D:Nerve Degeneration

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pChart

Disease Term
Synonyms Degeneration Nerve, Degeneration Neuron, DEGENERATIONS NERVE, DEGENERATIONS NEURON, Nerve Degenerations, NEURON DEGENERATION, Neuron Degenerations
Documents 130
Hot Single Events 99
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nerve Degeneration. They are ordered first by their relevance to Nerve Degeneration and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT298688 Binding of OPA1 and MFN1 1 0.52 2.09 0 98.00
2 INT298687 Binding of OPA1 and PARL 1 0.50 2.09 0 98.00
3 INT326587 GYPA Regulation of DDC 1 0.08 0.83 0.33 90.08
4 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6 85.36
5 INT162436 Binding of Igfals and Tardbp 1 0.16 2.68 0 82.76
6 INT162435 Binding of Igfals and Rapsn 1 0.19 1.34 0 82.76
7 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66 75.16
8 INT162437 Binding of Igf1 and Igfals 1 0.10 1.45 0 73.12
9 INT302675 Binding of OPA1 and PLAA 1 0.15 0.73 0 71.76
10 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64 52.00
11 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 51.44
12 INT178720 NOVA2 Regulation of Fig4 1 0.01 0 0.23 50.00
13 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0 49.32
14 INT264678 Binding of SETX and KRT20 1 0.00 2.17 0 48.72
15 INT264682 Binding of VAPB and SETX 1 0.28 1.09 0 48.28
16 INT324692 Binding of Cd14 and Sod1m 1 0.01 1.07 0.03 44.40
17 INT326573 Zic2 Positive_regulation of Localization of Hsf1 1 0.01 0.95 0.07 43.16
18 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11 39.16
19 INT326583 GYPA Negative_regulation of Binding of GYPA and SLC6A3 1 0.03 0.22 0.22 38.52
20 INT256227 Binding of EDN1 and VEGFA 1 0.18 2.92 0.25 25.24
21 INT256072 Serpina3k Negative_regulation of Positive_regulation of Ros1 1 0.04 0.49 0 21.84
22 INT215901 Ins1 Positive_regulation of Igfals 1 0.02 0.81 0.15 16.96
23 INT215902 Igfbp2 Positive_regulation of Igfals 1 0.15 0.8 0.15 16.96
24 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2 5.88
25 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 5.00
26 INT189999 Binding of Vta1 and Cfp 2 0.08 1.25 1.97 5.00
27 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35 5.00
28 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
29 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 5.00
30 INT261461 Positive_regulation of Akr1d1 Regulation of Sftpd 1 0.01 0 0.86 5.00
31 INT261458 Akr1d1 Regulation of Sftpd 1 0.01 0 0.82 5.00
32 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 5.00
33 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78 5.00
34 INT261447 Sftpd Positive_regulation of Akr1d1 1 0.01 0 0.77 5.00
35 INT261453 Binding of Akr1d1 and Ptgdr 1 0.00 0.56 0.65 5.00
36 INT261457 Sftpd Positive_regulation of Vta1 1 0.10 0 0.63 5.00
37 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61 5.00
38 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53 5.00
39 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
40 INT261450 Binding of Sftpd and Ptgdr 1 0.08 0.19 0.47 5.00
41 INT288350 IFNA1 Positive_regulation of Localization of Il6 1 0.01 1.49 0.46 5.00
42 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45 5.00
43 INT261451 Sftpd Positive_regulation of Ptgdr 1 0.09 0.05 0.45 5.00
44 INT262815 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.39 2.73 0.44 5.00
45 INT262819 Gene_expression of Serpinf1 Negative_regulation of Binding of 1190002H23Rik 1 0.05 2.66 0.43 5.00
46 INT342181 Binding of Igfals and Ros1 1 0.01 0.76 0.41 5.00
47 INT261464 Sftpd Regulation of Regulation of Ptgdr 1 0.08 0.07 0.41 5.00
48 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
49 INT262824 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.39 1.56 0.37 5.00
50 INT77791 fut10 Regulation of Regulation of Tnfrsf1a 1 0.02 0.85 0.36 5.00
51 INT261462 Akr1d1 Positive_regulation of Hrasls 1 0.00 0.3 0.33 5.00
52 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33 5.00
53 INT261452 Ptgdr Positive_regulation of Hrasls 1 0.02 0.3 0.33 5.00
54 INT77792 fut10 Negative_regulation of Positive_regulation of Tnfrsf1a 1 0.04 0.82 0.32 5.00
55 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3 5.00
56 INT262826 Serpinf1 Negative_regulation of Gene_expression of TNF 1 0.29 1.83 0.28 5.00
57 INT262820 Binding of Aif1 and Serpinf1 1 0.01 1.3 0.27 5.00
58 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25 5.00
59 INT324694 Tlr4 Positive_regulation of Gene_expression of Pnoc 1 0.05 0.56 0.24 5.00
60 INT261465 Binding of Drd1a and Ptgdr 1 0.03 0.1 0.23 5.00
61 INT261455 Sftpd Regulation of Ptgdr 1 0.11 0.09 0.23 5.00
62 INT192864 Binding of Hspa5 and Mela 1 0.25 1.06 0.22 5.00
63 INT262817 Serpinf1 Regulation of Positive_regulation of 1190002H23Rik 1 0.06 1.3 0.22 5.00
64 INT180600 MAOB Positive_regulation of TAC1 1 0.00 0.13 0.22 5.00
65 INT261459 Sftpd Negative_regulation of Ldha 1 0.08 0.63 0.18 5.00
66 INT288349 TNF Positive_regulation of Gene_expression of Mcpt1 1 0.02 1.1 0.18 5.00
67 INT262818 Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.45 0.71 0.18 5.00
68 INT262822 Serpinf1 Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.07 1.27 0.18 5.00
69 INT288351 Mcpt1 Positive_regulation of Gene_expression of TNF 1 0.02 1.1 0.18 5.00
70 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17 5.00
71 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17 5.00
72 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17 5.00
73 INT261460 Binding of Sftpd and Akr1d1 1 0.01 0.43 0.16 5.00
74 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 5.00
75 INT261456 Sftpd Positive_regulation of Gene_expression of Th 1 0.10 0.77 0.13 5.00
76 INT261448 Sftpd Positive_regulation of Phospho1 1 0.01 0.58 0.12 5.00
77 INT261449 Sftpd Positive_regulation of Gene_expression of Phospho1 1 0.01 0.58 0.12 5.00
78 INT324691 Tlr6 Positive_regulation of Rcvrn 1 0.01 0 0.12 5.00
79 INT324695 Tlr6 Positive_regulation of Tlr2 1 0.14 0 0.12 5.00
80 INT283539 Binding of Litaf and Mad2l1bp 1 0.00 0.67 0.11 5.00
81 INT303815 Binding of Igfals and Tdp1 1 0.11 1.68 0.1 5.00
82 INT192863 Binding of Ddit3 and Esr1 1 0.09 0.67 0.08 5.00
83 INT192860 Binding of Calr and Esr1 1 0.06 0.67 0.08 5.00
84 INT192865 Binding of Esr1 and Pdia3 1 0.07 0.67 0.08 5.00
85 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08 5.00
86 INT326574 Binding of Akt1 and Hsp90ab1 1 0.13 0.17 0.08 5.00
87 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08 5.00
88 INT262825 Serpinf1 Negative_regulation of Gfap 1 0.34 0.87 0.08 5.00
89 INT208555 YWHAQ Positive_regulation of Atxn1 1 0.77 1.02 0.08 5.00
90 INT208554 Phosphorylation of YWHAQ Positive_regulation of Binding of YWHAQ and Akt1 1 0.32 1.04 0.08 5.00
91 INT208556 Binding of YWHAQ and Akt1 1 0.22 1.02 0.08 5.00
92 INT262821 Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.54 0.85 0.08 5.00
93 INT261454 Akr1d1 Regulation of Drd1a 1 0.00 0.71 0.06 5.00
94 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05 5.00
95 INT303500 Regulation of Ebf2 Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.13 0.16 0.05 5.00
96 INT326571 Binding of Hsf1 and Hsp90ab1 1 0.16 1.19 0.03 5.00
97 INT256228 EDNRB Positive_regulation of EDN1 1 0.26 0.62 0.03 5.00
98 INT326570 Hsp90ab1 Regulation of Csprs 1 0.08 1.17 0.03 5.00
99 INT331234 Binding of Becn1 and Pik3c3 Positive_regulation of Pik3c3 1 0.00 0.47 0 5.00
100 INT331226 Binding of Becn1 and Pik3c3 1 0.02 0.47 0 5.00
101 INT331238 Binding of ULK1 and Pik3r1 1 0.09 0.48 0 5.00
102 INT331237 Negative_regulation of IMPA1 Negative_regulation of Itpr3 1 0.00 0.52 0 5.00
103 INT256081 Serpina3k Negative_regulation of Ca2 1 0.05 0.07 0 5.00
104 INT331232 Binding of Atg12 and Atg16l1 1 0.03 0.08 0 5.00
105 INT256079 Serpina3k Negative_regulation of Fig4 1 0.07 0.16 0 5.00
106 INT282995 Binding of Bcl2 and Becn1 21 0.03 9.8 0 5.00
107 INT256082 Serpina3k Negative_regulation of Positive_regulation of Fig4 1 0.07 0.16 0 5.00
108 INT283543 Binding of GARS and Setx 1 0.01 3.71 0 5.00
109 INT331222 Tsc1 Negative_regulation of Mtor 1 0.00 0.68 0 5.00
110 INT331235 RASA1 Positive_regulation of Mtor 1 0.00 0.32 0 5.00
111 INT299232 Onc1 Regulation of Gene_expression of Aqp4 1 0.01 0.43 0 5.00
112 INT324696 Binding of Myd88 and Mapk10 1 0.05 0.68 0 5.00
113 INT256103 Serpina3k Negative_regulation of Positive_regulation of Hspg2 1 0.02 0.15 0 5.00
114 INT256076 Serpina3k Regulation of Ros1 1 0.02 0.56 0 5.00
115 INT256077 Serpina3k Positive_regulation of Gene_expression of Ca2 1 0.06 0.17 0 5.00
116 INT303822 Tdp1 Regulation of TREH 1 0.02 0.92 0 5.00
117 INT256073 Negative_regulation of Serpina3k Positive_regulation of Ca2 1 0.05 0.17 0 5.00
118 INT283542 Binding of SPG19 and Setx 1 0.06 3.69 0 5.00
119 INT331225 Binding of Atg5 and Atg16l1 1 0.05 0.08 0 5.00
120 INT331231 Binding of Bcl2 and Mapk8 1 0.01 0.77 0 5.00
121 INT302673 Zmat3 Negative_regulation of Binding of Sod1 and Sod1 1 0.04 0.16 0 5.00
122 INT331230 Binding of Mapk8 and Becn1 1 0.02 0.77 0 5.00
123 INT331228 Atg5 Positive_regulation of Atg12 1 0.06 0.08 0 5.00
124 INT299234 Onc1 Negative_regulation of Thy1 1 0.02 0.16 0 5.00
125 INT331224 Binding of Akt1 and Tsc2 1 0.03 0.33 0 5.00
126 INT264679 IGFALS Positive_regulation of CTSC 1 0.02 1.68 0 5.00
127 INT256104 Binding of Serpina3k and Positive_regulation of Positive_regulation of Hspg2 1 0.03 1 0 5.00
128 INT256075 Serpina3k Negative_regulation of Phosphorylation of Akt1 1 0.14 0.17 0 5.00
129 INT331223 Negative_regulation of Tsc1 Positive_regulation of Positive_regulation of Mtor 1 0.01 0.33 0 5.00
130 INT192866 Binding of Emb and Gpr85 1 0.07 0.06 0 5.00
131 INT256078 Serpina3k Regulation of Gene_expression of Ros1 1 0.02 0.56 0 5.00
132 INT256080 Serpina3k Positive_regulation of Ca2 1 0.06 0.17 0 5.00
133 INT331229 Rasa1 Positive_regulation of Mtor 1 0.00 0.32 0 5.00
134 INT196185 Binding of SEMA3A and Nrp1 1 0.01 0.05 0 5.00
135 INT331233 Binding of Mtor and Rasa1 1 0.00 0.32 0 5.00
136 INT331236 Binding of RASA1 and Mtor 1 0.00 0.32 0 5.00
137 INT302672 Gene_expression of Zmat3 Positive_regulation of Sod1 1 0.05 0.05 0 5.00
138 INT283544 Binding of GARS and Bscl2 1 0.01 1.74 0 5.00
139 INT192861 Binding of Emb and Mela 1 0.10 0.13 0 5.00
140 INT283533 Binding of GARS and SPG19 1 0.00 1.72 0 5.00
141 INT256074 Serpina3k Negative_regulation of Gene_expression of Ros1 1 0.04 0.64 0 5.00
142 INT349355 CSF2 Negative_regulation of CSTA 1 0.01 1.43 0 5.00
143 INT299233 Onc1 Regulation of Gene_expression of Aqp9 1 0.01 0.19 0 5.00
144 INT256105 Serpina3k Negative_regulation of Phosphorylation of Hspg2 1 0.02 0.2 0 5.00
145 INT302671 Zmat3 Positive_regulation of Gene_expression of Sod1 1 0.04 0.3 0 5.00
146 INT331221 Binding of Akt1 and Tsc1 1 0.03 0.33 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nerve Degeneration. They are ordered first by their pain relevance and then by number of times they were reported in Nerve Degeneration. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 99.66
2 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99 99.34
3 INT3463 Gene_expression of Igfals 21 0.39 21.1 2.93 99.04
4 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 98.92
5 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21 98.92
6 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 98.88
7 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 98.76
8 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 98.72
9 INT89360 Negative_regulation of Serpina3k 2 0.57 11.06 0.81 98.44
10 INT256094 Negative_regulation of Gene_expression of Serpina3k 1 0.57 4.5 0.1 98.44
11 INT256085 Gene_expression of Serpina3k 1 0.75 8.51 0.46 98.44
12 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 98.16
13 INT189809 Negative_regulation of HEXA 1 0.57 3.93 0 98.16
14 INT179550 Phosphorylation of Ywhaq 8 0.03 6.24 1.48 97.94
15 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 97.82
16 INT250272 Positive_regulation of Gene_expression of AQP4 11 0.54 9.79 1.85 97.64
17 INT5578 Regulation of da 10 0.39 2.92 7.26 97.56
18 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 97.56
19 INT189811 Negative_regulation of ATXN3 1 0.35 3.09 0 97.48
20 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53 97.44
21 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 97.24
22 INT264689 Negative_regulation of IGFALS 10 0.33 12.58 0.45 97.20
23 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 96.92
24 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 96.92
25 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 96.80
26 INT303796 Gene_expression of Tdp1 1 0.77 70.15 2.55 96.76
27 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 96.64
28 INT137332 Positive_regulation of Gene_expression of Sod1 41 0.70 19.8 4.69 95.96
29 INT187472 Regulation of Gene_expression of Sod1 5 0.53 2.68 0.37 95.96
30 INT116622 Positive_regulation of Nefh 17 0.39 11.98 3.86 95.48
31 INT139301 Regulation of Espn 1 0.02 0.38 0.24 94.40
32 INT200185 Regulation of Igfals 10 0.26 11.4 1.47 94.32
33 INT240280 Gene_expression of IGFALS 14 0.42 20.38 0.95 94.04
34 INT288331 Gene_expression of Sod1m 5 0.09 6.99 0.77 93.36
35 INT288330 Positive_regulation of Gene_expression of Sod1m 4 0.08 5.88 0.67 93.36
36 INT26584 Gene_expression of Nes 76 0.75 24.03 4.17 93.36
37 INT69221 Negative_regulation of Sod1 14 0.56 10.57 1.83 93.06
38 INT243382 Positive_regulation of CSTA 4 0.05 14.65 0.12 91.80
39 INT84572 Gene_expression of Zmat3 67 0.07 37.61 5.86 91.60
40 INT164116 Negative_regulation of 1190002H23Rik 33 0.51 18.73 2.71 91.36
41 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 91.32
42 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 91.32
43 INT162429 Negative_regulation of Gene_expression of Sod1 6 0.48 2.46 0.53 91.20
44 INT105569 Binding of IGFALS 13 0.25 17.31 1.36 91.12
45 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 90.92
46 INT140414 Positive_regulation of AQP4 25 0.64 23.43 2.47 90.64
47 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 90.52
48 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 90.04
49 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 89.88
50 INT18391 Positive_regulation of GYPA 41 0.40 16.47 8.69 89.84
51 INT15209 Negative_regulation of Regulation of Th 6 0.51 1.64 2.16 89.44
52 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55 89.28
53 INT95492 Gene_expression of Nefh 20 0.67 12.68 10.46 89.16
54 INT61118 Gene_expression of Nefl 11 0.75 4.02 4.02 89.16
55 INT56029 Gene_expression of Nefm 8 0.52 2.83 2.23 89.16
56 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 88.32
57 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19 88.04
58 INT149031 Gene_expression of Tjp1 43 0.75 19.1 2.06 87.24
59 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97 87.24
60 INT182474 Gene_expression of Cdh5 17 0.57 14.58 1.23 87.24
61 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 87.00
62 INT7327 Regulation of Th 164 0.62 29.67 110.14 86.64
63 INT174127 Positive_regulation of Positive_regulation of Sod1 2 0.45 4.9 0.19 86.60
64 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 86.56
65 INT2649 Regulation of Calca 433 0.62 146.05 330.95 86.48
66 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 86.48
67 INT51368 Regulation of Sub1 1 0.09 1.95 1.86 86.48
68 INT63037 Regulation of CSTA 10 0.37 13.37 0.92 86.32
69 INT69222 Positive_regulation of Sod1 15 0.61 8.19 1.87 85.92
70 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 85.36
71 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 84.88
72 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 84.84
73 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 84.80
74 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 84.80
75 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 84.80
76 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 84.36
77 INT39516 Gene_expression of Alb 81 0.75 30.08 6.59 84.16
78 INT11814 Positive_regulation of Alb 43 0.63 31.71 6.28 84.16
79 INT143095 Positive_regulation of Gene_expression of Alb 8 0.40 1.53 0.66 84.16
80 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 83.68
81 INT63036 Negative_regulation of CSTA 4 0.36 9.42 0.22 83.12
82 INT122577 Regulation of SLC6A3 9 0.53 1.47 3.09 82.88
83 INT303811 Binding of Tdp1 1 0.37 8.69 0.33 82.60
84 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 81.92
85 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 81.84
86 INT82882 Localization of Ccl2 61 0.80 41.96 28 81.84
87 INT299196 Transcription of Thy1 1 0.66 1.98 0 81.52
88 INT215900 Negative_regulation of Gene_expression of Mcam 1 0.42 2.65 0.42 81.20
89 INT215899 Negative_regulation of Gene_expression of Slc2a1 6 0.43 3.96 0.55 81.20
90 INT181738 Positive_regulation of Localization of Gtf3a 4 0.02 2.46 0.25 81.16
91 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 80.92
92 INT106969 Negative_regulation of Tgm1 1 0.07 0.62 0.07 80.88
93 INT56053 Negative_regulation of Bdnf 77 0.58 64.4 26.83 80.56
94 INT240281 Positive_regulation of IGFALS 11 0.31 10.44 0.56 80.56
95 INT264686 Positive_regulation of Gene_expression of IGFALS 2 0.28 2.21 0.27 80.56
96 INT215897 Gene_expression of Mcam 10 0.75 4.68 0.81 80.48
97 INT55291 Gene_expression of Slc2a1 20 0.68 11.46 2.16 80.48
98 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 80.16
99 INT331198 Negative_regulation of Dctn1 1 0.01 0.58 0 80.16
100 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 80.00
101 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 79.72
102 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64 79.72
103 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 79.72
104 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 79.72
105 INT63035 Gene_expression of CSTA 10 0.56 11.56 0.57 79.44
106 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 79.32
107 INT326602 Negative_regulation of Gene_expression of SLC18A2 1 0.25 0.93 0.67 78.88
108 INT278334 Negative_regulation of Hsp90ab1 3 0.30 4.34 0.68 78.80
109 INT326601 Gene_expression of SLC18A2 2 0.42 1.31 0.92 78.48
110 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 78.08
111 INT69990 Negative_regulation of Nefl 11 0.59 2.82 3.38 77.68
112 INT35391 Negative_regulation of Nefm 7 0.27 3.17 1.73 77.44
113 INT222241 Binding of Ccr2 5 0.42 4.09 3.71 77.24
114 INT95499 Negative_regulation of Nefh 9 0.59 8.97 7.13 77.20
115 INT26487 Positive_regulation of Npr1 17 0.70 10.01 8.78 77.12
116 INT331205 Protein_catabolism of Gdnf 1 0.03 0.57 0 76.80
117 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 76.36
118 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 76.00
119 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39 75.36
120 INT160799 Regulation of IGFALS 11 0.29 9.09 0.7 75.32
121 INT4535 Localization of PROC 106 0.73 76.24 21.1 75.04
122 INT55979 Protein_catabolism of PROC 8 0.22 2.8 1.49 75.04
123 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 75.00
124 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36 75.00
125 INT127607 Gene_expression of EID1 4 0.63 5.57 1.6 75.00
126 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 75.00
127 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 75.00
128 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 75.00
129 INT6558 Positive_regulation of Gene_expression of Th 56 0.70 9.64 30.89 75.00
130 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92 75.00
131 INT79489 Transcription of Adra2a 2 0.61 2.38 1.22 75.00
132 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19 75.00
133 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 74.92
134 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 74.92
135 INT349357 Negative_regulation of Transcription of CSTA 1 0.02 1.26 0 74.24
136 INT349362 Transcription of CSTA 1 0.02 1.38 0 74.24
137 INT349360 Positive_regulation of Transcription of CSTA 1 0.02 1.25 0 74.24
138 INT36177 Binding of Alms1 70 0.31 35.47 13.81 74.16
139 INT303808 Positive_regulation of Gene_expression of Tdp1 1 0.69 9.07 0.35 73.44
140 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 72.24
141 INT1180 Gene_expression of Ren 63 0.77 27.33 10.51 72.24
142 INT236094 Localization of Gdnf 4 0.70 2.51 0.68 72.08
143 INT243236 Localization of Nefl 3 0.73 1.57 0 72.08
144 INT149349 Regulation of Atf3 8 0.45 10 3.85 71.60
145 INT346446 Negative_regulation of Regulation of Atf3 1 0.38 0.58 0.39 71.60
146 INT72532 Regulation of Gene_expression of Il1a 13 0.54 4.91 6.71 71.24
147 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 70.68
148 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16 69.96
149 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58 69.76
150 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3 69.72
151 INT60461 Positive_regulation of Gene_expression of Il1a 40 0.61 17.23 12.35 69.44
152 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 69.36
153 INT164115 Gene_expression of 1190002H23Rik 11 0.58 5.18 1.17 69.36
154 INT32336 Positive_regulation of da 16 0.42 4.69 12.38 68.88
155 INT32335 Positive_regulation of Positive_regulation of da 1 0.02 0.16 0.44 68.88
156 INT110961 Binding of GYPA 14 0.36 6.66 2.03 68.64
157 INT5913 Binding of OPA1 12 0.41 9.33 2.92 68.16
158 INT310891 Gene_expression of 53T 28 0.50 35.4 7.17 67.68
159 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32 67.44
160 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 67.20
161 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03 67.20
162 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 67.04
163 INT18190 Regulation of DRD2 11 0.60 9.01 7.63 66.96
164 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93 66.96
165 INT326603 Regulation of Positive_regulation of DRD2 1 0.44 0.8 0.69 66.96
166 INT144918 Gene_expression of Thy1 5 0.62 4.39 0.06 66.72
167 INT89677 Gene_expression of PRKG1 38 0.78 13.98 8.56 66.48
168 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 66.20
169 INT158056 Localization of Nrg1 13 0.79 3.11 1.28 65.96
170 INT10980 Gene_expression of GYPA 40 0.78 15.32 5.51 65.88
171 INT130560 Negative_regulation of Gene_expression of Serpinf1 17 0.58 13.39 1.94 65.64
172 INT155565 Gene_expression of Efemp2 22 0.67 7.24 0.13 65.36
173 INT10131 Gene_expression of Serpinf1 53 0.76 35.57 6.42 65.12
174 INT236089 Regulation of Negative_regulation of Hrec 1 0.03 1.56 0.55 64.88
175 INT236090 Regulation of Negative_regulation of S100a8 1 0.02 1.55 0.54 64.88
176 INT208643 Gene_expression of Gt(ROSA)26Sor 11 0.65 4.85 0.37 64.80
177 INT247871 Negative_regulation of Thy1 8 0.54 7.23 0.03 64.64
178 INT132246 Negative_regulation of S100a8 19 0.43 22 7.25 64.48
179 INT90372 Negative_regulation of Hrec 12 0.03 11.73 4.74 64.48
180 INT326598 Negative_regulation of Negative_regulation of SLC6A3 1 0.28 0.65 0.24 63.44
181 INT326557 Positive_regulation of Regulation of Zic2 1 0.02 1.07 0.09 63.00
182 INT50855 Gene_expression of TRIM21 4 0.65 3.07 0.71 62.40
183 INT326554 Regulation of Zic2 3 0.39 2.02 0.39 62.28
184 INT81210 Positive_regulation of PRKG1 71 0.70 26.83 19.89 62.08
185 INT127714 Negative_regulation of GEM 6 0.37 2.24 1.01 60.88
186 INT50895 Regulation of GYPA 10 0.60 4.05 1.95 60.64
187 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 60.24
188 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 60.08
189 INT303807 Gene_expression of LOC100360075 1 0.08 2.7 0.1 59.56
190 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1 57.56
191 INT299228 Regulation of Gene_expression of Thy1 1 0.22 1.47 0.03 56.96
192 INT157302 Positive_regulation of Map1lc3a 27 0.66 11.31 0.79 56.84
193 INT196164 Localization of SEMA3A 5 0.77 1.39 0.06 56.84
194 INT162430 Negative_regulation of Positive_regulation of Ar 1 0.21 1.52 0.07 54.80
195 INT76434 Negative_regulation of PRKG1 25 0.58 10.36 10.81 54.68
196 INT6852 Localization of TNF 883 0.81 705.95 270.84 54.16
197 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23 54.16
198 INT181803 Binding of Atxn1 12 0.48 7 0.3 54.00
199 INT162432 Positive_regulation of Ar 3 0.23 2.34 0.11 53.92
200 INT162428 Localization of Ar 4 0.37 2.4 0.07 53.92
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