D:Muscle Weakness

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Disease Term
Synonyms Muscle Weaknesses, MUSCULAR WEAKNESS, Muscular Weaknesses, Weakness Muscle, WEAKNESS MUSCULAR, WEAKNESSES MUSCLE, WEAKNESSES MUSCULAR
Documents 1552
Hot Single Events 200
Hot Interactions 17

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Muscle Weakness. They are ordered first by their relevance to Muscle Weakness and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT283539 Binding of Litaf and Mad2l1bp 1 0.00 0.67 0.11 100.00
2 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36 97.32
3 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36 97.32
4 INT3751 Binding of GOT1 and PIK3C2A 1 0.08 0.68 0.12 97.08
5 INT3752 Binding of GOT1 and LDHA 1 0.11 0.68 0.12 97.08
6 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35 95.08
7 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82 94.12
8 INT237354 Binding of DNM2 and Bin1 1 0.40 1.22 0 90.08
9 INT289788 Binding of Comp and Scn8a 1 0.16 1.37 0 88.56
10 INT20259 Sct Positive_regulation of Gast 1 0.01 0.86 0.09 87.68
11 INT28816 Binding of TRPV4 and MND1 1 0.27 0.52 0.1 86.12
12 INT283544 Binding of GARS and Bscl2 1 0.01 1.74 0 84.16
13 INT323654 Igfbp1 Negative_regulation of Binding of Igf1 and Igfbp1 1 0.21 1.14 0.29 83.08
14 INT323653 Binding of Igf1 and Igfbp1 1 0.20 1.14 0.29 83.08
15 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27 82.44
16 INT283199 Binding of DMD and PTPRC 1 0.01 0.82 0 82.00
17 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 81.28
18 INT120870 Binding of Wnk1 and Sptlc1 1 0.14 1.24 0.56 73.84
19 INT69709 NPL Positive_regulation of Localization of POMC 2 0.36 1.22 1.51 72.68
20 INT205589 Binding of PPT2 and COQ2 1 0.04 1.02 0.07 72.24
21 INT312628 Agrn Positive_regulation of Lrp4 1 0.22 0.66 0 68.52
22 INT312629 Agrn Positive_regulation of Musk 1 0.76 1.03 0 68.52
23 INT312630 Agrn Positive_regulation of Ldlr 1 0.14 0.66 0 68.52
24 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31 66.72
25 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11 65.08
26 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 63.36
27 INT36328 Binding of AMPD1 and Hmgcl 1 0.01 1.02 0 56.00
28 INT335742 Binding of PDB1 and Dpyd 1 0.02 1.75 0.09 55.28
29 INT335743 Binding of PDB1 and Salpa1 1 0.01 1.66 0.09 54.92
30 INT312956 Regulation of Binding of MOCS1 and MTTP 1 0.00 0.21 0 53.00
31 INT312955 Binding of MOCS1 and MTTP 1 0.00 0.21 0 53.00
32 INT289878 Binding of MMD and SEPN1 1 0.16 1.27 0 51.12
33 INT312645 Binding of DNAJA3 and Musk 1 0.08 0.96 0.07 49.16
34 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 47.76
35 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0 46.56
36 INT312642 DNAJA3 Positive_regulation of Musk 1 0.08 0.37 0 44.84
37 INT312634 Dok7 Positive_regulation of Musk 1 0.68 0.37 0 44.84
38 INT264134 Binding of IFNA1 and Tlr4 1 0.01 1.5 0.22 36.60
39 INT271071 Binding of ACTA1 and Hypism 1 0.00 1.54 0.15 35.68
40 INT289794 Binding of Comp and Fn1 1 0.07 2.59 0.12 29.44
41 INT352627 Binding of IGHG3 and MAN2A1 1 0.00 1.48 0 28.44
42 INT312290 Binding of Col9a1 and Matn3 1 0.02 0.65 0 27.72
43 INT312289 Binding of Col9a1 and Comp 1 0.09 1.38 0 27.60
44 INT339272 VDR Positive_regulation of Gene_expression of KRT20 1 0.00 0.07 0.05 27.52
45 INT312291 Binding of Comp and Matn3 1 0.06 1.37 0 26.16
46 INT101591 Binding of RAC1 and RAC3 1 0.13 0.52 0 25.00
47 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12 23.84
48 INT215683 P2ry2 Positive_regulation of Gene_expression of Il6 1 0.02 0.76 0.29 18.48
49 INT283543 Binding of GARS and Setx 1 0.01 3.71 0 14.56
50 INT283533 Binding of GARS and SPG19 1 0.00 1.72 0 14.56
51 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 13.28
52 INT283542 Binding of SPG19 and Setx 1 0.06 3.69 0 13.28
53 INT312637 Negative_regulation of Binding of Musk and Dok7 1 0.42 1.03 0 12.00
54 INT312635 Binding of Musk and Dok7 1 0.47 3.41 0 12.00
55 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
56 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 5.00
57 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78 5.00
58 INT231968 Binding of Cpn1 and Rvm 1 0.11 1.57 2.45 5.00
59 INT231970 Binding of Cpn1 and Pag1 1 0.07 1.56 2.44 5.00
60 INT231971 Binding of Cpn1 and Shbdp1 1 0.04 1.39 2.26 5.00
61 INT231967 Binding of Psmd1 and Cpn1 1 0.06 1.39 2.25 5.00
62 INT231969 Binding of Cfp and Cpn1 1 0.05 1.38 2.25 5.00
63 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
64 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
65 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
66 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
67 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00
68 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85 5.00
69 INT351322 Nts Regulation of Localization of Napa 1 0.01 0.56 0.77 5.00
70 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77 5.00
71 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73 5.00
72 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
73 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 5.00
74 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67 5.00
75 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67 5.00
76 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
77 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64 5.00
78 INT339794 Sstr2 Positive_regulation of Gene_expression of Sstr5 1 0.08 0.25 0.64 5.00
79 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 5.00
80 INT254199 Il10 Positive_regulation of Gene_expression of Socs3 2 0.06 0.75 0.63 5.00
81 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61 5.00
82 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54 5.00
83 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
84 INT27730 Binding of ALB and Shbg 2 0.01 0.44 0.5 5.00
85 INT339275 Il6 Regulation of KRT20 1 0.00 3.11 0.49 5.00
86 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48 5.00
87 INT264136 IFNA1 Positive_regulation of Socs3 1 0.01 0.38 0.46 5.00
88 INT264137 IFNA1 Positive_regulation of Socs1 1 0.01 0.38 0.46 5.00
89 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44 5.00
90 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43 5.00
91 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42 5.00
92 INT299040 Binding of COL7A1 and SPARC 1 0.02 0.7 0.42 5.00
93 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 5.00
94 INT342181 Binding of Igfals and Ros1 1 0.01 0.76 0.41 5.00
95 INT264135 Socs1 Positive_regulation of Protein_catabolism of TOLLIP 1 0.00 0.33 0.41 5.00
96 INT285746 IL6 Regulation of Localization of PRL 1 0.08 1.51 0.39 5.00
97 INT285749 IL6 Positive_regulation of Localization of PRL 1 0.08 1.51 0.39 5.00
98 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39 5.00
99 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39 5.00
100 INT285750 IL1B Positive_regulation of Localization of PRL 1 0.05 1.51 0.39 5.00
101 INT285744 IL1B Regulation of Localization of PRL 1 0.05 1.51 0.39 5.00
102 INT285571 Binding of IL8 and Il17a 1 0.04 1.03 0.38 5.00
103 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37 5.00
104 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 5.00
105 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 5.00
106 INT272363 Binding of Adar and Adarb1 3 0.26 0.76 0.36 5.00
107 INT331966 Binding of DES and SACM1L 1 0.01 1.86 0.36 5.00
108 INT285557 Eae2 Positive_regulation of Cia1 1 0.02 1.85 0.36 5.00
109 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35 5.00
110 INT285465 IL7 Positive_regulation of TNF 1 0.04 0.67 0.35 5.00
111 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34 5.00
112 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33 5.00
113 INT285558 Binding of Il11ra1 and Il27 1 0.05 1.1 0.33 5.00
114 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33 5.00
115 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 5.00
116 INT326089 Gopc Positive_regulation of Mmp9 1 0.03 0.63 0.33 5.00
117 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33 5.00
118 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31 5.00
119 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31 5.00
120 INT285748 PRL Positive_regulation of Positive_regulation of C6orf25 1 0.01 1.01 0.31 5.00
121 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
122 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29 5.00
123 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29 5.00
124 INT177476 Gnrhr Positive_regulation of Localization of Igf1 1 0.05 1.01 0.28 5.00
125 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28 5.00
126 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28 5.00
127 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 0.22 0.8 0.26 5.00
128 INT326094 Akt1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.49 0.24 5.00
129 INT326092 Gene_expression of Akt1 Negative_regulation of Gopc 1 0.03 0.55 0.24 5.00
130 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23 5.00
131 INT326093 Akt1 Positive_regulation of Gopc 1 0.03 0.43 0.23 5.00
132 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22 5.00
133 INT333762 Positive_regulation of thd Positive_regulation of Eae1 1 0.00 1.6 0.22 5.00
134 INT333758 Hand1 Positive_regulation of Eae1 1 0.05 1.6 0.22 5.00
135 INT177477 Crh Positive_regulation of Crh Regulation of POMC 1 0.02 0.86 0.22 5.00
136 INT285745 IL31RA Positive_regulation of Gene_expression of MPL 1 0.19 1.04 0.22 5.00
137 INT333760 thd Positive_regulation of Eae1 1 0.00 1.6 0.22 5.00
138 INT177479 Negative_regulation of Crh Regulation of POMC 1 0.05 0.84 0.21 5.00
139 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2 5.00
140 INT264298 NOL3 Negative_regulation of CRP 1 0.39 0.49 0.2 5.00
141 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19 5.00
142 INT301782 Binding of Dmd and Utrn 1 0.24 0.15 0.18 5.00
143 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17 5.00
144 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17 5.00
145 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17 5.00
146 INT301784 Binding of Dmd and Sntb1 1 0.05 0.36 0.16 5.00
147 INT326097 WAS Regulation of Gopc 1 0.01 0.55 0.16 5.00
148 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
149 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15 5.00
150 INT316769 Binding of H2-K1 and Hspa9 1 0.08 1.02 0.15 5.00
151 INT177480 Positive_regulation of Crh Positive_regulation of Regulation of POMC 1 0.06 0.46 0.14 5.00
152 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14 5.00
153 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14 5.00
154 INT329847 PPARA Regulation of Gene_expression of CREB3L3 1 0.17 0.84 0.13 5.00
155 INT333761 Il27 Positive_regulation of Il10 1 0.16 0.58 0.13 5.00
156 INT333764 Il6 Regulation of Gene_expression of Il6ra 1 0.02 0.52 0.12 5.00
157 INT289790 Binding of Col7a1 and Comp 1 0.14 1.2 0.12 5.00
158 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00
159 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12 5.00
160 INT301783 Binding of Dtna and Sntb1 1 0.01 0.05 0.12 5.00
161 INT333765 Positive_regulation of Vdr Regulation of Gene_expression of Ccr6 1 0.21 0.48 0.12 5.00
162 INT312631 Binding of Musk and Agrn 1 0.40 0.63 0.12 5.00
163 INT333759 Il6 Positive_regulation of Il27 1 0.09 0.68 0.12 5.00
164 INT301788 Binding of Dmd and Dtna 1 0.09 0.05 0.12 5.00
165 INT287130 Positive_regulation of Binding of NT5E and Comt 1 0.04 0 0.12 5.00
166 INT301789 Binding of Sntb1 and Utrn 1 0.03 0.05 0.12 5.00
167 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11 5.00
168 INT304813 Binding of MNX1 and RT1-CE1 1 0.00 0.34 0.1 5.00
169 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1 5.00
170 INT316543 GH1 Regulation of Gene_expression of IGF1 1 0.03 1.32 0.09 5.00
171 INT316552 Binding of SST and Sst1 1 0.03 0.53 0.09 5.00
172 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
173 INT272365 Gene_expression of Adarb1 Positive_regulation of Gene_expression of GRIA1 1 0.00 0.26 0.09 5.00
174 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09 5.00
175 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
176 INT307665 Binding of Mpz and Pmp22 1 0.34 0.39 0.08 5.00
177 INT303337 Binding of SOD1 and Igfals 1 0.06 1.27 0.08 5.00
178 INT307666 Binding of Pmp22 and Gjb1 1 0.31 0.38 0.08 5.00
179 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08 5.00
180 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
181 INT307663 Binding of Pmp22 and Egr2 1 0.33 0.39 0.08 5.00
182 INT307664 Binding of Pmp22 and LOC689781 1 0.03 0.39 0.08 5.00
183 INT215767 Binding of P2ry1 and Ca2 1 0.02 0.2 0.08 5.00
184 INT329897 PPARA Regulation of Cpt2 1 0.09 0.05 0.07 5.00
185 INT356379 DMD Positive_regulation of Negative_regulation of Utrn 1 0.54 0.84 0.07 5.00
186 INT196592 Binding of CFD and GHRH 1 0.02 1.88 0.07 5.00
187 INT264300 CTSK Positive_regulation of CYP27A1 1 0.03 0.69 0.07 5.00
188 INT215693 Trib3 Regulation of Gene_expression of Ccnd1 1 0.00 0.09 0.07 5.00
189 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 5.00
190 INT250153 Binding of PRNP and IKBKG 1 0.09 2.83 0.06 5.00
191 INT312636 Negative_regulation of Binding of Musk and Lrp4 1 0.21 0.32 0.06 5.00
192 INT312639 Binding of Musk and Lrp4 1 0.23 0.91 0.06 5.00
193 INT250150 Binding of IKBKG and SACM1L 1 0.00 2.78 0.06 5.00
194 INT312632 Binding of Agrn and Lrp4 1 0.17 0.32 0.06 5.00
195 INT312647 Binding of Agrn and SYCP3 1 0.39 0.32 0.06 5.00
196 INT312627 Negative_regulation of Binding of Musk and Agrn 1 0.46 0.32 0.06 5.00
197 INT237351 Binding of Mtm1 and Gopc 1 0.19 0.17 0.05 5.00
198 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05 5.00
199 INT287222 Cytip Regulation of Transcription of Insig1 1 0.02 0.56 0.05 5.00
200 INT193454 Dbh Negative_regulation of Negative_regulation of Ndufaf1 1 0.02 1.22 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Muscle Weakness. They are ordered first by their pain relevance and then by number of times they were reported in Muscle Weakness. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT47030 Negative_regulation of ARMC9 22 0.38 13.08 0.47 100.00
2 INT264054 Negative_regulation of Negative_regulation of Bche 6 0.41 2.49 0.04 100.00
3 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.96
4 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 99.96
5 INT58571 Positive_regulation of ALDOB 6 0.49 5.63 0.53 99.96
6 INT145009 Positive_regulation of Negative_regulation of VDR 2 0.41 1.18 0.25 99.96
7 INT184306 Localization of Comp 2 0.69 5.1 0.12 99.92
8 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 99.90
9 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 99.90
10 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49 99.90
11 INT27627 Binding of Rac1 41 0.41 22.88 13.68 99.84
12 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13 99.84
13 INT281418 Regulation of Negative_regulation of Ache 2 0.43 1.15 0.07 99.80
14 INT64700 Binding of Nf1 14 0.45 15.24 2.29 99.72
15 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16 99.68
16 INT91285 Negative_regulation of P2rx2 29 0.57 12.74 15.48 99.68
17 INT105304 Negative_regulation of Gene_expression of P2rx2 11 0.28 11.07 9.53 99.68
18 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 99.64
19 INT289780 Positive_regulation of Localization of Dnajc1 1 0.08 0.84 0 99.60
20 INT264629 Localization of Rac1 8 0.72 5.7 0.79 99.60
21 INT16184 Negative_regulation of CHKB 20 0.53 10.61 1.42 99.52
22 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 99.48
23 INT67135 Binding of Gc 5 0.10 3.2 0.94 99.48
24 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 99.46
25 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 99.44
26 INT82719 Positive_regulation of ASF1A 2 0.08 9.55 3 99.40
27 INT45510 Binding of Scn8a 4 0.31 3.89 0.25 99.40
28 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 99.36
29 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 99.36
30 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68 99.32
31 INT112430 Negative_regulation of P2rx4 9 0.57 8.4 6.63 99.32
32 INT215594 Negative_regulation of Gene_expression of P2rx4 7 0.48 6.46 5.22 99.32
33 INT142340 Positive_regulation of Chkb 3 0.47 6.44 0.38 99.28
34 INT9664 Binding of LBP 127 0.48 94.9 63.42 99.28
35 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 99.16
36 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 99.16
37 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.08
38 INT37107 Negative_regulation of CHRNE 4 0.43 2.25 0.87 99.08
39 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 99.04
40 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 99.04
41 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85 99.04
42 INT158837 Binding of POLG 4 0.37 4.69 0.44 99.04
43 INT289776 Localization of Dnajc1 1 0.11 1.86 0.08 99.02
44 INT111263 Gene_expression of Gnb5 8 0.75 8.51 3 98.96
45 INT335731 Gene_expression of Vcp 1 0.73 12.21 0.18 98.86
46 INT312285 Positive_regulation of Positive_regulation of Chkb 1 0.24 1.02 0 98.80
47 INT1939 Localization of Cys1 6 0.73 5.9 0.64 98.72
48 INT240719 Negative_regulation of ATP6 5 0.08 2.33 0.04 98.64
49 INT47992 Gene_expression of Scn8a 14 0.78 4.15 3.83 98.64
50 INT312282 Gene_expression of Col9a3 1 0.52 1.16 0 98.64
51 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52 98.60
52 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 98.48
53 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 98.48
54 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 98.48
55 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 98.48
56 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1 98.48
57 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 98.28
58 INT42497 Regulation of Negative_regulation of POMC 4 0.44 0.63 1.99 98.28
59 INT108913 Positive_regulation of HAL 10 0.28 5.71 1.59 98.24
60 INT73226 Regulation of Vmo1 2 0.18 2.19 0.68 98.22
61 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 98.16
62 INT45039 Positive_regulation of Phex 1 0.29 0.41 0.16 98.04
63 INT105021 Binding of GOPC 187 0.40 60.39 20.38 98.04
64 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 97.96
65 INT205401 Gene_expression of Chkb 32 0.51 13.99 0.77 97.94
66 INT97777 Positive_regulation of CNBP 7 0.37 9.85 1.09 97.92
67 INT22804 Positive_regulation of ALDOC 8 0.41 8.07 1.02 97.76
68 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 97.76
69 INT5793 Binding of CTS 110 0.48 63.91 40.62 97.76
70 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99 97.64
71 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45 97.60
72 INT41627 Gene_expression of Nqo1 33 0.65 4.58 10.48 97.60
73 INT142420 Negative_regulation of Gene_expression of Nqo1 2 0.41 0.26 0.15 97.60
74 INT237347 Binding of Bin1 1 0.36 0.44 0.03 97.60
75 INT72870 Negative_regulation of SPTLC2 7 0.57 1.82 1.73 97.52
76 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67 97.52
77 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 97.52
78 INT237340 Positive_regulation of Mtm1 1 0.60 1.52 0.14 97.40
79 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 97.40
80 INT3343 Regulation of PTH 24 0.62 11.18 1.62 97.24
81 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 97.20
82 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 97.16
83 INT184305 Gene_expression of Comp 53 0.77 31.66 2.2 96.96
84 INT335733 Positive_regulation of Tardbp 8 0.69 28.41 0.41 96.88
85 INT121338 Binding of MTUS1 5 0.07 3.41 0.16 96.88
86 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 96.84
87 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 96.72
88 INT155201 Gene_expression of VCP 4 0.75 8.25 0.31 96.60
89 INT335729 Gene_expression of Vmn1r155 1 0.01 2.54 0 96.60
90 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 96.60
91 INT335732 Positive_regulation of Gene_expression of Vcp 1 0.57 0.87 0 96.60
92 INT49082 Gene_expression of MPZ 15 0.65 31.26 2.24 96.48
93 INT38283 Positive_regulation of Cebpg 2 0.04 1.96 0.69 96.44
94 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 96.40
95 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 96.40
96 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 96.40
97 INT16869 Positive_regulation of Prl 24 0.70 15.7 7.63 96.36
98 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 96.32
99 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 96.08
100 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 95.92
101 INT60645 Regulation of COL4A4 1 0.22 0.51 0.27 95.76
102 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 95.68
103 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 95.68
104 INT216105 Regulation of Gene_expression of Dmd 7 0.36 2.55 0.41 95.52
105 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63 95.44
106 INT166813 Regulation of Asph 1 0.09 0.37 0.1 95.44
107 INT166811 Regulation of Casq1 3 0.04 1.18 0.1 95.44
108 INT250744 Positive_regulation of BCKDHB 1 0.03 1.01 0.07 95.44
109 INT277403 Positive_regulation of Positive_regulation of KIF1B 1 0.42 0.85 0 95.44
110 INT28151 Positive_regulation of CTs 55 0.61 35.09 20.14 95.32
111 INT95695 Transcription of Chrnb1 2 0.19 0.8 0.47 95.24
112 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 95.12
113 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 95.12
114 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 95.12
115 INT227102 Gene_expression of Mtm1 2 0.77 9.58 0.26 95.04
116 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 95.04
117 INT3491 Negative_regulation of CPT2 8 0.57 4.32 0.62 95.00
118 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 95.00
119 INT251238 Gene_expression of Lvs 35 0.32 29.41 1.59 94.96
120 INT95924 Negative_regulation of Bczr1 1 0.00 1.5 0.47 94.96
121 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 94.92
122 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34 94.92
123 INT335738 Positive_regulation of VCP 1 0.06 1.88 0.06 94.76
124 INT69221 Negative_regulation of Sod1 14 0.56 10.57 1.83 94.68
125 INT112728 Negative_regulation of COQ7 1 0.50 4.8 0.89 94.64
126 INT443 Localization of POMC 1020 0.81 284.52 443.17 94.60
127 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 94.60
128 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02 94.60
129 INT214945 Regulation of Neu3 11 0.01 1.65 0.51 94.56
130 INT237342 Regulation of Binding of Neu3 1 0.00 0.43 0.03 94.56
131 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 94.48
132 INT231964 Binding of Cpn1 1 0.25 5.28 6.63 94.48
133 INT111199 Gene_expression of Acly 11 0.16 5.65 0.78 94.48
134 INT60440 Localization of PSMD1 10 0.74 3.94 2.57 94.40
135 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49 94.36
136 INT35292 Negative_regulation of C5 7 0.43 5.3 0.86 94.28
137 INT127003 Binding of Neu3 7 0.02 1.57 1.05 94.16
138 INT16728 Gene_expression of SPTA1 2 0.16 0.31 0.23 94.04
139 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 94.00
140 INT119994 Negative_regulation of Trpv2 5 0.58 3.04 1.58 93.96
141 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04 93.92
142 INT152525 Negative_regulation of Eef1a1 1 0.07 0.91 0.55 93.92
143 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 93.84
144 INT82308 Negative_regulation of HADHA 2 0.38 1.52 0.91 93.84
145 INT6852 Localization of TNF 883 0.81 705.95 270.84 93.76
146 INT277406 Positive_regulation of KIF1B 1 0.42 0.84 0 93.72
147 INT738 Regulation of POMC 459 0.62 111.19 243.74 93.60
148 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32 93.56
149 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 93.48
150 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 93.20
151 INT354726 Binding of Tymp 1 0.30 1.08 0.23 93.20
152 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75 93.12
153 INT125729 Positive_regulation of MAMLD1 1 0.49 0.72 0.14 93.08
154 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 93.00
155 INT96364 Positive_regulation of Ugcg 5 0.36 1.86 1.82 92.80
156 INT272511 Positive_regulation of DMPK 8 0.54 6.85 0.72 92.80
157 INT92839 Regulation of P2rx2 36 0.45 13.19 15.38 92.76
158 INT105306 Regulation of Gene_expression of P2rx2 7 0.21 6.92 5.22 92.76
159 INT215722 Regulation of P2rx4 2 0.20 0.89 0.6 92.76
160 INT125727 Positive_regulation of FGF23 5 0.69 4.04 0.53 92.72
161 INT248419 Negative_regulation of Tph2 11 0.59 6.32 2.59 92.60
162 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 92.56
163 INT331973 Gene_expression of MYOT 4 0.64 3.83 0.4 92.56
164 INT94347 Gene_expression of DYSF 4 0.75 3.25 0.41 92.56
165 INT201259 Negative_regulation of RAB7A 2 0.41 2.45 0.54 92.40
166 INT143328 Binding of THAS 2 0.26 1.21 0.25 92.40
167 INT334064 Negative_regulation of PADI1 1 0.38 1.72 0.14 92.28
168 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 92.24
169 INT31412 Negative_regulation of Positive_regulation of Ins1 10 0.40 7.14 2.82 92.24
170 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 92.12
171 INT151032 Localization of Igf1 49 0.76 26.32 5.71 91.92
172 INT125728 Localization of MAMLD1 1 0.68 1.44 0.28 91.76
173 INT125726 Localization of CANT1 1 0.68 0.72 0.14 91.76
174 INT83611 Negative_regulation of Gene_expression of Cpox 55 0.29 31.09 11.5 91.60
175 INT197721 Positive_regulation of ARMC9 36 0.35 20.08 1.03 91.56
176 INT161500 Gene_expression of PC 42 0.67 9.02 2.2 91.56
177 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 91.48
178 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 91.44
179 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91 91.44
180 INT756 Gene_expression of C3 138 0.75 100.6 19.2 91.40
181 INT146917 Localization of Slmap 4 0.80 1.56 0.42 91.36
182 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 91.36
183 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 91.32
184 INT238840 Gene_expression of Pygm 2 0.65 1.9 0 91.28
185 INT312978 Negative_regulation of Pygm 1 0.42 0.95 0 91.28
186 INT106510 Gene_expression of Ptges 70 0.75 36.18 9.75 91.28
187 INT312974 Gene_expression of CPT2 1 0.47 0.94 0 91.00
188 INT65261 Regulation of Col7a1 18 0.55 8.7 1.33 91.00
189 INT17110 Gene_expression of PSMD1 60 0.65 19.57 4.69 90.96
190 INT251831 Positive_regulation of C10orf2 1 0.50 1.23 0.08 90.96
191 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 90.92
192 INT6507 Binding of C5 23 0.48 15.35 3.91 90.80
193 INT23376 Localization of NPL 7 0.47 2.59 3.29 90.76
194 INT303287 Gene_expression of Tardbp 4 0.77 44.78 1.09 90.72
195 INT264110 Regulation of Chrnb1 1 0.03 0.82 0.31 90.52
196 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 90.44
197 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 90.36
198 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 90.36
199 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 90.36
200 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 90.32
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