D:Musculoskeletal Cancer

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Disease Term
Synonyms Musculoskeletal Cancers, MUSCULOSKELETAL CARCINOMA, Musculoskeletal Carcinomas, Musculoskeletal Dysplasia, MUSCULOSKELETAL HYPERPLASIA, Musculoskeletal Neoplasia, Musculoskeletal Neoplasm, MUSCULOSKELETAL NEOPLASMS, Musculoskeletal Sarcoma, Musculoskeletal Sarcomata, Musculoskeletal Tumor
Documents 79
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Musculoskeletal Cancer. They are ordered first by their relevance to Musculoskeletal Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT301121 Tgm7 Regulation of Gene_expression of Mmp2 1 0.52 2.53 0.16 37.88
2 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
3 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
4 INT301122 Tgm7 Negative_regulation of Akt1 1 0.38 2.78 0.07 5.00
5 INT301128 Binding of Tgm7 and Gm9662 1 0.01 0.12 0.04 5.00
6 INT301130 Binding of VEGFA and Mmp2 1 0.03 1.33 0.03 5.00
7 INT301126 Tgm7 Regulation of Localization of Mmp2 1 0.38 0.2 0.03 5.00
8 INT301131 Tgm7 Regulation of Gene_expression of VEGFA 1 0.03 1.29 0 5.00
9 INT301127 Tgm7 Regulation of Positive_regulation of Akt1 1 0.47 0.48 0 5.00
10 INT301129 Tgm7 Negative_regulation of Akt1 Negative_regulation of Localization of Mmp2 1 0.38 0.55 0 5.00
11 INT301125 Tgm7 Regulation of Gene_expression of Cd34 1 0.40 1.29 0 5.00
12 INT301124 Tgm7 Regulation of Akt1 1 0.40 0 0 5.00
13 INT301123 Tgm7 Regulation of Positive_regulation of Mmp2 1 0.23 1.47 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Musculoskeletal Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Musculoskeletal Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT89118 Protein_catabolism of MIB1 1 0.26 1.18 0.12 86.00
2 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 61.84
3 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 61.84
4 INT301109 Localization of Tgm7 1 0.63 2.25 0.04 49.36
5 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 45.84
6 INT156827 Localization of MRI1 25 0.65 16.06 8.33 18.32
7 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 14.40
8 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 13.96
9 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
10 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
11 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
12 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
13 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
14 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
15 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
16 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
17 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
18 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42 5.00
19 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
20 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 5.00
21 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
22 INT114420 Negative_regulation of Pik3r1 67 0.54 34.86 12.82 5.00
23 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
24 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76 5.00
25 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 5.00
26 INT111398 Localization of Mmp2 37 0.76 23.78 7.17 5.00
27 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 5.00
28 INT134657 Localization of Akt1 37 0.68 11.58 4.62 5.00
29 INT122569 Negative_regulation of Gene_expression of Akt1 34 0.54 17.15 4.44 5.00
30 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 5.00
31 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14 5.00
32 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79 5.00
33 INT124655 Negative_regulation of PECAM1 13 0.23 10.32 3.78 5.00
34 INT157687 Regulation of Gene_expression of Akt1 9 0.62 4.96 3.27 5.00
35 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81 5.00
36 INT97902 Gene_expression of AGGF1 17 0.11 13.45 2.51 5.00
37 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47 5.00
38 INT132903 Gene_expression of Cd34 65 0.72 33.95 2.2 5.00
39 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17 5.00
40 INT109967 Gene_expression of Mmv7 21 0.35 15.66 1.7 5.00
41 INT173100 Binding of KDR 39 0.39 22.48 0.81 5.00
42 INT128472 Negative_regulation of CD34 7 0.42 3.92 0.58 5.00
43 INT283569 Protein_catabolism of Mmp2 5 0.77 3.25 0.56 5.00
44 INT143125 Binding of FLT1 48 0.40 13.6 0.51 5.00
45 INT141706 Localization of HLA-DRB1 9 0.75 4.87 0.48 5.00
46 INT301116 Gene_expression of Tgm7 1 0.65 3.89 0.24 5.00
47 INT301111 Regulation of Gene_expression of Tgm7 1 0.38 0.36 0.17 5.00
48 INT301112 Negative_regulation of Tgm7 1 0.36 1.53 0.12 5.00
49 INT182469 Positive_regulation of Gene_expression of Cd34 6 0.43 1.27 0.12 5.00
50 INT301119 Negative_regulation of Gene_expression of Mmv7 3 0.06 2.13 0.08 5.00
51 INT264884 Gene_expression of LIMA1 1 0.65 0.68 0.06 5.00
52 INT301115 Negative_regulation of Positive_regulation of Mmp2 3 0.38 3.04 0.06 5.00
53 INT301114 Binding of Tgm7 1 0.31 0.12 0.04 5.00
54 INT301113 Regulation of Tgm7 1 0.38 0.39 0.04 5.00
55 INT301120 Negative_regulation of Gene_expression of Tgm7 1 0.36 0.85 0.04 5.00
56 INT301117 Gene_expression of Tcf12 2 0.42 1.42 0 5.00
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