D:Necrolytic Migratory Erythema

Disease Term Synonyms Erythema Necrolytic Migratory, Erythemas Necrolytic Migratory, Migratory Erythema Necrolytic, Migratory Erythemas Necrolytic, NECROLYTIC MIGRATORY ERYTHEMAS, Pseudoglucagonoma Syndrome, PSEUDOGLUCAGONOMA SYNDROMES, SYNDROME PSEUDOGLUCAGONOMA, Syndromes Pseudoglucagonoma Documents 8 Hot Single Events 6 Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Necrolytic Migratory Erythema. They are ordered first by their relevance to Necrolytic Migratory Erythema and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT303655	Positive_regulation of Binding of IGF1 and SSTR1	1	0.16	2.19	0.41	13.92
2	INT303650	Binding of IGF1 and SSTR1	1	0.12	2.17	0.4	12.48
3	INT30905	SST Negative_regulation of Localization of GCG	2	0.12	1.56	1.04	5.00
4	INT75283	SST Negative_regulation of Localization of INS	2	0.47	1.45	0.96	5.00
5	INT303656	SST Negative_regulation of Localization of GAST	1	0.12	1.45	0.82	5.00
6	INT303652	Binding of SST and SSTR2	1	0.26	0.46	0.57	5.00
7	INT303654	Binding of SST and SSTR5	1	0.22	0.46	0.57	5.00
8	INT303653	Binding of DRD2 and SST	1	0.18	0.45	0.54	5.00
9	INT303651	Binding of SSTR2 and SSTR5	1	0.24	0.23	0.45	5.00
10	INT303657	Gene_expression of SSTR2 Negative_regulation of Gene_expression of SST	1	0.30	0.94	0.16	5.00
11	INT303659	SSTR2 Negative_regulation of Gene_expression of SST	1	0.30	0.94	0.16	5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Necrolytic Migratory Erythema. They are ordered first by their pain relevance and then by number of times they were reported in Necrolytic Migratory Erythema. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT397	Localization of SST	232	0.81	58.05	101.19	97.44
2	INT7412	Positive_regulation of SST	71	0.70	24.44	29.48	89.24
3	INT30629	Regulation of Positive_regulation of SST	2	0.37	1.35	0.59	85.04
4	INT692	Negative_regulation of SST	72	0.59	28.68	34.52	84.52
5	INT67195	Negative_regulation of Gene_expression of SST	7	0.42	6.98	4.88	84.52
6	INT8347	Gene_expression of SST	181	0.78	104.59	65.45	83.88
7	INT243480	Gene_expression of SSTR5	1	0.55	4.25	0.85	76.48
8	INT303676	Regulation of Gene_expression of SSTR5	1	0.32	1.69	0.28	76.48
9	INT3395	Negative_regulation of VIP	15	0.59	4.23	5.62	73.64
10	INT303680	Negative_regulation of Positive_regulation of VIP	1	0.15	1.2	0.28	73.64
11	INT7336	Positive_regulation of VIP	60	0.70	24.2	19.62	72.88
12	INT14930	Regulation of Gene_expression of SST	12	0.45	6.86	3.89	68.88
13	INT4494	Regulation of GCG	41	0.45	18.38	9.68	38.08
14	INT303671	Negative_regulation of Regulation of GCG	1	0.13	1.44	0.22	38.08
15	INT14681	Negative_regulation of GCG	31	0.57	13.55	4.98	36.56
16	INT228975	Gene_expression of SERPINA2	1	0.31	1.61	0	32.16
17	INT303672	Negative_regulation of Gene_expression of SSTR2	1	0.49	0.95	0.21	27.16
18	INT140542	Gene_expression of SSTR2	18	0.65	13.58	3.94	26.68
19	INT26492	Negative_regulation of Localization of GCG	73	0.58	22.2	9.48	25.76
20	INT17625	Localization of GCG	210	0.80	55.69	24.97	24.32
21	INT144461	Negative_regulation of SSTR2	2	0.49	1.03	0.98	21.48
22	INT243477	Binding of SSTR1	3	0.26	3.49	0.65	12.48
23	INT3252	Negative_regulation of INS	428	0.59	271.65	39.52	11.00
24	INT28951	Negative_regulation of IGF1	133	0.59	75.77	18.9	11.00
25	INT68684	Gene_expression of VEGFA	2371	0.78	1742.52	259.2	5.00
26	INT867	Gene_expression of IFNA1	930	0.78	594.85	168.03	5.00
27	INT812	Localization of INS	1026	0.81	515.6	145.31	5.00
28	INT546	Binding of ALB	311	0.48	85.98	60.14	5.00
29	INT249	Localization of GHRH	215	0.80	78.02	51.87	5.00
30	INT5118	Regulation of SST	97	0.62	34.35	51.74	5.00
31	INT80124	Negative_regulation of VEGFA	450	0.58	311.19	44.53	5.00
32	INT3758	Gene_expression of ALB	326	0.78	184.65	38.75	5.00
33	INT3253	Negative_regulation of Localization of INS	205	0.59	130.39	36.61	5.00
34	INT691	Binding of SST	67	0.48	24.66	32.67	5.00
35	INT48693	Regulation of VEGFA	268	0.62	191.88	31.52	5.00
36	INT99688	Negative_regulation of Gene_expression of VEGFA	274	0.58	201.8	31.1	5.00
37	INT11159	Gene_expression of EGFR	698	0.78	548.93	25.69	5.00
38	INT693	Negative_regulation of Localization of SST	46	0.59	8.57	21.75	5.00
39	INT28642	Gene_expression of CXCR2	60	0.78	38.69	18.11	5.00
40	INT7414	Regulation of Localization of SST	31	0.60	4.85	17.46	5.00
41	INT2243	Localization of GAST	67	0.81	34.54	16.19	5.00
42	INT63773	Gene_expression of DRD2	25	0.78	10.41	10.8	5.00
43	INT6810	Gene_expression of ENO2	70	0.78	54.8	8.35	5.00
44	INT15529	Gene_expression of GCG	51	0.75	18.55	8.35	5.00
45	INT24724	Positive_regulation of Gene_expression of SST	11	0.67	7.51	6.12	5.00
46	INT11158	Positive_regulation of Gene_expression of EGFR	165	0.70	131.26	4.93	5.00
47	INT138872	Gene_expression of SPINK5	21	0.58	30.11	4.12	5.00
48	INT986	Negative_regulation of Localization of GHRH	16	0.58	8.57	3.16	5.00
49	INT13733	Localization of SSTR1	8	0.65	3.11	2.49	5.00
50	INT49769	Binding of SSTR2	4	0.48	1.39	2.14	5.00
51	INT44783	Gene_expression of Chga	3	0.75	1.72	1.45	5.00
52	INT212466	Regulation of EPHB1	7	0.37	5.72	1.42	5.00
53	INT124407	Gene_expression of SSTR1	4	0.55	5.55	1.41	5.00
54	INT303667	Regulation of BCL2L11	3	0.16	1.03	1.21	5.00
55	INT219879	Positive_regulation of SPINK5	4	0.30	7.64	1.16	5.00
56	INT294726	Positive_regulation of Lts1	5	0.49	4.06	0.87	5.00
57	INT118350	Negative_regulation of Chga	2	0.42	1.64	0.71	5.00
58	INT41555	Gene_expression of GRN	8	0.52	10.94	0.69	5.00
59	INT246036	Positive_regulation of GRN	3	0.17	2.04	0.69	5.00
60	INT202187	Regulation of GRN	3	0.09	1.47	0.53	5.00
61	INT303669	Regulation of SPINK5	1	0.24	0.65	0.53	5.00
62	INT303674	Positive_regulation of Regulation of BCL2L11	1	0.02	0.28	0.5	5.00
63	INT228977	Binding of SERPINA2	1	0.25	5.42	0.35	5.00
64	INT303673	Gene_expression of C10orf81	1	0.01	0.58	0.24	5.00
65	INT158763	Binding of GRN	3	0.36	0.94	0.2	5.00
66	INT274731	Binding of EPHB1	3	0.22	0.76	0.2	5.00
67	INT303678	Regulation of Gene_expression of SSTR1	1	0.19	0.84	0.18	5.00
68	INT228976	Binding of MCAT	3	0.06	3.45	0.17	5.00
69	INT303668	Positive_regulation of Gene_expression of SSTR2	1	0.42	0.66	0.16	5.00
70	INT303677	Positive_regulation of SSTR2	1	0.42	0.56	0.16	5.00
71	INT303649	Gene_expression of Ptprf	1	0.58	0.96	0.11	5.00