3.13 4.11 69.56
126 INT51861 Gene_expression of Rdh11 8 0.11 2.26 2.82 69.52
127 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 69.48
128 INT95754 Gene_expression of Hsd17b4 1 0.04 0.44 0.09 69.28
129 INT95753 Negative_regulation of Hsd17b4 1 0.03 0.44 0.09 69.28
130 INT28861 Binding of Gh 61 0.46 25.61 6.38 68.96
131 INT240280 Gene_expression of IGFALS 14 0.42 20.38 0.95 68.96
132 INT129016 Transcription of Ndn 2 0.65 1.42 0.07 68.36
133 INT290576 Positive_regulation of NPTX2 1 0.06 3.32 0.31 68.00
134 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 67.76
135 INT288640 Negative_regulation of Gene_expression of St6galnac2 1 0.03 1.72 0 67.52
136 INT188665 Gene_expression of St6galnac2 5 0.06 3.93 1.08 67.52
137 INT80338 Gene_expression of SPTLC1 10 0.78 4.06 1.09 67.16
138 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 66.88
139 INT11528 Gene_expression of Acox1 3 0.58 2.08 0.28 66.88
140 INT9139 Regulation of Negative_regulation of PFKM 1 0.27 0.77 0.16 66.72
141 INT224975 Gene_expression of Ube3a 5 0.76 7.18 1.69 66.08
142 INT224981 Gene_expression of Snrpn 6 0.70 3 0.07 66.08
143 INT224950 Regulation of Gene_expression of Ube3a 1 0.25 0.68 0.07 66.08
144 INT173693 Localization of Gopc 249 0.65 70.49 38.81 65.68
145 INT224960 Localization of Pdia6 2 0.40 0.54 0.05 65.68
146 INT224951 Negative_regulation of Snord116 4 0.43 2.49 0.04 65.48
147 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 65.32
148 INT71263 Gene_expression of Chrm1 13 0.22 9.56 6.24 65.24
149 INT71267 Negative_regulation of Gene_expression of Chrm1 3 0.17 3.22 2.5 65.24
150 INT172370 Binding of MCPH1 6 0.34 4.75 0.13 63.20
151 INT317916 Binding of NCAPH2 1 0.04 0.53 0 63.20
152 INT224974 Negative_regulation of Gene_expression of Snord116 4 0.59 0.91 0.08 63.12
153 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 62.88
154 INT403 Localization of Trh 241 0.81 28.55 81.45 62.72
155 INT248468 Negative_regulation of Smn1 6 0.39 5.55 0.25 62.64
156 INT277255 Transcription of Satb2 1 0.69 0.46 0 62.40
157 INT133841 Gene_expression of SOX10 18 0.67 9.96 0.8 61.68
158 INT299511 Negative_regulation of Elpt 2 0.07 1.79 0.4 61.12
159 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 60.96
160 INT142341 Positive_regulation of Transcription of Igf1 8 0.49 2.44 1.95 60.44
161 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49 60.44
162 INT18583 Positive_regulation of Gene_expression of Ins1 67 0.50 49.72 8.26 60.44
163 INT14560 Regulation of Igf1 41 0.59 19.59 6.3 60.44
164 INT224980 Regulation of Eef1a1 1 0.01 0.24 0 60.44
165 INT224977 Positive_regulation of Transcription of Ins1 2 0.16 0.58 0 60.44
166 INT210272 Binding of Ccrs1 1 0.01 1.13 0 60.40
167 INT94006 Negative_regulation of Srd5a3 1 0.06 1.17 0 60.00
168 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8 59.44
169 INT200039 Negative_regulation of Ndn 1 0.41 5.89 0.29 59.44
170 INT142344 Transcription of Igf1 22 0.69 7.55 6.77 59.20
171 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 59.20
172 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 59.20
173 INT130072 Transcription of Ins1 12 0.54 6.84 0.62 59.20
174 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 58.88
175 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 58.56
176 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8 58.56
177 INT302338 Gene_expression of Arx 1 0.77 2.8 4.93 58.12
178 INT49723 Localization of GLUL 5 0.27 0.67 2.1 58.00
179 INT3366 Localization of PLEK 44 0.78 15.83 9.55 57.76
180 INT237340 Positive_regulation of Mtm1 1 0.60 1.52 0.14 57.76
181 INT228548 Gene_expression of Coq9 12 0.55 4.93 0.4 57.68
182 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 57.60
183 INT14031 Gene_expression of Npy 107 0.78 36.48 35.4 57.60
184 INT27266 Regulation of Gene_expression of Pomc 41 0.62 6.74 14.59 57.60
185 INT89180 Gene_expression of Agrp 54 0.78 14.29 8.84 57.60
186 INT14030 Regulation of Gene_expression of Npy 7 0.47 5.58 2.49 57.60
187 INT214098 Regulation of Gene_expression of Agrp 2 0.38 1.63 0.08 57.60
188 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 57.48
189 INT224958 Negative_regulation of Transcription of Igf1 5 0.56 1.37 0.81 56.72
190 INT192610 Positive_regulation of Atrx 1 0.50 0.78 0 56.48
191 INT57785 Positive_regulation of SGCB 25 0.69 5.01 1.49 56.16
192 INT16314 Gene_expression of NR0B1 25 0.65 7.99 1.71 55.72
193 INT302342 Localization of Arx 1 0.80 0.94 0.83 55.16
194 INT462 Regulation of Pomc 157 0.62 41.67 67.27 55.08
195 INT15190 Regulation of Npy 17 0.61 5.33 5.84 55.08
196 INT104350 Regulation of Agrp 9 0.52 3.53 0.81 55.08
197 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41 54.52
198 INT255571 Gene_expression of Gk 15 0.26 15.42 0.38 54.36
199 INT133842 Binding of SOX10 3 0.38 5.79 1.02 53.92
200 INT155904 Localization of MMD 9 0.32 3.77 0.49 53.60
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