D:Myotonia

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pChart

Disease Term
Synonyms Myotonia Percussion, Myotonias, Myotonias Percussion, Myotonic Phenomenon, Myotonic Phenomenons, PERCUSSION MYOTONIA, Percussion Myotonias, Phenomenon Myotonic, Phenomenons Myotonic
Documents 20
Hot Single Events 20
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Myotonia. They are ordered first by their relevance to Myotonia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT150446 Binding of Clcn1 and Scn4a 1 0.26 0.65 0.08 92.08
2 INT311390 Mbnl1 Positive_regulation of Celf1 1 0.26 0.48 0 79.32
3 INT311387 Binding of Celf1 and Mbnl1 1 0.20 0.25 0 9.00
4 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12 5.00
5 INT272517 Binding of Ccnd1 and Celf1 3 0.08 0.07 0 5.00
6 INT311405 CCND3 Regulation of Celf1 1 0.41 0.14 0 5.00
7 INT311404 Binding of CDKN2A and Celf1 1 0.32 0.07 0 5.00
8 INT311389 Positive_regulation of Binding of Celf1 and Eif2s2 1 0.17 0.59 0 5.00
9 INT311381 Phosphorylation of Akt1 Regulation of Celf1 1 0.10 0.14 0 5.00
10 INT311379 Celf1 Negative_regulation of Mbnl1 1 0.24 0.26 0 5.00
11 INT311384 Binding of Cnbp and Eef2 1 0.07 0.15 0 5.00
12 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0 5.00
13 INT311385 Gopc Regulation of Celf1 1 0.04 0.14 0 5.00
14 INT272516 Binding of Celf1 and Tpt1 2 0.05 0.07 0 5.00
15 INT311380 Positive_regulation of Celf1 Negative_regulation of Mbnl1 1 0.26 0.26 0 5.00
16 INT311393 Binding of Eef2 and Rps17 1 0.02 0.15 0 5.00
17 INT311392 Binding of Cnbp and Pabpc1 1 0.04 0.14 0 5.00
18 INT311397 Binding of Celf1 and Gopc 1 0.04 0.09 0 5.00
19 INT311378 Binding of Cnbp and Rps17 1 0.06 0.14 0 5.00
20 INT311375 Phosphorylation of Prkca Positive_regulation of Celf1 1 0.04 0.1 0 5.00
21 INT311402 Binding of Celf1 and Eif2s2 Positive_regulation of Phosphorylation of Celf1 1 0.11 0.22 0 5.00
22 INT311394 Binding of Celf1 and Eif2s2 1 0.12 1.67 0 5.00
23 INT311391 Binding of Celf1 and Dmpk 1 0.34 0.09 0 5.00
24 INT311395 Binding of Esr1 and 20S 1 0.04 0.11 0 5.00
25 INT311383 Mbnl1 Regulation of Insr 1 0.00 0.24 0 5.00
26 INT311376 Binding of Ccnd3 and Celf1 1 0.06 0.07 0 5.00
27 INT311386 Celf1 Regulation of Insr 1 0.00 0.24 0 5.00
28 INT311388 Mbnl1 Positive_regulation of Binding of Celf1 1 0.26 0.13 0 5.00
29 INT311377 Binding of Eef2 and Pabpc1 1 0.01 0.15 0 5.00
30 INT311396 Akt1 Regulation of Celf1 1 0.04 0.14 0 5.00
31 INT311403 CDKN2A Regulation of Celf1 1 0.41 0.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Myotonia. They are ordered first by their pain relevance and then by number of times they were reported in Myotonia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT311337 Positive_regulation of Uts2r 3 0.12 1.34 0.05 98.12
2 INT72591 Gene_expression of Scn4a 2 0.64 0.65 1.05 98.04
3 INT16854 Gene_expression of Uts2r 17 0.26 3.1 1.31 97.20
4 INT211584 Gene_expression of Dmpk 32 0.73 12.28 0.46 96.92
5 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47 96.04
6 INT19466 Negative_regulation of Clcn1 6 0.52 3.39 1.22 95.76
7 INT21502 Gene_expression of Scn4a 22 0.78 4.47 7.97 95.76
8 INT16178 Gene_expression of Clcn1 20 0.69 8.67 1.46 93.88
9 INT255100 Positive_regulation of Gene_expression of Dmpk 8 0.56 3.3 0.13 92.96
10 INT274423 Positive_regulation of Gene_expression of Uts2r 3 0.09 0.58 0 92.96
11 INT251238 Gene_expression of Lvs 35 0.32 29.41 1.59 92.88
12 INT255112 Negative_regulation of Mbnl1 22 0.58 8.5 0.45 92.16
13 INT311345 Protein_catabolism of Efemp2 1 0.01 1.03 0 88.56
14 INT311309 Protein_catabolism of Dmpk 1 0.67 0.62 0 88.56
15 INT255128 Binding of Mbnl1 13 0.37 4.34 0.09 87.04
16 INT255101 Positive_regulation of Celf1 23 0.56 11.91 0.84 86.40
17 INT255135 Positive_regulation of Gene_expression of Celf1 18 0.56 5.84 0.43 86.40
18 INT255120 Gene_expression of Celf1 29 0.62 10.82 0.59 86.00
19 INT255131 Gene_expression of Mbnl1 34 0.77 10.44 0.55 83.56
20 INT97777 Positive_regulation of CNBP 7 0.37 9.85 1.09 82.80
21 INT311330 Negative_regulation of Positive_regulation of Celf1 1 0.35 0.85 0 79.84
22 INT255097 Positive_regulation of Dmpk 4 0.61 2.06 0 78.24
23 INT255116 Positive_regulation of Positive_regulation of Dmpk 2 0.44 1.01 0 78.24
24 INT19044 Positive_regulation of GGT5 10 0.65 7.7 1.11 73.28
25 INT311334 Positive_regulation of Localization of Dmpk 1 0.38 0.76 0 72.88
26 INT38283 Positive_regulation of Cebpg 2 0.04 1.96 0.69 72.76
27 INT255129 Localization of Dmpk 5 0.65 3.1 0.07 71.28
28 INT255113 Positive_regulation of Gene_expression of Mbnl1 15 0.69 3.28 0.47 68.12
29 INT311316 Protein_catabolism of Cnbp 1 0.59 0.48 0 59.36
30 INT311325 Negative_regulation of Binding of Cnbp 1 0.39 0.16 0 11.44
31 INT311343 Negative_regulation of Cnbp 1 0.28 0.16 0 11.44
32 INT311308 Binding of Cnbp 1 0.32 0.27 0 6.72
33 INT272471 Binding of Celf1 5 0.39 4.97 0.56 5.16
34 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 5.00
35 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
36 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04 5.00
37 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47 5.00
38 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89 5.00
39 INT75136 Binding of Akt1 27 0.27 8.81 4.15 5.00
40 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91 5.00
41 INT109007 Positive_regulation of Ccnd1 23 0.53 9.5 0.86 5.00
42 INT272475 Regulation of Mbnl1 15 0.61 5.39 0.56 5.00
43 INT277278 Regulation of Celf1 4 0.49 4.63 0.48 5.00
44 INT199457 Binding of Gstp1 3 0.23 1.68 0.44 5.00
45 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32 5.00
46 INT124851 Negative_regulation of Tpt1 13 0.43 2.92 0.32 5.00
47 INT255132 Positive_regulation of Mbnl1 15 0.54 2.58 0.27 5.00
48 INT26678 Negative_regulation of Dmpk 11 0.47 3.45 0.26 5.00
49 INT100459 Binding of Xrcc1 5 0.46 4.41 0.25 5.00
50 INT277269 Positive_regulation of Binding of Celf1 2 0.40 0.89 0.24 5.00
51 INT271731 Binding of 20S 4 0.47 2.12 0.18 5.00
52 INT255125 Localization of Celf1 7 0.60 2.84 0.11 5.00
53 INT255110 Binding of Dmpk 9 0.39 1.41 0.11 5.00
54 INT234193 Binding of Tpt1 5 0.31 1.5 0.09 5.00
55 INT272486 Phosphorylation of Celf1 10 0.66 4.63 0.08 5.00
56 INT255119 Positive_regulation of Positive_regulation of Celf1 3 0.40 1.26 0.05 5.00
57 INT272467 Positive_regulation of Phosphorylation of Celf1 3 0.56 1.61 0.05 5.00
58 INT255136 Regulation of Gene_expression of Dmpk 2 0.39 0.56 0.05 5.00
59 INT311331 Negative_regulation of Binding of Celf1 1 0.34 0 0.04 5.00
60 INT311304 Phosphorylation of Eif2s2 1 0.22 0.06 0.03 5.00
61 INT272485 Regulation of Transcription of Dmpk 4 0.50 0.56 0.03 5.00
62 INT155564 Negative_regulation of Efemp2 4 0.43 0.53 0.03 5.00
63 INT311305 Positive_regulation of Eif2s2 1 0.19 0.57 0.03 5.00
64 INT211585 Negative_regulation of Gene_expression of Dmpk 5 0.47 1.63 0.03 5.00
65 INT255102 Transcription of Dmpk 8 0.60 2.47 0.03 5.00
66 INT311300 Gene_expression of Cnbp 1 0.45 0 0 5.00
67 INT311364 Binding of CCND3 1 0.36 0.47 0 5.00
68 INT311306 Regulation of Transcription of Celf1 1 0.22 0.29 0 5.00
69 INT272479 Regulation of Dmpk 2 0.50 0.45 0 5.00
70 INT196430 Gene_expression of Ccnd3 5 0.14 1.92 0 5.00
71 INT311310 Regulation of Binding of Celf1 1 0.36 0.88 0 5.00
72 INT311340 Positive_regulation of Transcription of Celf1 1 0.40 0.08 0 5.00
73 INT311317 Positive_regulation of Negative_regulation of Efemp2 1 0.01 0 0 5.00
74 INT272478 Regulation of Phosphorylation of Celf1 2 0.49 0.36 0 5.00
75 INT255108 Regulation of Gene_expression of Celf1 2 0.36 0.18 0 5.00
76 INT311342 Positive_regulation of Negative_regulation of Mbnl1 1 0.30 0.26 0 5.00
77 INT272459 Negative_regulation of Phosphorylation of Celf1 2 0.47 0.55 0 5.00
78 INT311341 Regulation of Binding of Eif2s2 1 0.11 0.39 0 5.00
79 INT306876 Phosphorylation of CCND3 2 0.35 0.21 0 5.00
80 INT296685 Negative_regulation of 20S 3 0.57 0.18 0 5.00
81 INT311302 Positive_regulation of Protein_catabolism of Celf1 1 0.40 0.13 0 5.00
82 INT311322 Transcription of Celf1 1 0.55 0.38 0 5.00
83 INT311313 Negative_regulation of Transcription of Dmpk 1 0.38 0 0 5.00
84 INT272472 Phosphorylation of Dmpk 2 0.72 1.05 0 5.00
85 INT311327 Protein_catabolism of Celf1 1 0.71 0.13 0 5.00
86 INT311320 Regulation of Cnbp 1 0.30 0 0 5.00
87 INT311335 Negative_regulation of Localization of Dmpk 1 0.33 0 0 5.00
88 INT311303 Regulation of Protein_catabolism of Dmpk 1 0.21 0.07 0 5.00
89 INT311326 Positive_regulation of Gene_expression of Ccnd3 1 0.09 0.43 0 5.00
90 INT311329 Positive_regulation of Hdac1 1 0.19 0.14 0 5.00
91 INT311319 Positive_regulation of Binding of Eif2s2 1 0.14 0.51 0 5.00
92 INT272470 Binding of Eif2s2 2 0.10 0.95 0 5.00
93 INT311315 Regulation of Positive_regulation of Celf1 1 0.22 0.29 0 5.00
94 INT311323 Binding of Ccnd3 1 0.07 0.07 0 5.00
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