D:Nephrosis

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pChart

Disease Term
Synonyms NEPHROSES
Documents 43
Hot Single Events 24
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nephrosis. They are ordered first by their relevance to Nephrosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT241778 AVP Positive_regulation of AVPR1A 1 0.10 1.32 0 67.92
2 INT21649 ANG Regulation of Alb 1 0.04 0.64 0.07 65.20
3 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 55.28
4 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 25.52
5 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 5.00
6 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 5.00
7 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 5.00
8 INT241777 Negative_regulation of Binding of AVP and TRGV9 1 0.10 0.75 0.13 5.00
9 INT241774 Binding of AVPR1A and TRGV9 1 0.02 0.48 0.09 5.00
10 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0 5.00
11 INT326979 HLN2 Negative_regulation of JPH3 1 0.02 2.05 0 5.00
12 INT326997 HSD11B1 Negative_regulation of Hdl2 1 0.12 2.06 0 5.00
13 INT241779 AVP Positive_regulation of TRGV9 1 0.17 0.48 0 5.00
14 INT326996 HLN2 Negative_regulation of Hdl2 1 0.06 2.05 0 5.00
15 INT241769 AVP Regulation of Binding of AVPR1A 1 0.11 0.49 0 5.00
16 INT241771 Binding of AVP and AVPR1B 1 0.04 0.49 0 5.00
17 INT326980 HSD11B1 Negative_regulation of JPH3 1 0.03 2.05 0 5.00
18 INT241768 Binding of AVP and AVPR1A 1 0.08 0.49 0 5.00
19 INT241770 AVP Regulation of Binding of TRGV9 1 0.11 0.49 0 5.00
20 INT241773 AVP Regulation of Binding of AVPR1B 1 0.05 0.49 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nephrosis. They are ordered first by their pain relevance and then by number of times they were reported in Nephrosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT214 Localization of AVP 370 0.81 208.51 91.09 99.16
2 INT17817 Binding of VUR 41 0.48 46.85 0.95 98.48
3 INT7678 Localization of Alb 142 0.81 80.93 22.49 98.12
4 INT160437 Gene_expression of Trpc6 24 0.78 9.09 4.75 98.00
5 INT34711 Localization of Engase 5 0.68 1.21 2.9 97.64
6 INT152060 Gene_expression of VUR 75 0.67 83.83 2.34 96.88
7 INT545 Binding of GC 15 0.45 10.74 3.47 96.84
8 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 96.82
9 INT147438 Gene_expression of Nox4 5 0.65 2.97 0.47 96.48
10 INT164304 Negative_regulation of Gene_expression of Trpc6 1 0.59 0.81 0.07 95.68
11 INT34708 Localization of B2m 1 0.66 0.67 2.52 94.32
12 INT34710 Binding of B2m 1 0.29 0.23 0.8 93.92
13 INT160438 Positive_regulation of Gene_expression of Trpc6 6 0.70 3.44 1.29 93.16
14 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 93.16
15 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 93.16
16 INT143779 Positive_regulation of Trpc6 3 0.70 2.22 0.9 93.16
17 INT164305 Positive_regulation of Nox4 2 0.42 1.6 0.53 93.16
18 INT164302 Positive_regulation of Gene_expression of Nox4 2 0.42 1.18 0.1 93.16
19 INT234 Binding of Alb 151 0.48 52.34 32.97 91.84
20 INT224924 Binding of TARM1 4 0.18 3.42 0.39 90.16
21 INT117313 Negative_regulation of VUR 11 0.42 12.14 0.39 90.00
22 INT56375 Positive_regulation of AMBP 25 0.60 21.24 2.22 87.92
23 INT312398 Positive_regulation of PCNT 3 0.40 0.75 0.53 86.12
24 INT5426 Negative_regulation of RTCA 58 0.51 12.34 25.74 82.16
25 INT164306 Regulation of Gene_expression of Trpc6 1 0.62 1.67 0.17 78.08
26 INT34714 Positive_regulation of B2m 3 0.66 2.78 1.86 77.92
27 INT34712 Positive_regulation of Localization of B2m 1 0.41 0.44 1.74 77.92
28 INT615 Regulation of Alb 66 0.62 33.43 15.33 77.60
29 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 77.60
30 INT21648 Regulation of Regulation of Alb 1 0.05 0.68 0.08 77.60
31 INT174652 Gene_expression of EXTL3 2 0.05 1.49 0.15 77.40
32 INT164307 Regulation of Trpc6 2 0.31 0.85 0.11 77.20
33 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 75.92
34 INT19847 Positive_regulation of Localization of Alb 21 0.70 13.89 4.16 75.92
35 INT27356 Localization of NEUROD1 8 0.78 3.44 1.39 75.00
36 INT44764 Localization of B4galnt1 1 0.59 0.26 0.29 75.00
37 INT44763 Regulation of B4galnt1 1 0.38 0.27 0.29 75.00
38 INT44765 Regulation of Localization of B4galnt1 1 0.23 0.27 0.29 75.00
39 INT3962 Regulation of AGT 50 0.62 20.96 13.01 74.52
40 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 72.04
41 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 65.84
42 INT34713 Positive_regulation of Engase 2 0.47 1.65 1.28 64.96
43 INT34709 Positive_regulation of Localization of Engase 1 0.59 0.22 0.91 64.96
44 INT241787 Negative_regulation of AQP2 1 0.57 1.38 0.03 55.28
45 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79 53.44
46 INT221858 Localization of TNKS 2 0.78 1.67 0.37 49.84
47 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 45.44
48 INT143780 Positive_regulation of Positive_regulation of Trpc6 2 0.47 0.72 0.41 43.60
49 INT82918 Binding of AMBP 23 0.39 23.31 1.71 36.24
50 INT188967 Negative_regulation of Binding of AMBP 2 0.03 2.7 0.39 36.24
51 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59 35.36
52 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 25.00
53 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 13.60
54 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 10.88
55 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 9.84
56 INT25539 Regulation of Gene_expression of AVP 9 0.45 2.74 0.89 9.84
57 INT695 Binding of POMC 304 0.48 56.66 126.85 5.00
58 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
59 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
60 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
61 INT685 Regulation of AVP 124 0.62 34.9 39.91 5.00
62 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 5.00
63 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61 5.00
64 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 5.00
65 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 5.00
66 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 5.00
67 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 5.00
68 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 5.00
69 INT684 Binding of AVP 38 0.48 13.9 8.85 5.00
70 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 5.00
71 INT5194 Positive_regulation of Lpo 63 0.70 26.44 8.37 5.00
72 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87 5.00
73 INT5195 Negative_regulation of Lpo 32 0.59 14.45 7.3 5.00
74 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 5.00
75 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 5.00
76 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54 5.00
77 INT150395 Binding of MEFV 55 0.44 31.18 3.42 5.00
78 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 5.00
79 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05 5.00
80 INT10848 Negative_regulation of Gene_expression of AVP 13 0.59 6.76 2.71 5.00
81 INT21721 Gene_expression of Lpo 25 0.60 16.33 2.57 5.00
82 INT112425 Gene_expression of TRGV9 15 0.58 7.34 2.49 5.00
83 INT46160 Regulation of Positive_regulation of AVP 4 0.53 0.99 2.14 5.00
84 INT80862 Negative_regulation of CYP3A5 5 0.57 1.66 2.13 5.00
85 INT56342 Gene_expression of TTR 34 0.78 16.5 2.05 5.00
86 INT45176 Negative_regulation of LPL 34 0.59 22.22 2.01 5.00
87 INT44223 Positive_regulation of TTR 10 0.70 10.98 1.95 5.00
88 INT174653 Localization of MEFV 15 0.70 12.06 1.93 5.00
89 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67 5.00
90 INT41986 Positive_regulation of Gene_expression of HSD11B1 26 0.49 32.84 1.52 5.00
91 INT20238 Regulation of APOB 9 0.61 11.52 1.26 5.00
92 INT8667 Localization of HSD11B1 22 0.73 22.74 1.25 5.00
93 INT118668 Negative_regulation of TRGV9 6 0.37 2.58 1.23 5.00
94 INT100328 Gene_expression of AQP2 6 0.75 2.41 1.21 5.00
95 INT23199 Binding of LDLR 22 0.47 17.08 1.16 5.00
96 INT98975 Positive_regulation of Hmgcr 7 0.16 3.4 1.06 5.00
97 INT17813 Positive_regulation of Hdl2 11 0.36 12.23 1.04 5.00
98 INT128609 Gene_expression of C1S 18 0.75 17.36 0.98 5.00
99 INT101687 Positive_regulation of AVPR1B 6 0.40 2.95 0.95 5.00
100 INT27220 Binding of CYP3A5 4 0.47 0.53 0.73 5.00
101 INT55975 Negative_regulation of Gene_expression of Lpo 6 0.31 3.44 0.72 5.00
102 INT153297 Regulation of MEFV 6 0.40 11.09 0.71 5.00
103 INT241788 Positive_regulation of Gene_expression of AQP2 3 0.67 1.26 0.7 5.00
104 INT21720 Negative_regulation of Positive_regulation of Lpo 8 0.43 2.98 0.69 5.00
105 INT45228 Gene_expression of Hdl2 13 0.48 18.05 0.67 5.00
106 INT200090 Positive_regulation of Gene_expression of Ldlr 5 0.37 3.67 0.59 5.00
107 INT103638 Negative_regulation of MEFV 7 0.39 5.88 0.54 5.00
108 INT9801 Regulation of TTR 3 0.45 1.4 0.48 5.00
109 INT165620 Negative_regulation of Gene_expression of HSD11B1 10 0.41 14.52 0.45 5.00
110 INT209189 Binding of AVPR1A 5 0.29 1.94 0.43 5.00
111 INT116725 Positive_regulation of CETP 19 0.49 16.33 0.36 5.00
112 INT8668 Regulation of Positive_regulation of HSD11B1 6 0.44 6.36 0.35 5.00
113 INT241790 Negative_regulation of AVPR1A 6 0.57 4.62 0.35 5.00
114 INT39390 Negative_regulation of Hdl2 8 0.43 9.83 0.35 5.00
115 INT177594 Binding of TRGV9 7 0.14 3.28 0.33 5.00
116 INT31581 Regulation of Hdl2 3 0.22 4.55 0.28 5.00
117 INT213281 Localization of LPL 3 0.21 3.48 0.28 5.00
118 INT85647 Transcription of HSD11B1 5 0.67 3.61 0.23 5.00
119 INT37790 Localization of Ldlr 5 0.38 2.29 0.23 5.00
120 INT45473 Positive_regulation of LIPC 3 0.20 5.49 0.2 5.00
121 INT187412 Negative_regulation of Cd320 5 0.42 3.09 0.18 5.00
122 INT112424 Gene_expression of AVPR1B 6 0.65 1.35 0.16 5.00
123 INT297577 Localization of APOA1 12 0.65 4.58 0.15 5.00
124 INT87196 Regulation of Hmgcr 3 0.45 0.7 0.14 5.00
125 INT200585 Negative_regulation of Binding of AVP 3 0.39 0.61 0.14 5.00
126 INT241783 Positive_regulation of AVPR1A 2 0.67 1.34 0.14 5.00
127 INT241292 Transcription of TRGV9 2 0.16 1.13 0.12 5.00
128 INT159425 Positive_regulation of Cd320 11 0.67 9.35 0.11 5.00
129 INT63110 Gene_expression of HLN2 2 0.65 2.15 0.08 5.00
130 INT63111 Gene_expression of JPH3 3 0.65 3.29 0.08 5.00
131 INT247116 Positive_regulation of SENP8 4 0.05 4.66 0.06 5.00
132 INT211567 Gene_expression of LIPC 1 0.09 1.55 0.05 5.00
133 INT211566 Localization of LIPC 3 0.61 2.31 0.05 5.00
134 INT348079 Negative_regulation of Negative_regulation of Ldlr 1 0.12 1.03 0.05 5.00
135 INT177599 Binding of AVPR1B 2 0.04 0.49 0.04 5.00
136 INT288855 Positive_regulation of JPH3 2 0.22 2.92 0.03 5.00
137 INT297432 Positive_regulation of Localization of Ldlr 2 0.14 0.35 0.03 5.00
138 INT326992 Phosphorylation of JPH3 1 0.16 2.15 0 5.00
139 INT229348 Binding of Hdl2 2 0.13 2.66 0 5.00
140 INT326982 Phosphorylation of Hdl2 1 0.28 2.16 0 5.00
141 INT326984 Negative_regulation of Localization of Hdl2 1 0.15 2 0 5.00
142 INT326981 Positive_regulation of Regulation of Hdl2 1 0.16 2.29 0 5.00
143 INT326990 Binding of JPH3 1 0.07 1.95 0 5.00
144 INT326983 Localization of Hdl2 1 0.26 3.75 0 5.00
145 INT326995 Localization of JPH3 1 0.15 1.82 0 5.00
146 INT262262 Negative_regulation of LRSAM1 2 0.03 1.34 0 5.00
147 INT326991 Negative_regulation of Localization of HSD11B1 1 0.29 3.92 0 5.00
148 INT326994 Regulation of JPH3 1 0.05 2.28 0 5.00
149 INT187665 Negative_regulation of Negative_regulation of HSD11B1 2 0.42 2.82 0 5.00
150 INT326985 Negative_regulation of Gene_expression of Hdl2 1 0.15 3.43 0 5.00
151 INT197740 Localization of CETP 2 0.53 2.42 0 5.00
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