D:Muscle Wasting Disease

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pChart

Disease Term
Synonyms Muscle Wasting Diseases
Documents 2
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Muscle Wasting Disease. They are ordered first by their relevance to Muscle Wasting Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT273363 SOCS3 Regulation of Protein_catabolism of SOCS1 1 0.02 0 0.07 14.32
2 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06 14.32
3 INT273364 SOCS3 Regulation of SOCS1 1 0.02 0 0.07 12.08
4 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06 12.08
5 INT273373 SOCS3 Regulation of Phosphorylation of STAT3 1 0.42 0.06 0.08 5.00
6 INT273366 IL6 Regulation of TWIST1 1 0.06 0.1 0.07 5.00
7 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07 5.00
8 INT273369 SOCS3 Negative_regulation of JAK1 1 0.03 0 0.07 5.00
9 INT273372 IL6 Regulation of Regulation of TWIST1 1 0.10 0.1 0.07 5.00
10 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Muscle Wasting Disease. They are ordered first by their pain relevance and then by number of times they were reported in Muscle Wasting Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.04
2 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 97.32
3 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 97.32
4 INT122916 Binding of Add3 2 0.31 1.16 0.09 95.32
5 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 93.64
6 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 83.48
7 INT179884 Gene_expression of SOCS3 10 0.67 16.57 1.14 71.92
8 INT144038 Transcription of STAT3 4 0.56 0.99 0.25 65.04
9 INT273407 Transcription of SOCS3 1 0.62 0.17 0.11 57.28
10 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 50.16
11 INT139399 Regulation of Gene_expression of PCNA 14 0.56 6.06 0.43 50.16
12 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 38.64
13 INT169987 Transcription of GOPC 45 0.60 21.88 2.61 30.88
14 INT273400 Protein_catabolism of SOCS1 1 0.05 0 0.06 14.32
15 INT129635 Positive_regulation of SOCS1 3 0.49 0.92 0.49 12.08
16 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
17 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
18 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
19 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
20 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
21 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
22 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 5.00
23 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
24 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 5.00
25 INT61626 Transcription of IL6 73 0.72 42.04 17.86 5.00
26 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 5.00
27 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 5.00
28 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 5.00
29 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96 5.00
30 INT121818 Binding of STAT3 25 0.47 11.16 3.67 5.00
31 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4 5.00
32 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81 5.00
33 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33 5.00
34 INT115193 Positive_regulation of Phosphorylation of STAT3 30 0.64 11.37 2.2 5.00
35 INT48880 Positive_regulation of TWIST1 15 0.59 8.6 1.98 5.00
36 INT68952 Localization of PCNA 17 0.62 5.64 1.78 5.00
37 INT165617 Localization of STAT3 28 0.78 9.04 1.72 5.00
38 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6 5.00
39 INT206136 Positive_regulation of Gene_expression of STAT3 14 0.46 4.3 1.1 5.00
40 INT177615 Gene_expression of PAX7 20 0.65 13.5 1.03 5.00
41 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96 5.00
42 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84 5.00
43 INT188433 Negative_regulation of Binding of IL6 6 0.42 2.03 0.56 5.00
44 INT179887 Positive_regulation of SOCS3 10 0.50 13.06 0.45 5.00
45 INT231524 Localization of PAX7 5 0.56 4.2 0.39 5.00
46 INT90242 Positive_regulation of MYOG 4 0.34 1.46 0.22 5.00
47 INT206166 Negative_regulation of Binding of STAT3 4 0.55 1.13 0.2 5.00
48 INT102354 Localization of TWIST1 3 0.75 0.17 0.15 5.00
49 INT177614 Positive_regulation of PAX7 8 0.54 2.14 0.15 5.00
50 INT186632 Regulation of TWIST1 4 0.37 5.28 0.14 5.00
51 INT90241 Transcription of MYOG 2 0.47 0.17 0.13 5.00
52 INT273395 Positive_regulation of MYF6 1 0.16 0.12 0.09 5.00
53 INT273403 Positive_regulation of Transcription of SOCS3 1 0.40 0.06 0.08 5.00
54 INT273397 Binding of SOCS3 1 0.42 0 0.07 5.00
55 INT273405 Negative_regulation of Binding of SOCS3 1 0.37 0 0.07 5.00
56 INT273396 Positive_regulation of NFAM1 1 0.02 0.06 0.05 5.00
57 INT273406 Positive_regulation of Gene_expression of TWIST1 4 0.57 8.42 0.04 5.00
58 INT273402 Positive_regulation of Localization of PAX7 1 0.37 0.09 0.03 5.00
59 INT273404 Positive_regulation of Localization of PCNA 2 0.36 0.09 0.03 5.00
60 INT149440 Negative_regulation of TWIST1 4 0.41 1.5 0 5.00
61 INT273390 Regulation of Gene_expression of PAX7 1 0.33 0 0 5.00
62 INT273392 Transcription of MYF6 1 0.51 0.07 0 5.00
63 INT273393 Phosphorylation of TWIST1 1 0.16 0.4 0 5.00
64 INT273394 Negative_regulation of Gene_expression of PAX7 1 0.32 0 0 5.00
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