D:Nemaline Myopathy

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Adult Onset Nemaline Myopathy, Autosomal Dominant Nemaline Myopathy, Autosomal Recessive Nemaline Myopathy, CHILDHOOD ONSET NEMALINE MYOPATHY, Late Onset Nemaline Myopathy, Myopathies Nemaline, Myopathies Rod, Myopathies Rod Body, Myopathy Nemaline, MYOPATHY ROD, Myopathy Rod Body
Documents 18
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nemaline Myopathy. They are ordered first by their relevance to Nemaline Myopathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 41.92
2 INT271071 Binding of ACTA1 and Hypism 1 0.00 1.54 0.15 7.48
3 INT331966 Binding of DES and SACM1L 1 0.01 1.86 0.36 5.00
4 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
5 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
6 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nemaline Myopathy. They are ordered first by their pain relevance and then by number of times they were reported in Nemaline Myopathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT296936 Positive_regulation of Localization of Tnnt1 1 0.34 2.38 0 100.00
2 INT296934 Positive_regulation of Localization of Tpm2 1 0.31 1.75 0 100.00
3 INT296933 Localization of Tnnt1 1 0.51 2.23 0 99.88
4 INT296935 Localization of Tpm2 1 0.46 1.6 0 99.88
5 INT296938 Positive_regulation of NEB 1 0.49 1.48 0 98.88
6 INT296939 Positive_regulation of Localization of TPM1 1 0.49 0.63 0 93.24
7 INT296937 Localization of TPM1 1 0.73 0.63 0 93.24
8 INT245157 Negative_regulation of Gene_expression of DMD 8 0.57 4.79 0.09 88.92
9 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 88.60
10 INT11713 Localization of RYR1 22 0.76 10.42 1.64 84.80
11 INT207779 Localization of Ap3d1 1 0.11 3.16 0.14 84.24
12 INT211753 Negative_regulation of ACADS 1 0.03 1.49 0.08 67.60
13 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 63.12
14 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 34.12
15 INT88416 Positive_regulation of Gene_expression of ACTA1 2 0.67 1.05 0.13 34.12
16 INT158175 Positive_regulation of Gene_expression of RYR1 2 0.48 1.35 0.13 34.12
17 INT331968 Positive_regulation of Gene_expression of SEPN1 1 0.31 1 0.13 34.12
18 INT331971 Positive_regulation of Gene_expression of DNM2 1 0.31 1 0.13 34.12
19 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64 33.44
20 INT289892 Gene_expression of SEPN1 3 0.42 1.17 0.13 33.20
21 INT71918 Gene_expression of ACTA1 16 0.75 7.73 1.45 32.92
22 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 32.64
23 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 32.28
24 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 28.88
25 INT180497 Binding of MRI1 45 0.42 28.35 14.77 21.64
26 INT121774 Binding of ACTA1 4 0.47 2.31 0.85 19.20
27 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
28 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
29 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
30 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
31 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
32 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 5.00
33 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
34 INT59555 Binding of RYR1 39 0.42 8.65 4.92 5.00
35 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66 5.00
36 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
37 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 5.00
38 INT21853 Regulation of Ap3d1 3 0.10 1.4 2.95 5.00
39 INT24712 Positive_regulation of Ap3d1 18 0.54 8.58 2.71 5.00
40 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 5.00
41 INT21852 Regulation of Gene_expression of Ap3d1 2 0.18 1.34 1.54 5.00
42 INT55305 Regulation of RYR1 14 0.45 5.27 1.33 5.00
43 INT11367 Localization of MB 9 0.78 9.34 1.24 5.00
44 INT42425 Gene_expression of Mmd 2 0.75 1.68 0.91 5.00
45 INT207780 Positive_regulation of NMS 2 0.28 3.2 0.61 5.00
46 INT207778 Positive_regulation of Binding of Ap3d1 1 0.06 1.26 0.52 5.00
47 INT94347 Gene_expression of DYSF 4 0.75 3.25 0.41 5.00
48 INT2090 Negative_regulation of Gaa 5 0.21 3.43 0.4 5.00
49 INT331973 Gene_expression of MYOT 4 0.64 3.83 0.4 5.00
50 INT211586 Regulation of DMPK 6 0.31 2.11 0.33 5.00
51 INT123637 Gene_expression of LGMD2I 2 0.08 1.7 0.29 5.00
52 INT260581 Binding of DMPK 7 0.43 5.09 0.28 5.00
53 INT264998 Regulation of Binding of MRI1 1 0.31 1.34 0.27 5.00
54 INT331969 Regulation of Gene_expression of MYOT 1 0.43 2.22 0.27 5.00
55 INT175417 Binding of SACM1L 8 0.29 6.06 0.22 5.00
56 INT49908 Regulation of Gene_expression of RYR1 3 0.45 0.32 0.19 5.00
57 INT179320 Regulation of LDB3 3 0.37 1.55 0.14 5.00
58 INT331970 Regulation of Regulation of LDB3 1 0.37 1.12 0.14 5.00
59 INT331967 Negative_regulation of LGMD2A 1 0.06 0.48 0.11 5.00
60 INT331972 Positive_regulation of Gene_expression of DYSF 1 0.28 0.48 0.11 5.00
61 INT211758 Binding of Mmd 1 0.13 3.09 0.1 5.00
62 INT211757 Negative_regulation of Mmd 1 0.11 1.02 0.08 5.00
63 INT272205 Positive_regulation of LGMD2I 2 0.12 2.08 0.08 5.00
64 INT207781 Gene_expression of CACNA1S 3 0.63 0.9 0.03 5.00
65 INT207782 Binding of CACNA1S 1 0.30 0.53 0.03 5.00
66 INT211756 Phosphorylation of Mmd 1 0.17 1.44 0.03 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox