D:Nephrotic Syndrome

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pChart

Disease Term
Synonyms Nephrotic Syndromes, Syndrome Nephrotic, SYNDROMES NEPHROTIC
Documents 7
Hot Single Events 10
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nephrotic Syndrome. They are ordered first by their relevance to Nephrotic Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT276589 Binding of Iqgap1 and Plce1 1 0.19 0.34 0 95.44
2 INT276582 Binding of Espn and Plce1 1 0.01 0.34 0 95.44
3 INT276587 Binding of Iqgap1 and Nphs1 1 0.08 0.33 0 92.56
4 INT276585 Binding of Trpc5 and Trpc6 1 0.17 0.26 0 89.84
5 INT257665 Binding of Nphs1 and Pard3 1 0.39 0.67 0.09 73.44
6 INT276590 Binding of Wt1 and KTWS 1 0.02 0.3 0 23.32
7 INT276586 Binding of Wt1 and Actn1 1 0.34 0.41 0 6.40
8 INT276591 Binding of Actn1 and KTWS 1 0.02 0.41 0 6.40
9 INT276583 Binding of Wt1 and IgG 1 0.07 0 0.04 5.00
10 INT257662 Binding of Mbp and Nphs1 1 0.11 0 0 5.00
11 INT257663 Binding of Nck1 and Nphs1 1 0.09 0 0 5.00
12 INT257666 Binding of Mgst1 and Pard3 1 0.05 0 0 5.00
13 INT257664 Regulation of Binding of Nphs1 and Pard3 1 0.36 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nephrotic Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Nephrotic Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT111298 Gene_expression of ACTN4 12 0.70 9.42 2.6 100.00
2 INT6301 Positive_regulation of Trpc6 8 0.67 4.15 1.59 98.56
3 INT143583 Positive_regulation of Nphs1 1 0.02 0.36 0.11 97.40
4 INT143585 Positive_regulation of NPHS2 1 0.49 0.36 0.11 97.40
5 INT143582 Positive_regulation of Actn4 1 0.05 0.36 0.11 97.40
6 INT143584 Positive_regulation of Cd2ap 1 0.16 0.35 0.11 97.40
7 INT110740 Binding of Trpc6 2 0.39 1.11 0 91.68
8 INT31964 Localization of Trpc6 4 0.65 0.63 0.3 89.84
9 INT276521 Binding of Trpc5 1 0.18 0.25 0 86.20
10 INT257647 Localization of Nphs1 1 0.71 0.34 0.05 83.60
11 INT145128 Gene_expression of Trpc6 12 0.75 5.59 1.17 73.96
12 INT243073 Gene_expression of Gsn 5 0.68 1.47 0.12 70.56
13 INT276526 Gene_expression of Myh10 1 0.67 1.4 0 70.56
14 INT276529 Gene_expression of Spnb2 1 0.57 0.37 0 70.56
15 INT276548 Gene_expression of Dbn1 1 0.53 0.38 0 70.56
16 INT241410 Gene_expression of Myh9 2 0.56 0.54 0 70.56
17 INT276555 Gene_expression of Actn1 1 0.59 0.76 0 70.56
18 INT202857 Gene_expression of Spna2 2 0.49 0.37 0 70.56
19 INT257641 Binding of Nphs1 1 0.46 0.33 0.04 70.04
20 INT257639 Binding of Pard3 1 0.35 0.4 0.04 70.04
21 INT276576 Negative_regulation of KTWS 1 0.02 0.75 0 53.08
22 INT276530 Negative_regulation of Wt1 5 0.53 2.97 0 53.08
23 INT257642 Gene_expression of Nphs1 4 0.66 0.96 0 50.64
24 INT276523 Negative_regulation of Gene_expression of Flna 2 0.48 0.8 0 45.20
25 INT276544 Gene_expression of Flna 3 0.63 1.97 0 44.52
26 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 40.44
27 INT276552 Gene_expression of Flnb 1 0.31 0.54 0 34.08
28 INT276518 Gene_expression of Flnc 1 0.37 0.54 0 33.68
29 INT276540 Positive_regulation of Gene_expression of Myh10 1 0.52 1.02 0 24.36
30 INT276574 Gene_expression of KTWS 1 0.04 0.5 0.08 22.00
31 INT276553 Gene_expression of Actn4 1 0.60 0.31 0 19.60
32 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7 19.20
33 INT85462 Binding of KTWS 3 0.31 2.91 0.54 11.96
34 INT168975 Binding of Wt1 14 0.43 7.37 0.07 11.96
35 INT114703 Positive_regulation of Wt1 5 0.46 4.25 0.24 8.04
36 INT276578 Positive_regulation of KTWS 1 0.03 0.42 0 7.84
37 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
38 INT12325 Gene_expression of Plec 47 0.72 11.92 13.35 5.00
39 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
40 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 5.00
41 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 5.00
42 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 5.00
43 INT48239 Binding of Gtf3a 52 0.33 23.14 6.45 5.00
44 INT31598 Gene_expression of Mgst1 41 0.78 6.44 6.3 5.00
45 INT26584 Gene_expression of Nes 76 0.75 24.03 4.17 5.00
46 INT185246 Gene_expression of Psmd1 26 0.50 8.89 3.73 5.00
47 INT276520 Gene_expression of Iqgap1 2 0.76 8.67 3.1 5.00
48 INT197446 Localization of Psmd1 10 0.56 3.78 2.79 5.00
49 INT118511 Gene_expression of Pard3 5 0.57 0.76 1.86 5.00
50 INT124092 Gene_expression of Myo1b 3 0.41 1.22 0.82 5.00
51 INT276535 Binding of Iqgap1 2 0.47 2.16 0.59 5.00
52 INT4642 Regulation of Regulation of IGHE 1 0.45 1.88 0.53 5.00
53 INT27115 Binding of Mbp 8 0.31 3.01 0.48 5.00
54 INT167897 Gene_expression of Ppp1r9b 3 0.58 0.32 0.48 5.00
55 INT75628 Gene_expression of Dst 4 0.60 0.78 0.31 5.00
56 INT232067 Gene_expression of RNPC3 6 0.65 0.95 0.2 5.00
57 INT217507 Localization of Tjp1 5 0.57 1.65 0.13 5.00
58 INT178195 Localization of Wt1 4 0.69 2.64 0.1 5.00
59 INT276543 Regulation of Iqgap1 2 0.27 0.49 0.08 5.00
60 INT207902 Binding of Mgst1 19 0.18 0.93 0.04 5.00
61 INT276541 Regulation of Myo6 1 0.04 0 0 5.00
62 INT257638 Positive_regulation of Nphs1 1 0.66 0.22 0 5.00
63 INT276571 Negative_regulation of Binding of KTWS 1 0.02 0 0 5.00
64 INT257644 Positive_regulation of Gene_expression of Nphs1 1 0.48 0 0 5.00
65 INT276547 Positive_regulation of Binding of Wt1 1 0.63 0.29 0 5.00
66 INT276536 Regulation of Pls3 1 0.11 0 0 5.00
67 INT214046 Gene_expression of UTRN 2 0.26 0.73 0 5.00
68 INT276545 Gene_expression of Pls3 1 0.10 0 0 5.00
69 INT276579 Regulation of KTWS 1 0.01 0 0 5.00
70 INT276525 Localization of Myh9 1 0.58 0.16 0 5.00
71 INT276572 Negative_regulation of Localization of KTWS 1 0.02 0 0 5.00
72 INT257643 Regulation of Nphs1 1 0.26 0.62 0 5.00
73 INT257650 Gene_expression of Nxf1 1 0.02 0.44 0 5.00
74 INT276528 Regulation of Myh9 1 0.23 0 0 5.00
75 INT276549 Binding of Actn4 1 0.32 0.61 0 5.00
76 INT257632 Binding of Kirrel 1 0.06 0.06 0 5.00
77 INT257636 Positive_regulation of Pard6a 1 0.18 0.06 0 5.00
78 INT276524 Regulation of Myo18a 1 0.04 0 0 5.00
79 INT276537 Localization of Myh10 1 0.65 0.16 0 5.00
80 INT276533 Localization of Dbn1 1 0.56 0.16 0 5.00
81 INT276522 Binding of Dbn1 1 0.29 0 0 5.00
82 INT276551 Positive_regulation of Localization of Wt1 1 0.45 0 0 5.00
83 INT276575 Transcription of KTWS 1 0.04 0 0 5.00
84 INT257651 Regulation of Binding of Nphs1 1 0.43 0 0 5.00
85 INT276519 Regulation of Wt1 2 0.24 1.7 0 5.00
86 INT276534 Negative_regulation of Binding of Wt1 1 0.38 0 0 5.00
87 INT276539 Regulation of Dbn1 1 0.09 0 0 5.00
88 INT257646 Positive_regulation of Gene_expression of Pard3 1 0.51 0 0 5.00
89 INT276573 Positive_regulation of Localization of KTWS 1 0.03 0 0 5.00
90 INT257633 Positive_regulation of Binding of Nphs1 1 0.66 0 0 5.00
91 INT276580 Localization of KTWS 1 0.04 0 0 5.00
92 INT276550 Transcription of Wt1 2 0.66 1.35 0 5.00
93 INT276527 Gene_expression of Shroom1 1 0.03 0 0 5.00
94 INT257637 Negative_regulation of Positive_regulation of Nphs1 1 0.41 0 0 5.00
95 INT276546 Regulation of Myo1b 1 0.16 0 0 5.00
96 INT276542 Binding of Myh9 1 0.40 0.61 0 5.00
97 INT276554 Binding of Myh10 1 0.32 0 0 5.00
98 INT257653 Negative_regulation of Binding of Pard3 1 0.32 0.07 0 5.00
99 INT276577 Positive_regulation of Binding of KTWS 1 0.03 0.29 0 5.00
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