D:Myofascial Pain Syndromes

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Disease Term
Synonyms MYOFASCIAL PAIN SYNDROME, Myofascial Trigger Point, Myofascial Trigger Points, PAIN SYNDROME MYOFASCIAL, PAIN SYNDROMES MYOFASCIAL, Syndrome Myofascial Pain, Syndromes Myofascial Pain, Trigger Point Myofascial, Trigger Points Myofascial
Documents 559
Hot Single Events 39
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Myofascial Pain Syndromes. They are ordered first by their relevance to Myofascial Pain Syndromes and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17 93.56
2 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85 66.32
3 INT351322 Nts Regulation of Localization of Napa 1 0.01 0.56 0.77 60.40
4 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 46.32
5 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 5.00
6 INT346986 Binding of SHC3 and PAG1 1 0.35 1.02 1.12 5.00
7 INT204943 Il6 Regulation of Slc39a14 1 0.00 0.54 0.36 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Myofascial Pain Syndromes. They are ordered first by their pain relevance and then by number of times they were reported in Myofascial Pain Syndromes. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 100.00
2 INT57957 Localization of TXNRD1 14 0.64 4.01 2.7 100.00
3 INT39507 Positive_regulation of TXNRD1 37 0.68 12.47 14.25 100.00
4 INT47540 Binding of Cp 20 0.41 15.54 7.01 100.00
5 INT69951 Binding of Cgnz1 3 0.25 1.82 1.64 100.00
6 INT137961 Localization of Ppt1 1 0.64 2.89 3.09 99.52
7 INT158279 Regulation of Myst2 2 0.37 0.51 0.65 99.48
8 INT47909 Binding of CPP 32 0.48 24.9 13.79 99.38
9 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 99.24
10 INT71350 Positive_regulation of Tpnr1 3 0.01 3.92 4.08 98.68
11 INT138254 Regulation of Positive_regulation of Laptm4a 1 0.15 0.46 0.46 98.60
12 INT138253 Positive_regulation of Laptm4a 1 0.23 0.46 0.46 98.60
13 INT4652 Gene_expression of CB 13 0.32 7.41 5.57 98.08
14 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 98.08
15 INT157962 Positive_regulation of LAPTM4A 1 0.33 1.03 0.79 96.68
16 INT9643 Negative_regulation of Actvty1 7 0.07 5.54 3.31 96.68
17 INT262375 Binding of Fmod 1 0.20 12.37 10.1 96.24
18 INT1316 Positive_regulation of Acot1 129 0.60 18.86 56.13 95.64
19 INT3766 Positive_regulation of Localization of Acot1 192 0.69 21.8 85.35 95.28
20 INT1352 Localization of Acot1 728 0.80 73.01 296.01 95.28
21 INT41727 Negative_regulation of Localization of Nts 3 0.39 1.48 3.15 95.22
22 INT15044 Localization of Nts 30 0.75 4.58 13.72 94.60
23 INT2330 Regulation of CB 78 0.10 20.46 32.6 93.84
24 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 93.56
25 INT108535 Positive_regulation of TNNI1 7 0.67 5.54 2.12 93.44
26 INT48120 Positive_regulation of Cacna1h 5 0.34 1.2 2.22 93.28
27 INT256655 Positive_regulation of Psma1 1 0.20 0.8 1.45 92.08
28 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 92.04
29 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 91.60
30 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41 91.60
31 INT24196 Positive_regulation of Binding of Chrna7 8 0.45 0.79 2.13 91.28
32 INT626 Localization of CALCA 289 0.81 125.39 221.15 90.40
33 INT166490 Localization of Msn 9 0.80 0.61 2.32 89.96
34 INT7134 Localization of KNG1 127 0.79 65.73 67.97 88.32
35 INT58258 Regulation of sea 5 0.39 0.63 0.6 87.96
36 INT33857 Negative_regulation of NTS 6 0.42 4.98 3.07 87.84
37 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 87.28
38 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1 86.40
39 INT44246 Positive_regulation of Sts 9 0.43 6.19 0.45 81.68
40 INT11937 Localization of Il6 228 0.81 139.83 64.39 78.16
41 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 78.16
42 INT3559 Negative_regulation of Localization of Gnrhr 73 0.58 18.89 26.41 78.16
43 INT158278 Positive_regulation of Myst2 2 0.41 0.89 1.02 77.92
44 INT142234 Gene_expression of CLINT1 2 0.58 0.75 0.03 75.24
45 INT5774 Regulation of Ppt1 22 0.60 4.97 7.1 75.00
46 INT165258 Binding of BC013712 1 0.06 0.85 1.02 75.00
47 INT4729 Positive_regulation of PPT1 19 0.67 7.11 17.83 75.00
48 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4 75.00
49 INT55353 Negative_regulation of Positive_regulation of Ppt1 9 0.57 0.31 5.37 75.00
50 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 75.00
51 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 74.96
52 INT92966 Positive_regulation of FGF1 4 0.38 2.25 1.33 73.12
53 INT2649 Regulation of Calca 433 0.62 146.05 330.95 71.60
54 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 68.84
55 INT3167 Binding of KNG1 48 0.48 23.26 26.77 68.84
56 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 67.80
57 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37 66.64
58 INT5008 Localization of Calca 204 0.81 80.35 125.16 66.32
59 INT7056 Positive_regulation of Gene_expression of PENK 35 0.70 14.31 18.21 64.96
60 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 63.76
61 INT109559 Localization of Napa 16 0.61 1.3 2.42 60.40
62 INT2339 Positive_regulation of CB 30 0.29 10.68 9.12 55.04
63 INT15508 Negative_regulation of nt 8 0.36 3.4 2.26 54.64
64 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 52.80
65 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 52.80
66 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98 52.80
67 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67 52.52
68 INT71762 Negative_regulation of sea 6 0.36 1.73 1.86 52.20
69 INT9798 Negative_regulation of Gene_expression of Homer1 10 0.41 2.04 3.77 51.52
70 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 50.00
71 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83 50.00
72 INT104441 Binding of NOVA2 72 0.42 16.41 10.51 50.00
73 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98 50.00
74 INT49027 Gene_expression of TYRP1 35 0.75 9.81 6.06 50.00
75 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27 50.00
76 INT77562 Regulation of TNS3 5 0.39 1 0.55 50.00
77 INT166491 Regulation of Localization of Msn 1 0.45 0 0 50.00
78 INT51150 Positive_regulation of HTC2 10 0.67 6.8 2.95 46.08
79 INT316829 Negative_regulation of SYNM 4 0.54 3.31 3.32 34.80
80 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25 27.92
81 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86 26.72
82 INT169387 Regulation of Gene_expression of Chrna7 4 0.36 2.19 1.63 25.68
83 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 22.96
84 INT274527 Regulation of SYNM 3 0.20 2.68 2.7 21.92
85 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
86 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
87 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
88 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
89 INT81417 Gene_expression of PAG1 94 0.58 90.85 92.79 5.00
90 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
91 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 5.00
92 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 5.00
93 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
94 INT8048 Gene_expression of Nts 45 0.74 8.9 21.84 5.00
95 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 5.00
96 INT99058 Regulation of PAG1 18 0.45 21.62 18.5 5.00
97 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25 5.00
98 INT132335 Gene_expression of KCNA1 36 0.77 18.31 13.36 5.00
99 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
100 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62 5.00
101 INT20457 Regulation of Ptgs1 23 0.48 11.63 11.56 5.00
102 INT45812 Protein_catabolism of Gabrg1 12 0.79 1.93 8.76 5.00
103 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98 5.00
104 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 5.00
105 INT79168 Binding of TNC 39 0.47 16.51 7.55 5.00
106 INT15812 Localization of CALCB 10 0.30 8.77 6.36 5.00
107 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27 5.00
108 INT9567 Binding of Nts 10 0.44 2.14 5.89 5.00
109 INT46152 Positive_regulation of CYP4F22 7 0.46 4.05 5.56 5.00
110 INT62336 Positive_regulation of Hdc 38 0.70 14.45 5.51 5.00
111 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08 5.00
112 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 5.00
113 INT117204 Gene_expression of Tcm 39 0.58 10.58 4.88 5.00
114 INT140350 Binding of C2 17 0.36 3.97 4.69 5.00
115 INT190833 Regulation of KCNA1 8 0.53 6.61 4.66 5.00
116 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92 5.00
117 INT15814 Positive_regulation of Localization of CALCB 4 0.20 2.49 3.82 5.00
118 INT122051 Negative_regulation of ROM1 17 0.48 9.11 3.38 5.00
119 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
120 INT82913 Regulation of Ppara 15 0.61 10.66 3.03 5.00
121 INT68444 Gene_expression of CPE 9 0.76 4.6 2.59 5.00
122 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56 5.00
123 INT204019 Negative_regulation of C2 10 0.26 6.23 2.44 5.00
124 INT29094 Binding of C3 39 0.37 12.65 2.27 5.00
125 INT177598 Regulation of C7orf49 7 0.14 2.23 2.23 5.00
126 INT219682 Gene_expression of CYP4F22 3 0.75 0.97 2.2 5.00
127 INT105824 Regulation of Casq1 4 0.07 2.66 2.1 5.00
128 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 5.00
129 INT47425 Localization of Chrna7 11 0.81 6.7 1.86 5.00
130 INT162666 Gene_expression of ST3 5 0.67 5.66 1.73 5.00
131 INT167847 Positive_regulation of Gene_expression of Chrna7 7 0.49 3.02 1.57 5.00
132 INT297413 Gene_expression of Koa 2 0.22 1.88 1.37 5.00
133 INT157778 Localization of CYP4F22 2 0.73 0.35 1.15 5.00
134 INT245200 Protein_catabolism of Koa 2 0.29 1.69 0.93 5.00
135 INT175904 Localization of RAC1 7 0.41 5.05 0.86 5.00
136 INT138307 Regulation of Tcm 15 0.39 4.1 0.81 5.00
137 INT262373 Positive_regulation of Fmod 1 0.20 0.89 0.77 5.00
138 INT212265 Positive_regulation of Gene_expression of CPE 1 0.44 1.26 0.7 5.00
139 INT336708 Gene_expression of Lynx1 2 0.49 1.72 0.67 5.00
140 INT351321 Binding of Lynx1 1 0.01 0.87 0.63 5.00
141 INT323378 Positive_regulation of Koa 1 0.17 1.02 0.56 5.00
142 INT178222 Gene_expression of Yy1 5 0.57 2.06 0.56 5.00
143 INT323377 Positive_regulation of Protein_catabolism of Koa 1 0.17 1.01 0.53 5.00
144 INT323379 Gene_expression of SP9 1 0.43 1.11 0.46 5.00
145 INT282111 Negative_regulation of Gvhd1 4 0.22 2.96 0.44 5.00
146 INT204941 Protein_catabolism of Timp2 1 0.03 0.35 0.32 5.00
147 INT257954 Regulation of FGF7 2 0.45 0.52 0.32 5.00
148 INT209076 Negative_regulation of PSME3 2 0.34 0.86 0.21 5.00
149 INT209077 Positive_regulation of Negative_regulation of PSME3 1 0.37 0.13 0.19 5.00
150 INT209075 Negative_regulation of Fhl1 1 0.01 0.13 0.18 5.00
151 INT166811 Regulation of Casq1 3 0.04 1.18 0.1 5.00
152 INT204938 Positive_regulation of Casq1 1 0.08 0.17 0.03 5.00
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