D:Myoglobinuria

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Disease Term
Synonyms Myoglobinurias
Documents 172
Hot Single Events 51
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Myoglobinuria. They are ordered first by their relevance to Myoglobinuria and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT111380 Musk Negative_regulation of Phka2 1 0.03 0.92 0.19 94.48
2 INT3488 Binding of CPT2 and CPT1C 1 0.13 0.57 0.19 93.80
3 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 63.92
4 INT205589 Binding of PPT2 and COQ2 1 0.04 1.02 0.07 60.32
5 INT205588 Binding of SNRNP70 and PPT2 1 0.03 0.26 0 5.72
6 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
7 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14 5.00
8 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14 5.00
9 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
10 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 5.00
11 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00
12 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
13 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
14 INT283226 Binding of ACE and CC2D1A 1 0.11 2.37 0.04 5.00
15 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
16 INT315034 Ass1 Positive_regulation of Cacna1f 1 0.00 0 0.03 5.00
17 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0 5.00
18 INT312956 Regulation of Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
19 INT315033 Binding of Calm3 and Vsig2 1 0.00 0 0 5.00
20 INT315541 ACO1 Negative_regulation of Gene_expression of ALAS2 1 0.17 0.18 0 5.00
21 INT315534 Binding of ACO1 and ERN1 1 0.01 0.18 0 5.00
22 INT315029 Binding of Calm3 and Cacna1f 1 0.04 0 0 5.00
23 INT312955 Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
24 INT315535 Binding of ABCB7 and FECH 1 0.28 0.7 0 5.00
25 INT315533 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of ALAS2 1 0.38 1.06 0 5.00
26 INT315035 Binding of NAE1 and Cav1 1 0.01 0.7 0 5.00
27 INT315031 Binding of Cacna1f and Vsig2 1 0.02 0 0 5.00
28 INT315532 Binding of NFS1 and ISCU 1 0.19 0.37 0 5.00
29 INT315538 Negative_regulation of GLRX5 Negative_regulation of Gene_expression of SLC40A1 1 0.25 1.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Myoglobinuria. They are ordered first by their pain relevance and then by number of times they were reported in Myoglobinuria. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 99.90
2 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36 99.88
3 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 99.88
4 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 99.84
5 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 99.76
6 INT20650 Positive_regulation of F2 26 0.69 15.49 5.08 99.72
7 INT93956 Binding of HBM 20 0.35 8.86 1.48 99.24
8 INT80857 Negative_regulation of Cpt2 19 0.42 12.1 1.6 99.12
9 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 99.12
10 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 99.04
11 INT2395 Binding of MB 18 0.36 7.53 0.68 98.68
12 INT69947 Negative_regulation of MTAP 5 0.40 2.63 0.48 98.00
13 INT16184 Negative_regulation of CHKB 20 0.53 10.61 1.42 97.80
14 INT312973 Binding of ACADVL 1 0.23 2.35 0.17 97.76
15 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 97.52
16 INT3491 Negative_regulation of CPT2 8 0.57 4.32 0.62 97.44
17 INT58917 Negative_regulation of Zdhhc7 2 0.51 1.06 0.08 97.04
18 INT131527 Negative_regulation of Acadvl 9 0.56 3.17 0.81 96.08
19 INT28894 Positive_regulation of PLK2 3 0.50 3.77 0.69 96.08
20 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1 95.84
21 INT273279 Negative_regulation of Localization of Tmie 2 0.07 1.72 0.2 95.84
22 INT11737 Negative_regulation of Ampd1 2 0.13 1.26 0.18 95.84
23 INT102231 Localization of HBM 8 0.60 6.14 0.88 95.40
24 INT170507 Localization of Tmie 27 0.43 6.25 1.31 95.32
25 INT17561 Localization of Car2 303 0.79 60.95 44.52 95.20
26 INT82857 Negative_regulation of ACOT8 3 0.19 1.1 0.25 94.96
27 INT66797 Positive_regulation of Transcription of PHKG1 1 0.26 0.28 0.1 94.84
28 INT66796 Transcription of PHKG1 1 0.36 0.28 0.1 94.84
29 INT111379 Negative_regulation of Phka2 1 0.41 0.92 0.19 94.48
30 INT74630 Negative_regulation of ACADVL 8 0.58 2.49 0.53 91.56
31 INT24800 Negative_regulation of AMPD1 44 0.59 21.19 6.76 91.48
32 INT2442 Localization of Mb 38 0.80 24.74 6.33 90.96
33 INT107777 Phosphorylation of AGL 3 0.54 2.45 0.09 90.88
34 INT107776 Negative_regulation of Phosphorylation of AGL 1 0.37 0.99 0.09 90.88
35 INT35745 Negative_regulation of AGL 29 0.50 9.16 2.03 89.76
36 INT138843 Binding of CC2D1A 19 0.33 33.06 1.25 88.24
37 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 87.12
38 INT36413 Regulation of NMS 2 0.23 1.97 0.27 86.32
39 INT11367 Localization of MB 9 0.78 9.34 1.24 86.24
40 INT9140 Negative_regulation of PFKM 14 0.59 12.67 3.61 85.60
41 INT156776 Regulation of Slc22a12 3 0.25 1.74 0.4 85.28
42 INT53447 Negative_regulation of DLD 17 0.54 12.9 2.48 84.84
43 INT5262 Positive_regulation of AGL 14 0.40 7.51 0.65 84.48
44 INT205597 Positive_regulation of PPT2 1 0.05 0.43 0 84.04
45 INT250743 Localization of CC2D1A 12 0.51 20.97 0.51 83.76
46 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 83.40
47 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 83.40
48 INT4664 Positive_regulation of Ampd1 3 0.41 0.93 0.37 82.68
49 INT58908 Positive_regulation of Negative_regulation of AMPD1 2 0.44 0.86 0.17 82.24
50 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 80.80
51 INT3492 Negative_regulation of CPT1A 2 0.39 0.24 0.08 80.76
52 INT11365 Positive_regulation of Localization of Mb 5 0.38 3.78 1.54 79.92
53 INT156777 Localization of Slc22a12 1 0.70 0.78 0.18 79.64
54 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78 78.64
55 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97 77.84
56 INT98609 Negative_regulation of PYGM 11 0.43 6.21 0.6 77.64
57 INT205599 Binding of PPT2 1 0.04 0.74 0 77.16
58 INT220506 Binding of Cav1 13 0.45 5.46 0.38 76.96
59 INT16131 Negative_regulation of GBE1 37 0.30 10.32 8.15 75.00
60 INT3490 Gene_expression of CPT1A 2 0.51 0.22 0.07 74.52
61 INT25170 Positive_regulation of Localization of Car2 78 0.67 15.25 11.24 71.92
62 INT112328 Negative_regulation of PHKG1 2 0.46 0.83 0.1 71.92
63 INT170503 Positive_regulation of Localization of Tmie 11 0.29 3.27 0.61 71.60
64 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 69.84
65 INT315005 Binding of Hmgcs2 1 0.11 0.73 0.11 69.80
66 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 69.40
67 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 67.44
68 INT205594 Gene_expression of COQ10A 19 0.67 12.53 2.56 63.32
69 INT97453 Negative_regulation of MOCS1 25 0.04 13.4 2.4 62.56
70 INT205592 Negative_regulation of Gene_expression of COQ10A 7 0.37 5.98 1.54 57.92
71 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 57.44
72 INT135720 Gene_expression of War 7 0.34 3.99 0.28 54.56
73 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 52.72
74 INT205595 Gene_expression of PPT2 1 0.05 0 0 49.24
75 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66 48.56
76 INT315009 Regulation of Phosphorylation of Cav1 1 0.36 0.2 0.05 46.84
77 INT4210 Gene_expression of MB 24 0.78 11.74 2.32 46.48
78 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22 46.24
79 INT174848 Gene_expression of ISCU 2 0.59 2.79 0.08 46.16
80 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22 45.32
81 INT108156 Positive_regulation of MAPKAP1 4 0.08 1.91 1.14 41.88
82 INT68446 Negative_regulation of Cpt1a 5 0.38 6.5 0.56 41.60
83 INT308161 Negative_regulation of CPT1B 1 0.08 0.46 0 41.60
84 INT18396 Positive_regulation of Ryr1 10 0.58 2.45 3.38 41.28
85 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 40.72
86 INT170511 Regulation of Localization of Car2 11 0.21 2.18 1.09 40.56
87 INT315006 Regulation of Localization of Tmie 2 0.04 0.26 0.37 40.56
88 INT315586 Gene_expression of SLC25A38 1 0.52 0.51 0 39.88
89 INT315560 Gene_expression of SLC19A2 1 0.55 1.32 0 39.48
90 INT315603 Positive_regulation of Gene_expression of SLC19A2 1 0.41 0.48 0 39.48
91 INT3323 Gene_expression of ALAS2 10 0.58 7.51 0.21 38.48
92 INT3322 Positive_regulation of Gene_expression of ALAS2 4 0.43 3.25 0 38.48
93 INT205596 Negative_regulation of COQ10A 22 0.51 15.61 2.77 36.96
94 INT116831 Binding of Ryr1 11 0.47 0.12 0.9 34.08
95 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 24.80
96 INT20230 Negative_regulation of Positive_regulation of Alb 15 0.56 12.44 4.11 24.80
97 INT57089 Negative_regulation of Cel 10 0.02 4.46 1.58 24.12
98 INT262293 Gene_expression of CC2D1A 21 0.40 44.64 1.5 23.28
99 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 18.32
100 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 17.20
101 INT315621 Gene_expression of CIAO1 1 0.34 4.11 0 16.08
102 INT315622 Protein_catabolism of FECH 1 0.77 0.49 0.07 15.52
103 INT312970 Negative_regulation of ACSL1 1 0.01 0.56 0 13.56
104 INT199644 Positive_regulation of Gene_expression of H2-Q10 3 0.37 2.6 0.15 13.16
105 INT94563 Gene_expression of H2-Q10 7 0.42 7 0.88 12.80
106 INT82177 Negative_regulation of H2-Q10 5 0.58 5.83 0.45 12.80
107 INT60122 Negative_regulation of MADD 3 0.11 2.23 0.93 12.64
108 INT80486 Gene_expression of FECH 13 0.54 10.42 4.8 12.08
109 INT5261 Localization of AGL 10 0.36 3.17 0.61 6.40
110 INT295510 Negative_regulation of Sptlc1 4 0.11 2.11 0 6.32
111 INT312967 Positive_regulation of Binding of AGL 1 0.03 0.55 0 5.80
112 INT76902 Binding of AGL 3 0.02 2.23 0.64 5.56
113 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
114 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
115 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
116 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
117 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
118 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
119 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
120 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
121 INT111051 Negative_regulation of Nav1 64 0.59 25.51 47.27 5.00
122 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 5.00
123 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
124 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
125 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 5.00
126 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 5.00
127 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64 5.00
128 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67 5.00
129 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 5.00
130 INT47741 Negative_regulation of Flvcr2 43 0.51 5.72 23.37 5.00
131 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
132 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
133 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01 5.00
134 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 5.00
135 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 5.00
136 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 5.00
137 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
138 INT73641 Regulation of Lep 45 0.62 26.2 12.59 5.00
139 INT15805 Gene_expression of TFRC 35 0.75 17.44 8.52 5.00
140 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51 5.00
141 INT170504 Positive_regulation of Gene_expression of Car2 60 0.41 19.1 8.45 5.00
142 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91 5.00
143 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27 5.00
144 INT134864 Binding of Calm3 20 0.27 1.86 6.86 5.00
145 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14 5.00
146 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 5.00
147 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 5.00
148 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36 5.00
149 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 5.00
150 INT59555 Binding of RYR1 39 0.42 8.65 4.92 5.00
151 INT22557 Gene_expression of BMP1 3 0.59 20.18 4.73 5.00
152 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 5.00
153 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36 5.00
154 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 5.00
155 INT177992 Positive_regulation of SNRNP70 28 0.49 16.14 4.28 5.00
156 INT50595 Positive_regulation of HRASLS 16 0.49 9.65 4.24 5.00
157 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 5.00
158 INT14091 Binding of Vsig2 8 0.42 3.21 3.91 5.00
159 INT105975 Gene_expression of ACACA 16 0.75 5.73 3.86 5.00
160 INT2936 Gene_expression of AGL 36 0.49 9.55 3.63 5.00
161 INT1727 Gene_expression of Cndp2 22 0.74 4.28 3.34 5.00
162 INT15801 Positive_regulation of TFRC 11 0.33 6.35 3.3 5.00
163 INT307634 Binding of BMP1 1 0.36 3.12 3.26 5.00
164 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
165 INT57767 Gene_expression of HK1 17 0.30 9.72 3.22 5.00
166 INT9549 Regulation of CHKB 25 0.47 13.61 3.2 5.00
167 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 5.00
168 INT32852 Negative_regulation of FECH 18 0.57 10.59 3.08 5.00
169 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07 5.00
170 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05 5.00
171 INT92632 Gene_expression of Vsig2 48 0.50 19.93 3.04 5.00
172 INT146758 Gene_expression of LCN2 45 0.78 38.29 2.97 5.00
173 INT30171 Gene_expression of Calm3 13 0.73 0.58 2.96 5.00
174 INT21853 Regulation of Ap3d1 3 0.10 1.4 2.95 5.00
175 INT24712 Positive_regulation of Ap3d1 18 0.54 8.58 2.71 5.00
176 INT115300 Negative_regulation of Napa 7 0.23 1 2.68 5.00
177 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59 5.00
178 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
179 INT243496 Positive_regulation of Gene_expression of FECH 4 0.40 4.02 2.34 5.00
180 INT133567 Regulation of IL18 11 0.50 9.54 2.31 5.00
181 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 5.00
182 INT282596 Localization of BMP1 2 0.61 4.04 1.97 5.00
183 INT138844 Positive_regulation of CC2D1A 25 0.41 41.36 1.92 5.00
184 INT53567 Positive_regulation of FECH 14 0.45 11.03 1.82 5.00
185 INT70322 Gene_expression of MAPKAP1 10 0.65 6.06 1.7 5.00
186 INT11713 Localization of RYR1 22 0.76 10.42 1.64 5.00
187 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61 5.00
188 INT12890 Gene_expression of Ttr 15 0.63 7.68 1.6 5.00
189 INT101431 Negative_regulation of Gene_expression of Atp9a 12 0.06 4.64 1.57 5.00
190 INT21852 Regulation of Gene_expression of Ap3d1 2 0.18 1.34 1.54 5.00
191 INT182514 Binding of AGTR1 18 0.47 13.35 1.48 5.00
192 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47 5.00
193 INT15798 Positive_regulation of Gene_expression of TFRC 9 0.46 4.99 1.42 5.00
194 INT55305 Regulation of RYR1 14 0.45 5.27 1.33 5.00
195 INT36500 Negative_regulation of Gene_expression of Tf 4 0.38 1.22 1.29 5.00
196 INT162467 Gene_expression of ERN1 10 0.56 5.11 1.26 5.00
197 INT33520 Negative_regulation of CYC1 11 0.57 5.36 1.26 5.00
198 INT302084 Negative_regulation of WNT2 2 0.09 0.83 1.26 5.00
199 INT115264 Binding of FECH 9 0.41 7.93 1.1 5.00
200 INT162471 Positive_regulation of ERN1 7 0.34 3.02 1.08 5.00
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