D:Necrosis

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Disease Term
Synonyms Necroses
Documents 12460
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Necrosis. They are ordered first by their relevance to Necrosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62 100.00
2 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55 100.00
3 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54 100.00
4 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 100.00
5 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37 100.00
6 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33 100.00
7 INT250553 Binding of RS1 and SUGT1 3 0.00 3.36 0.22 100.00
8 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58 100.00
9 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55 100.00
10 INT61827 Tnf Regulation of Lta 1 0.40 1.5 0.58 100.00
11 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63 100.00
12 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75 100.00
13 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51 100.00
14 INT297689 Atn1 Regulation of Gene_expression of Il6 1 0.02 1.13 0.44 100.00
15 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82 100.00
16 INT297695 Binding of Atn1 and Fut1 1 0.01 0.68 0.12 100.00
17 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82 100.00
18 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8 100.00
19 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89 100.00
20 INT9162 Tnf Negative_regulation of Localization of Penk 1 0.34 0.85 0.3 100.00
21 INT9161 Tnf Negative_regulation of Localization of Ifng 1 0.20 0.85 0.3 100.00
22 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19 100.00
23 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19 100.00
24 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19 100.00
25 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19 100.00
26 INT153750 Binding of CCL2 and Crp 1 0.02 1.8 0.65 100.00
27 INT153751 Regulation of Binding of CCL2 and Crp 1 0.03 1.8 0.65 100.00
28 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71 100.00
29 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 100.00
30 INT86380 Adra2a Regulation of Gene_expression of Tnf 1 0.15 0.79 0.44 100.00
31 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7 100.00
32 INT81731 POMC Regulation of Gene_expression of TNF 1 0.28 1.07 0.39 100.00
33 INT4875 TNF Regulation of MME 1 0.51 0.71 0.74 100.00
34 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82 100.00
35 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63 100.00
36 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88 100.00
37 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59 100.00
38 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 100.00
39 INT171939 Binding of HLA-DOA and TNF 1 0.05 6.8 0.26 100.00
40 INT10177 Binding of Ptafr and Gtf3a 1 0.02 1.34 0.28 100.00
41 INT113243 TNF Positive_regulation of Transcription of OPRM1 1 0.23 0.84 0.51 100.00
42 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19 100.00
43 INT113241 TRAF3IP2 Regulation of Transcription of OPRM1 1 0.05 0.82 0.52 100.00
44 INT317319 Binding of Trap1 and Pink1 1 0.26 2.67 0 100.00
45 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 100.00
46 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42 100.00
47 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4 100.00
48 INT168256 Binding of MLL and TNFRSF1B 1 0.00 1.2 0.53 100.00
49 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62 100.00
50 INT168459 Sult1a1 Negative_regulation of Gene_expression of Arr3 1 0.05 2.98 1.23 100.00
51 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 100.00
52 INT100726 TNF Positive_regulation of Gene_expression of F2RL1 2 0.27 1.9 0.46 100.00
53 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44 100.00
54 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07 100.00
55 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61 100.00
56 INT60523 Binding of IL1B and TNFRSF1A 1 0.25 1.73 0.21 100.00
57 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11 100.00
58 INT83626 Ifng Positive_regulation of Gene_expression of Cd59 1 0.33 2.19 1.41 100.00
59 INT160590 CSF2 Positive_regulation of Gene_expression of OPRM1 1 0.16 0.54 1.35 100.00
60 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35 100.00
61 INT160587 IFNG Positive_regulation of Gene_expression of OPRM1 1 0.18 0.54 1.35 100.00
62 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22 100.00
63 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15 100.00
64 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15 100.00
65 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15 100.00
66 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14 100.00
67 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13 100.00
68 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12 100.00
69 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09 100.00
70 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09 100.00
71 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8 100.00
72 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78 100.00
73 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78 100.00
74 INT187171 Binding of Tnfrsf1b and Gtf3a 1 0.03 2.15 0.72 100.00
75 INT148580 TNF Regulation of Gene_expression of SAMD9 1 0.48 3.01 0.5 100.00
76 INT233513 Pklr Negative_regulation of Localization of Il10 1 0.04 1.12 0.39 100.00
77 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33 100.00
78 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33 100.00
79 INT101219 TNF Negative_regulation of Gene_expression of EPO 1 0.47 2.8 0.3 100.00
80 INT101220 TNF Negative_regulation of EPO 1 0.48 2.8 0.3 100.00
81 INT233515 Pklr Positive_regulation of Gene_expression of Tnf 1 0.05 1.12 0.27 100.00
82 INT193781 SDF2L1 Positive_regulation of Localization of TNF 1 0.03 1.5 0.11 100.00
83 INT210595 Binding of TNF and TNFSF11 1 0.10 5.13 0.09 100.00
84 INT197651 TNF Regulation of PTH 1 0.05 1.67 0 100.00
85 INT197643 TNF Regulation of VDR 1 0.04 1.67 0 100.00
86 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15 100.00
87 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9 100.00
88 INT119107 Negative_regulation of Binding of LTBR and TNF 1 0.17 1.16 0.68 100.00
89 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65 100.00
90 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67 100.00
91 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67 100.00
92 INT315061 PAR4 Positive_regulation of Gene_expression of TNF 1 0.10 1.95 0 100.00
93 INT274077 Binding of Tnfrsf1b and Positive_regulation of Mapk8 1 0.14 0.97 0 100.00
94 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1 100.00
95 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08 100.00
96 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26 100.00
97 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 100.00
98 INT75738 Ltf Negative_regulation of Tnf 1 0.31 0.39 0.13 100.00
99 INT61360 Regulation of TNF Positive_regulation of NFKB1 2 0.21 1.34 0.14 100.00
100 INT149628 Il1b Regulation of Gene_expression of Ptgs2 1 0.30 0.84 0.84 100.00
101 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 100.00
102 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83 100.00
103 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59 100.00
104 INT8402 Tnf Regulation of Gene_expression of Vip 1 0.02 0.38 0.56 100.00
105 INT8400 Tnf Regulation of Gene_expression of Nts 1 0.00 0.38 0.56 100.00
106 INT8401 Il1a Regulation of Gene_expression of Nts 1 0.00 0.38 0.56 100.00
107 INT8395 Il1a Regulation of Gene_expression of Vip 1 0.01 0.38 0.56 100.00
108 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02 100.00
109 INT8396 Il1a Regulation of Nts 1 0.00 0.38 0.53 100.00
110 INT8397 Tnf Regulation of Nts 1 0.00 0.38 0.53 100.00
111 INT8399 Il1a Regulation of Vip 1 0.00 0.38 0.53 100.00
112 INT8398 Tnf Regulation of Vip 1 0.01 0.38 0.53 100.00
113 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54 100.00
114 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48 100.00
115 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48 100.00
116 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48 100.00
117 INT150534 OPRM1 Positive_regulation of TNF 1 0.03 0.38 0.48 100.00
118 INT150535 OPRM1 Positive_regulation of Positive_regulation of TNF 1 0.08 0.38 0.48 100.00
119 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83 100.00
120 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13 100.00
121 INT157150 Positive_regulation of PTGIR Negative_regulation of Gene_expression of TNF 1 0.12 0.97 0.34 100.00
122 INT146893 TNF Negative_regulation of Dkk1 1 0.01 1.27 0.3 100.00
123 INT4876 Regulation of TNF Regulation of MME 1 0.37 0.36 0.37 100.00
124 INT100946 TNF Positive_regulation of Localization of NFIB 1 0.01 1.3 0.29 100.00
125 INT100945 TNF Positive_regulation of NFIB 1 0.00 1.29 0.29 100.00
126 INT51475 Binding of Il6 and Tnf 1 0.15 0.61 0.43 100.00
127 INT146699 Nfkb1 Regulation of Gene_expression of TNF 1 0.20 0.72 0.27 100.00
128 INT146697 REL Regulation of Gene_expression of TNF 1 0.29 0.72 0.26 100.00
129 INT146701 Nfkb1 Regulation of Gene_expression of TNF 1 0.02 0.72 0.26 100.00
130 INT132809 TNF Positive_regulation of IL1B 2 0.33 1.26 0.16 100.00
131 INT132815 Positive_regulation of TNF Positive_regulation of CCL2 1 0.21 0.6 0.09 100.00
132 INT132808 Positive_regulation of TNF Positive_regulation of IL1B 1 0.33 0.6 0.09 100.00
133 INT132791 TNF Positive_regulation of KITLG 1 0.12 0.6 0.08 100.00
134 INT132814 TNF Positive_regulation of CCL2 1 0.21 0.6 0.08 100.00
135 INT259016 Positive_regulation of Binding of TNFSF18 and Relt 1 0.06 0.67 0 100.00
136 INT259018 Positive_regulation of Binding of TNFSF18 and Tnfrsf18 1 0.11 0.67 0 100.00
137 INT259015 Binding of TNFSF18 and Relt 1 0.04 0.67 0 100.00
138 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77 100.00
139 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26 100.00
140 INT287697 QRFP Regulation of Gene_expression of TNF 1 0.40 1.23 0.42 100.00
141 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12 100.00
142 INT161653 Gsr Regulation of Gene_expression of Ifih1 1 0.04 1.05 0.46 100.00
143 INT167200 Gtf3a Regulation of Gene_expression of Ngf 1 0.08 1.47 1.6 100.00
144 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6 100.00
145 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52 100.00
146 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29 100.00
147 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06 100.00
148 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06 100.00
149 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05 100.00
150 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05 100.00
151 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05 100.00
152 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05 100.00
153 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88 100.00
154 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88 100.00
155 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87 100.00
156 INT160412 Tat Positive_regulation of Transcription of Nos2 1 0.37 0.98 0.86 100.00
157 INT160413 Tat Positive_regulation of Gene_expression of Cd40lg 1 0.50 0.98 0.86 100.00
158 INT164227 Binding of PAEP and Tnfrsf11b 1 0.00 1.18 0.77 100.00
159 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71 100.00
160 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7 100.00
161 INT117533 TNF Positive_regulation of Positive_regulation of SETBP1 1 0.34 0.29 0.7 100.00
162 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7 100.00
163 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 0.06 1.09 0.7 100.00
164 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69 100.00
165 INT154530 Positive_regulation of Ifng Negative_regulation of Il10 1 0.33 0.63 0.61 100.00
166 INT327164 RETNLB Regulation of TNF 1 0.00 2.27 0.6 100.00
167 INT112869 Aap Positive_regulation of Gpt 2 0.26 0.75 0.6 100.00
168 INT143426 Positive_regulation of B4GALNT1 Negative_regulation of Gene_expression of Nos2 1 0.00 0.83 0.58 100.00
169 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56 100.00
170 INT146112 Binding of Il1b and Tnf 1 0.32 1.19 0.56 100.00
171 INT221033 TNF Positive_regulation of Gene_expression of CCL18 1 0.29 0.76 0.52 100.00
172 INT172082 TNF Regulation of SFTPA1 1 0.05 0.85 0.5 100.00
173 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49 100.00
174 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49 100.00
175 INT252426 Binding of SLURP1 and Negative_regulation of Gene_expression of TNF 1 0.01 1.13 0.49 100.00
176 INT187796 Binding of Tnf and Il1 1 0.09 1.85 0.48 100.00
177 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48 100.00
178 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48 100.00
179 INT187795 Positive_regulation of Binding of Tnf and Il1 1 0.13 1.87 0.48 100.00
180 INT161662 Gsr Regulation of Gene_expression of TNF 1 0.01 0.93 0.46 100.00
181 INT171123 TNF Positive_regulation of Localization of Spg7 1 0.01 1.35 0.46 100.00
182 INT161652 Gsr Regulation of Gene_expression of Tnf 1 0.17 0.98 0.46 100.00
183 INT173936 Hrt1 Regulation of Gtf3a 1 0.00 1.16 0.44 100.00
184 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43 100.00
185 INT230500 Il1 Positive_regulation of Gene_expression of Tnf 1 0.07 1.83 0.4 100.00
186 INT134761 Ghrl Regulation of Localization of Tnf 1 0.20 0.76 0.4 100.00
187 INT168463 Sult1a1 Negative_regulation of TNF 1 0.01 1 0.4 100.00
188 INT168458 Sult1a1 Negative_regulation of Tnf 1 0.09 1 0.4 100.00
189 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38 100.00
190 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38 100.00
191 INT109091 Tnf Positive_regulation of Localization of Il1b 1 0.56 1.08 0.36 100.00
192 INT110994 Tnf Regulation of Il6 1 0.17 0.67 0.36 100.00
193 INT54570 Positive_regulation of NFKB1 Positive_regulation of Gene_expression of IL8 1 0.24 0.77 0.35 100.00
194 INT330620 S100a8 Positive_regulation of Positive_regulation of TNF 1 0.03 1.92 0.32 100.00
195 INT100725 TNF Positive_regulation of Localization of SPG21 1 0.28 0.66 0.31 100.00
196 INT137418 MAPK7 Negative_regulation of Gene_expression of TNF 1 0.01 0.63 0.28 100.00
197 INT103156 Tnf Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.94 0.27 100.00
198 INT114389 Csf3 Negative_regulation of Localization of Tnf 1 0.02 0.46 0.26 100.00
199 INT107955 Gtf3a Positive_regulation of Hdc 1 0.07 0.3 0.26 100.00
200 INT135965 Calca Negative_regulation of Gene_expression of Tnf 1 0.33 0.72 0.26 100.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Necrosis. They are ordered first by their pain relevance and then by number of times they were reported in Necrosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
2 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 100.00
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 100.00
4 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 100.00
5 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 100.00
6 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
8 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
9 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 100.00
10 INT9660 Regulation of TNF 363 0.62 312.94 139.99 100.00
11 INT6481 Binding of TNF 624 0.48 510.2 214.82 100.00
12 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 100.00
13 INT10166 Localization of Tnf 237 0.81 153.95 88.64 100.00
14 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
15 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 100.00
16 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
17 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 100.00
18 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 100.00
19 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
20 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 100.00
21 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 100.00
22 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
23 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 100.00
24 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 100.00
25 INT80681 Positive_regulation of Atn1 20 0.49 11.85 3.76 100.00
26 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 100.00
27 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
28 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 100.00
29 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16 100.00
30 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 100.00
31 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 100.00
32 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 100.00
33 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 100.00
34 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 100.00
35 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 100.00
36 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 100.00
37 INT12082 Localization of IL6 365 0.81 241.78 105.78 100.00
38 INT35406 Localization of Tnf 94 0.81 64.63 31.65 100.00
39 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 100.00
40 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 100.00
41 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 100.00
42 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 100.00
43 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 100.00
44 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 100.00
45 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 100.00
46 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 100.00
47 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 100.00
48 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 100.00
49 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 100.00
50 INT297674 Gene_expression of Atn1 11 0.29 6.69 2 100.00
51 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 100.00
52 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 100.00
53 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 100.00
54 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63 100.00
55 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 100.00
56 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 100.00
57 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 100.00
58 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 100.00
59 INT6849 Localization of IL1B 229 0.81 112.56 69.63 100.00
60 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 100.00
61 INT53574 Regulation of Tnf 45 0.62 40.68 19.71 100.00
62 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 100.00
63 INT19511 Localization of Il6 212 0.81 118.17 67.67 100.00
64 INT15511 Gene_expression of Tnfrsf1a 84 0.76 63.3 24.03 100.00
65 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23 100.00
66 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 100.00
67 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 100.00
68 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 100.00
69 INT13354 Transcription of TNF 108 0.72 85.81 42.32 100.00
70 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36 100.00
71 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54 100.00
72 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 100.00
73 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75 100.00
74 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 100.00
75 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 100.00
76 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
77 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 100.00
78 INT9210 Regulation of IL6 166 0.62 125.61 49.95 100.00
79 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65 100.00
80 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 100.00
81 INT12339 Localization of IL8 437 0.81 251.87 117.39 100.00
82 INT11937 Localization of Il6 228 0.81 139.83 64.39 100.00
83 INT66755 Transcription of Tnf 45 0.72 37.1 19.11 100.00
84 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 100.00
85 INT10173 Binding of Tnf 45 0.48 35.6 14.32 100.00
86 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 100.00
87 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 100.00
88 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 100.00
89 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 100.00
90 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 100.00
91 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 100.00
92 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 100.00
93 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 100.00
94 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 100.00
95 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
96 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74 100.00
97 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 100.00
98 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 100.00
99 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 100.00
100 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 100.00
101 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 100.00
102 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 100.00
103 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 100.00
104 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78 100.00
105 INT49986 Transcription of Tnf 25 0.72 18.3 16.22 100.00
106 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 100.00
107 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 100.00
108 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 100.00
109 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 100.00
110 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 100.00
111 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33 100.00
112 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 100.00
113 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 100.00
114 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 100.00
115 INT86437 Binding of IL6 154 0.48 121.22 29.3 100.00
116 INT22454 Regulation of Crp 213 0.62 160.67 49.24 100.00
117 INT52899 Positive_regulation of TNFRSF1A 16 0.46 19.04 3.34 100.00
118 INT11807 Gene_expression of Il2 266 0.78 112 64.97 100.00
119 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 100.00
120 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56 100.00
121 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 100.00
122 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 100.00
123 INT74286 Regulation of Il10 42 0.44 28.06 19.44 100.00
124 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 100.00
125 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 100.00
126 INT9655 Regulation of Il6 98 0.62 70.92 31.95 100.00
127 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 100.00
128 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 100.00
129 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 100.00
130 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 100.00
131 INT2393 Positive_regulation of Mb 174 0.69 93.59 26.79 100.00
132 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 100.00
133 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 100.00
134 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 100.00
135 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 100.00
136 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 100.00
137 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 100.00
138 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 100.00
139 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 100.00
140 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9 100.00
141 INT19775 Localization of Il1 183 0.78 145.5 50.91 100.00
142 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 100.00
143 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 100.00
144 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 100.00
145 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 100.00
146 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 100.00
147 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 100.00
148 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41 100.00
149 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93 100.00
150 INT51474 Binding of Il6 55 0.48 44.99 20.52 100.00
151 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 100.00
152 INT69878 Positive_regulation of Gene_expression of Gtf3a 48 0.29 36.78 13.57 100.00
153 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48 100.00
154 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 100.00
155 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 100.00
156 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 100.00
157 INT10835 Regulation of IL8 79 0.49 53.04 24.14 100.00
158 INT54572 Negative_regulation of Positive_regulation of NFKB1 46 0.58 21.45 15.47 100.00
159 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82 100.00
160 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 100.00
161 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 100.00
162 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64 100.00
163 INT6484 Binding of IL1B 122 0.47 75.84 35.07 100.00
164 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 100.00
165 INT57692 Positive_regulation of Gene_expression of Il1b 50 0.67 43.54 28.29 100.00
166 INT100026 Gene_expression of Tnfrsf1b 73 0.72 43.26 23.23 100.00
167 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71 100.00
168 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 100.00
169 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 100.00
170 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 100.00
171 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 100.00
172 INT48890 Gene_expression of Gdnf 91 0.77 28.62 31.49 100.00
173 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 100.00
174 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 100.00
175 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 100.00
176 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 100.00
177 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 100.00
178 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 100.00
179 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 100.00
180 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39 100.00
181 INT48081 Localization of Il1b 46 0.80 21.59 22.4 100.00
182 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23 100.00
183 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 100.00
184 INT10763 Localization of IL2 157 0.80 81.11 33.21 100.00
185 INT5308 Regulation of Il1a 17 0.44 10.8 7.31 100.00
186 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64 100.00
187 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44 100.00
188 INT77789 Positive_regulation of Tnfrsf1b 12 0.65 13.77 6.58 100.00
189 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 100.00
190 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54 100.00
191 INT61953 Transcription of Nos2 101 0.72 46.64 25.49 100.00
192 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 100.00
193 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 100.00
194 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 100.00
195 INT86062 Positive_regulation of Tnfrsf1a 51 0.69 40.69 26.2 100.00
196 INT74629 Gene_expression of Mmp7 17 0.55 12.78 7.58 100.00
197 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02 100.00
198 INT14152 Gene_expression of Slc17a5 46 0.61 20.01 15.9 100.00
199 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28 100.00
200 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 100.00
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