D:Muscular Atrophy

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pChart

Disease Term
Synonyms Atrophies Muscle, Atrophies Muscular, Atrophies Neurogenic Muscular, Atrophies Neurotrophic Muscular, ATROPHY MUSCLE, Atrophy Muscular, Atrophy Neurogenic Muscular, Atrophy Neurotrophic Muscular, MUSCLE ATROPHIES, Muscle Atrophy, Muscular Atrophies
Documents 606
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Muscular Atrophy. They are ordered first by their relevance to Muscular Atrophy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT340555 Igf1 Positive_regulation of Mapk1 1 0.24 0.65 0.09 96.72
2 INT340562 Mstn Positive_regulation of Mapk1 1 0.16 1.16 0.17 95.92
3 INT276887 MTOR Regulation of Ppargc1a 1 0.23 0.33 0 95.70
4 INT276868 MTOR Regulation of Gene_expression of MTUS1 1 0.01 0.33 0 95.70
5 INT231116 Ros1 Positive_regulation of Protein_catabolism of Psmb8 1 0.00 1.14 0 95.52
6 INT218300 Gtf3a Positive_regulation of Gene_expression of Fbxo32 1 0.00 0.09 0 93.12
7 INT340567 Jun Positive_regulation of Gene_expression of Ccnd1 1 0.05 0.27 0.07 91.28
8 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11 90.36
9 INT303399 Binding of Jag1 and Myh3 1 0.50 0.85 0 90.20
10 INT303388 Binding of Laptm5 and Rnf123 1 0.00 0.18 0 87.76
11 INT162437 Binding of Igf1 and Igfals 1 0.10 1.45 0 87.04
12 INT226210 Akt1 Regulation of Mul1 1 0.04 0.6 0.1 86.24
13 INT267216 Binding of Cryab and Hspb8 1 0.36 9.29 0 82.28
14 INT339260 EPAS1 Positive_regulation of VEGFA 1 0.19 3.67 0 80.60
15 INT303389 Binding of Jag1 and Cul5 1 0.20 0.29 0.04 77.84
16 INT303393 Binding of Jag1 and Tceb2 1 0.03 0.29 0.04 77.84
17 INT340556 Binding of Akt1 and Myh1 1 0.04 0.27 0.04 76.80
18 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 76.56
19 INT340558 Gene_expression of Fst Positive_regulation of Akt1 1 0.09 0.41 0.03 74.80
20 INT340568 Fgf1 Positive_regulation of Mapk1 1 0.06 1.02 0.04 74.44
21 INT340566 Binding of Mstn and Mapk1 1 0.12 0.5 0 70.84
22 INT162436 Binding of Igfals and Tardbp 1 0.16 2.68 0 70.56
23 INT162435 Binding of Igfals and Rapsn 1 0.19 1.34 0 70.56
24 INT339262 EPAS1 Positive_regulation of Gene_expression of VEGFA 1 0.14 0.23 0 64.40
25 INT22926 Binding of CD79A and IGL@ 1 0.01 0.59 0.09 63.52
26 INT327052 Gene_expression of Akt1 Positive_regulation of Gene_expression of Myod1 1 0.19 0.18 0 61.36
27 INT327053 Gene_expression of Akt1 Positive_regulation of Gene_expression of Txlnb 1 0.04 0.18 0 60.24
28 INT303394 Binding of Myh3 and Mul1 1 0.04 0.38 0 59.36
29 INT272197 Binding of CAPN3 and DYSF 1 0.42 0.38 0 57.92
30 INT340553 Pik3r1 Regulation of Gene_expression of Fbxo32 1 0.04 0.52 0.07 52.84
31 INT340564 Akt1 Regulation of Gene_expression of Fbxo32 1 0.05 0.52 0.07 52.84
32 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22 48.04
33 INT326573 Zic2 Positive_regulation of Localization of Hsf1 1 0.01 0.95 0.07 45.40
34 INT114883 Akt1 Regulation of Pik3r1 2 0.16 0.65 0.92 42.72
35 INT340552 Binding of Mapk1 and Mapk14 1 0.07 0.27 0.03 39.20
36 INT288163 Binding of gr and Igh-Dex 1 0.03 0.18 0.27 36.00
37 INT226190 Binding of Igf1 and Positive_regulation of Pik3cb 1 0.17 1.04 0 33.24
38 INT226207 Binding of Ins1 and Positive_regulation of Pik3cb 1 0.01 2.08 0 33.24
39 INT226206 Gtf3a Positive_regulation of Akt1 1 0.00 1.02 0 31.56
40 INT226193 Gtf3a Positive_regulation of Pik3cb 1 0.00 1.02 0 31.56
41 INT303390 Binding of Jag1 and Myo1f 1 0.07 0 0 28.24
42 INT267215 Binding of Cryab and Hspb1 1 0.25 7.19 0 27.76
43 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12 22.08
44 INT340554 Myod1 Positive_regulation of Negative_regulation of Mapk1 1 0.28 0.25 0 14.64
45 INT340551 Myod1 Positive_regulation of Mapk1 1 0.19 0.25 0 14.64
46 INT340559 Myod1 Positive_regulation of Myog 1 0.12 0.25 0 14.64
47 INT340560 Myog Positive_regulation of Mapk1 1 0.07 0.25 0 14.28
48 INT340557 Myog Positive_regulation of Negative_regulation of Mapk1 1 0.16 0.25 0 14.28
49 INT311384 Binding of Cnbp and Eef2 1 0.07 0.15 0 11.52
50 INT311393 Binding of Eef2 and Rps17 1 0.02 0.15 0 11.52
51 INT311377 Binding of Eef2 and Pabpc1 1 0.01 0.15 0 11.52
52 INT311392 Binding of Cnbp and Pabpc1 1 0.04 0.14 0 8.32
53 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2 8.12
54 INT311378 Binding of Cnbp and Rps17 1 0.06 0.14 0 5.84
55 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
56 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
57 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
58 INT280949 Binding of Fst and Inhbe 3 0.01 2.51 1.15 5.00
59 INT183176 Binding of FGFR2 and NUDT6 1 0.05 1.07 0.84 5.00
60 INT183177 Binding of FGFR3 and NUDT6 1 0.06 1.08 0.84 5.00
61 INT183175 Binding of FGF2 and NUDT6 1 0.07 1.07 0.84 5.00
62 INT180496 Binding of CTS and PDXK 1 0.04 0.69 0.77 5.00
63 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
64 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
65 INT27730 Binding of ALB and Shbg 2 0.01 0.44 0.5 5.00
66 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
67 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
68 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 5.00
69 INT342181 Binding of Igfals and Ros1 1 0.01 0.76 0.41 5.00
70 INT288162 Igh-Dex Positive_regulation of Gopc 1 0.02 0.63 0.41 5.00
71 INT272951 Binding of TNF and Igf1 1 0.14 1.48 0.36 5.00
72 INT288168 Binding of Jun and Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.01 0.52 0.36 5.00
73 INT272953 Negative_regulation of Binding of TNF and Igf1 1 0.16 1.48 0.36 5.00
74 INT272363 Binding of Adar and Adarb1 3 0.26 0.76 0.36 5.00
75 INT228922 Binding of Prf1 and RCT 1 0.08 0.36 0.36 5.00
76 INT272952 Igf1 Positive_regulation of Localization of TNF 1 0.19 1.53 0.35 5.00
77 INT288164 Jun Regulation of Gene_expression of Mmp13 1 0.02 0.41 0.35 5.00
78 INT288167 Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.06 0.46 0.35 5.00
79 INT203395 Edn1 Positive_regulation of Vegfa 1 0.06 1.59 0.35 5.00
80 INT262307 CAPNS1 Regulation of TAF9 1 0.04 1.23 0.33 5.00
81 INT288165 Binding of Jun and Ugcg 1 0.02 0.45 0.32 5.00
82 INT288166 Binding of gr and Ugcg 1 0.07 0.45 0.31 5.00
83 INT228530 Gopc Positive_regulation of Gene_expression of Nos2 2 0.22 0.67 0.28 5.00
84 INT229702 Binding of Ppara and Ros1 1 0.01 1.05 0.23 5.00
85 INT180600 MAOB Positive_regulation of TAC1 1 0.00 0.13 0.22 5.00
86 INT258456 PYCARD Negative_regulation of Localization of Tms 1 0.02 0.05 0.21 5.00
87 INT258455 Tms Negative_regulation of Localization of PYCARD 1 0.02 0.05 0.21 5.00
88 INT226209 Pik3cb Positive_regulation of Phosphorylation of Akt1 1 0.10 1.16 0.17 5.00
89 INT215901 Ins1 Positive_regulation of Igfals 1 0.02 0.81 0.15 5.00
90 INT215902 Igfbp2 Positive_regulation of Igfals 1 0.15 0.8 0.15 5.00
91 INT226204 Nfkb1 Positive_regulation of Gene_expression of Trim63 1 0.04 0.65 0.14 5.00
92 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14 5.00
93 INT226208 Nfkb1 Positive_regulation of Protein_catabolism of Trim63 1 0.04 0.66 0.14 5.00
94 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12 5.00
95 INT231118 Tlr4 Positive_regulation of Gene_expression of Trim63 1 0.20 0.67 0.11 5.00
96 INT283539 Binding of Litaf and Mad2l1bp 1 0.00 0.67 0.11 5.00
97 INT351032 Binding of CD80 and CD96 1 0.01 0.36 0.09 5.00
98 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
99 INT351031 Binding of CD28 and CD96 1 0.02 0.36 0.09 5.00
100 INT272365 Gene_expression of Adarb1 Positive_regulation of Gene_expression of GRIA1 1 0.00 0.26 0.09 5.00
101 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
102 INT273373 SOCS3 Regulation of Phosphorylation of STAT3 1 0.42 0.06 0.08 5.00
103 INT303337 Binding of SOD1 and Igfals 1 0.06 1.27 0.08 5.00
104 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08 5.00
105 INT326574 Binding of Akt1 and Hsp90ab1 1 0.13 0.17 0.08 5.00
106 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
107 INT229703 Binding of Ppara and Rxrg 1 0.03 0.08 0.08 5.00
108 INT273374 Binding of JAK2 and STAT3 1 0.24 0 0.07 5.00
109 INT273368 Negative_regulation of Binding of JAK2 and STAT3 1 0.28 0 0.07 5.00
110 INT273369 SOCS3 Negative_regulation of JAK1 1 0.03 0 0.07 5.00
111 INT356379 DMD Positive_regulation of Negative_regulation of Utrn 1 0.54 0.84 0.07 5.00
112 INT273372 IL6 Regulation of Regulation of TWIST1 1 0.10 0.1 0.07 5.00
113 INT273366 IL6 Regulation of TWIST1 1 0.06 0.1 0.07 5.00
114 INT203419 Binding of EIF4A1 and Gtf3a 1 0.00 0.5 0.07 5.00
115 INT273363 SOCS3 Regulation of Protein_catabolism of SOCS1 1 0.02 0 0.07 5.00
116 INT273364 SOCS3 Regulation of SOCS1 1 0.02 0 0.07 5.00
117 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 5.00
118 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06 5.00
119 INT267214 Hspb8 Negative_regulation of Cryab 1 0.32 1.56 0.06 5.00
120 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06 5.00
121 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00
122 INT287223 Pdx1 Regulation of Transcription of Insig1 1 0.03 0.56 0.05 5.00
123 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 5.00
124 INT287222 Cytip Regulation of Transcription of Insig1 1 0.02 0.56 0.05 5.00
125 INT287221 Tcf3 Regulation of Transcription of Insig1 1 0.03 0.56 0.05 5.00
126 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04 5.00
127 INT267217 Gene_expression of Hspb8 Negative_regulation of Positive_regulation of Casp3 1 0.14 2.8 0.04 5.00
128 INT326571 Binding of Hsf1 and Hsp90ab1 1 0.16 1.19 0.03 5.00
129 INT231117 Tlr4 Positive_regulation of Transcription of Fbxo32 1 0.15 0.14 0.03 5.00
130 INT326570 Hsp90ab1 Regulation of Csprs 1 0.08 1.17 0.03 5.00
131 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
132 INT332587 MND1 Positive_regulation of Binding of RAPH1 and MND1 1 0.00 2.21 0.03 5.00
133 INT272517 Binding of Ccnd1 and Celf1 3 0.08 0.07 0 5.00
134 INT203400 Olfm1 Negative_regulation of Bex1 1 0.09 0.58 0 5.00
135 INT246152 INS Regulation of S1PR2 1 0.02 0 0 5.00
136 INT303406 Binding of NPAT and Myo1f 1 0.06 0 0 5.00
137 INT203402 Enc1 Negative_regulation of Rtn1 1 0.07 0.58 0 5.00
138 INT246151 INS Negative_regulation of TXLNB 1 0.01 0 0 5.00
139 INT303387 Binding of Laptm5 and Gopc 1 0.01 0 0 5.00
140 INT295573 Igf1 Positive_regulation of Gene_expression of Mstn 1 0.19 0 0 5.00
141 INT354097 Timp1 Negative_regulation of Localization of NFKB2 1 0.04 0.94 0 5.00
142 INT218308 Binding of HPRT1 and Grb10 1 0.26 0.07 0 5.00
143 INT203405 Vsnl1 Negative_regulation of Bex1 1 0.19 0.58 0 5.00
144 INT303397 Binding of Jag1 and Gopc 1 0.13 0 0 5.00
145 INT311390 Mbnl1 Positive_regulation of Celf1 1 0.26 0.48 0 5.00
146 INT311387 Binding of Celf1 and Mbnl1 1 0.20 0.25 0 5.00
147 INT311405 CCND3 Regulation of Celf1 1 0.41 0.14 0 5.00
148 INT281609 Foxo3 Positive_regulation of Transcription of Trim63 1 0.29 0 0 5.00
149 INT246148 INS Regulation of TXLNB 1 0.00 0 0 5.00
150 INT203411 Mllt11 Negative_regulation of Nptn 1 0.08 0.58 0 5.00
151 INT299626 Binding of IGF1 and IGFBP3 Positive_regulation of IGF1 1 0.02 0.39 0 5.00
152 INT203418 Enc1 Negative_regulation of Rtn4 1 0.08 0.58 0 5.00
153 INT325904 Binding of F2 and Wbp5 1 0.01 1.22 0 5.00
154 INT295574 Binding of Igf1 and Mstn 1 0.16 0.08 0 5.00
155 INT325898 Negative_regulation of Binding of F2 and Gopc 1 0.03 0.14 0 5.00
156 INT303333 MAPK1 Positive_regulation of Mknk2 1 0.04 0.14 0 5.00
157 INT340916 hop Regulation of Dnahc8 1 0.02 0.24 0 5.00
158 INT325910 Wbp5 Positive_regulation of Positive_regulation of F2 1 0.01 0.67 0 5.00
159 INT303331 Mtor Positive_regulation of Rps6kb1 1 0.07 0.07 0 5.00
160 INT303403 Binding of Laptm5 and Myh3 1 0.02 0 0 5.00
161 INT303332 ras Positive_regulation of Raf1 1 0.02 0.07 0 5.00
162 INT311404 Binding of CDKN2A and Celf1 1 0.32 0.07 0 5.00
163 INT303398 Jag1 Positive_regulation of Protein_catabolism of Myh3 1 0.52 0 0 5.00
164 INT283543 Binding of GARS and Setx 1 0.01 3.71 0 5.00
165 INT203406 Cap2 Negative_regulation of Rtn4 1 0.07 0.59 0 5.00
166 INT351029 AGK Regulation of VEGFA 1 0.00 0.82 0 5.00
167 INT203414 Vsnl1 Negative_regulation of Nptn 1 0.16 0.58 0 5.00
168 INT203394 Vsnl1 Negative_regulation of Chn1 1 0.17 0.58 0 5.00
169 INT246147 AKT1 Positive_regulation of Phosphorylation of RNF123 1 0.01 0.09 0 5.00
170 INT203410 Vsnl1 Negative_regulation of Rtn4 1 0.18 0.58 0 5.00
171 INT303405 Binding of NPAT and Jag1 1 0.39 0 0 5.00
172 INT340914 Binding of Hsp90aa1 and Fkbp6 1 0.12 0.26 0 5.00
173 INT246144 FBXO32 Regulation of C2 1 0.08 0 0 5.00
174 INT325900 Binding of Dio1 and Wbp5 1 0.00 0.25 0 5.00
175 INT203398 Enc1 Negative_regulation of Nptn 1 0.07 0.59 0 5.00
176 INT311389 Positive_regulation of Binding of Celf1 and Eif2s2 1 0.17 0.59 0 5.00
177 INT303342 Binding of NPAT and TCAP 1 0.40 0 0 5.00
178 INT325902 Binding of F2 and Fgg 1 0.01 0 0 5.00
179 INT311381 Phosphorylation of Akt1 Regulation of Celf1 1 0.10 0.14 0 5.00
180 INT203409 Cap2 Negative_regulation of Bex1 1 0.07 0.58 0 5.00
181 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0 5.00
182 INT311379 Celf1 Negative_regulation of Mbnl1 1 0.24 0.26 0 5.00
183 INT283542 Binding of SPG19 and Setx 1 0.06 3.69 0 5.00
184 INT203417 Mllt11 Negative_regulation of Rtn1 1 0.08 0.58 0 5.00
185 INT303404 Binding of TCAP and Jag1 1 0.39 0 0 5.00
186 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0 5.00
187 INT311385 Gopc Regulation of Celf1 1 0.04 0.14 0 5.00
188 INT272516 Binding of Celf1 and Tpt1 2 0.05 0.07 0 5.00
189 INT246145 INS Negative_regulation of S1PR2 1 0.03 0 0 5.00
190 INT311380 Positive_regulation of Celf1 Negative_regulation of Mbnl1 1 0.26 0.26 0 5.00
191 INT203415 Olfm1 Negative_regulation of Chn1 1 0.08 0.58 0 5.00
192 INT295578 Binding of Mstn and Gprasp1 1 0.23 0.19 0 5.00
193 INT246149 AKT1 Regulation of Gene_expression of RNF123 1 0.02 0.09 0 5.00
194 INT303334 Binding of SOS1 and Grb2 1 0.00 0.11 0 5.00
195 INT325908 Binding of Wbp5 and Fgg 1 0.00 1.2 0 5.00
196 INT303257 MAPK1 Positive_regulation of NEK4 1 0.05 0.14 0 5.00
197 INT340563 Gopc Regulation of Phosphorylation of Mapk14 1 0.04 0.91 0 5.00
198 INT325903 Binding of F2 and Gopc 1 0.02 0.26 0 5.00
199 INT203408 Vsnl1 Negative_regulation of Cap2 1 0.15 0.58 0 5.00
200 INT295577 Gene_expression of Mstn Positive_regulation of Phosphorylation of Akt1 1 0.21 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Muscular Atrophy. They are ordered first by their pain relevance and then by number of times they were reported in Muscular Atrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT157686 Gene_expression of Fbxo32 14 0.75 8.68 0.9 100.00
2 INT276881 Regulation of FBXO32 2 0.44 1.71 0.13 100.00
3 INT226164 Gene_expression of Trim63 5 0.68 4.77 0.49 100.00
4 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86 100.00
5 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5 100.00
6 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 100.00
7 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 99.96
8 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.90
9 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72 99.88
10 INT303371 Binding of Trim54 1 0.35 0.29 0 99.88
11 INT226170 Positive_regulation of Gene_expression of Trim63 5 0.44 3.96 0.31 99.80
12 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 99.80
13 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 99.72
14 INT266688 Regulation of Cs 1 0.12 0.33 0.04 99.72
15 INT266687 Regulation of Regulation of Cpox 1 0.16 0.38 0.04 99.72
16 INT303361 Positive_regulation of Trim63 1 0.16 0.29 0 99.68
17 INT311337 Positive_regulation of Uts2r 3 0.12 1.34 0.05 99.68
18 INT102745 Positive_regulation of Hmbs 17 0.61 12.41 0.78 99.66
19 INT226166 Positive_regulation of Positive_regulation of thd 1 0.04 0.99 0 99.66
20 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 99.62
21 INT76649 Gene_expression of TRIM54 12 0.22 1.91 5.55 99.60
22 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.60
23 INT303349 Positive_regulation of Jag1 5 0.57 1.23 0 99.56
24 INT303374 Negative_regulation of Jag1 2 0.48 0.9 0.23 99.56
25 INT303367 Negative_regulation of Positive_regulation of Jag1 1 0.35 0.28 0 99.56
26 INT12156 Positive_regulation of MET 43 0.67 17.75 12.64 99.52
27 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 99.44
28 INT318951 Positive_regulation of Gene_expression of AA467197 1 0.22 0.87 0.41 99.40
29 INT318945 Gene_expression of AA467197 1 0.30 1.44 0.79 99.40
30 INT212058 Positive_regulation of Psmb10 1 0.01 11.89 0.4 99.34
31 INT181829 Binding of Ppargc1a 16 0.48 9.61 0.34 99.34
32 INT316981 Negative_regulation of NAA25 1 0.04 0.86 0.09 99.32
33 INT129105 Gene_expression of Mstn 95 0.76 29.96 0.32 99.28
34 INT218285 Positive_regulation of Gene_expression of Mstn 51 0.68 15.72 0.08 99.28
35 INT246180 Gene_expression of FBXO32 10 0.65 4.21 0.79 99.24
36 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33 99.16
37 INT181833 Negative_regulation of Ppargc1a 14 0.57 6.01 0.52 99.14
38 INT179550 Phosphorylation of Ywhaq 8 0.03 6.24 1.48 99.06
39 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.00
40 INT150032 Gene_expression of ALOX12 7 0.65 0.61 0.09 99.00
41 INT276883 Positive_regulation of FBXO32 7 0.67 2.63 0.07 98.94
42 INT276882 Positive_regulation of TRIM54 1 0.16 1.77 0 98.94
43 INT157690 Negative_regulation of Gene_expression of Fbxo32 4 0.41 1.36 0.4 98.92
44 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 98.88
45 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 98.88
46 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 98.88
47 INT217732 Localization of MTOR 11 0.56 3.19 0.03 98.82
48 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69 98.78
49 INT267198 Positive_regulation of Cryab 1 0.46 6.69 0.13 98.76
50 INT26363 Negative_regulation of CS 8 0.26 2.49 2.36 98.76
51 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03 98.74
52 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 98.72
53 INT303352 Gene_expression of Jag1 19 0.73 7.68 1.89 98.68
54 INT303347 Positive_regulation of Gene_expression of Jag1 6 0.65 4.06 0.77 98.68
55 INT117112 Negative_regulation of Mapk1 87 0.56 40.34 31.18 98.68
56 INT303348 Positive_regulation of Transcription of Jag1 1 0.44 0.64 0 98.68
57 INT286388 Transcription of Jag1 2 0.65 0.64 0 98.68
58 INT218287 Positive_regulation of Fbxo32 3 0.49 0.51 0.22 98.64
59 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 98.60
60 INT327031 Negative_regulation of Akt2 1 0.38 0.27 0 98.60
61 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 98.58
62 INT72759 Transcription of Cpox 40 0.39 17.26 10 98.56
63 INT77555 Positive_regulation of thd 8 0.05 7.82 1.06 98.48
64 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 98.48
65 INT18583 Positive_regulation of Gene_expression of Ins1 67 0.50 49.72 8.26 98.48
66 INT253918 Positive_regulation of Gene_expression of Rnf123 1 0.07 1.61 0.25 98.40
67 INT253917 Gene_expression of Rnf123 3 0.08 1.98 0.3 98.40
68 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 98.36
69 INT303365 Protein_catabolism of Myo1f 1 0.10 0.29 0 98.28
70 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 98.16
71 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49 98.16
72 INT211584 Gene_expression of Dmpk 32 0.73 12.28 0.46 98.16
73 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 98.08
74 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29 98.08
75 INT142967 Regulation of Regulation of EIF3K 1 0.00 0.76 0.09 98.06
76 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 98.04
77 INT142966 Regulation of EIF3K 2 0.06 0.76 0.09 97.90
78 INT162430 Negative_regulation of Positive_regulation of Ar 1 0.21 1.52 0.07 97.86
79 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49 97.76
80 INT158374 Negative_regulation of Aadac 13 0.07 7.19 1.76 97.72
81 INT273867 Binding of Jag1 18 0.45 3.14 0.25 97.64
82 INT162801 Localization of CALR 7 0.73 8.69 0.6 97.60
83 INT227519 Positive_regulation of Hspa9 22 0.55 16.38 3.83 97.56
84 INT218294 Positive_regulation of Gene_expression of Fbxo32 7 0.49 5.84 0.34 97.48
85 INT162432 Positive_regulation of Ar 3 0.23 2.34 0.11 97.42
86 INT162428 Localization of Ar 4 0.37 2.4 0.07 97.42
87 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 97.36
88 INT340908 Negative_regulation of Gene_expression of ST13 1 0.41 0.3 0.03 97.32
89 INT246194 Regulation of Phosphorylation of MTOR 2 0.34 0.31 0 97.16
90 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 97.08
91 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96 97.08
92 INT2217 Positive_regulation of Positive_regulation of Ins1 21 0.69 7.66 6.32 96.88
93 INT142971 Negative_regulation of Positive_regulation of ID2 1 0.20 0.69 0.09 96.72
94 INT156207 Negative_regulation of Phosphorylation of MTOR 5 0.58 2.33 0.25 96.68
95 INT340886 Binding of Hspa8 1 0.34 0.23 0.04 96.60
96 INT272949 Positive_regulation of Myod1 6 0.36 5.31 0.14 96.48
97 INT605 Regulation of Acot1 61 0.62 10.7 26.34 96.48
98 INT22721 Regulation of Protein_catabolism of Acot1 2 0.23 0.17 0.53 96.48
99 INT193015 Positive_regulation of Gene_expression of EPAS1 6 0.32 8.77 0.21 96.44
100 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 96.44
101 INT339003 Gene_expression of ST13 3 0.75 0.37 1.24 96.44
102 INT340906 Positive_regulation of Gene_expression of ST13 1 0.67 0.37 0.06 96.44
103 INT142969 Positive_regulation of ID2 1 0.21 0.68 0.09 96.34
104 INT156204 Phosphorylation of MTOR 15 0.82 3.99 0.21 96.28
105 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 96.28
106 INT276885 Positive_regulation of Transcription of TRIM54 1 0.11 0.3 0 96.28
107 INT276886 Transcription of TRIM54 1 0.13 0.3 0 96.28
108 INT61626 Transcription of IL6 73 0.72 42.04 17.86 96.28
109 INT231093 Negative_regulation of Fbxo32 3 0.41 0.55 0.12 96.16
110 INT272469 Negative_regulation of Gene_expression of Myod1 5 0.39 2.82 0.07 96.12
111 INT272484 Negative_regulation of Myod1 8 0.39 6.77 0.2 96.12
112 INT129630 Regulation of Sod1 6 0.44 4.94 0.73 96.04
113 INT20060 Protein_catabolism of Acot1 6 0.56 0.22 2.45 96.00
114 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 95.96
115 INT276878 Transcription of FBXO32 2 0.69 0.3 0 95.92
116 INT138286 Regulation of Positive_regulation of Akt1 13 0.45 4.93 2.22 95.88
117 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 95.84
118 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 95.84
119 INT191925 Positive_regulation of Gene_expression of Hspb8 18 0.68 26.99 0.83 95.80
120 INT267193 Positive_regulation of Gene_expression of Cryab 6 0.41 5.71 0.17 95.80
121 INT116314 Gene_expression of Myod1 38 0.70 16.6 0.89 95.72
122 INT218288 Positive_regulation of Gene_expression of Foxo3 1 0.40 0.1 0 95.72
123 INT218283 Gene_expression of Foxo3 1 0.62 0.1 0 95.72
124 INT231091 Protein_catabolism of Psmb8 1 0.01 1.87 0 95.52
125 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 95.52
126 INT69880 Positive_regulation of Positive_regulation of Gtf3a 8 0.03 5.25 0.68 95.52
127 INT231089 Protein_catabolism of Ros1 1 0.13 1.14 0 95.52
128 INT46605 Positive_regulation of NAA50 17 0.49 6.33 1.76 95.44
129 INT175455 Gene_expression of Hspb8 54 0.76 59.87 3.9 95.40
130 INT181818 Gene_expression of Ppargc1a 50 0.78 24.33 2.71 95.36
131 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 95.24
132 INT19511 Localization of Il6 212 0.81 118.17 67.67 95.24
133 INT267196 Gene_expression of Cryab 17 0.64 22.5 0.38 95.16
134 INT101213 Gene_expression of MTUS1 2 0.02 2.72 0.09 95.06
135 INT102744 Positive_regulation of Gene_expression of Hmbs 4 0.70 2.97 0.35 95.04
136 INT102747 Gene_expression of Hmbs 17 0.78 10.53 1.34 95.04
137 INT102746 Negative_regulation of Hmbs 11 0.59 8.35 0.77 95.00
138 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83 94.80
139 INT327033 Negative_regulation of Phosphorylation of Mtor 3 0.07 1.38 0.23 94.80
140 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78 94.40
141 INT267204 Regulation of Positive_regulation of Hspb8 1 0.60 2.73 0.07 94.04
142 INT287206 Regulation of Gene_expression of Htt 6 0.50 3.27 0.57 94.00
143 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55 93.96
144 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 93.64
145 INT212055 Protein_catabolism of Pif 1 0.02 3.09 0.19 93.64
146 INT212056 Positive_regulation of Protein_catabolism of Pif 1 0.01 1.59 0.1 93.64
147 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 93.44
148 INT19366 Negative_regulation of Localization of Ca2 33 0.50 6.51 6.61 93.40
149 INT4822 Localization of Ca2 417 0.80 99.57 96.45 93.40
150 INT139678 Positive_regulation of Hspb8 23 0.68 23.94 1.85 93.36
151 INT142970 Positive_regulation of Gene_expression of ID2 2 0.40 2.39 0.11 93.28
152 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62 93.16
153 INT185186 Positive_regulation of Pif 3 0.60 4.59 0.68 93.16
154 INT129106 Negative_regulation of Mstn 102 0.57 30.57 0.49 92.76
155 INT36293 Gene_expression of Mtor 24 0.25 14.5 2.04 92.40
156 INT9210 Regulation of IL6 166 0.62 125.61 49.95 92.40
157 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33 92.40
158 INT303350 Regulation of Myo1f 1 0.09 0.26 0 92.28
159 INT142968 Negative_regulation of Gene_expression of ID2 1 0.19 0.98 0.11 92.16
160 INT231103 Positive_regulation of Protein_catabolism of Psmb8 1 0.01 0.73 0 92.00
161 INT132191 Regulation of Cabin1 6 0.45 2.96 1.28 91.76
162 INT276877 Positive_regulation of Positive_regulation of FBXO32 1 0.27 0.34 0 91.72
163 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 91.24
164 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65 91.12
165 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34 90.92
166 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17 90.88
167 INT111462 Negative_regulation of Phosphorylation of Mapk1 45 0.57 19.49 15.59 90.64
168 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 90.32
169 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 90.32
170 INT183910 Negative_regulation of Gene_expression of Lbp 10 0.35 9.78 6.15 90.28
171 INT267189 Positive_regulation of Positive_regulation of Hspb8 1 0.68 2.49 0.03 90.08
172 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 89.52
173 INT226171 Protein_catabolism of Trim63 1 0.24 1.85 0.19 89.36
174 INT226168 Regulation of Protein_catabolism of Trim63 1 0.12 0.56 0.05 89.36
175 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 89.32
176 INT222291 Positive_regulation of Trim63 3 0.50 0.94 0.04 89.28
177 INT222294 Positive_regulation of Transcription of Trim63 2 0.36 0.17 0 89.28
178 INT69009 Regulation of Binding of Nfkb1 9 0.27 9.86 2.58 89.12
179 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65 89.12
180 INT9664 Binding of LBP 127 0.48 94.9 63.42 89.04
181 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7 89.00
182 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 88.68
183 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 88.68
184 INT218297 Positive_regulation of Mstn 44 0.68 21.87 0.17 88.48
185 INT8541 Gene_expression of Csrp1 42 0.76 23.72 6.9 88.36
186 INT226177 Positive_regulation of Transcription of thd 1 0.04 1.08 0 87.96
187 INT226837 Positive_regulation of Gene_expression of Pax7 2 0.49 3.59 0.04 87.92
188 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 87.92
189 INT1354 Negative_regulation of Acot1 87 0.43 15.01 36.44 87.92
190 INT340546 Positive_regulation of Pax7 1 0.49 1.07 0 87.92
191 INT22719 Negative_regulation of Negative_regulation of Acot1 5 0.43 0.77 2.2 87.92
192 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61 87.92
193 INT18323 Negative_regulation of Localization of Ins1 122 0.58 45.74 23.04 87.72
194 INT181808 Gene_expression of Pax7 18 0.54 6.22 0.26 87.52
195 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 87.52
196 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97 87.52
197 INT226182 Transcription of thd 3 0.05 1.08 0.15 87.44
198 INT3214 Localization of Ins1 527 0.80 196.9 79.26 87.12
199 INT71496 Positive_regulation of Hspb1 15 0.69 14.7 6.86 86.96
200 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 86.76
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