D:Myocardial Reperfusion Injury

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Injuries Myocardial Reperfusion, INJURY MYOCARDIAL REPERFUSION, Myocardial Ischemic Reperfusion Injury, Myocardial Reperfusion Injuries, Reperfusion Injuries Myocardial, Reperfusion Injury Myocardial
Documents 20
Hot Single Events 21
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Myocardial Reperfusion Injury. They are ordered first by their relevance to Myocardial Reperfusion Injury and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2 99.46
2 INT285982 Ros1 Positive_regulation of Binding of Trib3 1 0.02 1.41 0.08 99.46
3 INT289530 Sirt1 Regulation of Foxo1 1 0.25 0.42 0 57.12
4 INT285981 Ros1 Regulation of Positive_regulation of Trib3 1 0.01 0.95 0.12 50.00
5 INT175985 Igf1 Positive_regulation of Gene_expression of Serpina1c 1 0.14 0.55 0.11 27.08
6 INT175987 Igf1 Positive_regulation of Serpina1c 1 0.13 0.54 0.11 27.08
7 INT175984 Igf1 Regulation of Localization of Serpina1c 1 0.14 0.54 0.08 24.08
8 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71 5.00
9 INT175988 Ros1 Positive_regulation of Transcription of Gtf3a 1 0.01 1.56 0.34 5.00
10 INT175990 Ros1 Positive_regulation of Gene_expression of Gtf3a 1 0.01 1.56 0.34 5.00
11 INT348059 Dbi Negative_regulation of Binding of Mpo 1 0.08 0.43 0.19 5.00
12 INT175991 Binding of VEGFA and Igf1 1 0.04 0.57 0.17 5.00
13 INT293712 Binding of Adra2a and Atl1 1 0.06 0.83 0.15 5.00
14 INT175992 TNF Positive_regulation of Gene_expression of Cys1 1 0.01 0.34 0.07 5.00
15 INT352368 MIR20B Regulation of VEGFA 1 0.08 0.44 0.04 5.00
16 INT352385 MIR27A Regulation of Foxo1 1 0.45 0.48 0.04 5.00
17 INT352381 Mir21 Regulation of Ephb1 1 0.02 0 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Myocardial Reperfusion Injury. They are ordered first by their pain relevance and then by number of times they were reported in Myocardial Reperfusion Injury. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.84
2 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 99.76
3 INT91374 Negative_regulation of Gene_expression of Nfkb1 12 0.58 5.06 1.75 99.76
4 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 99.66
5 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58 99.20
6 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.20
7 INT50704 Binding of Trib3 13 0.31 6.33 5.46 98.32
8 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97 98.20
9 INT55342 Negative_regulation of Gene_expression of Ros1 49 0.37 31.62 8.93 98.20
10 INT352373 Regulation of Mir21 1 0.04 0.45 0 95.72
11 INT48924 Positive_regulation of Mapk3 107 0.67 50.53 34.05 95.36
12 INT57424 Positive_regulation of TNNT1 42 0.67 31.84 9.7 94.48
13 INT143646 Negative_regulation of Mapk8ip1 5 0.03 5.46 1.28 93.40
14 INT53684 Negative_regulation of Gene_expression of ITGAM 23 0.59 14.36 5.66 90.88
15 INT53683 Negative_regulation of Gene_expression of ITGB2 10 0.57 9.11 3.2 90.88
16 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8 87.36
17 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 83.36
18 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 83.36
19 INT64792 Positive_regulation of Gene_expression of ITGAM 39 0.69 23.21 6.71 83.36
20 INT70326 Positive_regulation of Gene_expression of ITGB2 24 0.67 15.42 3.86 83.36
21 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 80.12
22 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 75.00
23 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 75.00
24 INT1216 Negative_regulation of Pde4b 9 0.41 2.65 2.5 75.00
25 INT79402 Gene_expression of Pde4b 7 0.74 3 2.38 75.00
26 INT166628 Positive_regulation of Gene_expression of Becn1 2 0.67 1.03 1.23 75.00
27 INT166632 Gene_expression of Becn1 2 0.75 1.02 1.22 75.00
28 INT168569 Binding of Anxa3 1 0.36 0.53 0.34 75.00
29 INT58116 Negative_regulation of Amh 2 0.31 0.55 0.25 75.00
30 INT58117 Transcription of Amh 1 0.17 0.37 0.24 75.00
31 INT79487 Negative_regulation of Gene_expression of Pde4b 1 0.07 0.65 0.04 75.00
32 INT127363 Binding of Cpb1 8 0.32 2.5 1.14 74.96
33 INT352377 Positive_regulation of Sirt4 1 0.36 1.64 0.04 70.08
34 INT352376 Positive_regulation of Sirt3 1 0.37 1.64 0.04 69.28
35 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56 66.92
36 INT156093 Negative_regulation of Positive_regulation of Ros1 8 0.23 5.17 2.03 66.92
37 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 66.36
38 INT276173 Phosphorylation of Foxo1 7 0.56 1.79 0.15 65.92
39 INT50512 Negative_regulation of Binding of Mpo 2 0.43 2.11 0.61 62.56
40 INT348053 Negative_regulation of Localization of Ccl3 1 0.01 0.98 0.33 62.56
41 INT25634 Binding of Mpo 21 0.48 14.78 4.39 62.16
42 INT121952 Localization of Ccl3 2 0.05 1.95 0.67 61.60
43 INT276188 Negative_regulation of Foxo1 5 0.40 1.75 0.23 58.88
44 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 50.00
45 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92 50.00
46 INT38253 Localization of Trib3 35 0.63 10.28 15.42 50.00
47 INT55343 Localization of Ros1 39 0.60 34.51 12.5 50.00
48 INT38254 Positive_regulation of Localization of Trib3 14 0.45 6.14 6.99 50.00
49 INT48926 Positive_regulation of Gene_expression of Mapk3 12 0.46 6.02 6.13 50.00
50 INT115528 Binding of Ros1 37 0.41 22.96 5.5 50.00
51 INT133085 Gene_expression of Mapk8ip1 7 0.66 6.13 2.98 50.00
52 INT217267 Positive_regulation of Binding of Ros1 6 0.27 3.08 0.15 50.00
53 INT285978 Negative_regulation of Gene_expression of Mapk8ip1 1 0.01 0.66 0.04 50.00
54 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 38.80
55 INT232589 Positive_regulation of Serpina5 4 0.19 0.8 0.09 38.16
56 INT12563 Localization of Mpo 33 0.81 20.99 9.58 33.60
57 INT72380 Positive_regulation of Shc1 10 0.69 6.87 0.77 32.16
58 INT22405 Positive_regulation of Crk 2 0.09 0.64 0.23 31.96
59 INT96258 Positive_regulation of Pik3cd 14 0.43 8.74 5.16 30.80
60 INT22784 Positive_regulation of Serpina1c 3 0.20 1.11 0.6 30.80
61 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04 30.56
62 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 27.76
63 INT175971 Gene_expression of Serpina1c 1 0.17 0.54 0.11 26.32
64 INT175969 Localization of Serpina1c 1 0.22 0.49 0.08 24.08
65 INT65263 Positive_regulation of Gene_expression of Igf1 61 0.69 25.69 14.49 14.88
66 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 12.96
67 INT203007 Regulation of Cpb1 4 0.39 1.17 0.23 10.80
68 INT7608 Positive_regulation of Adra2a 66 0.70 17.81 35.15 5.44
69 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
70 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
71 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
72 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
73 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
74 INT63934 Phosphorylation of Ephb1 377 0.82 150.52 188.66 5.00
75 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
76 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
77 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 5.00
78 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
79 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 5.00
80 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 5.00
81 INT63936 Positive_regulation of Phosphorylation of Ephb1 131 0.70 49.38 73.16 5.00
82 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 5.00
83 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
84 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
85 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
86 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 5.00
87 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
88 INT97702 Positive_regulation of Phosphorylation of Mapk14 69 0.69 49.21 36.81 5.00
89 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03 5.00
90 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 5.00
91 INT5988 Localization of Dbi 74 0.81 17.52 24.09 5.00
92 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 5.00
93 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
94 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
95 INT3030 Gene_expression of Adra2a 37 0.68 5.58 19.76 5.00
96 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2 5.00
97 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75 5.00
98 INT65661 Positive_regulation of Ado 13 0.52 4.75 8.54 5.00
99 INT30638 Positive_regulation of Gene_expression of Dbi 17 0.69 4.63 8.28 5.00
100 INT101189 Transcription of Gtf3a 49 0.17 24.39 7.93 5.00
101 INT217186 Gene_expression of MIR155 26 0.48 29.45 7.92 5.00
102 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94 5.00
103 INT20343 Positive_regulation of Localization of Dbi 21 0.63 5.01 6.61 5.00
104 INT151032 Localization of Igf1 49 0.76 26.32 5.71 5.00
105 INT126047 Regulation of Phosphorylation of Mapk14 7 0.60 5.05 5.03 5.00
106 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 5.00
107 INT15239 Regulation of Junb 13 0.62 1.14 4.1 5.00
108 INT68189 Gene_expression of TNNT1 27 0.75 14.87 4.03 5.00
109 INT88805 Protein_catabolism of CASP3 24 0.86 18.38 3.7 5.00
110 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19 5.00
111 INT31923 Positive_regulation of Positive_regulation of Adra2a 7 0.44 1.88 2.89 5.00
112 INT84811 Gene_expression of Ado 6 0.51 2.65 2.74 5.00
113 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58 5.00
114 INT4686 Gene_expression of Cys1 32 0.66 36.24 2.49 5.00
115 INT88225 Transcription of Ugt1a1 5 0.61 1.51 2.4 5.00
116 INT14586 Gene_expression of Cpb1 23 0.58 6.18 1.99 5.00
117 INT318449 Gene_expression of Mir21 18 0.37 11.92 1.46 5.00
118 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41 5.00
119 INT90491 Binding of Igf1 25 0.44 9.75 1.36 5.00
120 INT318448 Positive_regulation of Gene_expression of Mir21 11 0.33 6.31 1.12 5.00
121 INT217167 Negative_regulation of Gene_expression of MIR155 4 0.23 3.43 0.91 5.00
122 INT84810 Positive_regulation of Positive_regulation of Ado 2 0.35 0.36 0.9 5.00
123 INT318440 Positive_regulation of Mir21 10 0.33 5.93 0.86 5.00
124 INT1939 Localization of Cys1 6 0.73 5.9 0.64 5.00
125 INT38479 Positive_regulation of Kcne2 4 0.40 1 0.63 5.00
126 INT49302 Localization of TNNT2 6 0.78 3.1 0.34 5.00
127 INT66776 Negative_regulation of Kcne2 6 0.35 2.48 0.33 5.00
128 INT288041 Negative_regulation of Positive_regulation of TNNT1 1 0.41 0.15 0.32 5.00
129 INT297904 Positive_regulation of Foxo3 6 0.57 8.19 0.29 5.00
130 INT214664 Gene_expression of Serpina5 6 0.26 2.91 0.22 5.00
131 INT175973 Negative_regulation of Serpina1c 2 0.17 1.93 0.2 5.00
132 INT75557 Regulation of Jund 4 0.52 0.96 0.2 5.00
133 INT16090 Negative_regulation of Cpb1 4 0.36 0.51 0.14 5.00
134 INT284805 Negative_regulation of Localization of TNNT2 1 0.42 0.77 0.13 5.00
135 INT175970 Negative_regulation of Phosphorylation of Igf1 2 0.39 2.1 0.13 5.00
136 INT210032 Binding of Serpina5 4 0.18 1.87 0.12 5.00
137 INT175968 Phosphorylation of Igf1 6 0.74 2.54 0.1 5.00
138 INT298659 Gene_expression of MIR27A 2 0.65 1.19 0.09 5.00
139 INT318442 Negative_regulation of Mir21 5 0.24 4.6 0.09 5.00
140 INT352374 Gene_expression of Mir101a 1 0.13 0 0.09 5.00
141 INT352379 Gene_expression of Mir667 1 0.15 0 0.08 5.00
142 INT175972 Regulation of Phosphorylation of Igf1 1 0.41 0.95 0.07 5.00
143 INT352375 Positive_regulation of Nampt 1 0.21 1.32 0.05 5.00
144 INT352378 Positive_regulation of Negative_regulation of Mir21 1 0.08 0.64 0.04 5.00
145 INT289592 Positive_regulation of Foxo1 2 0.41 1.44 0.04 5.00
146 INT352384 Regulation of MIR539 1 0.26 0 0.04 5.00
147 INT185732 Transcription of Tnfrsf11b 2 0.31 0.39 0.03 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox