D:Myelodysplastic Syndromes

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Disease Term
Synonyms Agnogenic Myeloid Metaplasia Essential Thrombocyte, Dysmyelopoiesis, Dysmyelopoietic Syndrome, Dysmyelopoietic Syndromes, Essential Thrombocythaemia, Essential Thrombocythemia, MDS, MYELODYSPLASIA, Myelodysplastic Syndrome, MYELOID DYSPLASIA, Myeloproliferative Disorder
Documents 771
Hot Single Events 200
Hot Interactions 32

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Myelodysplastic Syndromes. They are ordered first by their relevance to Myelodysplastic Syndromes and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT350523 ABL1 Negative_regulation of Pmf1 1 0.01 2.19 0 100.00
2 INT350504 ABL1 Negative_regulation of JAK2 1 0.20 2.18 0 99.80
3 INT200816 Jak2 Positive_regulation of Binding of Mvd 1 0.19 1.51 0.03 99.36
4 INT200815 Binding of Epo and Jak2 1 0.36 0.98 0.03 99.18
5 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61 99.08
6 INT200809 Binding of Akt1 and Epo 1 0.23 0.98 0.03 99.08
7 INT200823 Akt1 Negative_regulation of Binding of Akt1 and Insrr 1 0.00 0.98 0.03 99.08
8 INT315814 Tst Positive_regulation of Localization of RTEL1 1 0.02 2.19 0 98.56
9 INT200807 Jak2 Positive_regulation of Mvd 1 0.18 3.46 0.06 98.56
10 INT200817 Akt1 Positive_regulation of Negative_regulation of Fgr 1 0.25 1.02 0 97.12
11 INT200812 Akt1 Positive_regulation of Negative_regulation of Hck 1 0.25 1.02 0 96.76
12 INT200818 Akt1 Positive_regulation of Negative_regulation of Lyn 1 0.25 1.02 0 96.56
13 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03 95.80
14 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03 95.80
15 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03 95.56
16 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 95.24
17 INT106486 Gene_expression of CD177 Negative_regulation of Gene_expression of Bcl2l1 1 0.01 1.87 0.04 95.12
18 INT200811 Epo Positive_regulation of Akt1 2 0.30 1.77 0.09 95.00
19 INT235385 INCENP Negative_regulation of Bche 1 0.01 0.19 0.11 94.88
20 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 94.64
21 INT200820 Epo Positive_regulation of Src 1 0.25 1.41 0.03 94.40
22 INT200819 Epo Positive_regulation of Gene_expression of Jak2 1 0.49 0.91 0 92.56
23 INT277765 Binding of BCR and Abl1 1 0.18 1.55 0.03 92.12
24 INT106487 Gene_expression of CD177 Negative_regulation of Gene_expression of Mpl 1 0.02 1.74 0.04 90.72
25 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03 90.20
26 INT301083 Binding of BCS1L and MYH7 1 0.36 1.53 0.19 87.60
27 INT281307 Binding of Selp and Selplg 1 0.01 0.76 0.17 86.12
28 INT281318 Binding of Selp and Selplg Positive_regulation of Gene_expression of Selplg 1 0.00 0.76 0.17 86.12
29 INT350505 Negative_regulation of Binding of HSP90AA1 and JAK2 1 0.07 1.5 0 85.24
30 INT350503 Binding of HSP90AA1 and JAK2 1 0.06 1.39 0 85.24
31 INT284915 Binding of CDKN2B and HIST2H3C 1 0.05 0.43 0 81.12
32 INT325771 EPOR Positive_regulation of MAPK1 1 0.16 0.29 0 81.12
33 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78 76.60
34 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74 75.24
35 INT142751 Thpo Positive_regulation of Positive_regulation of Nfkb1 1 0.47 1.04 0.24 73.48
36 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0 73.20
37 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0 73.20
38 INT248765 Binding of RUNX1 and CSF2 1 0.02 1.36 0 71.92
39 INT301244 Rb1 Regulation of Hbp1 1 0.03 0.75 0 71.32
40 INT301246 Binding of HMGB1 and Hbp1 1 0.03 0.74 0 71.32
41 INT281302 Binding of Itgam and Fgg 1 0.00 0.62 0.15 67.12
42 INT281315 Binding of Gp1bb and Itgam 1 0.00 0.62 0.15 67.12
43 INT312304 Binding of JAK2 and VEGFA 1 0.30 0.82 0 67.04
44 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 66.60
45 INT200821 Binding of Jak2 and Mvd 1 0.14 0.68 0.04 64.64
46 INT326249 Prkcg Positive_regulation of EPHB2 1 0.06 0.63 0.13 64.60
47 INT326252 EPHB2 Positive_regulation of ras 1 0.03 0.62 0.13 64.60
48 INT326246 Prkcg Positive_regulation of ras 1 0.01 0.62 0.13 63.84
49 INT326247 Prkcg Positive_regulation of Prkaca 1 0.00 0.62 0.13 63.84
50 INT326248 Prkaca Positive_regulation of ras 1 0.00 0.62 0.13 63.84
51 INT301238 Gene_expression of Mir29a Positive_regulation of Runx1 1 0.00 1.39 0 54.88
52 INT177980 CSF1R Regulation of PXN 1 0.07 0.48 0.11 54.52
53 INT281319 Binding of F7 and tf 1 0.24 1 0.16 53.96
54 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03 53.04
55 INT169962 Binding of Rb1 and E2f4 1 0.25 0.56 0.04 52.16
56 INT169960 Binding of Rbl2 and E2f4 1 0.27 1.06 0.04 51.92
57 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61 50.48
58 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 50.00
59 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 50.00
60 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0 50.00
61 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0 50.00
62 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0 50.00
63 INT284995 Binding of HDAC1 and Sin3a 1 0.00 0.13 0 50.00
64 INT289293 Binding of CD59 and Cd33 1 0.02 1.06 0 49.76
65 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0 49.76
66 INT289295 Binding of CD59 and Fcgr3 1 0.01 1.06 0 49.76
67 INT289300 Binding of CD59 and Fut4 1 0.01 1.06 0 49.76
68 INT289299 Binding of CD59 and Cd14 1 0.02 1.06 0 49.76
69 INT301241 Mir29a Positive_regulation of Runx1 1 0.00 2.85 0 48.72
70 INT305208 Pbrgcsf1 Positive_regulation of Localization of VEGFA 1 0.05 0.22 0.04 39.76
71 INT320346 Binding of Ngfr and Np4 1 0.01 0 0 33.04
72 INT305204 Pbrgcsf1 Positive_regulation of Gene_expression of Epo 1 0.27 0.6 0.27 28.12
73 INT257740 SAGE1 Positive_regulation of Gene_expression of AXL 1 0.07 0.72 0.27 20.08
74 INT177978 Binding of CSF1R and SNRNP70 1 0.02 1.49 0.28 17.36
75 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 15.44
76 INT332588 Binding of RAPH1 and MND1 1 0.01 3.88 0.07 11.72
77 INT177982 Binding of RUNX1 and SNRNP70 1 0.01 0.89 0.21 7.76
78 INT305202 Binding of Cebpz and Pbrgcsf1 1 0.02 0.48 0.35 7.36
79 INT305193 Binding of Epo and Cebpz 1 0.05 0.48 0.35 6.80
80 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.72
81 INT234380 Negative_regulation of Binding of CD40 and CD40LG 1 0.16 1.4 0.04 5.72
82 INT136514 Binding of Grm1 and Grm5 4 0.12 1.8 3.9 5.00
83 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79 5.00
84 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8 5.00
85 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65 5.00
86 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06 5.00
87 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04 5.00
88 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92 5.00
89 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
90 INT11684 Binding of CSF2 and IL3 6 0.36 3.3 0.72 5.00
91 INT282139 Grm1 Regulation of Grip2 1 0.00 0.62 0.69 5.00
92 INT282141 Grm5 Regulation of Grip2 1 0.00 0.61 0.69 5.00
93 INT257745 SAGE1 Positive_regulation of AXL 1 0.07 1.96 0.69 5.00
94 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63 5.00
95 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62 5.00
96 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61 5.00
97 INT282142 Grm1 Positive_regulation of Positive_regulation of Trib3 1 0.01 0.27 0.57 5.00
98 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52 5.00
99 INT177981 Binding of RUNX1 and SLC22A4 1 0.08 1.04 0.5 5.00
100 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
101 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49 5.00
102 INT291963 Phex Negative_regulation of Gene_expression of Grin1 1 0.06 0.81 0.43 5.00
103 INT254460 Binding of Calm2 and Ca2 5 0.03 0.48 0.43 5.00
104 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
105 INT291965 Phex Negative_regulation of Pag1 1 0.05 0.82 0.43 5.00
106 INT231303 Binding of Prnp and Helt 1 0.02 3.23 0.41 5.00
107 INT231304 Prnp Negative_regulation of Grin2d 2 0.38 0.5 0.4 5.00
108 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39 5.00
109 INT257738 PIK3CA Regulation of Localization of ACTN4 1 0.16 1.03 0.39 5.00
110 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
111 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35 5.00
112 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35 5.00
113 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 0.26 1.04 0.34 5.00
114 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
115 INT330182 Binding of ITIH2 and BRD4 1 0.05 0.37 0.32 5.00
116 INT353208 NEUROG2 Positive_regulation of Gene_expression of HTR1A 1 0.05 0.35 0.31 5.00
117 INT231306 Prnp Regulation of Grin1 1 0.60 0.35 0.31 5.00
118 INT257743 Binding of PIK3CA and SHC1 1 0.21 1.03 0.31 5.00
119 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31 5.00
120 INT257735 GAS6 Positive_regulation of Gene_expression of SAGE1 1 0.04 0.98 0.31 5.00
121 INT257739 SAGE1 Positive_regulation of DDR1 1 0.00 0.91 0.31 5.00
122 INT257744 Binding of PIK3R2 and SHC1 1 0.08 0.96 0.28 5.00
123 INT247949 Cdk5r1 Positive_regulation of Cdk5 1 0.26 1.12 0.28 5.00
124 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27 5.00
125 INT177977 RUNX1 Regulation of CSF1R 1 0.14 1 0.27 5.00
126 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
127 INT348924 Mmp1 Regulation of Gene_expression of Renbp 1 0.03 0.95 0.26 5.00
128 INT330976 Igh-Dex Positive_regulation of Gene_expression of VDR 1 0.01 1.11 0.23 5.00
129 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
130 INT326831 Cdk5r2 Positive_regulation of Binding of Cdk5r1 1 0.01 0.95 0.21 5.00
131 INT305203 Epo Positive_regulation of Gene_expression of Neurog1 1 0.06 0.4 0.21 5.00
132 INT326834 Cdk5r2 Positive_regulation of Cdk5 1 0.02 0.96 0.21 5.00
133 INT231305 Positive_regulation of Binding of Prnp and Helt 1 0.03 1.63 0.19 5.00
134 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
135 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00
136 INT330514 Vegfa Positive_regulation of VEGFA 1 0.18 0.5 0.18 5.00
137 INT241250 Binding of Pkd2 and Trpc1 1 0.23 0.3 0.17 5.00
138 INT304458 Binding of P2rx4 and P2rx6 1 0.14 0 0.17 5.00
139 INT355410 Ins1 Regulation of Gene_expression of Dbi 1 0.07 0.57 0.16 5.00
140 INT260059 AKTIP Positive_regulation of TRPA1 1 0.02 0 0.15 5.00
141 INT304463 Ass1 Positive_regulation of P2rx4 1 0.01 0 0.14 5.00
142 INT231274 Nrg1 Regulation of Gene_expression of Akt1 1 0.19 0 0.14 5.00
143 INT227485 pk Positive_regulation of Ptger2 1 0.06 0.91 0.14 5.00
144 INT355408 Ins1 Regulation of Dbi 1 0.07 0.58 0.14 5.00
145 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14 5.00
146 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13 5.00
147 INT305207 Pbrgcsf1 Positive_regulation of Gtf3a 1 0.00 0.36 0.13 5.00
148 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13 5.00
149 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13 5.00
150 INT305194 Bcl2 Positive_regulation of Epo 1 0.06 0.29 0.12 5.00
151 INT300570 Binding of IL1RN and SUGT1P2 1 0.01 0.43 0.12 5.00
152 INT281301 Stx2 Positive_regulation of Localization of F3 1 0.10 0.19 0.11 5.00
153 INT281311 Tlr4 Positive_regulation of Localization of F3 1 0.04 0.19 0.11 5.00
154 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1 5.00
155 INT241248 Binding of Pkd1 and Pkd2 3 0.22 1.52 0.1 5.00
156 INT241252 Binding of Pkd1 and Tbpl1 1 0.02 0.79 0.1 5.00
157 INT254456 Negative_regulation of Binding of Calm2 and Ca2 1 0.03 0 0.1 5.00
158 INT231273 Binding of Egfr and Nrg1 1 0.12 0 0.09 5.00
159 INT281309 Tlr4 Positive_regulation of Gene_expression of F3 1 0.04 0.15 0.09 5.00
160 INT241249 Pkd2 Regulation of Trpc1 1 0.21 0.14 0.09 5.00
161 INT304460 Ass1 Positive_regulation of Xist 1 0.00 0 0.09 5.00
162 INT231561 Binding of CYP2A and PPIG 1 0.06 0 0.09 5.00
163 INT281312 Stx2 Positive_regulation of Gene_expression of F3 1 0.10 0.15 0.09 5.00
164 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09 5.00
165 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 5.00
166 INT238628 Mef2c Regulation of Gene_expression of Arc 1 0.09 0.16 0.08 5.00
167 INT330955 HOMER1 Positive_regulation of Gene_expression of VDR 1 0.01 0.99 0.08 5.00
168 INT251623 Car2 Regulation of Gene_expression of Fig4 1 0.02 0.31 0.08 5.00
169 INT231301 Prnp Regulation of Regulation of Grin1 1 0.26 0.24 0.08 5.00
170 INT238625 Mef2c Regulation of Gene_expression of Syngap1 1 0.10 0.16 0.08 5.00
171 INT304462 Binding of P2rx4 and P2rx5 1 0.17 0 0.08 5.00
172 INT254459 Ca2 Positive_regulation of Calm2 1 0.03 0 0.08 5.00
173 INT320354 IFNA1 Regulation of Cd69 1 0.01 0.2 0.07 5.00
174 INT279286 Binding of TXK and VEGFA 3 0.05 2.35 0.07 5.00
175 INT238631 Regulation of Binding of EPB41 and Cask 1 0.29 0.24 0.07 5.00
176 INT336030 PGE Regulation of Gene_expression of Cpox 1 0.05 0.22 0.07 5.00
177 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07 5.00
178 INT304456 Binding of P2rx1 and P2rx4 1 0.14 0 0.07 5.00
179 INT305205 Binding of Epo and Pbrgcsf1 1 0.14 0.23 0.07 5.00
180 INT234381 Binding of CD40 and PPARA 1 0.19 1.39 0.07 5.00
181 INT254462 Binding of Ca2 and Creb1 1 0.16 0 0.07 5.00
182 INT74033 Binding of IGHG3 and Ighg1 2 0.08 0.87 0.06 5.00
183 INT281303 Binding of Stx2 and Tlr4 1 0.11 0.09 0.06 5.00
184 INT254463 Binding of Camk2a and Cacna1c 1 0.00 0.17 0.06 5.00
185 INT325769 Binding of EPOR and Positive_regulation of Phosphorylation of JAK2 1 0.66 0 0.06 5.00
186 INT231300 Positive_regulation of Grin2b Positive_regulation of Prnp 1 0.39 0.16 0.05 5.00
187 INT336032 tf Positive_regulation of Gene_expression of Cpox 1 0.05 0.09 0.05 5.00
188 INT238619 Binding of Apba1 and Regulation of Localization of Grin2d 1 0.01 0 0.05 5.00
189 INT336031 tf Positive_regulation of Gene_expression of PGE 1 0.12 0.09 0.05 5.00
190 INT231299 Prnp Regulation of Grin2d 1 0.28 0 0.05 5.00
191 INT326253 Prkaca Negative_regulation of ARAF 1 0.00 0 0.05 5.00
192 INT282140 Ephb1 Regulation of Grip2 1 0.00 0 0.05 5.00
193 INT326251 Prkaca Positive_regulation of ARAF 1 0.00 0 0.05 5.00
194 INT338019 Egf Positive_regulation of AR 1 0.07 1.02 0.05 5.00
195 INT326250 Prkcg Positive_regulation of ARAF 1 0.00 0 0.05 5.00
196 INT320353 IFNA1 Positive_regulation of Gene_expression of Ighg2b 1 0.02 0 0.05 5.00
197 INT231302 Binding of Grin2d and Prnp 1 0.38 0.11 0.05 5.00
198 INT170517 Binding of Ryr1 and Qdpr 2 0.15 0.36 0.05 5.00
199 INT304457 Ass1 Positive_regulation of Transcription of P2rx4 1 0.01 0 0.05 5.00
200 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Myelodysplastic Syndromes. They are ordered first by their pain relevance and then by number of times they were reported in Myelodysplastic Syndromes. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT175035 Gene_expression of Mecom 11 0.65 10.1 0.19 100.00
2 INT174100 Gene_expression of YWHAE 14 0.31 12.42 0.08 100.00
3 INT117349 Binding of Mecom 4 0.31 5.38 0.32 100.00
4 INT155596 Regulation of Mecom 2 0.23 1.5 0.37 100.00
5 INT284991 Localization of YWHAE 1 0.06 3.22 0 100.00
6 INT157844 Localization of Mecom 3 0.63 2.22 0.19 100.00
7 INT273677 Gene_expression of ACACB 15 0.67 9.36 0 100.00
8 INT124061 Binding of YWHAE 3 0.30 3.43 0.4 100.00
9 INT175034 Positive_regulation of Mecom 3 0.09 3.05 0 100.00
10 INT316557 Regulation of ACACB 1 0.14 3.3 0.29 100.00
11 INT231565 Positive_regulation of YWHAE 4 0.23 3.07 0.49 100.00
12 INT284484 Positive_regulation of Gene_expression of YWHAE 3 0.23 3.4 0.08 100.00
13 INT174099 Gene_expression of RNH1 11 0.28 4.03 0.71 100.00
14 INT16959 Positive_regulation of Binding of HLA-B 8 0.50 6.77 2.96 100.00
15 INT180752 Gene_expression of PAFAH1B1 3 0.66 9.89 0.75 100.00
16 INT277763 Localization of DPM1 1 0.03 2.34 0 100.00
17 INT155595 Negative_regulation of Mecom 1 0.36 0.46 0.31 100.00
18 INT175033 Positive_regulation of Positive_regulation of Mecom 1 0.09 0.43 0 100.00
19 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 100.00
20 INT312299 Positive_regulation of Gene_expression of Mecom 1 0.03 1.9 0 100.00
21 INT45111 Gene_expression of PRB1 15 0.58 4.16 0.47 100.00
22 INT331913 Regulation of YWHAE 1 0.21 0.65 0 100.00
23 INT284974 Negative_regulation of YWHAE 1 0.04 0.59 0 100.00
24 INT9842 Binding of F2 36 0.47 22.79 4.42 100.00
25 INT150974 Binding of RNH1 3 0.35 0.87 0.1 100.00
26 INT8803 Gene_expression of IL3 32 0.78 21.06 6.01 100.00
27 INT228024 Localization of LOH19CR1 1 0.03 0.83 0 100.00
28 INT43907 Binding of CD79A 28 0.48 28.11 3.04 99.98
29 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76 99.96
30 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.96
31 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 99.96
32 INT32034 Binding of LOH19CR1 9 0.23 6.55 0.62 99.96
33 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 99.90
34 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 99.90
35 INT184063 Positive_regulation of Jak2 17 0.69 10.97 2.37 99.88
36 INT277757 Gene_expression of Pmf1 3 0.12 4.14 0.23 99.88
37 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 99.84
38 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94 99.84
39 INT200801 Positive_regulation of Localization of Src 1 0.28 1.92 0 99.84
40 INT103350 Gene_expression of DNMT1 15 0.67 9.77 3.83 99.84
41 INT201859 Positive_regulation of Gene_expression of DNMT1 4 0.60 6.43 0.75 99.84
42 INT284943 Gene_expression of DNMT3A 2 0.39 1.46 0 99.84
43 INT284947 Positive_regulation of Gene_expression of DNMT3A 2 0.25 1.29 0 99.84
44 INT312302 Gene_expression of Prss27 2 0.02 3.95 0.19 99.80
45 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14 99.80
46 INT3915 Gene_expression of SCD 25 0.57 13.94 6 99.80
47 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.76
48 INT113160 Negative_regulation of Jak2 26 0.58 20.3 2.57 99.72
49 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41 99.72
50 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 99.72
51 INT4597 Regulation of SCD 5 0.39 2.25 0.5 99.70
52 INT106483 Negative_regulation of Gene_expression of Mpl 6 0.43 5.87 0.27 99.68
53 INT17326 Binding of Plg 14 0.43 11.72 1.94 99.52
54 INT130942 Positive_regulation of Regulation of EPO 1 0.47 0.54 0.07 99.50
55 INT106484 Gene_expression of Mpl 7 0.78 20.2 16.48 99.48
56 INT8112 Regulation of EPO 38 0.58 22.04 2.76 99.48
57 INT200802 Regulation of Jak2 5 0.61 2.86 0.16 99.46
58 INT200796 Negative_regulation of Epo 7 0.43 3.22 0.18 99.44
59 INT284972 Negative_regulation of CDKN2B 3 0.44 1.13 0 99.36
60 INT200791 Binding of Mvd 1 0.13 1.5 0.03 99.36
61 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04 99.30
62 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 99.28
63 INT11686 Regulation of IL3 15 0.45 8.69 2.54 99.28
64 INT34688 Binding of CSF2RA 3 0.36 1.02 0.14 99.24
65 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 99.20
66 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37 99.20
67 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 99.20
68 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 99.20
69 INT177760 Negative_regulation of Gene_expression of IFN1@ 21 0.57 16.61 2.89 99.20
70 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 99.20
71 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16 99.12
72 INT1050 Gene_expression of hpc 21 0.58 5.33 4.2 99.12
73 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.08
74 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39 99.08
75 INT134657 Localization of Akt1 37 0.68 11.58 4.62 99.04
76 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 99.00
77 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98 99.00
78 INT244657 Regulation of Lch 3 0.40 6.63 0.13 99.00
79 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 98.96
80 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75 98.80
81 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35 98.80
82 INT310747 Regulation of JAK2 2 0.33 1.58 0.05 98.80
83 INT125832 Regulation of TTPA 3 0.05 1.33 0.08 98.80
84 INT8111 Localization of EPO 32 0.81 19.53 2.54 98.78
85 INT45503 Binding of EPO 42 0.48 24.85 2.88 98.76
86 INT127987 Regulation of Binding of EPO 3 0.45 0.6 0.1 98.76
87 INT301209 Positive_regulation of Mir29a 1 0.11 2.95 0 98.76
88 INT143912 Localization of Src 4 0.48 2.51 0.78 98.72
89 INT227468 Regulation of pk 5 0.14 1.44 0.55 98.68
90 INT277761 Gene_expression of DPM1 1 0.03 9.23 0.27 98.64
91 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45 98.56
92 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 98.52
93 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 98.52
94 INT114703 Positive_regulation of Wt1 5 0.46 4.25 0.24 98.52
95 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 98.48
96 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96 98.46
97 INT11071 Positive_regulation of PPBP 43 0.68 26.85 13.43 98.46
98 INT325790 Positive_regulation of Positive_regulation of EPOR 1 0.69 1.04 0.07 98.36
99 INT273675 Binding of ACACB 7 0.42 8.69 0.09 98.34
100 INT107948 Gene_expression of Spl 4 0.37 3.94 1.67 98.32
101 INT144702 Gene_expression of Tst 19 0.68 12.87 4.04 98.28
102 INT315796 Positive_regulation of Gene_expression of Tst 1 0.32 5 0 98.28
103 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 98.22
104 INT148291 Positive_regulation of CSF3 9 0.61 6.37 0.7 98.22
105 INT212362 Positive_regulation of Gene_expression of CSF3 3 0.32 4.85 0.26 98.22
106 INT175036 Regulation of Igk 1 0.00 1.46 0.38 98.20
107 INT277802 Gene_expression of Rit1 3 0.35 4.59 0.21 98.20
108 INT221097 Negative_regulation of Atp8a1 15 0.57 10.52 2.65 98.12
109 INT127986 Regulation of CSF3R 2 0.33 5.91 0.22 98.04
110 INT95616 Gene_expression of Thpo 48 0.78 21.51 5.88 98.04
111 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 98.00
112 INT173971 Positive_regulation of Ppia-ps 1 0.04 0.99 0 98.00
113 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03 97.96
114 INT37430 Gene_expression of Gpi1 61 0.63 54.63 13.87 97.94
115 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 97.92
116 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 97.92
117 INT102659 Gene_expression of CSF3 32 0.77 21.93 2.39 97.92
118 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41 97.88
119 INT189946 Positive_regulation of Gene_expression of Pttg1 14 0.68 23.72 0.38 97.88
120 INT178029 Gene_expression of Epo 25 0.76 14.98 1.46 97.84
121 INT145932 Gene_expression of Hck 5 0.77 2.69 0.73 97.82
122 INT90889 Positive_regulation of Rxrg 1 0.11 0.95 0 97.68
123 INT315800 Localization of Tst 11 0.54 8.09 0.73 97.66
124 INT117083 Localization of RTEL1 5 0.60 9.1 0.8 97.66
125 INT200794 Gene_expression of Fgr 1 0.54 1.18 0 97.64
126 INT3098 Positive_regulation of Epo 46 0.70 28.27 7 97.60
127 INT320830 Gene_expression of PRSS27 1 0.65 1.73 0 97.52
128 INT80696 Positive_regulation of Thpo 16 0.70 13.75 4.49 97.40
129 INT14690 Localization of CSF2 124 0.80 85.17 27.26 97.36
130 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 97.36
131 INT200797 Positive_regulation of Ptprv 4 0.14 3.19 0.58 97.36
132 INT162539 Binding of JAKMIP2 1 0.02 1.07 0 97.36
133 INT146943 Gene_expression of Src 13 0.49 6.65 1.65 97.14
134 INT325780 Positive_regulation of EPOR 1 0.69 2.86 0.36 97.12
135 INT200787 Negative_regulation of Fgr 1 0.52 1.01 0 97.12
136 INT325789 Negative_regulation of Positive_regulation of EPOR 1 0.43 0.35 0 97.12
137 INT186882 Gene_expression of RTEL1 13 0.27 13.45 0.49 97.00
138 INT1049 Positive_regulation of hpc 18 0.40 3.16 8.45 96.98
139 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 96.92
140 INT132938 Phosphorylation of Insrr 21 0.03 10.55 8.88 96.84
141 INT110445 Phosphorylation of Gtf3a 15 0.09 5.58 3.07 96.84
142 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43 96.84
143 INT51646 Binding of IL3 3 0.37 3.26 0.56 96.84
144 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 96.80
145 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 96.80
146 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 96.76
147 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 96.76
148 INT200789 Negative_regulation of Hck 1 0.53 1.01 0 96.76
149 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 96.60
150 INT108723 Negative_regulation of Thpo 5 0.59 3.26 0.51 96.60
151 INT313929 Negative_regulation of Negative_regulation of Thpo 1 0.39 0.54 0.17 96.60
152 INT15742 Negative_regulation of EPO 37 0.59 17.44 1.84 96.56
153 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95 96.56
154 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 96.48
155 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17 96.48
156 INT19107 Positive_regulation of Tbxa2r 23 0.62 12.54 8.44 96.38
157 INT87699 Positive_regulation of WAS 16 0.45 5.84 8.03 96.32
158 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.08
159 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 96.08
160 INT121788 Localization of BCS1L 11 0.73 10.16 1.14 96.00
161 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 95.84
162 INT59286 Regulation of Gene_expression of EPO 7 0.62 6.13 0.13 95.80
163 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2 95.68
164 INT53433 Gene_expression of Igk 8 0.75 1.34 4.18 95.68
165 INT111609 Gene_expression of CTNNA1 3 0.46 3.2 0.57 95.64
166 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98 95.60
167 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7 95.52
168 INT200792 Regulation of Gene_expression of Jak2 5 0.61 5.69 0.09 95.48
169 INT245123 Gene_expression of CDKN2B 6 0.68 3.62 0.07 95.48
170 INT284970 Positive_regulation of Gene_expression of CDKN2B 1 0.61 0.55 0 95.48
171 INT192748 Localization of BCR 4 0.68 2.4 0.18 95.36
172 INT241506 Localization of Abl1 2 0.54 2.37 0.04 95.28
173 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 95.12
174 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 95.12
175 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28 95.12
176 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34 95.08
177 INT151413 Negative_regulation of FNTA 3 0.10 1.33 0.19 95.02
178 INT163489 Binding of CDH1 13 0.19 8.63 0.35 95.00
179 INT184989 Positive_regulation of CDKN2B 3 0.47 2.77 0.07 94.84
180 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 94.60
181 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 94.40
182 INT312354 Regulation of Gene_expression of JAK2 1 0.25 1.17 0.1 94.40
183 INT2843 Gene_expression of Epo 100 0.78 62.01 14.66 94.32
184 INT60685 Positive_regulation of Gene_expression of Epo 21 0.53 15.86 1.25 94.32
185 INT307906 Negative_regulation of Transcription of Wt1 1 0.54 1.3 0 94.28
186 INT142404 Gene_expression of THPO 18 0.77 4.39 0.56 94.20
187 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17 94.16
188 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81 94.08
189 INT284939 Binding of RUNX1T1 1 0.36 1.19 0 94.08
190 INT303972 Positive_regulation of Gene_expression of JAK2 2 0.63 1.3 0.24 94.08
191 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 94.00
192 INT24926 Regulation of Csf3 17 0.52 10.41 3.04 93.88
193 INT276550 Transcription of Wt1 2 0.66 1.35 0 93.80
194 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 93.36
195 INT224335 Negative_regulation of Phosphorylation of KDR 5 0.35 5.24 0.09 93.36
196 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 93.36
197 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22 93.28
198 INT98456 Negative_regulation of Src 17 0.42 8.3 0.42 93.20
199 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 93.12
200 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 93.04
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