D:Nasal Tumor

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Disease Term
Synonyms Angiofibroma, Angiofibromas, NASAL TUMORS, Nasal Tumour, NASAL TUMOURS, Nasopharyngeal Tumor, Nasopharyngeal Tumors, Nasopharyngeal Tumour, NASOPHARYNGEAL TUMOURS
Documents 88
Hot Single Events 22
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nasal Tumor. They are ordered first by their relevance to Nasal Tumor and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 86.64
2 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 86.64
3 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08 61.00
4 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0 45.60
5 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0 34.64
6 INT197811 Binding of SMS and SST 1 0.00 0.98 0.21 5.00
7 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1 5.00
8 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07 5.00
9 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03 5.00
10 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0 5.00
11 INT197809 Binding of MEN1 and VIM 1 0.04 0.52 0 5.00
12 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0 5.00
13 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0 5.00
14 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0 5.00
15 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0 5.00
16 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0 5.00
17 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0 5.00
18 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0 5.00
19 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0 5.00
20 INT197812 Binding of AMBP and RDBP 1 0.00 0.51 0 5.00
21 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0 5.00
22 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0 5.00
23 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0 5.00
24 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0 5.00
25 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0 5.00
26 INT271982 Binding of Skp2 and Psmd9 1 0.01 0.68 0 5.00
27 INT272013 Binding of OGG1 and Tsc2 1 0.09 0.67 0 5.00
28 INT272010 Tsc2 Negative_regulation of OGG1 1 0.17 0.6 0 5.00
29 INT271966 Phosphorylation of Rasa1 Positive_regulation of Tsc2 1 0.01 0.31 0 5.00
30 INT197817 Binding of JUND and MEN1 1 0.18 0.14 0 5.00
31 INT272000 Binding of Skp2 and Hecw1 1 0.01 0.11 0 5.00
32 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0 5.00
33 INT271979 Skp2 Positive_regulation of Protein_catabolism of Psmd9 1 0.01 0.35 0 5.00
34 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0 5.00
35 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0 5.00
36 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0 5.00
37 INT272016 Mtor Negative_regulation of INS 1 0.00 0.61 0 5.00
38 INT271997 Binding of Cdk1 and Plk1 1 0.03 0.3 0 5.00
39 INT271984 Binding of Tsc2 and Skp2 1 0.06 0.34 0 5.00
40 INT272011 Binding of RAB5A and Tsc2 1 0.02 0.16 0 5.00
41 INT272004 Binding of Hspa1b and Tsc2 1 0.01 0.45 0 5.00
42 INT271983 Binding of Tsc2 and Rap1a 1 0.02 0.16 0 5.00
43 INT197815 Binding of MEN1 and TGFB1 1 0.16 0.13 0 5.00
44 INT272005 Phosphorylation of Tsc1 Regulation of Binding of Cdk1 and Plk1 1 0.02 0.3 0 5.00
45 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0 5.00
46 INT271989 Binding of Tsc2 and Psmd9 1 0.02 0.47 0 5.00
47 INT272007 Binding of Tsc2 and SCPEP1 1 0.27 0.46 0 5.00
48 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0 5.00
49 INT271978 Positive_regulation of Racgap1 Regulation of Mtor 1 0.00 0.54 0 5.00
50 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0 5.00
51 INT271987 Tsc2 Regulation of Skp2 1 0.10 0.28 0 5.00
52 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nasal Tumor. They are ordered first by their pain relevance and then by number of times they were reported in Nasal Tumor. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT184803 Localization of TSC1 5 0.37 6.13 0.32 100.00
2 INT68565 Gene_expression of Fap 14 0.57 24.39 1.14 99.14
3 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 99.00
4 INT197832 Localization of MEN1 1 0.80 11.01 0.63 98.68
5 INT246502 Negative_regulation of Men1 2 0.30 8.9 0.33 97.84
6 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26 97.66
7 INT97779 Negative_regulation of TSC2 3 0.41 3.45 0.26 97.48
8 INT95636 Gene_expression of ACTG2 23 0.44 19.87 1.75 96.96
9 INT79425 Gene_expression of SMN1 42 0.65 36.37 6.1 96.54
10 INT246036 Positive_regulation of GRN 3 0.17 2.04 0.69 92.24
11 INT197828 Negative_regulation of MEN1 1 0.43 5.06 0.06 92.08
12 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03 90.60
13 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 89.60
14 INT214073 Binding of TSC1 9 0.37 22 1.34 89.24
15 INT15752 Positive_regulation of Ema 15 0.40 14.57 2.34 89.04
16 INT197841 Positive_regulation of MEN1 1 0.41 2.38 0 88.92
17 INT626 Localization of CALCA 289 0.81 125.39 221.15 88.48
18 INT300623 Positive_regulation of Men1 1 0.35 10.65 0.57 88.08
19 INT443 Localization of POMC 1020 0.81 284.52 443.17 87.52
20 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 80.24
21 INT27935 Binding of Vim 21 0.36 15.65 2.61 80.08
22 INT88070 Binding of Ema 7 0.18 7.39 0.31 80.08
23 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04 77.76
24 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04 76.96
25 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 75.00
26 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78 72.96
27 INT93885 Positive_regulation of Gene_expression of MKI67 8 0.60 4.4 0.18 70.56
28 INT157135 Positive_regulation of MKI67 10 0.60 7.51 0.28 69.84
29 INT99176 Positive_regulation of Fap 4 0.13 7.5 0.22 51.04
30 INT73627 Binding of Fap 8 0.36 11.14 0.4 47.48
31 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28 43.04
32 INT197839 Negative_regulation of PHPT1 1 0.04 2.88 0.06 42.72
33 INT197842 Gene_expression of PHPT1 1 0.06 5.89 0.16 40.12
34 INT197835 Positive_regulation of Gene_expression of PHPT1 1 0.04 3.17 0.07 40.12
35 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43 39.80
36 INT197836 Positive_regulation of Gene_expression of MEN1 1 0.50 3.16 0.07 39.80
37 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 37.80
38 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 37.80
39 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 33.16
40 INT196324 Localization of Cyp2b10 5 0.73 2.81 0.13 23.12
41 INT242822 Transcription of Fap 1 0.18 1.2 0 20.48
42 INT142117 Regulation of Runx2 6 0.61 2.75 0.22 16.00
43 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16 8.36
44 INT286095 Gene_expression of Afap1 1 0.09 2.42 0.03 5.76
45 INT158 Localization of Prl 2431 0.81 378.96 952.2 5.00
46 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 5.00
47 INT1893 Localization of Gh 1041 0.79 340.23 256.58 5.00
48 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 5.00
49 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 5.00
50 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 5.00
51 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
52 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
53 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
54 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
55 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
56 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
57 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
58 INT397 Localization of SST 232 0.81 58.05 101.19 5.00
59 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 5.00
60 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
61 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 5.00
62 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 5.00
63 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 5.00
64 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
65 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
66 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
67 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
68 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
69 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 5.00
70 INT1578 Negative_regulation of Localization of PRL 52 0.59 20.62 17.18 5.00
71 INT2243 Localization of GAST 67 0.81 34.54 16.19 5.00
72 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 5.00
73 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
74 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
75 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02 5.00
76 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
77 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 5.00
78 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 5.00
79 INT200874 Positive_regulation of Localization of Gopc 27 0.38 5.69 7.5 5.00
80 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 5.00
81 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
82 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 5.00
83 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 5.00
84 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79 5.00
85 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 5.00
86 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 5.00
87 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66 5.00
88 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55 5.00
89 INT165841 Gene_expression of BPIFA4P 17 0.65 6.48 2.38 5.00
90 INT9473 Binding of MUC1 66 0.48 46.77 2.36 5.00
91 INT55470 Regulation of Mtor 16 0.24 12.51 2.07 5.00
92 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77 5.00
93 INT3818 Regulation of Apc 13 0.39 12.52 1.68 5.00
94 INT106359 Regulation of Plau 7 0.45 3.51 1.5 5.00
95 INT18156 Gene_expression of Fap 18 0.73 27.02 1.46 5.00
96 INT46736 Negative_regulation of Odc1 10 0.51 7.6 1.39 5.00
97 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 5.00
98 INT220177 Binding of Apc 21 0.37 15.34 1.37 5.00
99 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 5.00
100 INT152951 Negative_regulation of LEF1 5 0.41 3.22 1.31 5.00
101 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3 5.00
102 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16 5.00
103 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01 5.00
104 INT27387 Binding of Aecp 4 0.34 5.09 1 5.00
105 INT23660 Negative_regulation of Fap 5 0.35 8.93 0.95 5.00
106 INT43484 Binding of Runx2 7 0.37 3.22 0.95 5.00
107 INT126523 Phosphorylation of Mapkapk2 19 0.79 7.76 0.82 5.00
108 INT74019 Regulation of TSC1 27 0.35 23.61 0.79 5.00
109 INT131384 Binding of Mutyh 5 0.26 2.41 0.78 5.00
110 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74 5.00
111 INT2244 Positive_regulation of Localization of GAST 7 0.68 5.28 0.73 5.00
112 INT184694 Gene_expression of Usf1 10 0.55 4.27 0.72 5.00
113 INT68564 Binding of Fap 6 0.32 6.75 0.65 5.00
114 INT142123 Positive_regulation of Gene_expression of Runx2 17 0.64 4.81 0.65 5.00
115 INT115423 Gene_expression of Men1 4 0.47 14.08 0.64 5.00
116 INT71497 Binding of Hspa1b 3 0.08 1.43 0.58 5.00
117 INT182435 Localization of OGG1 36 0.76 1.66 0.58 5.00
118 INT91209 Binding of VIM 15 0.36 12.02 0.53 5.00
119 INT300621 Localization of Men1 1 0.56 4.63 0.52 5.00
120 INT183629 Gene_expression of Ctnnd2 14 0.75 11.78 0.48 5.00
121 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47 5.00
122 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46 5.00
123 INT214067 Regulation of Scrib 11 0.20 12.48 0.45 5.00
124 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 5.00
125 INT58679 Gene_expression of Odc1 13 0.78 9.55 0.45 5.00
126 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44 5.00
127 INT247798 Negative_regulation of Rasa1 3 0.09 1.05 0.44 5.00
128 INT230653 Phosphorylation of Rasa1 3 0.55 0.6 0.42 5.00
129 INT271922 Phosphorylation of Cdk1 2 0.44 0.37 0.39 5.00
130 INT225667 Transcription of Apc 3 0.52 3.73 0.32 5.00
131 INT182073 Binding of APEX1 4 0.12 1.72 0.32 5.00
132 INT126522 Positive_regulation of Phosphorylation of Mapkapk2 7 0.59 3.8 0.28 5.00
133 INT70144 Gene_expression of Sry 4 0.63 1.15 0.28 5.00
134 INT241240 Gene_expression of Pkd1 18 0.54 12.2 0.27 5.00
135 INT246762 Phosphorylation of Tsc2 60 0.67 15.71 0.25 5.00
136 INT171716 Regulation of Fap 4 0.27 4.05 0.23 5.00
137 INT182413 Binding of OGG1 17 0.46 2.44 0.22 5.00
138 INT271929 Protein_catabolism of Psmd9 4 0.11 1.69 0.21 5.00
139 INT260174 Gene_expression of Rpe65 29 0.78 4.2 0.19 5.00
140 INT171614 Positive_regulation of Runx2 13 0.63 3.04 0.19 5.00
141 INT286108 Negative_regulation of Afap1 1 0.08 3.35 0.18 5.00
142 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18 5.00
143 INT271943 Phosphorylation of Tsc2 9 0.52 3.35 0.13 5.00
144 INT271573 Binding of SCPEP1 3 0.35 1.21 0.13 5.00
145 INT246749 Negative_regulation of Phosphorylation of Tsc2 11 0.35 3.4 0.12 5.00
146 INT246776 Negative_regulation of Tsc2 18 0.48 6.82 0.12 5.00
147 INT208551 Gene_expression of Mutyh 6 0.48 6.28 0.12 5.00
148 INT271941 Binding of Tsc2 12 0.24 2.96 0.11 5.00
149 INT197840 Binding of NME1 2 0.04 1.14 0.11 5.00
150 INT242819 Negative_regulation of Gene_expression of Apc 4 0.37 5.6 0.1 5.00
151 INT211942 Transcription of Runx2 3 0.69 2.46 0.08 5.00
152 INT140494 Negative_regulation of Fap 3 0.37 2.3 0.08 5.00
153 INT197827 Regulation of PHPT1 1 0.03 2.54 0.08 5.00
154 INT38741 Binding of ring-3H 1 0.30 0 0.07 5.00
155 INT271938 Binding of Tsc1 1 0.43 3.18 0.07 5.00
156 INT58681 Positive_regulation of Gene_expression of Odc1 2 0.70 1.13 0.07 5.00
157 INT211006 Binding of PKD1 6 0.22 2.69 0.05 5.00
158 INT197280 Regulation of Psmd9 2 0.07 0.1 0.05 5.00
159 INT271916 Positive_regulation of Phosphorylation of Tsc2 4 0.32 0.52 0.04 5.00
160 INT286105 Positive_regulation of Mutyh 1 0.36 1.94 0.04 5.00
161 INT271937 Positive_regulation of Binding of Tsc2 1 0.25 0 0.04 5.00
162 INT286102 Positive_regulation of Fap 5 0.30 8.58 0.04 5.00
163 INT119227 Gene_expression of Tsc2 8 0.68 10.67 0.03 5.00
164 INT249790 Protein_catabolism of Skp2 2 0.58 1.02 0.03 5.00
165 INT271964 Binding of HERC1 1 0.01 0.31 0 5.00
166 INT271935 Positive_regulation of Phosphorylation of Rps6 1 0.02 0.17 0 5.00
167 INT271924 Positive_regulation of Protein_catabolism of Psmd9 1 0.05 0.35 0 5.00
168 INT242821 Negative_regulation of Localization of Fap 1 0.11 1.91 0 5.00
169 INT286106 Positive_regulation of Gene_expression of Mutyh 1 0.36 0.66 0 5.00
170 INT271905 Positive_regulation of Protein_catabolism of Tsc2 1 0.35 1.46 0 5.00
171 INT271965 Negative_regulation of Binding of TSC1 1 0.33 0.44 0 5.00
172 INT271921 Negative_regulation of Tsc2 2 0.26 1.19 0 5.00
173 INT271928 Binding of Plk1 1 0.07 0.29 0 5.00
174 INT286101 Protein_catabolism of Ctnnd2 1 0.64 1.14 0 5.00
175 INT271904 Localization of Tsc2 1 0.41 1.31 0 5.00
176 INT286097 Binding of Afap1 1 0.05 1.72 0 5.00
177 INT246774 Positive_regulation of Tsc2 6 0.41 2.4 0 5.00
178 INT265588 Localization of Fap 4 0.47 5.67 0 5.00
179 INT228895 Binding of Tsc2 5 0.30 2.41 0 5.00
180 INT242820 Localization of Fap 1 0.20 1.9 0 5.00
181 INT271936 Phosphorylation of Tsc1 4 0.73 1.76 0 5.00
182 INT246755 Regulation of Tsc2 4 0.50 1.01 0 5.00
183 INT197843 Regulation of Localization of MEN1 1 0.45 0.24 0 5.00
184 INT197838 Transcription of MEN1 1 0.69 0.13 0 5.00
185 INT161700 Positive_regulation of Psmd9 3 0.59 0.41 0 5.00
186 INT286104 Negative_regulation of Mutyh 1 0.35 2.24 0 5.00
187 INT271919 Gene_expression of Tsc2 6 0.39 2.23 0 5.00
188 INT271962 Localization of SLC7A6 1 0.73 0.08 0 5.00
189 INT197825 Transcription of JUND 2 0.29 0.43 0 5.00
190 INT286107 Positive_regulation of Phosphorylation of Fap 1 0.30 3.5 0 5.00
191 INT242456 Binding of Cdk2 2 0.16 1.29 0 5.00
192 INT271913 Protein_catabolism of Tsc1 1 0.51 0.45 0 5.00
193 INT271940 Protein_catabolism of Tsc2 1 0.50 0.7 0 5.00
194 INT286100 Binding of Rpa3 1 0.36 0 0 5.00
195 INT197829 Positive_regulation of Transcription of JUND 2 0.21 0.82 0 5.00
196 INT286103 Regulation of Gene_expression of Fap 1 0.16 1.49 0 5.00
197 INT271906 Negative_regulation of Binding of Tsc1 1 0.38 0.06 0 5.00
198 INT182417 Positive_regulation of OGG1 2 0.44 0.83 0 5.00
199 INT214045 Negative_regulation of OGG1 5 0.36 3.49 0 5.00
200 INT265823 Binding of WHSC1 1 0.08 1.17 0 5.00
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